In 21 years, technology has advanced tremendously and will likely continue to do so. Health technologies will improve understanding our health through wearable devices and apps linked to read body markers. Communication technologies will advance through brain interfaces and new biometrics like eye gaze. Assistive technologies may include more advanced exoskeletons, mobility aids, and cognitive biofeedback tools. Robots may provide care and knowledge assistance. Challenges include meeting expectations while ensuring security, privacy, affordability and equitable access. Progress will take a team effort to make a difference for all humans.