CBGW Brian Van Doormaal
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This is a presentation from the Canadian Bovine Genomics Workshop held in Calgary, Alberta on Sept.14, 2009. The workshop was the first step in developing a national bovine genomics strategy for Canada.
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CBGW Brian Van Doormaal
- 1. ALMA Alberta Livestock & Meat Agency Ltd. Canadian Bovine Genomics Workshop September 14, 2009 Calgary, Alberta
- 2. Genomic Applications in Dairy Cattle: Now and in the Future Brian Van Doormaal General Manager Canadian Dairy Network (CDN)
- 5. DNA Sequencing & SNPs SNP (“snip”) = S ingle N ucleotide P olymorphism (one) (molecule) (changes form)
- 12. Incorporating DGVs into New Official Genetic Evaluations New Genetic Evaluation Current Official Evaluation Pedigree Performance PA EBV MACE GPA GEBV GMACE Direct Genomic Value (DGV) DNA Genotypes
- 13. Gains in Published REL - LPI by Sub-Group - Sub-Group Average Reliability (%) Blending Weight in DGV Traditional Genomics Gain Young Bulls and Heifers (2007-2009) 34 54 19 61% Younger Cows in 1 st or 2 nd Lactation 52 62 10 54% Foreign Cows with MACE in Canada 42 57 15 58% 1 st Crop Proven Sires in Canada 85 88 3 51% Foreign Sires with MACE in Canada 69 77 7 53%
- 14. Genomic Evaluation Details www.cdn.ca
- 23. DNA Ear Tags
Editor's Notes
- 0 = homozygous for first allele ; 1 = heterozygous ; 2 = homozygous for second allele This shows 864 alleles. (out of over 2000) If we were to show all of the base pairs for the first chromosome, I would have to show you 1 slide, per second for over 3 days. Vast portions of the chromosome are homozygous, and not interesting,, ie all animals have the same DNA sequence. Looking at a foundation bull such as elevation shows many alleles are heterozygous. Pedigree analysis by Holstein Association 956 bulls in the April 2008 sire guide red book had 15.2% genes in common with Elevation. Seven generations back, showed on average Elevation appearing 3.5 times in these bulls pedigrees. 8 generations 2 times. Nine generations showed Elevation an average of once per bull. So what does this really mean?