This document provides an introduction and overview of the British Pharmacopoeia (BP), British Pharmaceutical Codex, United States Pharmacopoeia-National Formulary (USP-NF), Extra Pharmacopoeia (Martindale), and The Merck Index. It describes the origins, contents, and purpose of each compendium for establishing drug standards. The BP, USP-NF, and Martindale set mandatory standards for active substances and formulated preparations. The British Pharmaceutical Codex provides additional information on drugs and preparations not included in the BP. The Merck Index is a reference work for information on chemicals, drugs, and biologicals.

1. INTRODUCTION OF BP & USP
Mr. Ajay Kumar Dubey, Assistant Professor, Institute of Pharmacy
Subject- Inorganic Pharmaceutical Chemistry (BP104T)
Email- a84dubey@gmail.com
Dr. Manju Pandey, Director, Institute of Pharmacy
Email- director.pharma@srmu.ac.in
Shri Ramswaroop Memorial University, Barabanki-225003

2. The British Pharmacopoeia (BP)
• The British Pharmacopoeia (B.P.) It was first published in
1864.
• Since 1948, which is seventh edition of B.P. the new
edition of British Pharmacopoeia is published at intervals
of five years i.e. 1948, 1953, 1958, 1963, 1968, 1973.
• After 1973 the new edition was published in 1980 and
then in 1988, 1993, 1998, 2003, 2008.

3. After 2008 the new edition was published every year.
In addition to the publication of the pharmacopoeia, the
addendums are also published from time to time in
between two main editions.
 The BP contains monographs, which set out the
mandatory standards for active substances, excipients and
formulated preparations, together with General Notices,
Appendices (test methods, reagents, etc ) and Reference
Spectra.

4. • Volumes I and II Medicinal Substances
• Volume III Formulated Preparations Blood related
Preparations Immunological Products Radiopharmaceutical
Preparations Surgical Materials Homeopathic Preparations
• Volume IV Appendices Infrared Reference Spectra Index
• Volume V British Pharmacopoeia (Veterinary)
• Volume VI (CD-ROM version) British Pharmacopoeia
The British Pharmacopoeia

5. The British Pharmaceutical Codex
The British Pharmaceutical Codex differs from British
Pharmacopoeia in that :
• It contains many more drugs and preparation
• It provides standards for drugs surgical dressings and
pharmaceutical preparations not included in the
British Pharmacopoeia.

6. •It provides information on the actions and uses of drugs,
their undesirable effects, precaution and treatment of
poisoning.
•It contain formulae, method of preparation, dose,
container and storage conditions of most of the
preparations which are still extemporaneously prepared
in the pharmacy and dispensed by the pharmacists.
•These preparations include mixtures, powders, eye
drops, ear drops, liniments, lotions, ointments, creams,
pastes, suppositories etc.

7. United State Pharmacopoeia & National Formulary
• The United States Pharmacopoeia and National
Formulary (USP-NF) is an official public standards–
setting authority for all prescription and over–the–
counter medicines and other health care products
manufactured or sold in the United States.
• USP also sets recognized standards for food
ingredients and dietary supplements.

8. The United States Pharmacopoeia was originally published
in 1820 under the authority of the United States
Pharmacopoeial Convention and the National Formulary was
published in 1888 under the guidance of American
Pharmaceutical Association .
In 1974 the National Formulary was purchased by the
United States Pharmacopoeial Convention and from 1980
onwards only one official book of drug standards was
published under the heading, The United States
Pharmacopoeia and The National Formulary (USP-NF).

9. • The USP–NF is a three volume combination of
two official compendia, the United States
Pharmacopoeia (USP) and the National
Formulary (NF).
• Monographs for drug substances and
preparations are featured in the USP.
• Monographs for dietary supplements and
ingredients appear in a separate section of the
USP. Excipient monographs are in the NF.
United State Pharmacopoeia- National Formulary

10. EXTRA PHARMACOPOEIA
(MARTINDALE)
• The Extra Pharmacopoeia was first produced
in 1883 by William Martindale and is still
known as ‘Martindale ’ Published by The
Royal Pharmaceutical Society of Great Britain
• The term “Extra” means in this instance
“Outside”, because the book aimed to describe
drugs that were outside the British
Pharmacopoeia.

11. THE MERCK INDEX
• It is an encyclopedia of chemicals, drugs and
biologicals .
• The first edition was published in 1889 and the
eleventh edition was published in 1989 by
Merck & Co., Inc. Rahway, New Jersy , USA.
• The Merck Index is the definitive reference
work for scientists and professionals looking
for authoritative information on chemicals,
drugs and biologicals.

12. THANK YOU
REFERENCES-
https://en.wikipedia.org/wiki/Indian_Pharmacopoeia
https://www.slideshare.net/
 https://www.pharmtech.com/
Anand & Chatwal, Inorganic Pharmaceutical Chemistry