Beauty Nectar Collagen Drink is the anti-aging solution for all your aging issues. Reduce wrinkles and get Glowing skin with best Collagen Drink by Ashieda.
Formulation, Development and Evaluation of Herbal Antiaging Creamijtsrd
In this study creams were formulated based on the anti aging properties of herbal extracts and its evaluation. Ocimum tenuiflorum used as an active ingredients and extract as a Antibacterial property in these study cream are formulated by oil in water emulsion method. The cream were formulated with Aloeveragel, stearic acid, honey, Glycerin, olive oil, rose oil. The Stability for cream was performed at accelerated condition i.e. 40°C ± 2°C.If can be concluded that herbal creams without side effects having anti bacterial property can be used as provision of a barrier to protect the skin and avoid aging of the skin. Suchita Ghokhale | Dr. Smita T | Roshani Nimgire | Kashi S Ojha | Ujwala Namsale | Anam Mulla "Formulation, Development and Evaluation of Herbal Antiaging Cream" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5 , August 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50672.pdf Paper URL: https://www.ijtsrd.com/pharmacy/other/50672/formulation-development-and-evaluation-of-herbal-antiaging-cream/suchita-ghokhale
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative O...Mark Babizhayev
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine. Int J Clin Dermatol Res. 5(5), 116-143.
Collagen : Foundation of youth or edible hoax - DR Naveen (BDS)Dr Naveen Gokul R
SAVEETHA INTERNATIONAL CONFERENCE 2018
SECURED 1ST PLACE
Guided by - Prof PRISCILLA (biochemistry)
Collagen is the main structural protein of the different connective tissues present in animals.
It is mostly found in fibrous tissues, such as tendons and ligaments, and is also abundant in the cornea, cartilage, bones, blood vessels, the gut, and intervertebral discs.
Collagen is the major insoluble fibrous protein found in the extracellular matrix of the skin, together with elastin and hyaluronic acid.
Reverse aging is one of the most important health benefits of collagen use
Ebook: The Insider's Guide on How to Look 10 Years YoungerAviva Pure
This Ebook walks you through step by step on how to make changes to your skin care routine and diet to knock off 10 years of aging. Learn the major factors that cause aging, where your skin is currently at in the aging process and tips from cultures around the world on looking younger.
PREPARATION AND CHARACTERIZATION OF THE POLY HERBAL ANTI-AGEING CREAMAvinash More
To prepare and evaluate the polyherbal cosmetic cream comprising extracts of natural products such as aloe, orange peel extract, punica extract and green tea. Extract of aloe (Aloe vera) and Citrus aurintum(orange peel) Green tea (Camelia sinensis) and pomegranate (Punica granatum)are well known for its medicinal value in Indian traditional system of medicine and in ayurvedic preparation. Present work, was based on extraction of these herbs and formulate poly herbal cosmetic cream.
Collagen comprises of about one third of total protein of our body
Collagen peptide ingestion results in more collagen-producing cells and increases the density of collagen in the skin.
Nizona’s Collagen Peptide has been clinically tested in Japan. Use of hydrolyzed collagen improves skin suppleness, hydration and elasticity which allows its users to look younger and be healthier.
Hydrolyzed collagen contains 20 amino acids, predominantly glycine, proline and hydroxyproline
Hydrolyzed collagen is absorbed as amino acids and small peptides in the blood
Hydrolyzed Japanese collagen reduces wrinkles and results in significant improvement in wrinkle depth, improvement in elasticity and hydration of the skin
Formulation, Development and Evaluation of Herbal Antiaging Creamijtsrd
In this study creams were formulated based on the anti aging properties of herbal extracts and its evaluation. Ocimum tenuiflorum used as an active ingredients and extract as a Antibacterial property in these study cream are formulated by oil in water emulsion method. The cream were formulated with Aloeveragel, stearic acid, honey, Glycerin, olive oil, rose oil. The Stability for cream was performed at accelerated condition i.e. 40°C ± 2°C.If can be concluded that herbal creams without side effects having anti bacterial property can be used as provision of a barrier to protect the skin and avoid aging of the skin. Suchita Ghokhale | Dr. Smita T | Roshani Nimgire | Kashi S Ojha | Ujwala Namsale | Anam Mulla "Formulation, Development and Evaluation of Herbal Antiaging Cream" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5 , August 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50672.pdf Paper URL: https://www.ijtsrd.com/pharmacy/other/50672/formulation-development-and-evaluation-of-herbal-antiaging-cream/suchita-ghokhale
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative O...Mark Babizhayev
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine. Int J Clin Dermatol Res. 5(5), 116-143.
Collagen : Foundation of youth or edible hoax - DR Naveen (BDS)Dr Naveen Gokul R
SAVEETHA INTERNATIONAL CONFERENCE 2018
SECURED 1ST PLACE
Guided by - Prof PRISCILLA (biochemistry)
Collagen is the main structural protein of the different connective tissues present in animals.
It is mostly found in fibrous tissues, such as tendons and ligaments, and is also abundant in the cornea, cartilage, bones, blood vessels, the gut, and intervertebral discs.
Collagen is the major insoluble fibrous protein found in the extracellular matrix of the skin, together with elastin and hyaluronic acid.
Reverse aging is one of the most important health benefits of collagen use
Ebook: The Insider's Guide on How to Look 10 Years YoungerAviva Pure
This Ebook walks you through step by step on how to make changes to your skin care routine and diet to knock off 10 years of aging. Learn the major factors that cause aging, where your skin is currently at in the aging process and tips from cultures around the world on looking younger.
PREPARATION AND CHARACTERIZATION OF THE POLY HERBAL ANTI-AGEING CREAMAvinash More
To prepare and evaluate the polyherbal cosmetic cream comprising extracts of natural products such as aloe, orange peel extract, punica extract and green tea. Extract of aloe (Aloe vera) and Citrus aurintum(orange peel) Green tea (Camelia sinensis) and pomegranate (Punica granatum)are well known for its medicinal value in Indian traditional system of medicine and in ayurvedic preparation. Present work, was based on extraction of these herbs and formulate poly herbal cosmetic cream.
Collagen comprises of about one third of total protein of our body
Collagen peptide ingestion results in more collagen-producing cells and increases the density of collagen in the skin.
Nizona’s Collagen Peptide has been clinically tested in Japan. Use of hydrolyzed collagen improves skin suppleness, hydration and elasticity which allows its users to look younger and be healthier.
Hydrolyzed collagen contains 20 amino acids, predominantly glycine, proline and hydroxyproline
Hydrolyzed collagen is absorbed as amino acids and small peptides in the blood
Hydrolyzed Japanese collagen reduces wrinkles and results in significant improvement in wrinkle depth, improvement in elasticity and hydration of the skin
Collagen is the most important protein in the bodyKolagen24.pl
NATURAL COLLAGEN AND OTHER EPOCHAL, POLISH BIOTECHNOLOGICAL INVENTIONS PRODUCT CATALOG
Natural Collagen – The Protein of Life Natural Collagen The Protein Of Youth Cosmetic and medical benefits of Natural Collagen Nowadays Supplementation is a must not a luxury
Collagen is a protein commonly found in humans and animals. Collagen is the most important protein in the body, as it constitutes 30% of total human protein, 70% of skin protein, 30-60% of bones, 99% of eye protein and is the main component of connective tissue.
Glissandrin - The Ultimate Anti-Aging Skincare IngredientGlissandra Skincare
This is Part 3 of a 3-part series on the quest by scientists to find effective ways to fight
skin aging. In our previous article, entitled “What have scientists found to fight the
leading cause of skin aging – mitochondrial decay?”, we discussed how Schisandrin B
and (−)Schisandrin B have been proven to be successful in that regard, dramatically
improving the appearance of aging skin.
A study related to this was recently published in the Journal of Cosmetic Dermatology,
the official publication of the International Academy of Cosmetic Dermatology.
“Mitochondria: a new focus as an anti-aging target in skin care”1 confirms the
important role of mitochondrial function in aging and advocates targeting
mitochondria in the development of new products.
Here, we continue to explore the use of Schisandrin B and (−)Schisandrin B in the
revolutionary new ingredient, Glissandrin™, which promises to change the way we
approach skin care.
This presentation shows the aspect of healthy aging. How to age gracefully without any much effort, Slight changes in daily diet and lifestyle can help to slow down aging process.
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03062024_First India Newspaper Jaipur.pdfFIRST INDIA
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role of women and girls in various terror groupssadiakorobi2
Women have three distinct types of involvement: direct involvement in terrorist acts; enabling of others to commit such acts; and facilitating the disengagement of others from violent or extremist groups.
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Find Latest India News and Breaking News these days from India on Politics, Business, Entertainment, Technology, Sports, Lifestyle and Coronavirus News in India and the world over that you can't miss. For real time update Visit our social media handle. Read First India NewsPaper in your morning replace. Visit First India.
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‘वोटर्स विल मस्ट प्रीवेल’ (मतदाताओं को जीतना होगा) अभियान द्वारा जारी हेल्पलाइन नंबर, 4 जून को सुबह 7 बजे से दोपहर 12 बजे तक मतगणना प्रक्रिया में कहीं भी किसी भी तरह के उल्लंघन की रिपोर्ट करने के लिए खुला रहेगा।
In a May 9, 2024 paper, Juri Opitz from the University of Zurich, along with Shira Wein and Nathan Schneider form Georgetown University, discussed the importance of linguistic expertise in natural language processing (NLP) in an era dominated by large language models (LLMs).
The authors explained that while machine translation (MT) previously relied heavily on linguists, the landscape has shifted. “Linguistics is no longer front and center in the way we build NLP systems,” they said. With the emergence of LLMs, which can generate fluent text without the need for specialized modules to handle grammar or semantic coherence, the need for linguistic expertise in NLP is being questioned.
हम आग्रह करते हैं कि जो भी सत्ता में आए, वह संविधान का पालन करे, उसकी रक्षा करे और उसे बनाए रखे।" प्रस्ताव में कुल तीन प्रमुख हस्तक्षेप और उनके तंत्र भी प्रस्तुत किए गए। पहला हस्तक्षेप स्वतंत्र मीडिया को प्रोत्साहित करके, वास्तविकता पर आधारित काउंटर नैरेटिव का निर्माण करके और सत्तारूढ़ सरकार द्वारा नियोजित मनोवैज्ञानिक हेरफेर की रणनीति का मुकाबला करके लोगों द्वारा निर्धारित कथा को बनाए रखना और उस पर कार्यकरना था।
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1. The Effect of a Hydrolyzed Collagen Nutraceutical
on the Cosmetic Appearance of Skin:
Results of a 12 week Clinical Study
by
Heidi Gilchrist, MD
Gilchrist Aesthetic and Medical Dermatology, Encinitas, CA
&
Sarah Ehrlich
Ashieda, LLC, Beverly Hills, CA
Introduction
Collagen is the protein that composes 70-80% of the
dry weight of human skin. The body is capable of
making at least 28 different types of collagen. The
two types mainly relevant to skin health and appear-
ance are collagen type I and collagen type III. These
are the two types that make up most of the collagen
in the second layer of skin, which is known as the
dermis.
At birth, 75% of the collagen in the dermis is type
III and only 25% is type I. Type III collagen is found
in growing children. In adults, those percentages are
reversed and there is mainly type I collagen in the
dermis. The exception is in a healing skin wound,
which reverts back to making type III until a scar has
completely formed.1
Collagen is a structural protein. Fibers of collagen
support the shape of the skin. Collagen formation
and breakdown takes place in the dermis, the thick-
er, firm layer of skin that lies beneath the paper-thin
outer layer, or epidermis, like a mattress lies beneath
a sheet. In youthful skin, collagen is firm, taut, and
abundant, like a new mattress. Just as a foam mattress
over time becomes flatter in places and creased as its
structure breaks down, aging skin begins to sag and
wrinkle when the collagen is diminished and frag-
mented. As skin ages, reactive oxygen species (which
are associated with ultraviolet radiation, environmen-
tal pollution, poor diet, and just normal aging) lead
to increased production of the enzyme collagenase,
which breaks down collagen. Then fibroblasts, the
cells that make collagen, lose their normal stretched
state. The fibroblasts collapse, and then more break-
down enzymes are produced. People in their 80’s
have four times more broken collagen than people in
their 20’s.2 In the elderly, in whom the dermis has lost
two-thirds or more of its youthful thickness through
collagen loss, skin tears and bruises easily.
In recent years, there has been increased scientific
interest2,3,4
in what can be done to slow the break-
down of collagen and build new collagen, even as the
skin ages chronologically. Nutraceuticals are prod-
ucts, often dietary supplements, which have been
demonstrated to have noticeable physiologic effects
or prevent chronic disease. Other studies5,6,7
have
shown that ingestion of hydrolyzed collagen protein
2. supplements can affect moisture content of the skin
(hydration), fine lines, and smoothness by stimulating
collagen production “from the inside out.”
Whole collagen proteins are not easily absorbed in
the gastrointestinal tract. In order to be useful (bio-
available) to the body, the collagen has to be hydro-
lyzed, or broken down into smaller strings of amino
acids that can be digested by enzymes and incorpo-
rated into the body.8
The resulting fragments of col-
lagen protein, called peptides, are easily absorbed and
almost completely absorbed.9
Once in the skin, these collagen peptides may trigger
the body to make more of its own natural collagen
by activating cells called fibroblasts.10
The peptides
also cause the existing collagen to become more or-
ganized, making it stronger and more resilient at the
molecular level11,12
which may mean increased skin
smoothness and suppleness clinically. Finally, colla-
gen is a hygroscopic molecule, which tends to attract
and hold moisture, leading to increased skin hydra-
tion clinically.13
The available research suggests that there is a strong
role for oral supplementation with hydrolyzed colla-
gen in an approach to anti-aging using nutraceuticals.
Methods
Ten otherwise healthy female volunteers aged 29-
60 years, mean age 42 years, consumed a drink
(Beauty Nectar™, Ashieda®, Beverly Hills, Cali-
fornia) containing 3023 mg of hydrolyzed bovine
collagen combined with proprietary amounts of
antioxidants (including vitamin C, resveratrol, kiwi
seed extract, and grape seed extract) and a food
grade ceramide (Oryza Ceramide®-PT, Oryza Oil
& Fat Chemical Co, Ltd, Tokyo, Japan). Subjects
consumed one 50 ml serving three times daily and
were followed over 12 weeks. Clinical photographs
were taken at baseline, 6 weeks, and 12 weeks with
a dermatoscope (ProScope Mobile™, Bodelin
Technologies, Lake Oswego, Oregon). Subjects
were asked to rate eleven specific criteria (Table 1)
about their skin on a scale of 1 to 10 at baseline
and 6-week and 12-week intervals. The same crite-
ria were also subjectively recorded by a board-cer-
tified dermatologist at the same intervals.
Subjective Criteria
Brightness
Deep lines
Elasticity
Fine lines
Firmness
Nourished
Plumpness
Pore size
Skin hydration
Skin smoothness
Suppleness
Collagen Cell
3. Results
Figure 1. Average percent improvement from baseline at 6 weeks and 12 weeks of the subjective criteria as
evaluated by the subject and a dermatologist.
Figure 2. Average improvement on self-assessment (subjective rating 1 to 10) from baseline to 12 weeks of
select criteria.
4. Figure 3. Before and 12 weeks after consuming Beauty Nectar™ 3 times daily for 12 weeks. Dermatoscopic
photographs of the skin of glabella of subject # 1.
Discussion
Anti-aging medicine can include dietary supplemen-
tation, lifestyle changes, herbal products, hormonal
therapies, caloric restriction, and other modalities.
Over the last thirty years, there has been increased
scientific interest in the effects on skin of ingestion
of hydrolyzed collagen peptides. The peptides trig-
ger increased collagen production in the skin, thicker
collagen fibrils, and stronger organization of the col-
lagen.
Vitamin C, or ascorbic acid, is a cofactor in several
enzymatic reactions in the body, including collagen
synthesis. It also serves as an antioxidant to protect
the body by neutralizing free radicals produced by
exposure to ultraviolet radiation, environmental pol-
lutants, and consumption of some processed foods.
Vitamin C has been shown to decrease sunburn cell
formation, thymine dimer formation and p53 pro-
tein expression (both of which signify DNA dam-
age), and expression of matrix metalloproteinase-9
(an enzyme that breaks down collagen).14
Resveratrol is an antioxidant and nutritional supple-
ment. Found in the skin of red grapes as well as in
other fruit, resveratrol has been shown to be anti-in-
flammatory15
and to have anti-cancer activity.16
Grape seed extract contains polyphenols, vitamin
E, and linoleic acid. Polyphenols include flavonoids,
which are potent antioxidants found in red wine. Vi-
tamin E is an antioxidant, and linoleic acid is an ome-
ga-3 fatty acid essential to the body.
Kiwi seed extract contains alpha-linolenic acid, an
omega-6 fatty acid, which is essential to the body.
Ceramides are lipid-based compounds normally
found in human skin and decreased in dry skin with
eczema. Ceramides may help to repair the skin and
replenish the skin barrier.17
Beauty Nectar™ is a hydrolyzed collagen supplement
that also contains vitamin C, resveratrol, grape seed
extract, kiwi seed extract, and ceramides. Our clinical
study found subjective increases in skin hydration,
firmness, smoothness, and suppleness, and decreases
in the appearance of fine lines and pores. Subjects
also reported that their skin looked more nourished,
plump, and bright with improved skin tone. Beauty
Nectar™ is a nutraceutical with a potent role in an
anti-aging regimen.
before after
5. References
1 Bolognia J, Jorrizo JL, Schaffer JV. Dermatology. Philadelphia: Saunders,
2012. Print.
2 Fisher GJ, Varani J, Voorhees JJ. Looking older: fibroblast collapse and ther-
apeutic implications. Arch Dermatol 2008;144(5):666-672.
3 Rittié L, Kang S, Voorhees JJ, et al. Induction of collagen by estradiol: dif-
ference between sun-protected and photodamaged human skin in vivo. Arch
Dermatol 2008;144(9):1129-1140.
4 Orringer JS, Kang S, Johnson TM, et al. Connective tissue remodeling in-
duced by carbon dioxide laser resurfacing of photodamaged human skin. Arch
Dermatol 2004;140(11):1326-1332.
5 Matsumoto H, Ohara H, Ito K, et al. Clinical effects of fish type I col-
lagen hydrolysate on skin properties. ITE Lett Batt New Technol Med
2006;7(3/4):386-390.
6 Morganti P, Randazzo SD, Bruno C. Oral treatment of skin dryness. Cosmet
Toilet 1998;103:77-80.
7 Cosgrove MC, Franco OH, Granger SP, et al. Dietary nutrient intakes
and skin-aging appearance among middle-aged women. Am J Clin Nutr
2007;36:1225-1231.
8 Asghar A, Henrickson RL. Chemical, biochemical, and functional character-
istics of collagen in the food system. Adv Food Res 1982;28:231-372.
9 Oesser S, Adam M, Babel W, et al. Oral administration of 14C labeled colla-
gen hydrosylates leads to an accumulation of radioactivity in cartilage of mice.
J Nutr 1999;129:1891-1895.
10 Postlethwaite AE, Seymour JM, Kang AH. Chemotactic attraction of hu-
man fibroblasts to type I, II, and III collagens and collage-derived peptides.
Proc Acad Sci USA 1978;75:871-875.
11 Minaguchi J, Koyama Y, Hosaka Y, et al. Effects of collagen peptide on
collagen fibrils and glycosaminoglycans in the Achilles tendon. J Nutr Sci Vi-
taminol 2005;51:169-174.
12 Matsuda N, Koyama Y, Hosaka Y, et al. Effects of collagen peptide on
collagen fibrils and glycosaminoglycans in the dermis. J Nutr Sci Vitaminol
2006;52:211-215.
13 Sumida E. The effect of oral ingestion of collagen peptide on skin hydra-
tion and biochemical data in blood. Jour Nutr Food 2004;7(3):45-52.
14 Oresajo C, Stephens T, Hino PD, et al. Protective effects of a topical anti-
oxidant mixture containing vitamin C, ferulic acid, and phloretin against ultra-
violet-induced photodamage in human skin. Jour Cos Dermatol 2008;(7):290-
297.
15 Gentilli M, Mazoit JX, Bouaziz H, et al. Resveratrol decreases hyperalgesia
induced by carrageenan in the rat hind paw. Life Sci 2008; 68 (11):1317–21.
16 Jang M, Cai L, Udeani GO, Slowing KV, et al. Cancer chemopreventive
activity of resveratrol, a natural product derived from grapes. Science 1997;275
(5297):218–20.
17 Coderch L, Lopez O, de la Maza A, et al. Ceramides and skin function. Am
J Clin Dermatol 2003;4(2):107-29.
Conflict of Interest. Dr. Heidi Gilchrist is a consultant for Ashieda, LLC.