The structure of the cell membrane, the phospholipid layer distinguished to the break down of protein and the lipid layer. Their structural components and the molecular basis of it.
Structure and function of plasma membrane 2ICHHA PURAK
The presentation consists of 72 slides,describes following heads
DEFINITION : STRUCTURE OF PLASMA MEMBRANE
COMPONENTS OF PLASMA MEMBRANE ( (BIOCHEMICAL PROPERTIES)
LIPID BILAYER
PROTEINS
CARBOHYDRATES
CHOLESTEROL
MODELS EXPLAINING STRUCTURE OF BIO MEMBRANE
FLUID MOSAIC MODEL
MOBILITY OF MEMBRANE
GLYCOCALYX : GLYCOPROTEINS AND GLYCOLIPIDS
TRANSPORT OF IONS AND MOLECULES ACROSS PLASMA MEMBRANE
FUNCTIONS OF PLASMA MEMBRANE
DIVERSITY OF CELL MEMBRANES
SITE OF ATPASE ION CARRIER CHANNELS AND PUMPS-RECEPTORS
The structure of the cell membrane, the phospholipid layer distinguished to the break down of protein and the lipid layer. Their structural components and the molecular basis of it.
Structure and function of plasma membrane 2ICHHA PURAK
The presentation consists of 72 slides,describes following heads
DEFINITION : STRUCTURE OF PLASMA MEMBRANE
COMPONENTS OF PLASMA MEMBRANE ( (BIOCHEMICAL PROPERTIES)
LIPID BILAYER
PROTEINS
CARBOHYDRATES
CHOLESTEROL
MODELS EXPLAINING STRUCTURE OF BIO MEMBRANE
FLUID MOSAIC MODEL
MOBILITY OF MEMBRANE
GLYCOCALYX : GLYCOPROTEINS AND GLYCOLIPIDS
TRANSPORT OF IONS AND MOLECULES ACROSS PLASMA MEMBRANE
FUNCTIONS OF PLASMA MEMBRANE
DIVERSITY OF CELL MEMBRANES
SITE OF ATPASE ION CARRIER CHANNELS AND PUMPS-RECEPTORS
INTRODUCTION
plasma membrane is also known as cell membrane or cytoplasm membrane.
It is the biological membrane, separates interior of the cell from the outside environment.
Selective permeable to Ions and organic molecules.
Its basic function is to protect the cell from its surroundings.
It consists of the phospholipids bilayer with embedded proteins.
Cell membranes are involved in:cell adhesion, ion conductivity and cell signaling and serve as the attachment surface for several extracellular structures.
Overview of the fundamental roles in Hydropower generation and the components involved in wider Electrical Engineering.
This paper presents the design and construction of hydroelectric dams from the hydrologist’s survey of the valley before construction, all aspects and involved disciplines, fluid dynamics, structural engineering, generation and mains frequency regulation to the very transmission of power through the network in the United Kingdom.
Author: Robbie Edward Sayers
Collaborators and co editors: Charlie Sims and Connor Healey.
(C) 2024 Robbie E. Sayers
INTRODUCTION
plasma membrane is also known as cell membrane or cytoplasm membrane.
It is the biological membrane, separates interior of the cell from the outside environment.
Selective permeable to Ions and organic molecules.
Its basic function is to protect the cell from its surroundings.
It consists of the phospholipids bilayer with embedded proteins.
Cell membranes are involved in:cell adhesion, ion conductivity and cell signaling and serve as the attachment surface for several extracellular structures.
Overview of the fundamental roles in Hydropower generation and the components involved in wider Electrical Engineering.
This paper presents the design and construction of hydroelectric dams from the hydrologist’s survey of the valley before construction, all aspects and involved disciplines, fluid dynamics, structural engineering, generation and mains frequency regulation to the very transmission of power through the network in the United Kingdom.
Author: Robbie Edward Sayers
Collaborators and co editors: Charlie Sims and Connor Healey.
(C) 2024 Robbie E. Sayers
About
Indigenized remote control interface card suitable for MAFI system CCR equipment. Compatible for IDM8000 CCR. Backplane mounted serial and TCP/Ethernet communication module for CCR remote access. IDM 8000 CCR remote control on serial and TCP protocol.
• Remote control: Parallel or serial interface.
• Compatible with MAFI CCR system.
• Compatible with IDM8000 CCR.
• Compatible with Backplane mount serial communication.
• Compatible with commercial and Defence aviation CCR system.
• Remote control system for accessing CCR and allied system over serial or TCP.
• Indigenized local Support/presence in India.
• Easy in configuration using DIP switches.
Technical Specifications
Indigenized remote control interface card suitable for MAFI system CCR equipment. Compatible for IDM8000 CCR. Backplane mounted serial and TCP/Ethernet communication module for CCR remote access. IDM 8000 CCR remote control on serial and TCP protocol.
Key Features
Indigenized remote control interface card suitable for MAFI system CCR equipment. Compatible for IDM8000 CCR. Backplane mounted serial and TCP/Ethernet communication module for CCR remote access. IDM 8000 CCR remote control on serial and TCP protocol.
• Remote control: Parallel or serial interface
• Compatible with MAFI CCR system
• Copatiable with IDM8000 CCR
• Compatible with Backplane mount serial communication.
• Compatible with commercial and Defence aviation CCR system.
• Remote control system for accessing CCR and allied system over serial or TCP.
• Indigenized local Support/presence in India.
Application
• Remote control: Parallel or serial interface.
• Compatible with MAFI CCR system.
• Compatible with IDM8000 CCR.
• Compatible with Backplane mount serial communication.
• Compatible with commercial and Defence aviation CCR system.
• Remote control system for accessing CCR and allied system over serial or TCP.
• Indigenized local Support/presence in India.
• Easy in configuration using DIP switches.
Student information management system project report ii.pdfKamal Acharya
Our project explains about the student management. This project mainly explains the various actions related to student details. This project shows some ease in adding, editing and deleting the student details. It also provides a less time consuming process for viewing, adding, editing and deleting the marks of the students.
Welcome to WIPAC Monthly the magazine brought to you by the LinkedIn Group Water Industry Process Automation & Control.
In this month's edition, along with this month's industry news to celebrate the 13 years since the group was created we have articles including
A case study of the used of Advanced Process Control at the Wastewater Treatment works at Lleida in Spain
A look back on an article on smart wastewater networks in order to see how the industry has measured up in the interim around the adoption of Digital Transformation in the Water Industry.
Final project report on grocery store management system..pdfKamal Acharya
In today’s fast-changing business environment, it’s extremely important to be able to respond to client needs in the most effective and timely manner. If your customers wish to see your business online and have instant access to your products or services.
Online Grocery Store is an e-commerce website, which retails various grocery products. This project allows viewing various products available enables registered users to purchase desired products instantly using Paytm, UPI payment processor (Instant Pay) and also can place order by using Cash on Delivery (Pay Later) option. This project provides an easy access to Administrators and Managers to view orders placed using Pay Later and Instant Pay options.
In order to develop an e-commerce website, a number of Technologies must be studied and understood. These include multi-tiered architecture, server and client-side scripting techniques, implementation technologies, programming language (such as PHP, HTML, CSS, JavaScript) and MySQL relational databases. This is a project with the objective to develop a basic website where a consumer is provided with a shopping cart website and also to know about the technologies used to develop such a website.
This document will discuss each of the underlying technologies to create and implement an e- commerce website.
Hybrid optimization of pumped hydro system and solar- Engr. Abdul-Azeez.pdffxintegritypublishin
Advancements in technology unveil a myriad of electrical and electronic breakthroughs geared towards efficiently harnessing limited resources to meet human energy demands. The optimization of hybrid solar PV panels and pumped hydro energy supply systems plays a pivotal role in utilizing natural resources effectively. This initiative not only benefits humanity but also fosters environmental sustainability. The study investigated the design optimization of these hybrid systems, focusing on understanding solar radiation patterns, identifying geographical influences on solar radiation, formulating a mathematical model for system optimization, and determining the optimal configuration of PV panels and pumped hydro storage. Through a comparative analysis approach and eight weeks of data collection, the study addressed key research questions related to solar radiation patterns and optimal system design. The findings highlighted regions with heightened solar radiation levels, showcasing substantial potential for power generation and emphasizing the system's efficiency. Optimizing system design significantly boosted power generation, promoted renewable energy utilization, and enhanced energy storage capacity. The study underscored the benefits of optimizing hybrid solar PV panels and pumped hydro energy supply systems for sustainable energy usage. Optimizing the design of solar PV panels and pumped hydro energy supply systems as examined across diverse climatic conditions in a developing country, not only enhances power generation but also improves the integration of renewable energy sources and boosts energy storage capacities, particularly beneficial for less economically prosperous regions. Additionally, the study provides valuable insights for advancing energy research in economically viable areas. Recommendations included conducting site-specific assessments, utilizing advanced modeling tools, implementing regular maintenance protocols, and enhancing communication among system components.
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Clase 5_Biomembranas y Bioseñalización (1).pdf
1.
2. Juan Alberto Rebollo Pérez
Docente de planta
jrebollo@utb.edu.co
Biólogo con énfasis en Biotecnología– U de Sucre
Doctoradoen Ciencias Biomédicas – U de Cartagena
3. CLASE 5: Biomembranas
Importancia biomédica. Dinámica de la membrana.
BIOQUÍMICA
Juan A. Rebollo Perez, Ph.D.
Facultad de Ciencias Básicas
2021
4. BIOMEDICAL
IMPORTANCE OF
MEMBRANES
define cell boundaries dynamic, highly fluid structures
lipid bilayer
associated proteins
closed compartments
selective permeabilities
acts as a barrier
differences inside and outside
molecular permeability
specific transporters
ion channels
exchanges material
exocytosis and endocytosis
gap junctions
cell–cell interactions
transmembrane signaling
specialized compartments shape organelles localize enzymes
energy transduction
excitation-response coupling
diseases
Normal cellular function critically depends on normal membranes.
5. MAINTENANCE OF A NORMAL INTRA- & EXTRACELLULARENVIRONMENT IS
FUNDAMENTAL TO LIFE
The Body’s Internal Water Is Compartmentalized
Intracellular Fluid (ICF) Extracellular Fluid (ECF)
Constitutes two-thirds of total body water and
provides a specialized environment for the cell to:
(1) make, store,and utilize energy;
(2) to repair itself;
(3) to replicate;and
(4) to perform cell-specific functions.
Contains about one-third of total body water and
is distributed between the plasma and interstitial
compartments.
The extracellularfluid is a delivery system.
It brings to the cells nutrients, oxygen, various ions
and trace minerals, and a variety of regulatory
molecules that coordinate the functions of widely
separatedcells.
Extracellular fluid removes CO2, waste products,
and toxic or detoxified materials from the
immediate cellular environment.
7. Acyl Groups in the Bilayer Interior Are Ordered to
Varying Degrees
In the transition from the Lo state to the Ld state, the general shape and dimensions of the bilayer
are maintained; what changes is the degree of motion (lateral and rotational) allowed to individual
lipid molecules.
8. Fatty Acid Composition of E. coli Cells Cultured at
Different Temperatures
Cells regulate their lipid composition to achieve a constant membrane
fluidity under various growth conditions
10. Flippases and Floppases
Flippases: Catalyze translocation of the aminophospholipids from the extracellular to the cytosolic leaflet of the
plasma membrane.
Floppases: Move plasma membrane phospholipids and sterols from the cytosolic to the extracellular leaflet and,
like flippases, are ATPdependent
PE, PS
PE, PS
ATP ADP
11. Flippases (left) use ATP to move the aminophospholipids PS and, to a lesser extent, phosphatidylethanolamine (PE), from
the outer leaflet to the inner leaflet of the PM against a concentration gradient. Floppases (middle) use ATP to transport
substrates such as phosphatidylcholine (PC), sphingolipid (SL) and cholesterol against concentration gradients in the
opposite direction. Scramblases (right) are ATP independent and less substrate specific and facilitate the movement of lipids
along concentrationgradients.
12. Lipids and Proteins Diffuse Laterally in the Bilayer
fluorescence recovery after
photobleaching (FRAP)
13. Lipids and Proteins Diffuse Laterally in the Bilayer
Hop diffusion of individual lipid molecules
Restricted motion of the erythrocyte
chloridebicarbonate exchanger and glycophorin
18. The Glucose Transporter of Erythrocytes Mediates Passive Transport
Glucose enters the erythrocyte by passive transport via a specific glucose transporter called GLUT1, at a
rate about 50,000 times greater than it could cross the membrane unassisted.
20. Problems:
1. Properties of Lipids and Lipid Bilayers. Lipid bilayers formed between two aqueous phases have this important
property: they form two-dimensional sheets, the edges of which close on each other and undergo self-sealing to form
vesicles (liposomes).
(a) What properties of lipids are responsible for this property of bilayers? Explain.
(b) What are the consequences of this propertyfor the structure of biological membranes?
21. Problems:
2. Flip-Flop Diffusion The inner leaflet (monolayer)of the human erythrocyte membrane consists predominantly of
phosphatidylethanolamine and phosphatidylserine. The outer leaflet consists predominantly of phosphatidylcholine
and sphingomyelin.Although the phospholipid components of the membrane can diffuse in the fluid bilayer, this
sidedness is preserved at all times. How?
22. Problems:
3. Predicting Membrane Protein Topology from Sequence You have cloned the gene for a human erythrocyte
protein, which you suspect is a membrane protein. From the nucleotide sequence of the gene, you know the amino
acid sequence. From this sequence alone, how would you evaluate the possibility that the protein is an integral
protein?
23. Problems:
4. Use of the Helical Wheel Diagram Ahelical wheel is a two-dimensional representation of a helix, a view along its
central axis. Use the helical wheel diagram shown here to determine the distribution of amino acid residues in a
helical segment with the sequence
–Val–Asp–Arg–Val–Phe–Ser–Asn–Val–Cys–Thr–His–Leu–Lys–Thr–Leu–Gln–Asp–Lys–