Genitourinary disease involves disorders of the genital and urinary organs including the kidneys, bladder, and reproductive organs. Chronic renal failure occurs when the kidneys are damaged and can no longer properly remove waste from the blood, affecting over 250,000 Americans annually. Without treatment like dialysis, chronic renal failure leads to total kidney failure or end-stage renal disease which is fatal. A urinary tract infection occurs when bacteria enters the urinary tract anywhere from the urethra to the kidneys. UTI's are especially common in women and while usually easy to treat, they can cause serious kidney infections if left untreated.