A 37-year-old female patient presented with fever, body pains, and vomiting for 3 days. Tests showed leukopenia, thrombocytopenia, and positive dengue antibodies. She was diagnosed with dengue fever and treated with medications including paracetamol, pantoprazole, carica papaya leaf, ondansetron, and cefpodoxime over 6 days. Her platelet count and hematocrit were monitored daily. Oral rehydration and dietary advice were also provided.

1. B.LAKSHMI
PHARM-D

2.  NAME : Narayanamma
 AGE: 37yrs
 GENDER: Female
 DOA: 07-9-19
 DOD: 13-9-19

3.  c/o fever since 3 days
 Associated with body pains
 Personal history : mixed diet

4. 9-9-19 10-9-
19
11-9-19 12-9-19
BP 110/70 120/70 110/70 110/70
PR 80b/m 82b/m 82b/m 86b/m
TEMP 98.7 N N N

5. TEST ABNORMAL NORMAL
8-9-19 9-9-19 11-9-19
HB 12.9gm/dl 14.6 12.5 13-18gm/dl
ESR 25mm/hr 0-5mm/hr
NEUTROPHILS 39 39 32 40-70%
LYMPHOCYTES 46 46 57 20-45%
PLATELETS 36000 36000 31000 1.5-
4Laks/cum
MICROBIOLOGY
DENGUE ANTIBODIES=+VE
HEMATOLOGY
IMP: Normocytic-normochromic blood picture with
leukopenia and thrombocytopenia

6. DENGUE FEVER

7. DEFINATION:
Dengue (DENG-gey) fever is a mosquito-borne disease that occurs in tropical
and subtropical areas of the world. Mild dengue fever causes a high fever, rash,
and muscle and joint pain. A severe form of dengue fever, also called dengue
hemorrhagic fever, can cause severe bleeding, a sudden drop in blood pressure
(shock) and death. caused by a family of viruses transmitted by
infected mosquitoes.
SIGNS AND SYMPTOMS
 High fever and severe headache,
 joint pain,
 muscle and bone pain,
 rash,
 and mild bleeding.

8.  dengue fever can damage the lungs, liver or
heart.
 Blood pressure can drop to dangerous levels,
causing shock and, in some cases, death

11.  Acetaminophen (Tylenol, others) can alleviate
pain and reduce fever.
 Avoid pain relievers that can increase bleeding
complications — such as aspirin, ibuprofen
(Advil, Motrin IB, others) and naproxen sodium
(Aleve, others).
severe dengue fever need:
 Supportive care in a hospital
 Intravenous (IV) fluid and electrolyte replacement
 Blood pressure monitoring
 Transfusion to replace blood loss

12.  Wear long-sleeve shirts and long pants.
 Treat clothes with repellents like permethrin.
 Use mosquito repellent like DEET
 Consider using mosquito net
 Windows and doors screens are closed to
avoid allowing mosquitoes
 Avoid areas with standing water.

13. A female patient was admitted in vishwa bharathi hospital with
a chief complaints of:
c/o fever & vomithing since 3 days
 Associated with body pains
 Personal history : mixed diet

14. TEST ABNORMAL NORMAL
8-9-19 9-9-19 11-9-19
HB 12.9gm/dl 14.6 12.5 13-18gm/dl
ESR 25mm/hr 0-5mm/hr
NEUTROPHILS 39 39 32 40-70%
LYMPHOCYTES 46 46 57 20-45%
PLATELETS 36000 36000 31000 1.5-
4Laks/cum
MICROBIOLOGY
DENGUE ANTIBODIES=+VE
HEMATOLOGY
IMP: Normocytic-normochromic blood picture with
leukopenia and thrombocytopenia

15. DENGUE FEVER

16. S.N
O
DRUGS GENERIC
NAME
DOSE ROA FREQU
ENCY
1st
da
y
2nd
day
3rd
da
y
4th
da
y
5th
da
y
6th
day
1 DOLO Paracetamol 650mg Oral TID    
2 PANTOP Pantoprazole 40mg Oral OD    
3 T.caripil Carica
papaya
leaf
1.1g
m
Oral TID   
4 VOMISET Ondanserton 2ml Oral BD    sos sos
5 t.capode
m
cefpodoxi
me
200m
g
oral BD   

17.  T.B-complex –od
 T.patap-od 40mg
 T.dolo-sos 650mg

18.  cefpodoxime+ pantoprazole=increase gastric
pH may reduce the oral bioavailability of
cefpodoxime.
Management:
Avoid Co administration with H2-receptors
antagonists, proton pump inhibitors. An
alternative antibiotic may be considered.

19.  Patients with dengue fever should monitor
platelet count and hematocrit value daily.
 Monitor patient temperature daily.

20.  Oral rehydration therapy recommended for Patients
with moderate dehydration caused by high fever and
vomithing
 Avoid spicy and fatty food
 Include leafy vegetables in diet
 Keep your hands and surrounding clean