Brain-based learning is an approach that considers how the human brain learns best. It focuses on addressing student learning outcomes based on cognitive development and how the brain learns differently as people age. Some key principles are that each brain is unique, stress can impair learning, emotions are critical, and learning involves both the mind and body. Strategies for brain-based learning include chunking information, respecting individual differences, using moderate stress, improving metacognition, allowing non-learning time, and trial and error learning. The goal is to positively influence education by understanding how the brain works.