The heart receives its blood supply from two coronary arteries - the right and left coronary arteries. These branch directly off the aorta. The right coronary artery supplies the right atrium and ventricle as well as parts of the left ventricle and septum. The left coronary artery is larger and supplies the left atrium and ventricle as well as parts of the right ventricle. Blood is drained from the heart by the coronary sinus and smaller cardiac veins which drain into the right atrium. The lymphatic vessels accompany the coronary arteries and drain into nearby lymph nodes. Diseases like angina and myocardial infarction occur when the coronary arteries become narrowed or blocked, reducing blood supply to parts of the heart.
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Anatomy And Physiology of Human Heart
1. ANATOMY OF THE HEART By: Dr Mohammed Faez
2. The Heart The heart is a chambered muscular organ that pumps blood received from the veins into the arteries, thereby maintaining the flow of blood through the entire circulatory system.
3. The Heart • The heart is surrounded by membrane called Pericardium.
4. The Pericardium • The pericardium is a fibroserous sac that encloses the heart and the roots of the great vessels. • The pericardium lies within the middle mediastinum.
5. The Pericardium
6. The Pericardium • Its function is to restrict excessive movements of the heart as a whole and to serve as a lubricated container in which the different parts of the heart can contract.
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Anatomy And Physiology of Human Heart
1. ANATOMY OF THE HEART By: Dr Mohammed Faez
2. The Heart The heart is a chambered muscular organ that pumps blood received from the veins into the arteries, thereby maintaining the flow of blood through the entire circulatory system.
3. The Heart • The heart is surrounded by membrane called Pericardium.
4. The Pericardium • The pericardium is a fibroserous sac that encloses the heart and the roots of the great vessels. • The pericardium lies within the middle mediastinum.
5. The Pericardium
6. The Pericardium • Its function is to restrict excessive movements of the heart as a whole and to serve as a lubricated container in which the different parts of the heart can contract.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
5. • The heart receives its own supply of blood from the
coronary arteries.
• Two major coronary arteries branch off from the aorta
near the point where the aorta and the left ventricle meet.
These arteries and their branches supply all parts of the
heart muscle with blood.
6. RIGHT CORONARY
ARTERY
• Smaller than left coronary artery.
• Arises from anterior coronary sinus
Course:
Emerges from the surface of the heart between pulmonary trunk
and right auricle.
Winds around the inferior border to reach the diaphragmatic
surface to reach the posterior interior – ventricular groove.
Terminates by anastomosing with left coronary artery.
7.
8. • Branches of the Right Coronary Artery
• Large Branches
Marginal
Post – Interventricular
• Small Branches
Right arterial
Infundibular
Nodal
Terminal
9. • Areas of Distribution
• Right Atrium
• Ventricles
• Greater part of right ventricle.
• Small part of left ventricle.
• Posterior part of the inter – ventricular
septum.
• Whole of the conducting system of the heart
except a part of the left branch of AV bundle.
The SA node is supplied by left – coronary
artery in 40% cases.
11. • Course:
• Runs forward and to the left and emerges between the
pulmonary trunk and the left auricle.
• Here the anterior inter-ventricular branch is given.
• The further continuation of the left coronary artery is
sometimes called the circumflex artery.
• After giving off the anterior inter-ventricular branch it
runs into the left anterior coronary sulcus.
• In winds around the left border and near posterior inter-
ventricular groove . It terminates by anastomosing with the
right coronary artery.
12. • Branches:
• Large Branches:
• Anterior Interventricular
• Branch to the diaphragmatic surface of the left ventricle.
• Small Branches:
• Left Atrial
• Pulmonary
• Terminal
13. • Areas of Distribution
• Left atrium
• Ventricles
• Greater part of the left ventricle, except the area adjoining
the posterior inter-ventricular groove.
• A small part of the right ventricle adjoining the anterior
inter-ventricular groove.
• Anterior part of the inter-ventricular septum.
• Part of left branch AV bundle.
14. COLLATERAL
CIRCULATION
• Cardiac Anastomosis: the two coronary artery anastomose to the
myocardium.
• Extra Cardiac Anastomosis: the cardiac arteries anastomosis with
other organ’s arteries.
• Vasa Vasorum of the aorta
• Vasa Vasorum of the pulmonary arteries
• Internal thoracic arteries
• The bronchial arteries
• Phrenic arteries
• These channels open up in the emergencies when the coronary
arteries are blocked.
15. CORONARY ARTERY
DOMINANCE
• The artery that gives the posterior inter-ventricular
artery determines the coronary dominance.
• RCA (Right Coronary Artery)
• CX (Circumflex Artery)
16. VENOUS DRAINAGE
•The venous drainage of the heart is
by 3 ways
•A. Coronary Sinus
•Anterior Cardiac Veins
•Venae Cordis Minimae
17. • Coronary Sinus – this is the largest vein of the heart
situates in the left posterior coronary sulcus. It is about 3
cm long and ends by opening into the posterior wall of the
right atrium.
• Its Branches are
• Great Cardiac Vein – it enter the left end of the coronary
sinus.
• Middle Cardiac Vein – it accompanies the posterior inter-
ventricular artery and joins the right end of the coronary
sinus.
• Small Cardiac Veins – it accompanies the right coronary
artery and joins the right end of the coronary sinus.
18. • Posterior vein of Left Ventricle: it runs on the
diaphragmatic surface of the left atrium and ends in the
middle of the coronary sinus.
• Oblique vein of the left atrium – it runs on the posterior
surface of the left atrium , joins the left end of coronary
sinus and develops from the left common cardinal veins.
• The right marginal veins – it accompanies the marginal
branch of the right coronary artery.
19. • ANTERIOR CARDIAC VEINS – 3 – 4 small veins run on
the anterior wall of the right ventricle, open directly into
the right atrium.
• VENAE CORDIS MINIMAE
• Numerous small veins present in all 4 chambers of the
heart which opens directly into the cavities.
• The thebesian venous network is considered as an
alternative pathway for venous drainage of the
myocardium.
20. LYMPHATIC NETWORK
• It accompanies the coronary artery and form 2 trunks.
• Rt trunk ends in bracheocephalic nodes and the left trunk
into the tracheobronchial lymph nodes at the bifurcation of
the trachea.
21. Applied Anatomy
• Angina Pectoris – Severe chest pain due to ischaemia of the
heart.
• Angina pectoris is due to the narrowing of the arteries.
• Myocardial Infarction - it means necrosis of a part the
myocardium due to severe prolonged ischaemia due to ischaemia
of coronary arteriies.
• Occlusion of the one of the coronary arteries or its branches.