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BUERGER’S
DISEASE
THROMBOANGITIS OBLITRANS
(TAO)
Buerger’s disease is a segmental ,progressive ,occlusive ,inflammatory disease
of small and medium sized vessels with superficial thrombophlebitis often
may present as Raynaud’s phenomenon with micro abscesses, along with
neutrophil and gaint cell infiltration , with skip lesions.
More common in lower limbs than upper limbs
INCIDENCE
▶ Very commonly seen in young
and middle aged males (20 – 40 yrs)
▶ Seen only in smokers and
tobacco users
▶ Rarely can occur in females
smokers
▶ Common in jewish people
RISK FACTORS
▶ Smoking is prime risk factor >40 pack years
▶ hormonal influence ,familial factors
▶ Hypersensitivity to cigarette ,
▶ Altered autonomic functions
▶ Lower socioeconomic group ,
▶ Recurrent minor feet injuries
▶ Poor hygiene
SHIANOYA’S CRITERIA OF BUERGER’S DISEASE
▶ Male Tobacco user
▶ Disease onset before 45 yrs
▶ Distal extremity involved first with out embolic or atherosclerotic features
▶ Absence of diabetes mellitus or hyperlipidemia
▶ With or without thrombophlebitis
CLASSIFICATION OF BUERGER’S DISEASE
▶ Type 1 :
upper limb TAO
▶ Type 2 :
involving legs & feet
–
crural/infrapopliteal
▶ Type 3 :
femoropopliteal
▶ Type 4 :
aortoiliofemoral
▶ Type 5 :
generalised
CLINICAL FEATURES
▶ Common in male smokers between 20-40 yrs of age group –
smoker’s disease
▶ Intermittent claudication pain in foot and calf
▶ Recurrent migratory superficial thrombophlebitis
Claudication
pain
Rest pain
Ulceration and
gangrene
CLINICAL FEATURES
▶ Absence / feeble pulsations distal to proximal ,dorsalis
pedis ,posterior tibial , popliteal ,femoral arteries in lower limbs
▶ It may also present as Raynaud’s phenomenon
INVESTIGATIONS
▶ Blood sugar levels – DIABETES MELLITUS
▶ Lipid profile- any dyslipidemia
▶ Decreasesd Hb levels – delayed healing
▶ WBC count - infection
• CORKSCREW APPEARANCE OF
• COLLATERALS DUE TO
DILATION OF VASA
VASORUM
Arterial flow , flow rate, velocity,
stenosis, block.
TRANSFEMORAL RETROGRADE
ANGIOGRAM
▶ It shows blockage – site,extent, severity
▶ Corkscrew appearance of vessels – dilation of vasa vasorum
▶ Inverted tree/spider legs pattern of collaterals
▶ Severe vasospasm – corragated /rippled artery appearance
Distal run off – amount of dye filling in the main vessel distal to the
obstruction through collaterals
▶ Distal run off
▶ Good – then ischemia is compensated
▶ Poor – then it is decompensated
▶ PLETHYSMOGRAPHY:
▶ Segmental plethysmography is introduced by placing venous
occlusion cuffs around thigh, calf, ankle
▶ Cuffs inflated to 65mmhg and pulsation is quantitative
measure of arterial diseases.
▶ Digital subtraction angiography:(DSA)
▶ Only vascular system seen
TREATMENT
• MICROCIRCULATION IN A BETTER WAY SO AS TO INCREASE THE OXYGENATION
• ▶ LOW DOSE ASPIRINE 75MG OD- ANTI THROMBOTIC
• ▶ PROSTACYCLINS, TICLOPIDINE, PRAXYLENE, CARNITINE- ANTI THROMBOTIC
EFFECT
• ▶ CLOPIDOGREL 75MG, ATORVOSTATIN 10MG
▶ Quit smoking
▶ Pentoxiphylline increases flexibility of rbc’ss and hep them reach the
▶ Cilostazole 100mg BD is a phosphodiasterase inhibitor which improves
circulation
▶ All the drugs act on collateral level than at the diseased vessel
CARE OF LIMBS
▶ Buergers position and exercise
•▶ Regular graded exercises upto the point of claudication
improves collateral circulation
•▶ In buerger’s position head end of bed is raised, foot end of bed
is lowered to improve circulation
•▶ In buerger’s exercise leg is elevated and lowered alternatively
each for 2 mins for several times at a time to improve collateral
circulation
CARE OF FEET
▶ Exposure of
feet cold and warm
temperature should be
avoided
▶ Trauma and
pressure in the feet
should be avoided
▶ Dryness of feet
and leg should be
avoided by applying oil
▶ Footwear
should be worn with
socks
▶ Heel raise of
2cm should be used
▶ reduces the calf
muscle work which
leads to improved
claudication time
CHEMICAL SYMPATHECTOMY
▶ Symathetic chain is blocked to achieve vaso dilation by injecting local anaesthesic
paravertebrally besides bodies of L2 L3 L4 vertebrae infront of lumbar fascia
▶ 5ml phenol in water can be used for long term efficiency, it is done under C- arm
guidance
▶ Feet will become warm immediately after injection Complications
1) Spinal cord ischemia, risk of injecting phenol into IVC or aorta
SURGICAL MANAGEMENT
▶ Omentoplasty - to revascularise the affected
limb
•▶ Profundoplasty – is done for blockage in the profunda femoris artery
so as to open more collaterals across the knee joint
•▶ lumbar sympathetectomy- to increase cutaneous perfusion as to
promote ulcer healing, but it may divert blood from muscle towards skin
causing more ischemia
•▶ Amputations are done at different levels depending upon the
severity usually below knee or above knee amputations are done
OMENTOPLASTY
ABOVE KNEE
AMPUTATION
▶ Ilzarov’s method- bone lengthening helps in
improving the rest pain and claudication by
creating neo-osteogenesis and improving
overall blood supply

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Care of the Patient with Beugers Disease

  • 2. THROMBOANGITIS OBLITRANS (TAO) Buerger’s disease is a segmental ,progressive ,occlusive ,inflammatory disease of small and medium sized vessels with superficial thrombophlebitis often may present as Raynaud’s phenomenon with micro abscesses, along with neutrophil and gaint cell infiltration , with skip lesions. More common in lower limbs than upper limbs
  • 3. INCIDENCE ▶ Very commonly seen in young and middle aged males (20 – 40 yrs) ▶ Seen only in smokers and tobacco users ▶ Rarely can occur in females smokers ▶ Common in jewish people
  • 4. RISK FACTORS ▶ Smoking is prime risk factor >40 pack years ▶ hormonal influence ,familial factors ▶ Hypersensitivity to cigarette , ▶ Altered autonomic functions ▶ Lower socioeconomic group , ▶ Recurrent minor feet injuries ▶ Poor hygiene
  • 5. SHIANOYA’S CRITERIA OF BUERGER’S DISEASE ▶ Male Tobacco user ▶ Disease onset before 45 yrs ▶ Distal extremity involved first with out embolic or atherosclerotic features ▶ Absence of diabetes mellitus or hyperlipidemia ▶ With or without thrombophlebitis
  • 6. CLASSIFICATION OF BUERGER’S DISEASE ▶ Type 1 : upper limb TAO ▶ Type 2 : involving legs & feet – crural/infrapopliteal ▶ Type 3 : femoropopliteal ▶ Type 4 : aortoiliofemoral ▶ Type 5 : generalised
  • 7. CLINICAL FEATURES ▶ Common in male smokers between 20-40 yrs of age group – smoker’s disease ▶ Intermittent claudication pain in foot and calf ▶ Recurrent migratory superficial thrombophlebitis Claudication pain Rest pain Ulceration and gangrene
  • 8. CLINICAL FEATURES ▶ Absence / feeble pulsations distal to proximal ,dorsalis pedis ,posterior tibial , popliteal ,femoral arteries in lower limbs ▶ It may also present as Raynaud’s phenomenon
  • 9. INVESTIGATIONS ▶ Blood sugar levels – DIABETES MELLITUS ▶ Lipid profile- any dyslipidemia ▶ Decreasesd Hb levels – delayed healing ▶ WBC count - infection
  • 10. • CORKSCREW APPEARANCE OF • COLLATERALS DUE TO DILATION OF VASA VASORUM Arterial flow , flow rate, velocity, stenosis, block.
  • 11. TRANSFEMORAL RETROGRADE ANGIOGRAM ▶ It shows blockage – site,extent, severity ▶ Corkscrew appearance of vessels – dilation of vasa vasorum ▶ Inverted tree/spider legs pattern of collaterals ▶ Severe vasospasm – corragated /rippled artery appearance Distal run off – amount of dye filling in the main vessel distal to the obstruction through collaterals ▶ Distal run off ▶ Good – then ischemia is compensated ▶ Poor – then it is decompensated
  • 12.
  • 13.
  • 14. ▶ PLETHYSMOGRAPHY: ▶ Segmental plethysmography is introduced by placing venous occlusion cuffs around thigh, calf, ankle ▶ Cuffs inflated to 65mmhg and pulsation is quantitative measure of arterial diseases.
  • 15.
  • 16. ▶ Digital subtraction angiography:(DSA) ▶ Only vascular system seen
  • 17. TREATMENT • MICROCIRCULATION IN A BETTER WAY SO AS TO INCREASE THE OXYGENATION • ▶ LOW DOSE ASPIRINE 75MG OD- ANTI THROMBOTIC • ▶ PROSTACYCLINS, TICLOPIDINE, PRAXYLENE, CARNITINE- ANTI THROMBOTIC EFFECT • ▶ CLOPIDOGREL 75MG, ATORVOSTATIN 10MG ▶ Quit smoking ▶ Pentoxiphylline increases flexibility of rbc’ss and hep them reach the ▶ Cilostazole 100mg BD is a phosphodiasterase inhibitor which improves circulation ▶ All the drugs act on collateral level than at the diseased vessel
  • 18. CARE OF LIMBS ▶ Buergers position and exercise •▶ Regular graded exercises upto the point of claudication improves collateral circulation •▶ In buerger’s position head end of bed is raised, foot end of bed is lowered to improve circulation •▶ In buerger’s exercise leg is elevated and lowered alternatively each for 2 mins for several times at a time to improve collateral circulation
  • 19.
  • 20. CARE OF FEET ▶ Exposure of feet cold and warm temperature should be avoided ▶ Trauma and pressure in the feet should be avoided ▶ Dryness of feet and leg should be avoided by applying oil ▶ Footwear should be worn with socks ▶ Heel raise of 2cm should be used ▶ reduces the calf muscle work which leads to improved claudication time
  • 21. CHEMICAL SYMPATHECTOMY ▶ Symathetic chain is blocked to achieve vaso dilation by injecting local anaesthesic paravertebrally besides bodies of L2 L3 L4 vertebrae infront of lumbar fascia ▶ 5ml phenol in water can be used for long term efficiency, it is done under C- arm guidance ▶ Feet will become warm immediately after injection Complications 1) Spinal cord ischemia, risk of injecting phenol into IVC or aorta
  • 22.
  • 23. SURGICAL MANAGEMENT ▶ Omentoplasty - to revascularise the affected limb •▶ Profundoplasty – is done for blockage in the profunda femoris artery so as to open more collaterals across the knee joint •▶ lumbar sympathetectomy- to increase cutaneous perfusion as to promote ulcer healing, but it may divert blood from muscle towards skin causing more ischemia •▶ Amputations are done at different levels depending upon the severity usually below knee or above knee amputations are done
  • 26.
  • 27. ▶ Ilzarov’s method- bone lengthening helps in improving the rest pain and claudication by creating neo-osteogenesis and improving overall blood supply