The document summarizes the four primary tissue types found in the human body - epithelial, connective, muscle, and nervous tissue. It provides detailed descriptions of each tissue type, their functions, locations in the body, and key characteristics. For epithelial and connective tissues, it further breaks down the subtypes and provides examples. The document aims to educate on the tissue structures that make up the human body.
5. Tissues - BSc Nursing 1st Semester - by M. Thirumurugan.pptxthiru murugan
Tissues: the group of cells are called tissue. A tissue is an assemble of similar cells that together carry out a specific function. The group of tissues are joined and form organ.
Types or classification:
4 basic tissues:
Epithelial tissue
Connective tissue
Muscular tissue
Nervous tissue
I. EPITHELIAL TISSUE:
Epithelial tissue is made up of epithelial cells.
The cells can be different shapes and can be arranged in a single layer or multiple layers depending on where they are located in body and what kind of functions they have.
All substances that enter or leave an organ must cross the epithelial tissue first.
The epithelium is a type of body tissue that forms the covering on all internal and external surfaces of body, lines body cavities and hollow organs and is the major tissue in glands.
Epithelial tissue has a variety of functions depending on where it’s located in body, including protection, secretion and absorption.
Types of epithelial tissue:
Based on how the cells are arranged:
Simple epithelium
Stratified epithelium
Pseudostratified epithelium
1.simple epithelium: A simple epithelium means that there’s only one layer of cells.
Simple squamous epithelium: This type of epithelium typically lines blood vessels and body cavities and regulates the passage of substances into the underlying tissue.
Simple cuboidal epithelium: This type of epithelium is typically found in glandular (secreting) tissue and kidney tubules.
Simple columnar epithelium: This type of epithelium is often specialized for absorption and usually has apical cilia or microvilli. These cells line in stomach and intestines.
2.stratified epithelium: A stratified epithelium is made up of more than one layer of cells.
Stratified squamous epithelium: This type of epithelium usually has protective functions, including protection against microorganisms from invading underlying tissue and/or protection against water loss. The outer layer of skin (the epidermis) is made of stratified squamous epithelial cells.
Stratified cuboidal epithelium: This type of epithelium is found in the excretory ducts of salivary and sweat glands.
Stratified columnar epithelium: This type of epithelium is not as common and is seen in the mucous membrane (conjunctiva) lining in eyelids, where it’s both protective and mucus-secreting.
3. Pseudostratified:
These are simple columnar epithelial cells whose nuclei appear at different heights, giving the misleading (hence pseudo) impression that the epithelium is stratified when the cells are viewed in cross section.
Pseudostratified epithelium can also possess fine hair-like extensions of their apical (luminal) membrane called cilia.
In this case, the epithelium is described as ciliated pseudostratified epithelium. Ciliated epithelium is found in the airways (nose, bronchi), but is also found in the uterus and fallopian tubes of females, where the cilia propel the ovum to the uterus.
Epithelial cells based on specialized functions
Transitional epith
A tissue may be defined as an aggregate or collection of same type of cells performing the same general functions of the body. For example: Blood, bone, muscle etc.
5. Tissues - BSc Nursing 1st Semester - by M. Thirumurugan.pptxthiru murugan
Tissues: the group of cells are called tissue. A tissue is an assemble of similar cells that together carry out a specific function. The group of tissues are joined and form organ.
Types or classification:
4 basic tissues:
Epithelial tissue
Connective tissue
Muscular tissue
Nervous tissue
I. EPITHELIAL TISSUE:
Epithelial tissue is made up of epithelial cells.
The cells can be different shapes and can be arranged in a single layer or multiple layers depending on where they are located in body and what kind of functions they have.
All substances that enter or leave an organ must cross the epithelial tissue first.
The epithelium is a type of body tissue that forms the covering on all internal and external surfaces of body, lines body cavities and hollow organs and is the major tissue in glands.
Epithelial tissue has a variety of functions depending on where it’s located in body, including protection, secretion and absorption.
Types of epithelial tissue:
Based on how the cells are arranged:
Simple epithelium
Stratified epithelium
Pseudostratified epithelium
1.simple epithelium: A simple epithelium means that there’s only one layer of cells.
Simple squamous epithelium: This type of epithelium typically lines blood vessels and body cavities and regulates the passage of substances into the underlying tissue.
Simple cuboidal epithelium: This type of epithelium is typically found in glandular (secreting) tissue and kidney tubules.
Simple columnar epithelium: This type of epithelium is often specialized for absorption and usually has apical cilia or microvilli. These cells line in stomach and intestines.
2.stratified epithelium: A stratified epithelium is made up of more than one layer of cells.
Stratified squamous epithelium: This type of epithelium usually has protective functions, including protection against microorganisms from invading underlying tissue and/or protection against water loss. The outer layer of skin (the epidermis) is made of stratified squamous epithelial cells.
Stratified cuboidal epithelium: This type of epithelium is found in the excretory ducts of salivary and sweat glands.
Stratified columnar epithelium: This type of epithelium is not as common and is seen in the mucous membrane (conjunctiva) lining in eyelids, where it’s both protective and mucus-secreting.
3. Pseudostratified:
These are simple columnar epithelial cells whose nuclei appear at different heights, giving the misleading (hence pseudo) impression that the epithelium is stratified when the cells are viewed in cross section.
Pseudostratified epithelium can also possess fine hair-like extensions of their apical (luminal) membrane called cilia.
In this case, the epithelium is described as ciliated pseudostratified epithelium. Ciliated epithelium is found in the airways (nose, bronchi), but is also found in the uterus and fallopian tubes of females, where the cilia propel the ovum to the uterus.
Epithelial cells based on specialized functions
Transitional epith
A tissue may be defined as an aggregate or collection of same type of cells performing the same general functions of the body. For example: Blood, bone, muscle etc.
Tissue Definition
Tissues are groups of cells that have a similar structure and act together to perform a specific function. The word tissue comes from a form of an old French verb meaning “to weave”. There are four different types of tissues in animals: connective, muscle, nervous, and epithelial. In plants, tissues are divided into three types: vascular, ground, and epidermal. Groups of tissues make up organs in the body such as the brain and heart.
Types of Animal Tissues
Connective
Connective tissue connects or separates groups of other tissues. It is found in between all the other tissues and organs in the body. Connective tissue is made up of cells and ground substance, which is a gel that surrounds cells. Most connective tissue, except for lymph and blood, also contains fibers, which are long, narrow proteins. Fibers can be collagenous, which bind bones to tissues; elastic, which allow organs like the lungs to move; or reticular, which provide physical support to cells. Connective tissue also allows oxygen to diffuse from blood vessels into cells.
About 1 in 10 people are have a disorder involving connective tissue. Some connective tissue disorders include sarcomas, Marfan syndrome, lupus, and scurvy, which is a Vitamin C deficiency that leads to fragile connective tissue.
Muscle
Muscle tissue comprises all the muscles in the body, and the specialized nature of the tissue is what allows muscles to contract. There are three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle. Skeletal muscle anchors tendons to bones and allows the body to move. Cardiac muscle is found in the heart and contracts to pump blood. Smooth muscle is found in the intestines, where it helps move food through the digestive tract, and it is also found in other organs like blood vessels, the uterus, and the bladder. Skeletal and cardiac muscles are striated; this means that they contain sarcomeres (a unit of muscle tissue) that are arranged in a uniform pattern. Smooth muscle does not have sarcomeres.
Duchenne muscular dystrophy is an example of a muscle tissue disorder. It is an inherited disorder that causes muscles to atrophy over time. The muscles shorten as they atrophy, which can cause scoliosis and immobile joints. Individuals with the disorder are usually male because the gene responsible for it is found on the X chromosome (of which males have only one).
Nervous
Nervous tissue is found in the brain, spinal cord, and peripheral nerves, which are all parts of the nervous system. It is made up of neurons, which are nerve cells, and neuroglia, which are cells that help nerve impulses travel. Nervous tissue is grouped into four types: gray matter and white matter in the brain, and nerves and ganglia in the peripheral nervous system. The main difference between gray and white matter is that axons of the neurons in gray matter are unmyelinated, while white matter is myelinated. Myelin is a white, fatty substance that insulates neurons and
here, you will find out a brief summary about the chapter tissues it is an very interesting chapter in this ppt all the topics have been discussed you can this ppt
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Tissue Definition
Tissues are groups of cells that have a similar structure and act together to perform a specific function. The word tissue comes from a form of an old French verb meaning “to weave”. There are four different types of tissues in animals: connective, muscle, nervous, and epithelial. In plants, tissues are divided into three types: vascular, ground, and epidermal. Groups of tissues make up organs in the body such as the brain and heart.
Types of Animal Tissues
Connective
Connective tissue connects or separates groups of other tissues. It is found in between all the other tissues and organs in the body. Connective tissue is made up of cells and ground substance, which is a gel that surrounds cells. Most connective tissue, except for lymph and blood, also contains fibers, which are long, narrow proteins. Fibers can be collagenous, which bind bones to tissues; elastic, which allow organs like the lungs to move; or reticular, which provide physical support to cells. Connective tissue also allows oxygen to diffuse from blood vessels into cells.
About 1 in 10 people are have a disorder involving connective tissue. Some connective tissue disorders include sarcomas, Marfan syndrome, lupus, and scurvy, which is a Vitamin C deficiency that leads to fragile connective tissue.
Muscle
Muscle tissue comprises all the muscles in the body, and the specialized nature of the tissue is what allows muscles to contract. There are three types of muscle tissue: skeletal muscle, cardiac muscle, and smooth muscle. Skeletal muscle anchors tendons to bones and allows the body to move. Cardiac muscle is found in the heart and contracts to pump blood. Smooth muscle is found in the intestines, where it helps move food through the digestive tract, and it is also found in other organs like blood vessels, the uterus, and the bladder. Skeletal and cardiac muscles are striated; this means that they contain sarcomeres (a unit of muscle tissue) that are arranged in a uniform pattern. Smooth muscle does not have sarcomeres.
Duchenne muscular dystrophy is an example of a muscle tissue disorder. It is an inherited disorder that causes muscles to atrophy over time. The muscles shorten as they atrophy, which can cause scoliosis and immobile joints. Individuals with the disorder are usually male because the gene responsible for it is found on the X chromosome (of which males have only one).
Nervous
Nervous tissue is found in the brain, spinal cord, and peripheral nerves, which are all parts of the nervous system. It is made up of neurons, which are nerve cells, and neuroglia, which are cells that help nerve impulses travel. Nervous tissue is grouped into four types: gray matter and white matter in the brain, and nerves and ganglia in the peripheral nervous system. The main difference between gray and white matter is that axons of the neurons in gray matter are unmyelinated, while white matter is myelinated. Myelin is a white, fatty substance that insulates neurons and
here, you will find out a brief summary about the chapter tissues it is an very interesting chapter in this ppt all the topics have been discussed you can this ppt
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Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
2. Tissues
• Tissues are composed of cells similar in structure and specialized
to perform a specific function for the body.
• The human body is made of four general types of tissues.
– Epithelial tissues – for lining body cavities, covering internal
organs and large surfaces.
– Connective tissues – for supporting and linking tissues or
organs together; some are specialized to provide protection, to
store fat, and even to provide circulatory function in the
cardiovascular system.
– Muscle tissues – for providing contraction and relaxation in
the body surfaces, in the heart chambers , and in hollow organs
such as blood vessels and the digestive tract.
– Nerve tissue – for generating and transmitting electrical
signals (nerve impulses ) in the brain, spinal cord, and nerves.
ebneshahidi
3. Epithelial tissues (Epithelium)
• 1. Covering of body surfaces and internal organs, and lining of
body cavities.
• 2. Major tissue component of glands.
• 3. Always has a free surface (exposed to an open space) and a
basement membrane (usually anchored to a connective tissue).
• 4. Lacks blood vessels , so nourishment comes from the underlying
connective tissue by diffusion movement.
• 5. Other unique characteristics:
• a. Reproduce rapidly.
• b. Cells in epithelial tissues are often attached to one another by
desmosomes which allow the tissue to serve as an excellent
protective layer.
ebneshahidi
4. • c. The name is
derived from the
number of layer of
cells ("simple" means
a single layer while
"stratified " means
multiple layers ) and
the shape of cells
("squamous" means
flattened , "cuboidal"
means cube – shaped
,and "columnar"
means elongated ).
ebneshahidi
5. 1. Simple squamous epithelium
– a single layer of thin , flattened cells.
– Found in areas where diffusion or filtration occurs.
– Examples – air sacs of lungs , kidney tubules , and capillary wall.
– Simple squamous epithelium lining blood vessels and heart is
called endothelium.
ebneshahidi
6. 2. Simple cuboidal epithelium
– a single layer of cube – shaped cells .
– Found in areas where secretion or absorption occurs.
– Examples – kidney tubules, and ducts of glands
ebneshahidi
7. 3. Simple columnar epithelium
– a single layer of elongated cells.
– designed for protection, secretion, or absorption.
– examples – lining of uterus and small intestine.
– some columnar cells have finger – like projections called
microvilli which are extension of the cell membrane for
increasing the surface area in absorption.
ebneshahidi
8. 4. Pseudostratified columnar epithelium
• a single layer of columnar cells that appears to be multiple – layered
because of its multiple – layered nuclei .
• the cells have hair – like protein structure called cilia on the cell
membrane to trap and expel foreign particles or bacteria, or they may
be used to propel the egg cell in the uterine tubes.
ebneshahidi
9. 5. Stratified squamous epithelium
• many layers of flattened cells .
• cells at the bottom layers are the youngest and cuboidal – shaped, and
will become flattened as they move upward to higher layers.
• Forms the epidermis (top skin layer), lining of oral cavity, throat, and
vagina.
ebneshahidi
10. 6. Stratified cuboidal epithelium
• 2-3 layers , cube shaped cells.
• Function: protection.
• Location : lining of larger ducts of sweat glands , salivary
gourds and the pancreas.
7. Stratified columnar epithelium
• Top layer of elongated cells lower layers of cube-shaped cells .
• Location : use deferens , port of the urethra and pharynx.
• Function : protection, secretion.
ebneshahidi
11. 7. Transitional Epithelium
• many layers of cube – shaped and elongated cells
• function : Dispensability, protection
• location : inner lining of urinary bladder and lining of waters and
urethra .
ebneshahidi
12. 8. Glandular epithelium
–specialized to produce and secrete chemical
substances into ducts or body fluids .
–made of cuboidal or columnar cells.
–Exocrine glands use ducts to secrete their
products into an open space (e.g. sweat glands ,
oil glands , salivary glands, and tear glands).
–Endocrine glands secrete their products
(hormones) directly into blood or body fluids (e.g.
all hormonal glands are endocrine glands).
ebneshahidi
13. Types of exocrine glands
• Merocrine glands – A fluid product released
through the cell membrane by exocytosis . ex:
salivary glands , pancreatic glands , sweat
glands.
• Aporcine glands – cellular product and
portions of the free ends of cells pinch off
during secretion. ex : mammary glands .
• Holocrine glands – Entire cell with secretory
products rupture Ex : sebaceous glands of skin.
ebneshahidi
15. Multicellular exocrine glands
• Simple – single unbranched duct
• Compound – branched duct
• Multicellular exocrine glands can be:
a) Tubular – secretory cells form a tube.
b) Alveolar – secretory cells form a sac.
c) tubuloalveolar
ebneshahidi
17. Unicellular Exocrine Glands
• Unicellular exocrine glands;
• Single cells
• Have no ducts
• Produce mucin: forms mucus that protect and
lubricate surfaces.
ebneshahidi
18. Connective tissue
• Most abundant of the primary tissues by weight.
• Function :
1) Binding and Support
2) Protection
3) Insulation
4) Transportation (blood)
• origin : All C.T. arise from mesenchyme derived from embryonic
mesoderm germ layer.
• Have matrix : fills the space between cells.
• Fibers ( 3 types).
• ground substance (matrix): fills the space between cells.
• cells
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20. • Contain a noncellular matrix which is made of protein fibers and
ground substances .
• Contain "resident cells" and “wandering cells”
• Fibers of connective tissue:
1. Collagen fibers – provide tensile strength (thickest fibers).
2. Elastic fibers – provide stretch.
3. Reticular fibers – provide a network to support blood vessels and
support soft tissue of organs.
• Cells of connective tissue :
1. Fibroblast – form connective tissue proper.
2. Chondroblast - cartilage forming.
3. Osteoblast – bone forming.
4. Hemocytoblast – blood forming.
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22. • Other cells in connective tissue :
1. White blood cells (immunity)
2. Plasma cells (antibody producing)
3. Mast cells (detect bacteria and fungi and
initiate local inflammatory -response
against them)
3. Macrophages (immunity) – engulf and
dispose bacteria , and other un wanted
substances .
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23. Loose Connective Tissue
• Loose connective tissue:
(areola connective tissue)
• Forms delicate , thin
membranes throughout the
body.
• Binds the skin to
underlying organs , fills
spaces between muscles
and other organs .
• Consists of cells called
fibroblasts , and both
collagen us and elastic
fibers in the matrix.
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25. Adipose Tissue
Modified from loose
connective.
Specialized to store fat
at the center of ring –
shaped cells called
adipocytes.
Serves as protective
cushion for joints and
organs , as heat
insulator beneath the
skin , and to store
energy .
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26. Dense Regular Connective Tissue
• Dense regular
connective tissue:
• forms tendons, and
ligaments.
• Poor blood supply.
• Contains closely
packed bundles of
collagen fibers .
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27. Dense irregular Connective tissue
– Arranged irregularly.
– Bundles are much thicker.
– Forms Dermis (inner skin layer).
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28. Blood
• Blood: most atypical
connective tissue. it is
composed of cells that
are suspended in a
fluid intercellular
matrix called blood
plasma.
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29. Cartilage
• Support body parts , provide frameworks and
attachments , protect underlying tissues, and form a
model for developing bones.
• Contain a rich matrix made of protein fibers and
protein – rich ground substances.
• Consist of cells called chondrocytes which are
found in cavities called lacunae. The cells obtain
their nutrients by diffusion from the matrix, since
cartilage is the only C.T. that is avascular.
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30. Hyaline cartilage
• Hyaline cartilage
• contains fine collagen
us fibers in the matrix.
• The most common
type of cartilage.
• Found in the ends of
bones at the joints ,
and surrounding the
trachea.
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31. Elastic Cartilage
• Contains elastic
fibers in the matrix.
• Provides framework
for the external ear
and the larynx.
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32. Fibrocartilage
• contains thick
collagen us fibers in
the matrix.
• Serves as shock
absorber in the inter
vertebral disks, and
between bones in the
knee and pelvis.
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33. Bone
• Bone tissue (or osseous tissue):
• The most rigid connective tissue because of the calcium
deposited in the matrix.
• Provides internal support for the body, protects vital
organs , and serves as attachment for most skeletal
muscles.
• Consists of many functional units called ostenos . Each
osteen is composed of cells called osteocytes (surrounded
by lacunae) forming concentric circles around the
osteonic canal.
• Blood vessels in the isotonic canal allow nutrients to
diffuse into fine channels called canaliculi for
distributing the nourishment to all osteocytes .
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35. Muscle tissue
• Consist of muscle cells called muscle fibers
which contain long protein filaments called
myofibrils that allow the cells to contract and
produce body movements .
• Function: movement
• Location: attached to bones in the walls of
hollow internal organs
• Characteristics: contractile
• Types: 3 types
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36. Skeletal Muscle
• Skeletal muscle (striated muscle)
• under voluntary control , multinucleated, striated, and can
contract with powerful force.
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37. Cardiac Muscle
• mostly under involuntary control, uninucleated, cross-striated,
form interconnected branching, contain specialized intercellular
junctions called intercalated disk, and can contract continuously
and rapidly .
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38. Smooth muscle
• Smooth muscle (or involuntary, visceral muscle)
• under involuntary control, uninucleated, not striated, and
contracts with less force but longer duration.
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39. Nervous Tissue
• found in the brain , spinal cord , and nerves.
• consists of cells called neurons that are
sensitive to changes (stimuli) in the
environment and within the body , resulting in
generating and transmitting nerve impulses
through their nerve fibers.
• 2 types of nerve fibers
• axon – only 1 per neuron ; transmits impulses
away from the cell.
• Dendrite – thousands per neuron ; transmits
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41. Epithelial membranes
• It is a continuous multicellular sheet composed of at least 2
layer
• epithelium
• underlying layer of connective tissue
• 1. Cutaneous membranes:
• The coetaneous membrane is the skin which has :
• keratinized squamous epithelium known as epidermis.
• underlying layer of dense irregulars connective tissue or
dermis.
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42. Mucous membranes:
line body cavity
underlying layer of loose connective tissue called lamina propria.
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43. • serous membranes:
• moist membrane found in ventral body cavity. it has a
parietal layer that lines the cavity wall and a visceral
layer that covers the outer surface of organs within the
cavity .
• Between the above layers is a thin clear serous fluid that
act as a lubricant .
• The serous lining the thoracic cavity and covering lung is
the pleura .
• The serous enclosing the heart is the pericardium .
• The serous enclosing the abdomen pelvic cavity and
viscera are the peritoneums.
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45. • synovial membrane
– forms inner lining of joint cavities at the synovial
joints (freely movable joints)
– made of a layer of cuboidal epithelium over a layer
of connective tissue .
– secretes synovial fluid to lubricate the synovial
joints .
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46. Developmental aspects of tissue
• There are 3 primary germ cell embryonically.
• 1) Ectoderm
• 2) Mesoderm
• 3) Endoderm
• These germ cells specialize to form the 4 primary tissues from
which all body organs are derived .
• Epithelial tissues are formed by all 3 germ layers .
• Mucosal epithelium is from endoderm
• Endothelium isfrom mesoderm
• Epidermis is from ectoderm
• Muscle and connective tissue are derived from mesoderm
• nervous tissue is form ectoderm
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48. Clinical Terms
• Adenoma: tumor of glandular Epithelium.
• Carcinoma: cancer arising in an epithelium.
• Sarcoma: cancer arising from mesenchyme –
derived tissue, that is in connective tissue and
muscle.
• Lesion: an injury or wound.
• Pathology: study of changes in organ and
tissues produced by disease.
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