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BIOTECHNOLOGY
Speaker:
Ananda Kumar Saha
Department of Zoology, R.U.
Biotechnology: The development and
utilization of biological processes for
obtaining maximum benefits to man
and other forms of life.
Biotechnology: The use of living
organisms for the manufacture of
useful products: It may involve algae,
bacteria, fungi, yeast cells of higher
animal and plants.
BIOTECHNOLOGY
 Genetic Engineering: The formation of new
combinations of heritable material by the
insertion of nucleic acid molecules into any
virus, bacterial plasmids or other vector
system so as to allow their incorporation into a
host organism in which they do not naturally
occur but in which they are capable of
continued propagation (Smith, 1996).
 Genetic Engineering is the production of new
genes and alteration of genomes by
substituting or adding new genetic material.
GENETIC ENGINEERING
 Traditional Biotechnology (Old)
 New Biotechnology (Modern)
 Traditional Biotechnology: The Traditional
biotechnology refers to the conventional
technology which have been used for many
centuries. Beer, Wine, Cheese and many foods
have been produced using traditional
biotechnology.
HISTORY OF BIOTECHNOLOGY
 The Traditional biotechnology is an art rather
than a science.
 Modern Biotechnology: Capability of science
to change the genetic material for genetic new
products for specific requirement through
recombinant DNA technology.
HISTORY OF BIOTECHNOLOGY (contd.)
Application of Biotechnology
SCOPE OF BIOTECHNOLOGY
1. Health care:
(a) In 1982, human insulin (humulin) has been
produced by microorganisms in fermenters.
(b) Hepatitis B vaccines (Recombivax HB),
genetically engineered vaccines produced
biotechnologically.
2. Gene Therapy: This is in a way, genetic
engineering of humans, which would allow a
person suffering from a disabling genetic
disorder to lead a normal life.
3. Immunotechnologies: Monoclonal antibodies
(MABs) for diagnosis and therapy. Antibodies,
special sets of proteins present in humans that
enable them to fight incursion of their bodies by
harmful chemicals or microorganisms.
SCOPE OF BIOTECHNOLOGY (contd.)
Gene therapy
Gene Therapy
Gene Therapy
4. Tissue culture: Tissue culture of both plant
and animal cells. These are used for
Micropropagation of elite or exotic materials
(such as orchids), production of useful
compounds such as taxol (the widely used anti-
cancer drug) and vanillin, and preparation in the
laboratory of “natural” tissues such as arteries
for arterial graft or skin for burn victims.
SCOPE OF BIOTECHNOLOGY (contd.)
5. Stem cell techniques: Which would involve
purification and isolation of stem cells from
various tissues and develop into the desired
tissue which could then be used, for example,
for transplantation.
6. New DNA technologies: These include DNA
fingerprinting, sequencing of genomes,
development and use of new molecular markers
for plant identification and characterization.
SCOPE OF BIOTECHNOLOGY (contd.)
Stem Cell
Stem Cell Therapy
7. Organotransplantation: Xenotransplantation
that is transplantation into humans of organs
from other animals. It appears that pig may be the
most suitable for this biochemically, anatomically
and immunologically.
8. Bioremediation: Bioremediation is the use of
microorganisms to detoxify pollutants, present in
the environment usually as soil or water
sediments.
SCOPE OF BIOTECHNOLOGY (contd.)
Bioremediation
9. Human Genome Project (HGP): Human
genome has been sequenced and chromosome
map has been developed in various laboratories
world-wide through coordinated efforts.
10. Bioinformatics: Application of information
sciences to increase the understanding of biology,
biochemistry and biological data.
SCOPE OF BIOTECHNOLOGY (contd.)
Thank you

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Biotechnology_Prof.-A.K.Saha_.ppt

  • 1.
  • 3. Biotechnology: The development and utilization of biological processes for obtaining maximum benefits to man and other forms of life. Biotechnology: The use of living organisms for the manufacture of useful products: It may involve algae, bacteria, fungi, yeast cells of higher animal and plants. BIOTECHNOLOGY
  • 4.  Genetic Engineering: The formation of new combinations of heritable material by the insertion of nucleic acid molecules into any virus, bacterial plasmids or other vector system so as to allow their incorporation into a host organism in which they do not naturally occur but in which they are capable of continued propagation (Smith, 1996).  Genetic Engineering is the production of new genes and alteration of genomes by substituting or adding new genetic material. GENETIC ENGINEERING
  • 5.  Traditional Biotechnology (Old)  New Biotechnology (Modern)  Traditional Biotechnology: The Traditional biotechnology refers to the conventional technology which have been used for many centuries. Beer, Wine, Cheese and many foods have been produced using traditional biotechnology. HISTORY OF BIOTECHNOLOGY
  • 6.  The Traditional biotechnology is an art rather than a science.  Modern Biotechnology: Capability of science to change the genetic material for genetic new products for specific requirement through recombinant DNA technology. HISTORY OF BIOTECHNOLOGY (contd.)
  • 8. SCOPE OF BIOTECHNOLOGY 1. Health care: (a) In 1982, human insulin (humulin) has been produced by microorganisms in fermenters. (b) Hepatitis B vaccines (Recombivax HB), genetically engineered vaccines produced biotechnologically.
  • 9. 2. Gene Therapy: This is in a way, genetic engineering of humans, which would allow a person suffering from a disabling genetic disorder to lead a normal life. 3. Immunotechnologies: Monoclonal antibodies (MABs) for diagnosis and therapy. Antibodies, special sets of proteins present in humans that enable them to fight incursion of their bodies by harmful chemicals or microorganisms. SCOPE OF BIOTECHNOLOGY (contd.)
  • 13. 4. Tissue culture: Tissue culture of both plant and animal cells. These are used for Micropropagation of elite or exotic materials (such as orchids), production of useful compounds such as taxol (the widely used anti- cancer drug) and vanillin, and preparation in the laboratory of “natural” tissues such as arteries for arterial graft or skin for burn victims. SCOPE OF BIOTECHNOLOGY (contd.)
  • 14. 5. Stem cell techniques: Which would involve purification and isolation of stem cells from various tissues and develop into the desired tissue which could then be used, for example, for transplantation. 6. New DNA technologies: These include DNA fingerprinting, sequencing of genomes, development and use of new molecular markers for plant identification and characterization. SCOPE OF BIOTECHNOLOGY (contd.)
  • 17. 7. Organotransplantation: Xenotransplantation that is transplantation into humans of organs from other animals. It appears that pig may be the most suitable for this biochemically, anatomically and immunologically. 8. Bioremediation: Bioremediation is the use of microorganisms to detoxify pollutants, present in the environment usually as soil or water sediments. SCOPE OF BIOTECHNOLOGY (contd.)
  • 19. 9. Human Genome Project (HGP): Human genome has been sequenced and chromosome map has been developed in various laboratories world-wide through coordinated efforts. 10. Bioinformatics: Application of information sciences to increase the understanding of biology, biochemistry and biological data. SCOPE OF BIOTECHNOLOGY (contd.)