CloudStack and OpenStack both provide platform for managing and deploying virtual infrastructure. CloudStack UI is easier to use and more user friendly, while OpenStack UI is simpler but based on Django framework. CloudStack uses monolithic controller architecture with datacenter model, while OpenStack is more fragmented with shared nothing architecture. CloudStack networking supports basic, advanced, flat and VLAN modes. OpenStack uses security groups and supports flat, DHCP and VLAN modes. CloudStack storage is primary and secondary, while OpenStack uses Cinder for block storage and Swift for object storage. CloudStack deployment is easier while OpenStack typically requires tools like Puppet or Chef.