MediaMosa en EDIT: Online Onderwijs Makkelijk GemaaktGeert Wissink
ED*IT is sinds september 2009 het meest multimediale onderwijsplatform van Nederland. Leerlingen en leraren uit het basis en middelbaar onderwijs hebben met ED*IT toegang tot tienduizenden originele video’s, film- en geluidsfragmenten, artikelen en foto’s uit het Nederlands cultureel erfgoed. ED*IT beidt de mogelijkheid om zelf materiaal up te loaden en deze met geavanceerde verwerkingsapplicaties om te zetten in online presentaties, montages, dossiers en tijdlijnen. Aan de achterkant verzorgt Mediamosa het streamen, de metadata en transcoding. In deze presentatie gaan we dieper in op de koppeling tussen ED*IT en MediaMosa en welke lessen zijn te trekken uit het afgelopen jaar.
MediaMosa en EDIT: Online Onderwijs Makkelijk GemaaktGeert Wissink
ED*IT is sinds september 2009 het meest multimediale onderwijsplatform van Nederland. Leerlingen en leraren uit het basis en middelbaar onderwijs hebben met ED*IT toegang tot tienduizenden originele video’s, film- en geluidsfragmenten, artikelen en foto’s uit het Nederlands cultureel erfgoed. ED*IT beidt de mogelijkheid om zelf materiaal up te loaden en deze met geavanceerde verwerkingsapplicaties om te zetten in online presentaties, montages, dossiers en tijdlijnen. Aan de achterkant verzorgt Mediamosa het streamen, de metadata en transcoding. In deze presentatie gaan we dieper in op de koppeling tussen ED*IT en MediaMosa en welke lessen zijn te trekken uit het afgelopen jaar.
A collection of images of different landscapes in Scotland. This will probably always be a work in progress but my intention is to examine the families of rocks which make up the different terranes in Scotland and illustrate the characteristics of the resultant landscapes. This is the introduction. Teachers can pick and mix the slides to suit themselves or if you are an armchair geographer / geologist, then you can just put it to music and enjoy.
The Responsive Grid & You: Extending Your WordPress Site Across Multiple Dev...Jeremy Fuksa
Presented to WordCamp KC 2011.
If you are a web designer of any type, you're interested in making sure your designs are faithful AND useful to the widest audience possible. This has been true for years. But now, your audience has widened to mobile users and also users on HDTVs. How do you accommodate them? Simple: Responsive Web Design.
This talk shows how to use some of the open source responsive CSS frameworks to make sites that are fluid and adaptable to a wide range of devices.
A collection of images of different landscapes in Scotland. This will probably always be a work in progress but my intention is to examine the families of rocks which make up the different terranes in Scotland and illustrate the characteristics of the resultant landscapes. This is the introduction. Teachers can pick and mix the slides to suit themselves or if you are an armchair geographer / geologist, then you can just put it to music and enjoy.
The Responsive Grid & You: Extending Your WordPress Site Across Multiple Dev...Jeremy Fuksa
Presented to WordCamp KC 2011.
If you are a web designer of any type, you're interested in making sure your designs are faithful AND useful to the widest audience possible. This has been true for years. But now, your audience has widened to mobile users and also users on HDTVs. How do you accommodate them? Simple: Responsive Web Design.
This talk shows how to use some of the open source responsive CSS frameworks to make sites that are fluid and adaptable to a wide range of devices.
Perioperative evaluation of difficult clinical scenarios which prompted to delay of surgery:
- Undiagnosed aortic regurgitation
- Pleural effusion with suspected TB
A case presentation and discussion of TB Meningitis presented in a Tertiary Care Hospital ER. Includes presenting complaints, work-up, diagnosis and relevant case discussion.
Presented an in-service on the pathophysiology and differential diagnosis of cauda equina syndrome to Arcadia University's 2nd year Doctor of Physical Therapy students.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
How to Give Better Lectures: Some Tips for Doctors
Cath conference5jan2015
1. CATH CONFERENCE 5FEB2015
FRANK MEISSNER, MD, RDMS, RDCS
FACP, FACC, FCCP, FASNC, CPHIMS, CCDS
2nd Law of Cardiology:
A Good Angiogram
Trumps A Room Full of
Speculating Cardiologists
2. XMAS EVE CHEST PAIN ED VISIT
SERIAL TROPONIN 24DEC@20:19 0.02 NG/DL;
24DEC@22:01 0.03 NG/DL; 25DEC04:03 0.41 NG/DL
65 y/o Hispanic Female No Previous Hx/o Chest Pain
CRF: HTN, Lipids, ex-13 yr smoker , postmenopausal
Transient (30 mins) Non-exertional Central Burning Pain,
Moderate Intensity, Mild Associated Dyspnea
No Hx/o GERD, Mild Bronchitic symptoms X 1wk
Mildly Obese, Soft S4, Mild Bronchial Breath Sounds
No Diagnostic Chest Xray or EKG Findings
No Chest Pain on Ward - Last Pain in ED
10. RECURRENT SYNCOPE
30 Y/O REPAIRING HIS ROOF JULY 2014 FELL 14’
NECK & BACK PAIN POST TRAUMA SEQUELA
PREMONITION ABSENT SYNCOPE NOT CLEARLY
POSTURAL
NO CHEST PAIN, DYSPNEA, POUNDING PALPITATIONS
AFTER MULTIPLE SERIAL EVALUATIONS, HE
REPORTEED THAT SYNCOPE OR VISUAL BLACK OUT
WAS ASSOCIATED APPROX 50% OF THE TIME WITH
NECK TURNING (KEPT SYMPTOM DIARY)
NEGATIVE ECHO, NUC-TMT, CAROTID DOPPLER U/S,
CAROTID CTA, LEFT HEART CATH, TILT TABLE
TESTING, NO ARRHYTHMIA BY PROLONGED TELE
MONITORING
MRI CSPINE => CERVICAL MYELOPATHY &
CERVICAL 5-6 INSTABILITY
13. BOW HUNTER’S SYNCOPE
SORENSON BF: BOW HUNTER’S STROKE. NEUROSURGERY 2:
259-261, 1978 - 1ST DESCRIPTION PATIENT DEVELOPED
HEMIPARESIS AND CONTRALATERAL SENSORY CHANGES
DURING ARCHERY PRACTICE.
BOW HUNTER’S SYNCOPE RARE FORM OF VBI PRESENTS AS
DIZZINESS, VERTIGO, SYNCOPE, NAUSEA, OR SENSORIMOTOR
DISTURBANCE DUE TO STENOSIS OR OCCLUSION OF THE
VERTEBRAL ARTERY FOLLOWING HEAD ROTATION ABOUT THE
CRANIO-CERVICAL AXIS
USUALLY OCCLUSION OCCURS AT THE C1 TO C2 LEVELS, BUT
LESIONS AT MULTIPLE LEVELS IN THE CERVICAL SPINE HAVE
BEEN REPORTED
CONCURRENT HYPOPLASTIC VA OR POOR CIRCLE OF WILLIS
COLLATERALIZATION CONTRIBUTING FACTOR TO SYMPTOM
PRODUCTION
CONCURRENT HYPOPLASTIC VA OR POOR CIRCLE OF WILLIS
COLLATERALIZATION CONTRIBUTING FACTOR TO SYMPTOM
PRODUCTION
14. 11/11/2014 - DR VELIMIROVIC
C5-6 DECOMPRESSIVE LAMINECTOMY + MEDIAL FACETECTOMY
AND PARTIAL BILATERAL FORAMINOTOMY
C5-6 POSTEROLATERAL ARTHRODESIS & SCREW FIXATION OF
C5-6
OPEN REDUCTION OF CERVICAL 5-6 INSTABILITY AND
DISLOCATION
OPEN REDUCTION OF CERVICAL 5-6 INSTABILITY AND
DISLOCATION
12/26/2014 - DR VELIMIROVIC
SPINAL ANGIOGRAM + CEREBRAL ANGIOGRAM WITH DYNAMIC
CERVICAL ANGIOGRAPHY — NO EVIDENCE OF VERTEBRAL
ARTERY OCCLUSION DURING PROVOCATIVE MANEUVERS
TO DATE NO FURTHER
SYNCOPE
15. DON’T TURN YOUR HEAD
HELTON, TJ & BAVRY AA. CIRCULATION.
2009, 120:E162.
IMAGES IN CARDIOVASCULAR MEDICINE
1st Law of Cardiology:
We Are All One Heart Beat
From Eternity.