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Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 14: Emerging
Infectious Diseases
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter Highlights
• Emerging versus reemerging infectious diseases
• Factors that influence the emergence/reemergence of
infectious diseases
• Recent emerging/reemerging infectious diseases
• Prevention and control of emerging infectious diseases
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Is the following statement True or False?
Factors that influence the emergence or reemergence of
infectious diseases are multiple, complex, and
interrelated.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
True
Rationale: Factors that influence the emergence or
reemergence of infectious diseases are multiple,
complex, and interrelated.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Emerging Infectious Disease
• A newly identified clinically distinct infectious disease, or
the reappearance (or reemergence) of a known infectious
disease after its decline with an incidence that is
increasing in a certain geographic area or in a specific
population.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Factors That Influence Emerging
Infectious Diseases
• Convergence model—model illustrating the interaction of
13 factors that contribute to the emergence of infectious
diseases
• There are following four types of interrelated and
overlapping microbe–human interactions, which can lead
to emerging/reemerging infectious diseases:
– Genetic and biological
– Physical/environmental
– Ecological
– Social, political, and economic
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Is the following statement True or False?
Antigenic shift is the slow and progressive genetic
changes that take place in DNA and RNA as organisms
replicate in multiple hosts, cause changes in influenza
viruses each year.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
False
Rationale: Antigenic drift, the slow and progressive
genetic changes that take place in DNA and RNA as
organisms replicate in multiple hosts, causes changes in
influenza viruses each year. Antigenic shift occurs when
there is a sudden change in the DNA and RNA resulting in
a new strain of the microorganism and people have little
or no acquired immunity.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Microbial Adaptation
• Process by which organisms adjust and change to their
environment
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Microbial Adaptation and Change
• Antigenic drift, the slow and progressive genetic
changes that take place in DNA and RNA as organisms
replicate in multiple hosts, causes changes in influenza
viruses each year.
• Antigenic shift occurs when there is a sudden change in
the DNA and RNA resulting in a new strain of the
microorganism and people have little or no acquired
immunity.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Is the following statement True or False?
Epidemics and pandemics can place long-term demands
on health care systems.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
False
Rationale: Epidemics and pandemics can place sudden
and intense demands on health care systems.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Microbial Adaptation Stages
• Epidemic
• Infection becomes endemic or continuously present in a
geographic area or population of people.
• Symbiosis
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Epidemiologic Triad
• A change in the behavior of humans—the host
• A change in the behavior of the microbes—the agent
• A change in the environment
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Human Susceptibility to Infection
• Herd immunity—type of immunity in which a large
proportion of people in a population are not susceptible
to a communicable disease and the few people who are
susceptible will not be likely to be exposed and contract
the illness
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Microbial Adaptation and Change
• Climate, changing ecosystems, and human behavior
– Ecosystems are groups of interacting living things
that depend on each other for survival.
• Travel, technology, and industry
• Lack of political will and breakdown of public health
infrastructures
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Is the following statement True or False?
Certain zoonotic diseases can be transmitted to humans
through contact with zoo animals.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
False
Rationale: Certain zoonotic diseases can be transmitted
to humans through contact with animals and birds.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Recent Emerging and Reemerging
Infectious Diseases
• Severe acute respiratory syndrome
– Infection control for the prevention SARS-CoV
transmission
• Avian influenza
– Infection Control for the prevention avian influenza
transmission
• H1N1influenza (swine flu) pandemic
• Escherichia coli O157:H7
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Personal Steps to Reduce
Spread of Infection
• Recognize symptoms of the flu and see a health care provider
immediately if you have any of the following:
– A temperature of greater than 100°F
– A cough
– A sore throat
– An underlying condition that increases risk
• Cover your cough or sneeze
• Wash hands often and keep hands away from your face
• Stay home and do not travel if you are ill
• Be prepared for increased illness in your schools and
community
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
West Nile Virus
Community and public health nurses should educate the
public about how to prevent WNV infection:
– Use Food and Drug Administration (FDA)-approved repellents on skin
and clothing for protection from mosquito-borne diseases.
– When weather permits, wear long-sleeved shirts and long pants
outdoors.
– Place mosquito netting over infant carriers when outdoors with
infants.
– Consider staying indoors at dawn, dusk, and early evening, which are
peak mosquito biting times.
– Install or repair window and door screens so that mosquitoes cannot
come indoors
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Lyme Disease
• Epidemiology
• Signs and symptoms
• Prevention
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Tuberculosis
• Epidemiology
• Geographic distribution
• Signs and symptoms
• Latent tuberculosis and human immunodeficiency virus
infection
• Prevention and control of tuberculosis
– Targeted tuberculin testing and treatment of latent
tuberculosis infection
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Directly Observed Therapy
• Health care professionals observe clients to ensure that
they ingest each dose of anti-TB medication, to maximize
the likelihood of completion of therapy.
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Diagnostic and Public Health Evaluation of
Tuberculosis Contacts
• QuantiFERON-TB Gold test
• Multidrug-resistant tuberculosis

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Chapter 14 ppt

  • 1. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 14: Emerging Infectious Diseases
  • 2. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter Highlights • Emerging versus reemerging infectious diseases • Factors that influence the emergence/reemergence of infectious diseases • Recent emerging/reemerging infectious diseases • Prevention and control of emerging infectious diseases
  • 3. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Is the following statement True or False? Factors that influence the emergence or reemergence of infectious diseases are multiple, complex, and interrelated.
  • 4. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer True Rationale: Factors that influence the emergence or reemergence of infectious diseases are multiple, complex, and interrelated.
  • 5. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Emerging Infectious Disease • A newly identified clinically distinct infectious disease, or the reappearance (or reemergence) of a known infectious disease after its decline with an incidence that is increasing in a certain geographic area or in a specific population.
  • 6. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Factors That Influence Emerging Infectious Diseases • Convergence model—model illustrating the interaction of 13 factors that contribute to the emergence of infectious diseases • There are following four types of interrelated and overlapping microbe–human interactions, which can lead to emerging/reemerging infectious diseases: – Genetic and biological – Physical/environmental – Ecological – Social, political, and economic
  • 7. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Is the following statement True or False? Antigenic shift is the slow and progressive genetic changes that take place in DNA and RNA as organisms replicate in multiple hosts, cause changes in influenza viruses each year.
  • 8. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer False Rationale: Antigenic drift, the slow and progressive genetic changes that take place in DNA and RNA as organisms replicate in multiple hosts, causes changes in influenza viruses each year. Antigenic shift occurs when there is a sudden change in the DNA and RNA resulting in a new strain of the microorganism and people have little or no acquired immunity.
  • 9. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Microbial Adaptation • Process by which organisms adjust and change to their environment
  • 10. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Microbial Adaptation and Change • Antigenic drift, the slow and progressive genetic changes that take place in DNA and RNA as organisms replicate in multiple hosts, causes changes in influenza viruses each year. • Antigenic shift occurs when there is a sudden change in the DNA and RNA resulting in a new strain of the microorganism and people have little or no acquired immunity.
  • 11. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Is the following statement True or False? Epidemics and pandemics can place long-term demands on health care systems.
  • 12. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer False Rationale: Epidemics and pandemics can place sudden and intense demands on health care systems.
  • 13. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Microbial Adaptation Stages • Epidemic • Infection becomes endemic or continuously present in a geographic area or population of people. • Symbiosis
  • 14. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Epidemiologic Triad • A change in the behavior of humans—the host • A change in the behavior of the microbes—the agent • A change in the environment
  • 15. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Human Susceptibility to Infection • Herd immunity—type of immunity in which a large proportion of people in a population are not susceptible to a communicable disease and the few people who are susceptible will not be likely to be exposed and contract the illness
  • 16. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Microbial Adaptation and Change • Climate, changing ecosystems, and human behavior – Ecosystems are groups of interacting living things that depend on each other for survival. • Travel, technology, and industry • Lack of political will and breakdown of public health infrastructures
  • 17. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question Is the following statement True or False? Certain zoonotic diseases can be transmitted to humans through contact with zoo animals.
  • 18. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer False Rationale: Certain zoonotic diseases can be transmitted to humans through contact with animals and birds.
  • 19. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Recent Emerging and Reemerging Infectious Diseases • Severe acute respiratory syndrome – Infection control for the prevention SARS-CoV transmission • Avian influenza – Infection Control for the prevention avian influenza transmission • H1N1influenza (swine flu) pandemic • Escherichia coli O157:H7
  • 20. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Personal Steps to Reduce Spread of Infection • Recognize symptoms of the flu and see a health care provider immediately if you have any of the following: – A temperature of greater than 100°F – A cough – A sore throat – An underlying condition that increases risk • Cover your cough or sneeze • Wash hands often and keep hands away from your face • Stay home and do not travel if you are ill • Be prepared for increased illness in your schools and community
  • 21. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins West Nile Virus Community and public health nurses should educate the public about how to prevent WNV infection: – Use Food and Drug Administration (FDA)-approved repellents on skin and clothing for protection from mosquito-borne diseases. – When weather permits, wear long-sleeved shirts and long pants outdoors. – Place mosquito netting over infant carriers when outdoors with infants. – Consider staying indoors at dawn, dusk, and early evening, which are peak mosquito biting times. – Install or repair window and door screens so that mosquitoes cannot come indoors
  • 22. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Lyme Disease • Epidemiology • Signs and symptoms • Prevention
  • 23. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Tuberculosis • Epidemiology • Geographic distribution • Signs and symptoms • Latent tuberculosis and human immunodeficiency virus infection • Prevention and control of tuberculosis – Targeted tuberculin testing and treatment of latent tuberculosis infection
  • 24. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Directly Observed Therapy • Health care professionals observe clients to ensure that they ingest each dose of anti-TB medication, to maximize the likelihood of completion of therapy.
  • 25. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Diagnostic and Public Health Evaluation of Tuberculosis Contacts • QuantiFERON-TB Gold test • Multidrug-resistant tuberculosis