Cardiovascular prevention. com is a website for prevention of cardiovascular disease. In this slide presentation you can find the burden of cardiovascular disease in same Countries
UCSI University Pharmacy students executed their 9th Public Health Campaign in Mambau, Negeri Sembilan. Here are just some of the materials that was part of their exhibition.
UCSI University Pharmacy students executed their 9th Public Health Campaign in Mambau, Negeri Sembilan. Here are just some of the materials that was part of their exhibition.
The DARK Side of Sugar Teaching Project Lauren Collie
Teaching project created for Community Health Nursing Practicum. This project was presented at various health clinics whose targeted population was to serve the homeless, underinsured, or those going through rehab.
includes several diseases process including various diseases of the heart, stroke and high blood pressure, congestive heart failure and atherosclerosis
The DARK Side of Sugar Teaching Project Lauren Collie
Teaching project created for Community Health Nursing Practicum. This project was presented at various health clinics whose targeted population was to serve the homeless, underinsured, or those going through rehab.
includes several diseases process including various diseases of the heart, stroke and high blood pressure, congestive heart failure and atherosclerosis
Find In-depth Review And Infographic About Cancer Prevention. Learn about global statistics, cancer risk factors, cancer screening, case of angelina jolie, prevention tips and treatment options.
Columbia University Medical Center Social Media for Health Care Professionals...Doug Levy
Slides used during presentations at the first CUMC/ColumbiaDoctors Social Media Conference, held on Aug. 8, 2013. Speakers included Sree Sreenivasan, Ivan Oransky, Doug Levy, Gina Czark, Azra Raza, Skeptical Scalpel, Tamar Schiller, Michele Hoos.
Recent Epidemic Outbreaks - Around the WorldMaps of World
Find out here what is Epidemic Outbreaks? This is an interesting infographic page provides information on selected public health emergency and other outbreaks of infectious disease topics of recent public interest.These include Ebola, MERS, SARS and others.
Long-lasting alterations to DNA methylation and ncRNAs could underlie the eff...Ben Laufer
Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene expression, neurodevelopment and behavior. What mechanisms initiate and maintain these changes are not known, but current research suggests a role for alcohol-induced epigenetic changes. We assessed alterations to adult mouse brain tissue by assaying DNA cytosine methylation and small noncoding RNA (ncRNA) expression, specifically the microRNA (miRNA) and small nucleolar RNA (snoRNA) subtypes. We found long-lasting alterations in DNA methylation as a result of fetal alcohol exposure, specifically in the imprinted regions of the genome harboring ncRNAs and sequences interacting with regulatory proteins. The findings of this study help to expand on the mechanisms behind the long-lasting changes in the brain transcriptome of FASD individuals.
Webinar Link: http://www.youtube.com/watch?v=fzdc0GIdCnA
http://www.thinkred.co.za/get-involved/events | Thousands of people around the globe are affected by at least one type of Cardiovascular Disease (CVD) every day. This only emphasises the importance of heart health in this day and age. Learn what CVD is about the impact that it has had on people over the years. With simple diet and lifestyle changes many diagnosed individuals can overcome this threat.
Global Medical Cures™ | NEW YORK STATE- Cardiovascular Disease MortalityGlobal Medical Cures™
Global Medical Cures™ | NEW YORK STATE- Cardiovascular Disease Mortality
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
This was a lecture in the course "Significant Medical Conditions in Seniors" presented at Peer Learning in Chapel Hill, NC, USA in 2016 by Michael C. Joseph, MD, MPH.
An Overview on Sudden Cardiac Death by Bibin Rijo W | Aswin A V | Divika S | ...ijtsrd
As the most prevalent cause of death in developing nations is heart disease, over 7 lakh people in India and over 4 5 million worldwide pass away from sudden cardiac death SCD each year. It is the most prevailing kind of unexpected mortality brought on by cardiac anomalies like congenital heart disorders, hereditary channelopathies, heart failure and ischemic heart diseases. Nevertheless, non cardiac causes such aortic syndromes, stroke and pulmonary embolism can also result in sudden cardiac death and must to be taken into account as alternative diseases. Additionally, younger individuals experience sudden cardiac death, which is pertaining to obesity, stress, lifestyle changes, alcoholism and fibrosis non ischemic causes of sudden cardiac death . This study exemplifies the causes of sudden cardiac death SCD , most notably for those with cardiovascular diseases. Bibin Rijo W | Aswin A V | Divika S | Dr. K C Arul Prakasam | Dr. N Senthil Kumar "An Overview on Sudden Cardiac Death" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63453.pdf Paper Url: https://www.ijtsrd.com/pharmacy/other/63453/an-overview-on-sudden-cardiac-death/bibin-rijo-w
Similar to Cardiovascular Disease prevention - Epidemiology, cardio,healt (20)
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
1. CardioVascularDisease
1
C di
Cardiovascular di
l diseases (CVD) are th main cause
the i
of death in the industrialized countries. But they
are d
dangerously increasing in th emerging
l i i i the i
Countries.
The main forms of CVD are coronary heart disease
(CHD):
Acute myocardial infarction (AMI), Angina pectoris,
sudden cardiac death (SD)
Stroke: Ischemic and Haemorrhagic;
Peripheral artery disease, aortic aneurysm
www.cardiovascularprevention.com
2. Age-standardised death rates, per 100.000, from CHD,
1968 2002,
1968-2002, selected countries, the world (1)
2
From: Steven Allender, Viv Peto,
Peter Scarborough, Asha
Kaur and Mike Rayner (2008)
Coronary heart disease
statistics. British Heart
Foundation: London.
www.cardiovascularprevention.com
3. Age-standardised death rates, per 100.000, from CHD,
1968 2002,
1968-2002, selected countries, the world (2)
3
From: Steven Allender, Viv Peto,
Peter Scarborough, Asha
Kaur and Mike Rayner (2008)
Coronary heart disease
statistics. British Heart
Foundation: London.
www.cardiovascularprevention.com
4. Cardiovascular Disease in Europe
p
4
Fi t cause of d th counting 41% of all d th
First f death ti % f ll deaths
(Eurostat 2003)
1.2 milioni d
ili i deaths i Europe / year
h in
1/3 of year of life expectancy lost by CVD’s
premature death
www.cardiovascularprevention.com
7. CVD in ITALY(year 2003)
(y 3)
7
A t Coronary S d
Acute C Syndrome
280.000 Male
78.000 Female
50.000 Sudden Cardiac Death
AMI or SD as first onset of CHD
Only 30% of persons having traditional risk factors show
signs and symptoms of CHD
In 68% of younger patients, without traditional risk
factors there are subcritical coronary artery stenoses( <
f h b ii l (
50%).
www.cardiovascularprevention.com
8. Mortality Year - ISTAT (Ital )
(Italy)
8
Cardiovascular
Disease 237.198
Cancer 163.070
Sudden Death 54.000
54 000
www.cardiovascularprevention.com
9. 9
DISEASES ASSOCIATED WITH
HIGHT Cardiovascular mortality
Diabetes m.
Heart Failure
Ictus (ischemic /haemorrhagic)
( / g )
www.cardiovascularprevention.com
10. Cardiovascular Disease in United Kingdom
-2006-
2006
10
Diseases of the heart and circulatory system (
y y (cardiovascular disease or CVD) are the main cause of
)
death in the UK and account for almost 198,000 deaths each year. More than one in three deaths
(35%) are from CVD each year. The main forms of CVD are coronary heart disease (CHD: Acute
myocardial infarction, Angina pectoris, sudden cardiac death) and stroke. About half (48%) of all
deaths from CVD are from CHD and more than a quarter (28%) are from stroke.
CHD by itself is the most common cause of death in the UK. Around one in five men and one in seven
UK
women die from the disease. CHD causes around 94,000 deaths in the UK each year.
Other forms of heart disease cause over 31,000 deaths in the UK each year so in total there were just
under 126,000 deaths from heart disease in the UK in 2006.
Premature mortality(death before the age of 75).
CVD is one of the main causes of premature death in the UK 30% of premature deaths in men and
22% of premature deaths in women were from CVD in 2006. CVD caused just over 53,000
premature deaths in the UK in 2006.
CHD, by itself, is the most common cause of premature death in the UK About one fifth (19%) of
premature deaths in men and one in ten (10%) premature deaths in women were from CHD.
CHD caused almost 31,000 premature deaths in the UK in 2006.
Other forms of heart disease cause more than 7,500 premature deaths in the UK each year. In total
there were over 38,000 premature deaths from heart disease in the UK in 2006 - around one fifth
of all premature deaths.
From: Steven Allender, Viv Peto, Peter Scarborough, Asha Kaur and Mike Rayner (2008) Coronary
heart disease statistics. British Heart Foundation: London.
www.cardiovascularprevention.com
11. DEATHS BY SEX, AGE, UNITED KINGDOM
- 2006
2006-
11
From: Steven Allender, Viv Peto,
Peter Scarborough, Asha
Kaur and Mike Rayner (2008)
Coronary heart disease
statistics. British Heart
Foundation: London.
www.cardiovascularprevention.com
12. USA Death rate in 2003
• Th 2003 preliminary CVD d th rates were 364 2 f males
The li i death t 364.2 for l
and 262.5 for females.
• Cancer death rates were 232.3 for males and 160.2 for
females.
f l
• Breast cancer claimed the lives of 41 566 females in 2003.
• Lung cancer claimed 67 894.
g
• Death rates for females were 25.2 for breast cancer and 41.1
for lung cancer.
• One in 30 female deaths are from breast cancer, while 1 in
cancer
2.6 are from CVD.
• Based on preliminary 2003 mortality, CVD caused about a
death a minute among females over
• 480 000 female lives every year.
www.cardiovascularprevention.com
12
13. Other causes of death in 2003 in
USA (preliminary data)
• Cancer 554 643
• Accidents 105 695
• Alzheimer’s disease 63 343
• HIV (AIDS) 13 544
544.
www.cardiovascularprevention.com
13
14. U.S.A. Data 1999-2002
999
14
Of the 71 300 000 American adults with 1 or more types of
cardiovascular disease (CVD), 27 400 000
are estimated to be age 65 or older
g 5
High blood pressure 65 000 000.
Coronary heart disease
y 13 200 000.
– Myocardial infarction (MI, or heart attack)
7 200 000.
– Angina pectoris (AP, or chest pain) 6 500 000.
• Heart failure 5 000 000.
Stroke 5 500 000.
Congenital cardiovascular defects 1 000 000.
www.cardiovascularprevention.com
15. U.S.A. Data 2003 & cost 2006
www.cardiovascularprevention.com
15
16. CARDIOVASCULAR DISEASE IN CANADA (1)
These statistics are based on 2004 d t (f
Th t ti ti b d data (from St ti ti C
Statistics Canada)
d )
Cardiovascular disease (heart disease, diseases of the blood vessels
and stroke) acco nts for the death of more Canadians than an other
accounts any
disease.
Every 7 minutes in Canada, someone dies from heart disease or
stroke.
stroke
Cardiovascular disease accounted for 72,338 deaths:
32% of all deaths in Canada
31% of all male deaths
33% of all female deaths
In 2004, of all cardiovascular deaths:
54% were due to ischemic heart disease
20% to stroke
25% to heart attack
Cost of cardiovascular diseases
Heart disease and stroke costs the Canadian economy more than $18
billion every year in physician services, hospital costs, lost wages and
decreased productivity.
www.cardiovascularprevention.com
16
17. CARDIOVASCULAR DISEASE IN CANADA (2)
These statistics are based on 2004 data (from Statistics Canada)
Cardiac arrest
About 40,000 Canadians experience cardiac arrest every year.
Ab t 40 000 C di i di t
Less than 5% of those who have a cardiac arrest outside of a hospital
survive.
Congestive heart failure
It is estimated that there are 400 000 Canadians living with congestive
400,000
heart failure (CHF).
Stroke
More than 50,000 strokes occur in Canada each year. That’s one stroke
every 10 minutes.
y
Stroke is the third leading cause of death in Canada.
Each year, more than 14,000 Canadians die from stroke.
Each year, more women than men die from stroke.
y
www.cardiovascularprevention.com
17
18. ACUTE CORONARY SINDROME IN INDIA
18
India has the largest percentage of heart disease in the world
X i et al's, examined th i id
Xavier t l' i d the incidence of STEMI and non-STEMI among
f d STEMI
almost 21 000 patients from 89 centers in 50 Indian cities. They found that
more than 60% of these patients were diagnosed with STEMI, mean age was
57.5 years (although STEMI patients tended to be even younger), and the
vast majority were f
j i from l
lower-middle-income or poor f ili
iddl i families.
The Indians were, on average, 57,5 years of age compared with 70.7 years for
the European whites
whites.
Reinfarction, and stroke rates and 30-day death, were higher for STEMI
patients than non-STEMI, and mortality, notably, was significantly higher in
poor patients than in rich patients.
They also had significantly increased prevalence of diabetes, hypertension,
history of CAD compared with European whites.
And triple-vessel disease was more common in the Indian Asians than in the
whites.
whites
Almost all STEMI and non-STEMI patients were treated with antiplatelet
drugs (primarily aspirin), but use of thrombolytics, ACE inhibitors or
Angiotensin-Receptor Blockers, beta blockers, statins, omega 3 fatty-acids
and PCI/CABG were all far lower than rates seen in the West.
d ll f l th t i th W t
www.cardiovascularprevention.com
19. India: Mortality rates and
socioeconomic status
i 19
i t t
Mortality
M t lit Rich
Ri h Lower P
L Poor (%) p
(%) middle
class
(%)
Unadjusted mortality 5.5 6.5 8.2 <0.0001
Mortality adjusted for 7.2 6.4 6.6 0.97
risk f t
i k factors, location
l ti
of infarct, and
treatments
From: Xavier D. et al. Lancet 2008; 371:1435-1442.
www.cardiovascularprevention.com
20. Ten-year risk of CHD event (%) in 60-year-
y ( ) y
olds British minority Ethnic groups
20
Ethnic
Eth i group Male
M l Male
M l Female
F l Female
F l
nonsmoker smoker nonsmoker smoker
Indian 18.5 27.9 6.4 10.0
Pakistani 21.3 31.8 9.8 15.3
Bangladeshi 21.2 31.7 5.3 8.3
All South 19.5 29.3 7.1 11.1
Asians
Chinese 6.1
61 9.6
96 1.1
11 1.8
18
Caribbean 5.4 8.5 8.6 13.4
Black African 8.9 13.9 3.6 5.7
Irish 13.7 20.9 6.8 10.6
Framingham 11.8 18.2 7.1 11.7
score
From: P Brindle, M May, et Al: Heart 2006;92:1595–1602. www.cardiovascularprevention.com
doi: 10.1136/hrt.2006.092346
21. Ten-year risk of CVD event (%) in 60-year-
y ( ) y
olds British minority Ethnic groups
21
Ethnic group Male Male Female Female
nonsmoker smoker nonsmoker smoker
Indian 22.4 36.7 8.7 15.1
Pakistani 24.7 40.0 13.4 22.8
Bangladeshi 24.9 40.4 7.4 13.0
All South 23.6 38.5 9.7 16.9
Asians
Chinese 11.1
11 1 19.1
19 1 2.5
25 4.4
44
Caribbean 13.3 22.7 9.7 16.9
Black African 20.1
20 1 33.3
33 3 10.8
10 8 18.7
18 7
Irish 16.0 27.0 9.1 15.8
g
Framingham 14.1 22.3 8.7 14.7
score
From: P Brindle, M May, et Al: Heart 2006;92:1595–1602. doi: 10.1136/hrt.2006.092346
www.cardiovascularprevention.com
22. Health care costs of CVD, CHD and stroke
f ,
by EU country, 2006, Europe
CVD CHD Stroke
Cost per % of total Cost per % of total Cost per % of total
capita health capita health capita health
Country (€) expenditure (€) expenditure (€) expenditure
Austria 198 6 43 1 35 1
From: Steven Allender, Viv Peto,
Belgium 193 6 46 1 27 1 Peter Scarborough, Asha
Bulgaria Ì5 14 6 2 7 3
Cyprus 59 5 18 2 7 l Kaur and Mike Rayner (2008)
Czech Republic 107 13 25 3 16 2
Coronary heart disease
Denmark
Estonia
182
77
5
15
44
22
1
4
37
14
l
3
statistics. British Heart
Finland 237 10 52 2 65 3 Foundation: London.
France 207 7 32 ! 2; 1
Germany 413 14 96 3 58 1
Greece 173 10 46 3 44 2
Hungary 75 111 15 2 10 1
Ireland 183 6 46 1 26 1
Italy 235 in 45 2 45 2
Latvia
L t i 47 9 13 3 8 2
Lithuania 59 13 14 3 14 3
Luxembourg 252 5 60 1 24 0
Malta 72 6 IS 1 5 0
Netherlands 271 9 73 2 78 3
Poland 74 17 18 4 10 2
Portugal 151 LO 33 2 27 2
Romania 14 15 6 3 6 2
Slovakia 74 13 21 4 11 2
Slovenia 91 7 19 1 12 1
Spain 130 7 31 2 17 1
Sweden 308 10 62 2 52 2
UK 313 12 71 3 69 3
Total EU 223 10 49 2 38 2
22 www.cardiovascularprevention.com
23. Alter et al The Proliferation of Cardiac Technology Circulation January 24, 2006
In Canada 23 www.cardiovascularprevention.com
24. Lucas et al Temporal Trends in Cardiac Testing and Treatment- USA- Circulation January 24, 2006
24 www.cardiovascularprevention.com