RARE and FAIR Science: Reproducibility and Research ObjectsCarole Goble
Keynote at JISC Digifest 2015 on Reproducibility and Research Objects in Scholarly Communication
Includes hidden slides
All material except maybe the IT Crowd screengrab reusable
Results Vary: The Pragmatics of Reproducibility and Research Object FrameworksCarole Goble
Keynote presentation at the iConference 2015, Newport Beach, Los Angeles, 26 March 2015.
Results Vary: The Pragmatics of Reproducibility and Research Object Frameworks
http://ischools.org/the-iconference/
BEWARE: presentation includes hidden slides AND in situ build animations - best viewed by downloading.
ISMB/ECCB 2013 Keynote Goble Results may vary: what is reproducible? why do o...Carole Goble
Keynote given by Carole Goble on 23rd July 2013 at ISMB/ECCB 2013
http://www.iscb.org/ismbeccb2013
How could we evaluate research and researchers? Reproducibility underpins the scientific method: at least in principle if not practice. The willing exchange of results and the transparent conduct of research can only be expected up to a point in a competitive environment. Contributions to science are acknowledged, but not if the credit is for data curation or software. From a bioinformatics view point, how far could our results be reproducible before the pain is just too high? Is open science a dangerous, utopian vision or a legitimate, feasible expectation? How do we move bioinformatics from one where results are post-hoc "made reproducible", to pre-hoc "born reproducible"? And why, in our computational information age, do we communicate results through fragmented, fixed documents rather than cohesive, versioned releases? I will explore these questions drawing on 20 years of experience in both the development of technical infrastructure for Life Science and the social infrastructure in which Life Science operates.
FAIRDOM - FAIR Asset management and sharing experiences in Systems and Synthe...Carole Goble
Over the past 5 years we have seen a change in expectations for the management of all the outcomes of research – that is the “assets” of data, models, codes, SOPs and so forth. Don’t stop reading. Data management isn’t likely to win anyone a Nobel prize. But publications should be supported and accompanied by data, methods, procedures, etc. to assure reproducibility of results. Funding agencies expect data (and increasingly software) management retention and access plans as part of the proposal process for projects to be funded. Journals are raising their expectations of the availability of data and codes for pre- and post- publication. The multi-component, multi-disciplinary nature of Systems Biology demands the interlinking and exchange of assets and the systematic recording
of metadata for their interpretation.
The FAIR Guiding Principles for scientific data management and stewardship (http://www.nature.com/articles/sdata201618) has been an effective rallying-cry for EU and USA Research Infrastructures. FAIRDOM (Findable, Accessible, Interoperable, Reusable Data, Operations and Models) Initiative has 8 years of experience of asset sharing and data infrastructure ranging across European programmes (SysMO and EraSysAPP ERANets), national initiatives (de.NBI, German Virtual Liver Network, UK SynBio centres) and PI's labs. It aims to support Systems and Synthetic Biology researchers with data and model management, with an emphasis on standards smuggled in by stealth and sensitivity to asset sharing and credit anxiety.
This talk will use the FAIRDOM Initiative to discuss the FAIR management of data, SOPs, and models for Sys Bio, highlighting the challenges of and approaches to sharing, credit, citation and asset infrastructures in practice. I'll also highlight recent experiments in affecting sharing using behavioural interventions.
http://www.fair-dom.org
http://www.fairdomhub.org
http://www.seek4science.org
Presented at COMBINE 2016, Newcastle, 19 September.
http://co.mbine.org/events/COMBINE_2016
Findable Accessable Interoperable Reusable < data |models | SOPs | samples | articles| * >. FAIR is a mantra; a meme; a myth; a mystery; a moan. For the past 15 years I have been working on FAIR in a bunch of projects and initiatives in Life Science projects. Some are top-down like Life Science European Research Infrastructures ELIXIR and ISBE, and some are bottom-up, supporting research projects in Systems and Synthetic Biology (FAIRDOM), Biodiversity (BioVel), and Pharmacology (open PHACTS), for example. Some have become movements, like Bioschemas, the Common Workflow Language and Research Objects. Others focus on cross-cutting approaches in reproducibility, computational workflows, metadata representation and scholarly sharing & publication. In this talk I will relate a series of FAIRy tales. Some of them are Grimm. Some have happy endings. Who are the villains and who are the heroes? What are the morals we can draw from these stories?
Research Objects: more than the sum of the partsCarole Goble
Workshop on Managing Digital Research Objects in an Expanding Science Ecosystem, 15 Nov 2017, Bethesda, USA
https://www.rd-alliance.org/managing-digital-research-objects-expanding-science-ecosystem
Research output is more than just the rhetorical narrative. The experimental methods, computational codes, data, algorithms, workflows, Standard Operating Procedures, samples and so on are the objects of research that enable reuse and reproduction of scientific experiments, and they too need to be examined and exchanged as research knowledge.
A first step is to think of Digital Research Objects as a broadening out to embrace these artefacts or assets of research. The next is to recognise that investigations use multiple, interlinked, evolving artefacts. Multiple datasets and multiple models support a study; each model is associated with datasets for construction, validation and prediction; an analytic pipeline has multiple codes and may be made up of nested sub-pipelines, and so on. Research Objects (http://researchobject.org/) is a framework by which the many, nested and contributed components of research can be packaged together in a systematic way, and their context, provenance and relationships richly described.
RARE and FAIR Science: Reproducibility and Research ObjectsCarole Goble
Keynote at JISC Digifest 2015 on Reproducibility and Research Objects in Scholarly Communication
Includes hidden slides
All material except maybe the IT Crowd screengrab reusable
Results Vary: The Pragmatics of Reproducibility and Research Object FrameworksCarole Goble
Keynote presentation at the iConference 2015, Newport Beach, Los Angeles, 26 March 2015.
Results Vary: The Pragmatics of Reproducibility and Research Object Frameworks
http://ischools.org/the-iconference/
BEWARE: presentation includes hidden slides AND in situ build animations - best viewed by downloading.
ISMB/ECCB 2013 Keynote Goble Results may vary: what is reproducible? why do o...Carole Goble
Keynote given by Carole Goble on 23rd July 2013 at ISMB/ECCB 2013
http://www.iscb.org/ismbeccb2013
How could we evaluate research and researchers? Reproducibility underpins the scientific method: at least in principle if not practice. The willing exchange of results and the transparent conduct of research can only be expected up to a point in a competitive environment. Contributions to science are acknowledged, but not if the credit is for data curation or software. From a bioinformatics view point, how far could our results be reproducible before the pain is just too high? Is open science a dangerous, utopian vision or a legitimate, feasible expectation? How do we move bioinformatics from one where results are post-hoc "made reproducible", to pre-hoc "born reproducible"? And why, in our computational information age, do we communicate results through fragmented, fixed documents rather than cohesive, versioned releases? I will explore these questions drawing on 20 years of experience in both the development of technical infrastructure for Life Science and the social infrastructure in which Life Science operates.
FAIRDOM - FAIR Asset management and sharing experiences in Systems and Synthe...Carole Goble
Over the past 5 years we have seen a change in expectations for the management of all the outcomes of research – that is the “assets” of data, models, codes, SOPs and so forth. Don’t stop reading. Data management isn’t likely to win anyone a Nobel prize. But publications should be supported and accompanied by data, methods, procedures, etc. to assure reproducibility of results. Funding agencies expect data (and increasingly software) management retention and access plans as part of the proposal process for projects to be funded. Journals are raising their expectations of the availability of data and codes for pre- and post- publication. The multi-component, multi-disciplinary nature of Systems Biology demands the interlinking and exchange of assets and the systematic recording
of metadata for their interpretation.
The FAIR Guiding Principles for scientific data management and stewardship (http://www.nature.com/articles/sdata201618) has been an effective rallying-cry for EU and USA Research Infrastructures. FAIRDOM (Findable, Accessible, Interoperable, Reusable Data, Operations and Models) Initiative has 8 years of experience of asset sharing and data infrastructure ranging across European programmes (SysMO and EraSysAPP ERANets), national initiatives (de.NBI, German Virtual Liver Network, UK SynBio centres) and PI's labs. It aims to support Systems and Synthetic Biology researchers with data and model management, with an emphasis on standards smuggled in by stealth and sensitivity to asset sharing and credit anxiety.
This talk will use the FAIRDOM Initiative to discuss the FAIR management of data, SOPs, and models for Sys Bio, highlighting the challenges of and approaches to sharing, credit, citation and asset infrastructures in practice. I'll also highlight recent experiments in affecting sharing using behavioural interventions.
http://www.fair-dom.org
http://www.fairdomhub.org
http://www.seek4science.org
Presented at COMBINE 2016, Newcastle, 19 September.
http://co.mbine.org/events/COMBINE_2016
Findable Accessable Interoperable Reusable < data |models | SOPs | samples | articles| * >. FAIR is a mantra; a meme; a myth; a mystery; a moan. For the past 15 years I have been working on FAIR in a bunch of projects and initiatives in Life Science projects. Some are top-down like Life Science European Research Infrastructures ELIXIR and ISBE, and some are bottom-up, supporting research projects in Systems and Synthetic Biology (FAIRDOM), Biodiversity (BioVel), and Pharmacology (open PHACTS), for example. Some have become movements, like Bioschemas, the Common Workflow Language and Research Objects. Others focus on cross-cutting approaches in reproducibility, computational workflows, metadata representation and scholarly sharing & publication. In this talk I will relate a series of FAIRy tales. Some of them are Grimm. Some have happy endings. Who are the villains and who are the heroes? What are the morals we can draw from these stories?
Research Objects: more than the sum of the partsCarole Goble
Workshop on Managing Digital Research Objects in an Expanding Science Ecosystem, 15 Nov 2017, Bethesda, USA
https://www.rd-alliance.org/managing-digital-research-objects-expanding-science-ecosystem
Research output is more than just the rhetorical narrative. The experimental methods, computational codes, data, algorithms, workflows, Standard Operating Procedures, samples and so on are the objects of research that enable reuse and reproduction of scientific experiments, and they too need to be examined and exchanged as research knowledge.
A first step is to think of Digital Research Objects as a broadening out to embrace these artefacts or assets of research. The next is to recognise that investigations use multiple, interlinked, evolving artefacts. Multiple datasets and multiple models support a study; each model is associated with datasets for construction, validation and prediction; an analytic pipeline has multiple codes and may be made up of nested sub-pipelines, and so on. Research Objects (http://researchobject.org/) is a framework by which the many, nested and contributed components of research can be packaged together in a systematic way, and their context, provenance and relationships richly described.
Being Reproducible: SSBSS Summer School 2017Carole Goble
Lecture 2:
Being Reproducible: Models, Research Objects and R* Brouhaha
Reproducibility is a R* minefield, depending on whether you are testing for robustness (rerun), defence (repeat), certification (replicate), comparison (reproduce) or transferring between researchers (reuse). Different forms of "R" make different demands on the completeness, depth and portability of research. Sharing is another minefield raising concerns of credit and protection from sharp practices.
In practice the exchange, reuse and reproduction of scientific experiments is dependent on bundling and exchanging the experimental methods, computational codes, data, algorithms, workflows and so on along with the narrative. These "Research Objects" are not fixed, just as research is not “finished”: the codes fork, data is updated, algorithms are revised, workflows break, service updates are released. ResearchObject.org is an effort to systematically support more portable and reproducible research exchange.
In this talk I will explore these issues in more depth using the FAIRDOM Platform and its support for reproducible modelling. The talk will cover initiatives and technical issues, and raise social and cultural challenges.
Being FAIR: FAIR data and model management SSBSS 2017 Summer SchoolCarole Goble
Lecture 1:
Being FAIR: FAIR data and model management
In recent years we have seen a change in expectations for the management of all the outcomes of research – that is the “assets” of data, models, codes, SOPs, workflows. The “FAIR” (Findable, Accessible, Interoperable, Reusable) Guiding Principles for scientific data management and stewardship [1] have proved to be an effective rallying-cry. Funding agencies expect data (and increasingly software) management retention and access plans. Journals are raising their expectations of the availability of data and codes for pre- and post- publication. The multi-component, multi-disciplinary nature of Systems and Synthetic Biology demands the interlinking and exchange of assets and the systematic recording of metadata for their interpretation.
Our FAIRDOM project (http://www.fair-dom.org) supports Systems Biology research projects with their research data, methods and model management, with an emphasis on standards smuggled in by stealth and sensitivity to asset sharing and credit anxiety. The FAIRDOM Platform has been installed by over 30 labs or projects. Our public, centrally hosted Asset Commons, the FAIRDOMHub.org, supports the outcomes of 50+ projects.
Now established as a grassroots association, FAIRDOM has over 8 years of experience of practical asset sharing and data infrastructure at the researcher coal-face ranging across European programmes (SysMO and ERASysAPP ERANets), national initiatives (Germany's de.NBI and Systems Medicine of the Liver; Norway's Digital Life) and European Research Infrastructures (ISBE) as well as in PI's labs and Centres such as the SynBioChem Centre at Manchester.
In this talk I will show explore how FAIRDOM has been designed to support Systems Biology projects and show examples of its configuration and use. I will also explore the technical and social challenges we face.
I will also refer to European efforts to support public archives for the life sciences. ELIXIR (http:// http://www.elixir-europe.org/) the European Research Infrastructure of 21 national nodes and a hub funded by national agreements to coordinate and sustain key data repositories and archives for the Life Science community, improve access to them and related tools, support training and create a platform for dataset interoperability. As the Head of the ELIXIR-UK Node and co-lead of the ELIXIR Interoperability Platform I will show how this work relates to your projects.
[1] Wilkinson et al, The FAIR Guiding Principles for scientific data management and stewardship Scientific Data 3, doi:10.1038/sdata.2016.18
Keynote: SemSci 2017: Enabling Open Semantic Science
1st International Workshop co-located with ISWC 2017, October 2017, Vienna, Austria,
https://semsci.github.io/semSci2017/
Abstract
We have all grown up with the research article and article collections (let’s call them libraries) as the prime means of scientific discourse. But research output is more than just the rhetorical narrative. The experimental methods, computational codes, data, algorithms, workflows, Standard Operating Procedures, samples and so on are the objects of research that enable reuse and reproduction of scientific experiments, and they too need to be examined and exchanged as research knowledge.
We can think of “Research Objects” as different types and as packages all the components of an investigation. If we stop thinking of publishing papers and start thinking of releasing Research Objects (software), then scholar exchange is a new game: ROs and their content evolve; they are multi-authored and their authorship evolves; they are a mix of virtual and embedded, and so on.
But first, some baby steps before we get carried away with a new vision of scholarly communication. Many journals (e.g. eLife, F1000, Elsevier) are just figuring out how to package together the supplementary materials of a paper. Data catalogues are figuring out how to virtually package multiple datasets scattered across many repositories to keep the integrated experimental context.
Research Objects [1] (http://researchobject.org/) is a framework by which the many, nested and contributed components of research can be packaged together in a systematic way, and their context, provenance and relationships richly described. The brave new world of containerisation provides the containers and Linked Data provides the metadata framework for the container manifest construction and profiles. It’s not just theory, but also in practice with examples in Systems Biology modelling, Bioinformatics computational workflows, and Health Informatics data exchange. I’ll talk about why and how we got here, the framework and examples, and what we need to do.
[1] Sean Bechhofer, Iain Buchan, David De Roure, Paolo Missier, John Ainsworth, Jiten Bhagat, Philip Couch, Don Cruickshank, Mark Delderfield, Ian Dunlop, Matthew Gamble, Danius Michaelides, Stuart Owen, David Newman, Shoaib Sufi, Carole Goble, Why linked data is not enough for scientists, In Future Generation Computer Systems, Volume 29, Issue 2, 2013, Pages 599-611, ISSN 0167-739X, https://doi.org/10.1016/j.future.2011.08.004
Scott Edmunds slides for class 8 from the HKU Data Curation (module MLIM7350 from the Faculty of Education) course covering science data, medical data and ethics, and the FAIR data principles.
What is Reproducibility? The R* brouhaha (and how Research Objects can help)Carole Goble
presented at 1st First International Workshop on Reproducible Open Science @ TPDL, 9 Sept 2016, Hannover, Germany
http://repscience2016.research-infrastructures.eu/
Being FAIR: Enabling Reproducible Data ScienceCarole Goble
Talk presented at Early Detection of Cancer Conference, OHSU, Portland, Oregon USA, 2-4 Oct 2018, http://earlydetectionresearch.com/ in the Data Science session
Capturing Context in Scientific Experiments: Towards Computer-Driven Sciencedgarijo
Scientists publish computational experiments in ways that do not facilitate reproducibility or reuse. Significant domain expertise, time and effort are required to understand scientific experiments and their research outputs. In order to improve this situation, mechanisms are needed to capture the exact details and the context of computational experiments. Only then, Intelligent Systems would be able help researchers understand, discover, link and reuse products of existing research.
In this presentation I will introduce my work and vision towards enabling scientists share, link, curate and reuse their computational experiments and results. In the first part of the talk, I will present my work for capturing and sharing the context of scientific experiments by using scientific workflows and machine readable representations. Thanks to this approach, experiment results are described in an unambiguous manner, have a clear trace of their creation process and include a pointer to the sources used for their generation. In the second part of the talk, I will describe examples on how the context of scientific experiments may be exploited to browse, explore and inspect research results. I will end the talk by presenting new ideas for improving and benefiting from the capture of context of scientific experiments and how to involve scientists in the process of curating and creating abstractions on available research metadata.
NSF Workshop Data and Software Citation, 6-7 June 2016, Boston USA, Software Panel
FIndable, Accessible, Interoperable, Reusable Software and Data Citation: Europe, Research Objects, and BioSchemas.org
Reproducibility Using Semantics: An Overviewdgarijo
Overview of the different approaches for addressing reproducibilities (using semantics) in laboratory protocols, workflow description and publication and workflow infrastructure. Furthermore, Research Objects are introduced as a means to capture the context and annotations of scientific experiments, together with the privacy and IPR concerns that may arise. This presentation was presented in Dagstuhl Seminar 16041: http://www.dagstuhl.de/16041
FAIR Data, Operations and Model management for Systems Biology and Systems Me...Carole Goble
FAIR Data, Operations and Model management for Systems Biology and Systems Medicine Projects given at 1st Conference of the European Association of Systems Medicine, 26-28 October 2016, Berlin. the FAIRDOM project is described.
Being Reproducible: SSBSS Summer School 2017Carole Goble
Lecture 2:
Being Reproducible: Models, Research Objects and R* Brouhaha
Reproducibility is a R* minefield, depending on whether you are testing for robustness (rerun), defence (repeat), certification (replicate), comparison (reproduce) or transferring between researchers (reuse). Different forms of "R" make different demands on the completeness, depth and portability of research. Sharing is another minefield raising concerns of credit and protection from sharp practices.
In practice the exchange, reuse and reproduction of scientific experiments is dependent on bundling and exchanging the experimental methods, computational codes, data, algorithms, workflows and so on along with the narrative. These "Research Objects" are not fixed, just as research is not “finished”: the codes fork, data is updated, algorithms are revised, workflows break, service updates are released. ResearchObject.org is an effort to systematically support more portable and reproducible research exchange.
In this talk I will explore these issues in more depth using the FAIRDOM Platform and its support for reproducible modelling. The talk will cover initiatives and technical issues, and raise social and cultural challenges.
Being FAIR: FAIR data and model management SSBSS 2017 Summer SchoolCarole Goble
Lecture 1:
Being FAIR: FAIR data and model management
In recent years we have seen a change in expectations for the management of all the outcomes of research – that is the “assets” of data, models, codes, SOPs, workflows. The “FAIR” (Findable, Accessible, Interoperable, Reusable) Guiding Principles for scientific data management and stewardship [1] have proved to be an effective rallying-cry. Funding agencies expect data (and increasingly software) management retention and access plans. Journals are raising their expectations of the availability of data and codes for pre- and post- publication. The multi-component, multi-disciplinary nature of Systems and Synthetic Biology demands the interlinking and exchange of assets and the systematic recording of metadata for their interpretation.
Our FAIRDOM project (http://www.fair-dom.org) supports Systems Biology research projects with their research data, methods and model management, with an emphasis on standards smuggled in by stealth and sensitivity to asset sharing and credit anxiety. The FAIRDOM Platform has been installed by over 30 labs or projects. Our public, centrally hosted Asset Commons, the FAIRDOMHub.org, supports the outcomes of 50+ projects.
Now established as a grassroots association, FAIRDOM has over 8 years of experience of practical asset sharing and data infrastructure at the researcher coal-face ranging across European programmes (SysMO and ERASysAPP ERANets), national initiatives (Germany's de.NBI and Systems Medicine of the Liver; Norway's Digital Life) and European Research Infrastructures (ISBE) as well as in PI's labs and Centres such as the SynBioChem Centre at Manchester.
In this talk I will show explore how FAIRDOM has been designed to support Systems Biology projects and show examples of its configuration and use. I will also explore the technical and social challenges we face.
I will also refer to European efforts to support public archives for the life sciences. ELIXIR (http:// http://www.elixir-europe.org/) the European Research Infrastructure of 21 national nodes and a hub funded by national agreements to coordinate and sustain key data repositories and archives for the Life Science community, improve access to them and related tools, support training and create a platform for dataset interoperability. As the Head of the ELIXIR-UK Node and co-lead of the ELIXIR Interoperability Platform I will show how this work relates to your projects.
[1] Wilkinson et al, The FAIR Guiding Principles for scientific data management and stewardship Scientific Data 3, doi:10.1038/sdata.2016.18
Keynote: SemSci 2017: Enabling Open Semantic Science
1st International Workshop co-located with ISWC 2017, October 2017, Vienna, Austria,
https://semsci.github.io/semSci2017/
Abstract
We have all grown up with the research article and article collections (let’s call them libraries) as the prime means of scientific discourse. But research output is more than just the rhetorical narrative. The experimental methods, computational codes, data, algorithms, workflows, Standard Operating Procedures, samples and so on are the objects of research that enable reuse and reproduction of scientific experiments, and they too need to be examined and exchanged as research knowledge.
We can think of “Research Objects” as different types and as packages all the components of an investigation. If we stop thinking of publishing papers and start thinking of releasing Research Objects (software), then scholar exchange is a new game: ROs and their content evolve; they are multi-authored and their authorship evolves; they are a mix of virtual and embedded, and so on.
But first, some baby steps before we get carried away with a new vision of scholarly communication. Many journals (e.g. eLife, F1000, Elsevier) are just figuring out how to package together the supplementary materials of a paper. Data catalogues are figuring out how to virtually package multiple datasets scattered across many repositories to keep the integrated experimental context.
Research Objects [1] (http://researchobject.org/) is a framework by which the many, nested and contributed components of research can be packaged together in a systematic way, and their context, provenance and relationships richly described. The brave new world of containerisation provides the containers and Linked Data provides the metadata framework for the container manifest construction and profiles. It’s not just theory, but also in practice with examples in Systems Biology modelling, Bioinformatics computational workflows, and Health Informatics data exchange. I’ll talk about why and how we got here, the framework and examples, and what we need to do.
[1] Sean Bechhofer, Iain Buchan, David De Roure, Paolo Missier, John Ainsworth, Jiten Bhagat, Philip Couch, Don Cruickshank, Mark Delderfield, Ian Dunlop, Matthew Gamble, Danius Michaelides, Stuart Owen, David Newman, Shoaib Sufi, Carole Goble, Why linked data is not enough for scientists, In Future Generation Computer Systems, Volume 29, Issue 2, 2013, Pages 599-611, ISSN 0167-739X, https://doi.org/10.1016/j.future.2011.08.004
Scott Edmunds slides for class 8 from the HKU Data Curation (module MLIM7350 from the Faculty of Education) course covering science data, medical data and ethics, and the FAIR data principles.
What is Reproducibility? The R* brouhaha (and how Research Objects can help)Carole Goble
presented at 1st First International Workshop on Reproducible Open Science @ TPDL, 9 Sept 2016, Hannover, Germany
http://repscience2016.research-infrastructures.eu/
Being FAIR: Enabling Reproducible Data ScienceCarole Goble
Talk presented at Early Detection of Cancer Conference, OHSU, Portland, Oregon USA, 2-4 Oct 2018, http://earlydetectionresearch.com/ in the Data Science session
Capturing Context in Scientific Experiments: Towards Computer-Driven Sciencedgarijo
Scientists publish computational experiments in ways that do not facilitate reproducibility or reuse. Significant domain expertise, time and effort are required to understand scientific experiments and their research outputs. In order to improve this situation, mechanisms are needed to capture the exact details and the context of computational experiments. Only then, Intelligent Systems would be able help researchers understand, discover, link and reuse products of existing research.
In this presentation I will introduce my work and vision towards enabling scientists share, link, curate and reuse their computational experiments and results. In the first part of the talk, I will present my work for capturing and sharing the context of scientific experiments by using scientific workflows and machine readable representations. Thanks to this approach, experiment results are described in an unambiguous manner, have a clear trace of their creation process and include a pointer to the sources used for their generation. In the second part of the talk, I will describe examples on how the context of scientific experiments may be exploited to browse, explore and inspect research results. I will end the talk by presenting new ideas for improving and benefiting from the capture of context of scientific experiments and how to involve scientists in the process of curating and creating abstractions on available research metadata.
NSF Workshop Data and Software Citation, 6-7 June 2016, Boston USA, Software Panel
FIndable, Accessible, Interoperable, Reusable Software and Data Citation: Europe, Research Objects, and BioSchemas.org
Reproducibility Using Semantics: An Overviewdgarijo
Overview of the different approaches for addressing reproducibilities (using semantics) in laboratory protocols, workflow description and publication and workflow infrastructure. Furthermore, Research Objects are introduced as a means to capture the context and annotations of scientific experiments, together with the privacy and IPR concerns that may arise. This presentation was presented in Dagstuhl Seminar 16041: http://www.dagstuhl.de/16041
FAIR Data, Operations and Model management for Systems Biology and Systems Me...Carole Goble
FAIR Data, Operations and Model management for Systems Biology and Systems Medicine Projects given at 1st Conference of the European Association of Systems Medicine, 26-28 October 2016, Berlin. the FAIRDOM project is described.
Keynote presentation delivered at ELAG 2013 in Gent, Belgium, on May 29 2013. Discusses Research Objects and the relationship to work my team has been involved in during the past couple of years: OAI-ORE, Open Annotation, Memento.
FAIR data and model management for systems biology.FAIRDOM
Written and presented by Carole Goble (University of Manchester) as part of Intelligent Systems for Molecular Biology (ISMB), Dublin. July 10th - 14th 2015.
PIDs, Data and Software: How Libraries Can Support Researchers in an Evolving...Sarah Anna Stewart
Presentation given at the M25 Consortium of Academic Libraries, CPD25 Event on 'The Role of the Library in Supporting Research'. Provides an introduction to data, software and PIDs and a brief look at how libraries can enable researchers to gain impact and credit for their research data and software.
Presentation slides on Open Science and research reproducibility. Presented by Gareth Knight (LSHTM Research Data Manager) on 18th September 2018, as part of an Open Science event for LSHTM Week 2018.
OSFair2017 Workshop | How FAIR friendly is the FAIRDOM Hub? Exposing metadata...Open Science Fair
Carole Goble presents the FAIRDOM | OSFair2017 Workshop
Workshop title: How FAIR friendly is your data catalogue?
Workshop overview:
This workshop will build upon the work planned by the EOSCpilot data interoperability task and the BlueBridge workshop held on April 3 at the RDA meeting. We will investigate common mechanisms for interoperation of data catalogues that preserve established community standards, norms and resources, while simplifying the process of being/becoming FAIR. Can we have a simple interoperability architecture based on a common set of metadata types? What are the minimum metadata requirements to expose FAIR data to EOSC services and EOSC users?
DAY 3 - PARALLEL SESSION 6 & 7
FAIR Data and Model Management for Systems Biology(and SOPs too!)Carole Goble
MultiScale Biology Network Springboard meeting, Nottingham, UK, 1 June 2015
FAIR Data and model management for Systems Biology
Over the past 5 years we have seen a change in expectations for the management of all the outcomes of research – that is the “assets” of data, models, codes, SOPs and so forth. Don’t stop reading. Yes, data management isn’t likely to win anyone a Nobel prize. But publications should be supported and accompanied by data, methods, procedures, etc. to assure reproducibility of results. Funding agencies expect data (and increasingly software) management retention and access plans as part of the proposal process for projects to be funded. Journals are raising their expectations of the availability of data and codes for pre- and post- publication. And the multi-component, multi-disciplinary nature of Systems Biology demands the interlinking and exchange of assets and the systematic recording of metadata for their interpretation.
Data and model management for the Systems Biology community is a multi-faceted one including: the development and adoption appropriate community standards (and the navigation of the standards maze); the sustaining of international public archives capable of servicing quantitative biology; and the development of the necessary tools and know-how for researchers within their own institutes so that they can steward their assets in a sustainable, coherent and credited manner while minimizing burden and maximising personal benefit.
The FAIRDOM (Findable, Accessible, Interoperable, Reusable Data, Operations and Models) Initiative has grown out of several efforts in European programmes (SysMO and EraSysAPP ERANets and the ISBE ESRFI) and national initiatives (de.NBI, German Virtual Liver Network, SystemsX, UK SynBio centres). It aims to support Systems Biology researchers with data and model management, with an emphasis on standards smuggled in by stealth.
This talk will use the FAIRDOM Initiative to discuss the FAIR management of data, SOPs, and models for Sys Bio, highlighting the challenges multi-scale biology presents.
http://www.fair-dom.org
http://www.fairdomhub.org
http://www.seek4science.org
Project Website: http://www.researchobject.org/
researchobjects.org is a community project that has developed an approach to describe and package up all resources used as part of an investigation as Research Objects (RO’s).
RO’s - provide two main features; a manifest - a consistent way to provide a well-typed, structured description of the resources used in an investigation; and a ‘bundle’ - a mechanism for packaging up manifests with resources as a single, publishable unit.
RO’s therefore carry the research context of an experiment - data, software, standard operating procedures (SOPs), models etc - and gather together the components of an experiment so that they are findable, accessible, interoperable and reproducible (FAIR). RO’s combine software and data into an aggregative data structure consisting of well described reconstructable parts.
RO’s have the potential to address a number of challenges pertinent to open research including: a) supporting interoperability between infrastructures by using ROs as a primary mechanism for exchange and publication b) supporting the evolution of research objects as a living collection, enabling provenance tracking c) providing the ability to pivot research object components (data, software, models) that are not restricted to the traditional publication.
Here we present work towards the development and adoption of ROs:
(i) A series of specifications and conventions, using community standards, for the RO manifest and RO bundles.
(ii) Implementations of Java, Python and Ruby APIs and tooling against those specifications;
(iii) Examples of representations of the RO models in various languages (e.g. JSON-LD, RDF, HTML).
The ELIXIR FAIR Knowledge Ecosystem for practical know-how: RDMkit and FAIRCo...Carole Goble
Presented at the FAIR Data in Practice Symposium, 16 may 2023 at BioITWorld Boston. https://www.bio-itworldexpo.com/fair-data. The ELIXIR European research Infrastructure for life science data is an inter-governmental organizations coordinating, integrating and sustaining FAIR data and software resources across its 23 nations. To help advise users, data stewards, project managers and service providers, ELIXIR has developed complementary community-driven, open knowledge resources for guiding FAIR Research Data Management (RDMkit) and providing FAIRification recipes (FAIRCookbook). 150+ people have contributed content so far, including representatives of the pharmaceutical industry.
Can’t Pay, Won’t Pay, Don’t Pay: Delivering open science, a Digital Research...Carole Goble
Invited talk, PHIL_OS, March 30-31 2023, Exeter
https://opensciencestudies.eu/whither-open-science. Includes hidden slides.
FAIR and Open Science needs Digital Research Infrastructure, which is a federated system of systems and needs funding models that are fit for purpose
Culture change needed for paying for Open Science’s infrastructure and funding support for data driven research needs more reality and less rhetoric
RO-Crate: packaging metadata love notes into FAIR Digital ObjectsCarole Goble
Abstract
slides available at: https://zenodo.org/record/7147703#.Y7agoxXP2F4
The Helmholtz Metadata Collaboration aims to make the research data [and software] produced by Helmholtz Centres FAIR for their own and the wider science community by means of metadata enrichment [1]. Why metadata enrichment and why FAIR? Because the whole scientific enterprise depends on a cycle of finding, exchanging, understanding, validating, reproducing), integrating and reusing research entities across a dispersed community of researchers.
Metadata is not just “a love note to the future” [2], it is a love note to today’s collaborators and peers. Moreover, a FAIR Commons must cater for the metadata of all the entities of research – data, software, workflows, protocols, instruments, geo-spatial locations, specimens, samples, people (well as traditional articles) – and their interconnectivity. That is a lot of metadata love notes to manage, bundle up and move around. Notes written in different languages at different times by different folks, produced and hosted by different platforms, yet referring to each other, and building an integrated picture of a multi-part and multi-party investigation. We need a crate!
RO-Crate [3] is an open, community-driven, and lightweight approach to packaging research entities along with their metadata in a machine-readable manner. Following key principles - “just enough” and “developer and legacy friendliness - RO-Crate simplifies the process of making research outputs FAIR while also enhancing research reproducibility and citability. As a self-describing and unbounded “metadata middleware” framework RO-Crate shows that a little bit of packaging goes a long way to realise the goals of FAIR Digital Objects (FDO)[4], and to not just overcome platform diversity but celebrate it while retaining investigation contextual integrity.
In this talk I will present the why, and how Research Object packaging eases Metadata Collaboration using examples in big data and mixed object exchange, mixed object archiving and publishing, mass citation, and reproducibility. Some examples come from the HMC, others from EOSC, USA and Australia, and from different disciplines.
Metadata is a love note to the future, RO-Crate is the delivery package.
[1] https://helmholtz-metadaten.de/en
[2] Scott, Jason The Metadata Mania, http://ascii.textfiles.com/archives/3181, June 2011
[3] Soiland-Reyes, Stian et al. “Packaging Research Artefacts with RO-Crate”. Data Science, 2022; 5(2):97-138, DOI: 10.3233/DS-210053
[4] De Smedt K, Koureas D, Wittenburg P. “FAIR Digital Objects for Science: From Data Pieces to Actionable Knowledge Units”. Publications. 2020; 8(2):21. https://doi.org/10.3390/publications8020021
Research Software Sustainability takes a VillageCarole Goble
The Research Software Alliance (ReSA) and the Netherlands eScience Center hosted a two-day international workshop to set the future agenda for national and international funders to support sustainable research software.
As the importance of software in research has become increasingly apparent, so has the urgent need to sustain it. Funders can play a crucial role in this respect by ensuring structural support. Over the past few years, a variety of methods for sustaining research software have been explored, including improving and extending funding policies and instruments. During the workshop, funding organizations joined forces to explore how they can effectively contribute to making research software sustainable.
This keynote helped frame the discussion from the perspective of community involvement in research software sustainability.
https://future-of-research-software.org/
this talk is available at Goble, Carole. (2022, November 8). Research Software Sustainability takes a Village. International funders workshop, The Future of Research Software, Amsterdam, The Netherlands. Zenodo. https://doi.org/10.5281/zenodo.7304596
“Bioscience has emerged as a data-rich discipline, in a transformation that is spreading as widely now as molecular biology in the twentieth century. We look forward to supporting new research careers, where data are valued and shared widely, where new software is a natural part of Biology, and where re-analysis and modelling are as creative as experimentation in understanding the rules of life and their applications.” Prof Andrew Millar FRS, chair Expert Group UKRI-BBSRC Review of data-intensive bioscience 2020.
Indeed - biomedical science is knowledge work and knowledge turning - the turning of observation and hypothesis through experimentation, comparison, and analysis into new, pooled knowledge. Turns depend on the FAIR and Open flow and availability of data and methods for automated processing and reproducible results, and on a society of scientists coordinating and collaborating.
For the past 25 years I have worked on the social and technical challenges in digital infrastructure to support scientific collaboration, data and method sharing, and automate scientific processing. Big ideas I have been instrumental in – sharing and publishing high quality computational workflows, semantic web technologies in bioscience, ecosystems of Research Objects as the currency of scholarly knowledge, FAIR data principles - preached revolution to inspire but need nudges* to get traction.
I’ll talk about making good on Andrew’s quote: what I’m doing to nudge and where we need to do more. I’ll also talk about my experiences as a woman in a digital infrastructure and computer science over the past 40 years – and some nudging is needed there too.
*Thaler RH, Sunstein CR (2008) Nudge: Improving Decisions about Health, Wealth, and Happiness. Yale University Press. ISBN 978-0-14-311526-7. OCLC 791403664.
https://www.bsc.es/research-and-development/research-seminars/hybrid-bsc-rslife-sessionbioinfo4women-seminar-love-money-fame-nudge-enabling-data-intensive
Open Research: Manchester leading and learningCarole Goble
Open and FAIR science has an international momentum. Large scale communities are striving to make and manage the digital infrastructure needed for scientists to be open as possible, closed as necessary, as expected by the NIH, OECD, UNESCO and the EC. ELIXIR is such a research infrastructure in Europe for Life Sciences. This talk will highlight two of ELIXIR's Open Science resources built by Open Science communities to enable life science researchers to be open, and led by Manchester. And how can we learn from these and bring these practices to Manchester?
Launch: Manchester Office for Open Research, 4th April 2022
https://www.openresearch.manchester.ac.uk/
RDMkit, a Research Data Management Toolkit. Built by the Community for the ...Carole Goble
https://datascience.nih.gov/news/march-data-sharing-and-reuse-seminar 11 March 2022
Starting in 2023, the US National Institutes of Health (NIH) will require institutes and researchers receiving funding to include a Data Management Plan (DMP) in their grant applications, including the making their data publicly available. Similar mandates are already in place in Europe, for example a DMP is mandatory in Horizon Europe projects involving data.
Policy is one thing - practice is quite another. How do we provide the necessary information, guidance and advice for our bioscientists, researchers, data stewards and project managers? There are numerous repositories and standards. Which is best? What are the challenges at each step of the data lifecycle? How should different types of data? What tools are available? Research Data Management advice is often too general to be useful and specific information is fragmented and hard to find.
ELIXIR, the pan-national European Research Infrastructure for Life Science data, aims to enable research projects to operate “FAIR data first”. ELIXIR supports researchers across their whole RDM lifecycle, navigating the complexity of a data ecosystem that bridges from local cyberinfrastructures to pan-national archives and across bio-domains.
The ELIXIR RDMkit (https://rdmkit.elixir-europe.org (link is external)) is a toolkit built by the biosciences community, for the biosciences community to provide the RDM information they need. It is a framework for advice and best practice for RDM and acts as a hub of RDM information, with links to tool registries, training materials, standards, and databases, and to services that offer deeper knowledge for DMP planning and FAIR-ification practices.
Launched in March 2021, over 120 contributors have provided nearly 100 pages of content and links to more than 300 tools. Content covers the data lifecycle and specialized domains in biology, national considerations and examples of “tool assemblies” developed to support RDM. It has been accessed by over 123 countries, and the top of the access list is … the United States.
The RDMkit is already a recommended resource of the European Commission. The platform, editorial, and contributor methods helped build a specialized sister toolkit for infectious diseases as part of the recently launched BY-COVID project. The toolkit’s platform is the simplest we could manage - built on plain GitHub - and the whole development and contribution approach tailored to be as lightweight and sustainable as possible.
In this talk, Carole and Frederik will present the RDMkit; aims and context, content, community management, how folks can contribute, and our future plans and potential prospects for trans-Atlantic cooperation.
Data policy must be partnered with data practice. Our researchers need to be the best informed in order to meet these new data management and data sharing mandates.
presented at WORKS 2021
https://works-workshop.org/
16th Workshop on Workflows in Support of Large-Scale Science
November 15, 2021
Held in conjunction with SC21: The International Conference for High Performance Computing, Networking, Storage and Analysis
presentation at https://researchsoft.github.io/FAIReScience/, FAIReScience 2021 online workshop
virtually co-located with the 17th IEEE International Conference on eScience (eScience 2021)
German Conference on Bioinformatics 2021
https://gcb2021.de/
FAIR Computational Workflows
Computational workflows capture precise descriptions of the steps and data dependencies needed to carry out computational data pipelines, analysis and simulations in many areas of Science, including the Life Sciences. The use of computational workflows to manage these multi-step computational processes has accelerated in the past few years driven by the need for scalable data processing, the exchange of processing know-how, and the desire for more reproducible (or at least transparent) and quality assured processing methods. The SARS-CoV-2 pandemic has significantly highlighted the value of workflows.
This increased interest in workflows has been matched by the number of workflow management systems available to scientists (Galaxy, Snakemake, Nextflow and 270+ more) and the number of workflow services like registries and monitors. There is also recognition that workflows are first class, publishable Research Objects just as data are. They deserve their own FAIR (Findable, Accessible, Interoperable, Reusable) principles and services that cater for their dual roles as explicit method description and software method execution [1]. To promote long-term usability and uptake by the scientific community, workflows (as well as the tools that integrate them) should become FAIR+R(eproducible), and citable so that author’s credit is attributed fairly and accurately.
The work on improving the FAIRness of workflows has already started and a whole ecosystem of tools, guidelines and best practices has been under development to reduce the time needed to adapt, reuse and extend existing scientific workflows. An example is the EOSC-Life Cluster of 13 European Biomedical Research Infrastructures which is developing a FAIR Workflow Collaboratory based on the ELIXIR Research Infrastructure for Life Science Data Tools ecosystem. While there are many tools for addressing different aspects of FAIR workflows, many challenges remain for describing, annotating, and exposing scientific workflows so that they can be found, understood and reused by other scientists.
This keynote will explore the FAIR principles for computational workflows in the Life Science using the EOSC-Life Workflow Collaboratory as an example.
[1] Carole Goble, Sarah Cohen-Boulakia, Stian Soiland-Reyes,Daniel Garijo, Yolanda Gil, Michael R. Crusoe, Kristian Peters, and Daniel Schober FAIR Computational Workflows Data Intelligence 2020 2:1-2, 108-121 https://doi.org/10.1162/dint_a_00033.
FAIR Data Bridging from researcher data management to ELIXIR archives in the...Carole Goble
ISMB-ECCB 2021, NIH/ODSS Session, 27 July 2021
ELIXIR is the pan-national European Research Infrastructure for Life Science data, whose 23 national nodes and the EBI coordinate the development and long-term sustainability of domain public databases. FAIR services, policies and curation approaches aim to build a FAIR connected data ecosystem of trusted domain repositories, from ENA, HPA and EGA to specialised resources like CorkOakDB and PIPPA for plant phenotypes. But this is only one part of the data landscape and often the end of data’s journey. The nodes support research projects to operate “FAIR data first”, working with institutional and national platforms that are often generic or designed for project-based data management. We need to bridge between project-based and community-based, and support researchers across their whole RDM lifecycle, navigating the complexity this ecosystem. The ELIXIR-CONVERGE project and its flagship RDMkit toolkit (https://rdmkit.elixir-europe.org) aims to do just that.
FAIR Computational Workflows
Computational workflows capture precise descriptions of the steps and data dependencies needed to carry out computational data pipelines, analysis and simulations in many areas of Science, including the Life Sciences. The use of computational workflows to manage these multi-step computational processes has accelerated in the past few years driven by the need for scalable data processing, the exchange of processing know-how, and the desire for more reproducible (or at least transparent) and quality assured processing methods. The SARS-CoV-2 pandemic has significantly highlighted the value of workflows.
This increased interest in workflows has been matched by the number of workflow management systems available to scientists (Galaxy, Snakemake, Nextflow and 270+ more) and the number of workflow services like registries and monitors. There is also recognition that workflows are first class, publishable Research Objects just as data are. They deserve their own FAIR (Findable, Accessible, Interoperable, Reusable) principles and services that cater for their dual roles as explicit method description and software method execution [1]. To promote long-term usability and uptake by the scientific community, workflows (as well as the tools that integrate them) should become FAIR+R(eproducible), and citable so that author’s credit is attributed fairly and accurately.
The work on improving the FAIRness of workflows has already started and a whole ecosystem of tools, guidelines and best practices has been under development to reduce the time needed to adapt, reuse and extend existing scientific workflows. An example is the EOSC-Life Cluster of 13 European Biomedical Research Infrastructures which is developing a FAIR Workflow Collaboratory based on the ELIXIR Research Infrastructure for Life Science Data Tools ecosystem. While there are many tools for addressing different aspects of FAIR workflows, many challenges remain for describing, annotating, and exposing scientific workflows so that they can be found, understood and reused by other scientists.
This keynote will explore the FAIR principles for computational workflows in the Life Science using the EOSC-Life Workflow Collaboratory as an example.
[1] Carole Goble, Sarah Cohen-Boulakia, Stian Soiland-Reyes,Daniel Garijo, Yolanda Gil, Michael R. Crusoe, Kristian Peters, and Daniel Schober FAIR Computational Workflows Data Intelligence 2020 2:1-2, 108-121 https://doi.org/10.1162/dint_a_00033.
FAIR Workflows and Research Objects get a Workout Carole Goble
So, you want to build a pan-national digital space for bioscience data and methods? That works with a bunch of pre-existing data repositories and processing platforms? So you can share FAIR workflows and move them between services? Package them up with data and other stuff (or just package up data for that matter)? How? WorkflowHub (https://workflowhub.eu) and RO-Crate Research Objects (https://www.researchobject.org/ro-crate) that’s how! A step towards FAIR Digital Objects gets a workout.
Presented at DataVerse Community Meeting 2021
FAIRy stories: the FAIR Data principles in theory and in practiceCarole Goble
https://ucsb.zoom.us/meeting/register/tZYod-ippz4pHtaJ0d3ERPIFy2QIvKqjwpXR
FAIRy stories: the FAIR Data principles in theory and in practice
The ‘FAIR Guiding Principles for scientific data management and stewardship’ [1] launched a global dialogue within research and policy communities and started a journey to wider accessibility and reusability of data and preparedness for automation-readiness (I am one of the army of authors). Over the past 5 years FAIR has become a movement, a mantra and a methodology for scientific research and increasingly in the commercial and public sector. FAIR is now part of NIH, European Commission and OECD policy. But just figuring out what the FAIR principles really mean and how we implement them has proved more challenging than one might have guessed. To quote the novelist Rick Riordan “Fairness does not mean everyone gets the same. Fairness means everyone gets what they need”.
As a data infrastructure wrangler I lead and participate in projects implementing forms of FAIR in pan-national European biomedical Research Infrastructures. We apply web-based industry-lead approaches like Schema.org; work with big pharma on specialised FAIRification pipelines for legacy data; promote FAIR by Design methodologies and platforms into the researcher lab; and expand the principles of FAIR beyond data to computational workflows and digital objects. Many use Linked Data approaches.
In this talk I’ll use some of these projects to shine some light on the FAIR movement. Spoiler alert: although there are technical issues, the greatest challenges are social. FAIR is a team sport. Knowledge Graphs play a role – not just as consumers of FAIR data but as active contributors. To paraphrase another novelist, “It is a truth universally acknowledged that a Knowledge Graph must be in want of FAIR data.”
[1] Wilkinson, M., Dumontier, M., Aalbersberg, I. et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 3, 160018 (2016). https://doi.org/10.1038/sdata.2016.18
RO-Crate: A framework for packaging research products into FAIR Research ObjectsCarole Goble
RO-Crate: A framework for packaging research products into FAIR Research Objects presented to Research Data Alliance RDA Data Fabric/GEDE FAIR Digital Object meeting. 2021-02-25
The swings and roundabouts of a decade of fun and games with Research Objects Carole Goble
Research Objects and their instantiation as RO-Crate: motivation, explanation, examples, history and lessons, and opportunities for scholarly communications, delivered virtually to 17th Italian Research Conference on Digital Libraries
How are we Faring with FAIR? (and what FAIR is not)Carole Goble
Keynote presented at the workshop FAIRe Data Infrastructures, 15 October 2020
https://www.gmds.de/aktivitaeten/medizinische-informatik/projektgruppenseiten/faire-dateninfrastrukturen-fuer-die-biomedizinische-informatik/workshop-2020/
Remarkably it was only in 2016 that the ‘FAIR Guiding Principles for scientific data management and stewardship’ appeared in Scientific Data. The paper was intended to launch a dialogue within the research and policy communities: to start a journey to wider accessibility and reusability of data and prepare for automation-readiness by supporting findability, accessibility, interoperability and reusability for machines. Many of the authors (including myself) came from biomedical and associated communities. The paper succeeded in its aim, at least at the policy, enterprise and professional data infrastructure level. Whether FAIR has impacted the researcher at the bench or bedside is open to doubt. It certainly inspired a great deal of activity, many projects, a lot of positioning of interests and raised awareness. COVID has injected impetus and urgency to the FAIR cause (good) and also highlighted its politicisation (not so good).
In this talk I’ll make some personal reflections on how we are faring with FAIR: as one of the original principles authors; as a participant in many current FAIR initiatives (particularly in the biomedical sector and for research objects other than data) and as a veteran of FAIR before we had the principles.
Developing Distributed High-performance Computing Capabilities of an Open Sci...Globus
COVID-19 had an unprecedented impact on scientific collaboration. The pandemic and its broad response from the scientific community has forged new relationships among public health practitioners, mathematical modelers, and scientific computing specialists, while revealing critical gaps in exploiting advanced computing systems to support urgent decision making. Informed by our team’s work in applying high-performance computing in support of public health decision makers during the COVID-19 pandemic, we present how Globus technologies are enabling the development of an open science platform for robust epidemic analysis, with the goal of collaborative, secure, distributed, on-demand, and fast time-to-solution analyses to support public health.
Enhancing Research Orchestration Capabilities at ORNL.pdfGlobus
Cross-facility research orchestration comes with ever-changing constraints regarding the availability and suitability of various compute and data resources. In short, a flexible data and processing fabric is needed to enable the dynamic redirection of data and compute tasks throughout the lifecycle of an experiment. In this talk, we illustrate how we easily leveraged Globus services to instrument the ACE research testbed at the Oak Ridge Leadership Computing Facility with flexible data and task orchestration capabilities.
Atelier - Innover avec l’IA Générative et les graphes de connaissancesNeo4j
Atelier - Innover avec l’IA Générative et les graphes de connaissances
Allez au-delà du battage médiatique autour de l’IA et découvrez des techniques pratiques pour utiliser l’IA de manière responsable à travers les données de votre organisation. Explorez comment utiliser les graphes de connaissances pour augmenter la précision, la transparence et la capacité d’explication dans les systèmes d’IA générative. Vous partirez avec une expérience pratique combinant les relations entre les données et les LLM pour apporter du contexte spécifique à votre domaine et améliorer votre raisonnement.
Amenez votre ordinateur portable et nous vous guiderons sur la mise en place de votre propre pile d’IA générative, en vous fournissant des exemples pratiques et codés pour démarrer en quelques minutes.
How Recreation Management Software Can Streamline Your Operations.pptxwottaspaceseo
Recreation management software streamlines operations by automating key tasks such as scheduling, registration, and payment processing, reducing manual workload and errors. It provides centralized management of facilities, classes, and events, ensuring efficient resource allocation and facility usage. The software offers user-friendly online portals for easy access to bookings and program information, enhancing customer experience. Real-time reporting and data analytics deliver insights into attendance and preferences, aiding in strategic decision-making. Additionally, effective communication tools keep participants and staff informed with timely updates. Overall, recreation management software enhances efficiency, improves service delivery, and boosts customer satisfaction.
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(2) SocioWave Review: https://sumonreview.com/sociowave-review
(3) AI Partner & Profit Review: https://sumonreview.com/ai-partner-profit-review
(4) AI Ebook Suite Review: https://sumonreview.com/ai-ebook-suite-review
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Globus Connect Server Deep Dive - GlobusWorld 2024Globus
We explore the Globus Connect Server (GCS) architecture and experiment with advanced configuration options and use cases. This content is targeted at system administrators who are familiar with GCS and currently operate—or are planning to operate—broader deployments at their institution.
How to Position Your Globus Data Portal for Success Ten Good PracticesGlobus
Science gateways allow science and engineering communities to access shared data, software, computing services, and instruments. Science gateways have gained a lot of traction in the last twenty years, as evidenced by projects such as the Science Gateways Community Institute (SGCI) and the Center of Excellence on Science Gateways (SGX3) in the US, The Australian Research Data Commons (ARDC) and its platforms in Australia, and the projects around Virtual Research Environments in Europe. A few mature frameworks have evolved with their different strengths and foci and have been taken up by a larger community such as the Globus Data Portal, Hubzero, Tapis, and Galaxy. However, even when gateways are built on successful frameworks, they continue to face the challenges of ongoing maintenance costs and how to meet the ever-expanding needs of the community they serve with enhanced features. It is not uncommon that gateways with compelling use cases are nonetheless unable to get past the prototype phase and become a full production service, or if they do, they don't survive more than a couple of years. While there is no guaranteed pathway to success, it seems likely that for any gateway there is a need for a strong community and/or solid funding streams to create and sustain its success. With over twenty years of examples to draw from, this presentation goes into detail for ten factors common to successful and enduring gateways that effectively serve as best practices for any new or developing gateway.
Quarkus Hidden and Forbidden ExtensionsMax Andersen
Quarkus has a vast extension ecosystem and is known for its subsonic and subatomic feature set. Some of these features are not as well known, and some extensions are less talked about, but that does not make them less interesting - quite the opposite.
Come join this talk to see some tips and tricks for using Quarkus and some of the lesser known features, extensions and development techniques.
A Study of Variable-Role-based Feature Enrichment in Neural Models of CodeAftab Hussain
Understanding variable roles in code has been found to be helpful by students
in learning programming -- could variable roles help deep neural models in
performing coding tasks? We do an exploratory study.
- These are slides of the talk given at InteNSE'23: The 1st International Workshop on Interpretability and Robustness in Neural Software Engineering, co-located with the 45th International Conference on Software Engineering, ICSE 2023, Melbourne Australia
In 2015, I used to write extensions for Joomla, WordPress, phpBB3, etc and I ...Juraj Vysvader
In 2015, I used to write extensions for Joomla, WordPress, phpBB3, etc and I didn't get rich from it but it did have 63K downloads (powered possible tens of thousands of websites).
Top 7 Unique WhatsApp API Benefits | Saudi ArabiaYara Milbes
Discover the transformative power of the WhatsApp API in our latest SlideShare presentation, "Top 7 Unique WhatsApp API Benefits." In today's fast-paced digital era, effective communication is crucial for both personal and professional success. Whether you're a small business looking to enhance customer interactions or an individual seeking seamless communication with loved ones, the WhatsApp API offers robust capabilities that can significantly elevate your experience.
In this presentation, we delve into the top 7 distinctive benefits of the WhatsApp API, provided by the leading WhatsApp API service provider in Saudi Arabia. Learn how to streamline customer support, automate notifications, leverage rich media messaging, run scalable marketing campaigns, integrate secure payments, synchronize with CRM systems, and ensure enhanced security and privacy.
Large Language Models and the End of ProgrammingMatt Welsh
Talk by Matt Welsh at Craft Conference 2024 on the impact that Large Language Models will have on the future of software development. In this talk, I discuss the ways in which LLMs will impact the software industry, from replacing human software developers with AI, to replacing conventional software with models that perform reasoning, computation, and problem-solving.
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https://sumonreview.com/ai-pilot-review/
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(1) TubeTrivia AI Review: https://sumonreview.com/tubetrivia-ai-review
(2) SocioWave Review: https://sumonreview.com/sociowave-review
(3) AI Partner & Profit Review: https://sumonreview.com/ai-partner-profit-review
(4) AI Ebook Suite Review: https://sumonreview.com/ai-ebook-suite-review
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BoxLang is more than just a language; it's a community. By choosing a Visionary License, you're not just investing in your success, you're actively contributing to the ongoing development and support of BoxLang.
Gamify Your Mind; The Secret Sauce to Delivering Success, Continuously Improv...Shahin Sheidaei
Games are powerful teaching tools, fostering hands-on engagement and fun. But they require careful consideration to succeed. Join me to explore factors in running and selecting games, ensuring they serve as effective teaching tools. Learn to maintain focus on learning objectives while playing, and how to measure the ROI of gaming in education. Discover strategies for pitching gaming to leadership. This session offers insights, tips, and examples for coaches, team leads, and enterprise leaders seeking to teach from simple to complex concepts.
Introducing Crescat - Event Management Software for Venues, Festivals and Eve...Crescat
Crescat is industry-trusted event management software, built by event professionals for event professionals. Founded in 2017, we have three key products tailored for the live event industry.
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Top Features to Include in Your Winzo Clone App for Business Growth (4).pptx
SEEK for Science: A Data and Model Management Platform to support Open and Reproducible Science in Systems Biology
1. SEEK for Science:
A Data Management Platform
to support Open and
Reproducible Science
Professor Carole Goble
The University of Manchester
UK
BOSC 2014, 12th July 2014
3. Sponsors and Motivation
• BMBF “Großprojekt“
• ~45 organisations
• ~70 groups
• multiscale rep of the liver
• multiscale data, models
• imaging data
• EU ERANet programme
• 122 organisations
• 16 multi-inst. consortia
• independent projects in a
two-round funding initiative
4. Funders
• Preserve results beyond projects.
• Organise & link data, models,
processes.
• Exchange & search initiative‘s
assets.
• Share & disseminate results
• Improve standard curation
practice.
• Pool capacities.
• Handle home-brewed solutions
with mixed resourcing and no
access
5. People
• Dynamic distributed groups of
experimentalists and modellers
• Cherished own home-grown
and unstable data solutions
– wikis, CMS, databases,
spreadsheets, files.
• Access & visibility control over
shared content
6. Content
• Locally hosted private repositories
• Public archives
• From single-cell to human
• Samples, Specimens, Standard Op
Procedures
• Small Data: Reactome…: files,
spreadsheets
• Big Data: NGS, Mass Spec…:
Specialist repositories, files
• Models: ODE, SBML, Native Matlab,
PDE, Multi-scale
• In progress: versioning, track provenance and parameters
• Published: citation, links to publications
7. Cataloguing
7
Find my peers
Creating and sharing
SOPs across projects
Track my
specimens
yellow pages, manage SOPs and link them to investigations, studies, assays,
specimens and samples
Browse experimental data without
downloading them
How data, models and SOPs fit
together
Which data belong to which
publication
Data viewing functionality
ISA: Link Studies to their data, models,
SOPs, samples, publications
Track different
versions of my
model
8. The Web-based SEEK Platform
Ruby on RAILS 3.2, BSD,
https://bitbucket.org/seek4science/seek
https://seek.sysmo-db.org/models/114
http://www.seek4science.org
10. simulate models
project mgt,
access control
reporting, citation
governance &
policies
yellow pages
of peers
projects,
experts
catalogue, link and
index data, models,
samples, specimens,
sops, experiments,
publications using
standards
curate &
annotate data
and models using
standards with
compliance tools
incorporate public
data and model
repositories & tools
deposition
manage, store and
exchange different
types and scales of
data
Reproducibility Score Card
integrate local and
project tools and
data systems
scaled-out
collection &
analytics using third
party platforms
differentiate
construction,
validation &
predicted data
11. Yellow Pages InstitutionsProjectsPeople
ISA
Investigation
Study
Assay
Asset Catalogue
Models
Datafiles
SOPs
Publications
TagsVersions
Access Privileges
PresentationsEvents
Datafiles Models SOPs
JERMExtract,Harvest,Index
APIsandLinks
BioModels
CheBI
BioPortal
PubMed
JWS Online
GEO
SABIO-RK
Web Interface REST API
Local SEEK
Wikis
CMS
Own DB
Direct Upload
Project DM External
SEEK
OpenBIS
12. • Gateway plugin framework
– Tight and loose coupling
– RAILS plugin or bundled GEM
• Metadata framework
– JERM and ISA
• Different instances
– Single query across all model
repositories
– One click deposition
BioModels
Plug-in, Play nice, Don’t reinvent
13. Data….
• Public and new data
• Factors studied
– Linked -> SABIO-RK and ChEBI
• Samples and Specimens
– Extends EBI/NCBI BioSamples
• Treatment Extraction
• Tagging with vocabularies
• Spreadsheet-based data-view
• Big Data
– Upload and by email, Share by
trusted link, Link to external
repository
• Access
– DOIs and Temp links for reviews
14. Cytoscape
Repositories
• Biomodels, JWS Online,
local SEEK
JWS Online Simulator
• SBML support
• Auto generation of SBGN
schemas for user models
• SED-ML export
DataFuse
• Link and compare
construction and validation
data with models
• Run models with
parameter values from
spreadsheets
Models….
16. Standards, Structure, Interlink
Construction Validation
Metabolomics
Metabolomics
Mass
SpecTranscriptomics
Proteomics
Fluxomics
Investigations
Studies
Assays
Towards Interoperable
Bioscience Data, Nature
Genetics, 2012
Assays
17.
18.
19.
20. Just Enough
Results Model
Describes and
enriches the
relationships
between things
produced and
used in
experiments.
http://bioportal.bioontology.org/ontologies/JERM
reuse
community
ontologies,
markups, mim,
identifiers
21. metadata sheets
sample sheets
data sheets
indexes
http://rightfield.org.uk/
Just Enough
Results Model
Describes and
enriches the
relationships
between things
produced and
used in
experiments.
http://bioportal.bioontology.org/ontologies/JERM
reuse
community
ontologies,
markups, mim,
identifiers
22. Different types of data
Plugins to registered
data repositories
Extract and
auto-
catalogue
metadata
Define
relationships,
cross-link,
aggregate, query
standard based
templates
non-standard
templates
Open Modelling
Exchange Format
archive
23. Sys Bio Research Objects
portable packaged research
Adobe UCF
Research Object
Bundle
ORE PROVODF
• Aggregation
• Annotations/provenance
• Ad-hoc domain-specific
specification
OMEX archive
Systems Biology:
A common archive
format for reuse across
tools
http://www.researchobject.org
25. Open Research: Research Groups & Lifecycles
• Sharing policy
• Visibility, Downloadability
• Fine grained permissions
• Protocols for
– Management transfer
– Visibility feedback and sharing
workflows
– Publication data deposition in
external public stores
– Batch publishing
Within Project
Versions
Retractions
Across Projects
Versions
Public
Final version
No Retraction
Manager
Owner
Gatekeeper
28. Open Facility for European Systems
Biology data & model management
seeded by EU programmes
• Platform
– SEEK + openBIS + new features & styling
• Resource
– EuroSEEK + pool of community resources
(including established SEEKs).
– Independent researchers. Secure data.
• Facility
– Curation & support services, training
http://fair-dom.org/
29. Open Facility for European Systems
Biology data & model management
seeded by EU programmes
• Community
– workshops, user and developer forums,
knowledge network, standards & policy,
training, FAIRDOM Foundation, Model
Carpentry.
• Sys Bio Developers Foundry workshop
6-7 October Heidelberg
http://fair-dom.org/wiki/Foundry_workshop
• RI
– working with other EU RIs, an EU network of
national facilities, funding models.
http://fair-dom.org/