The document discusses partnerships in drug discovery for diseases that primarily impact developing countries. It focuses on the importance of partnerships like the TB Drug Accelerator (TBDA) in developing new treatments for tuberculosis. The TBDA is a partnership between pharmaceutical companies and research institutions that aims to develop a new one-month drug regimen for TB through open data sharing, collaborative research, and ensuring the best candidates advance. Such partnerships are a new paradigm that can help address bottlenecks in developing new TB drugs and serve as a model for other disease areas.
4 Forthcoming Funding Opportunities
1
Elton John AIDS Foundation (EJAF)
Is accepting grant applications
To create an AIDS free future for everybody in this world
Deadline: September 12, 2015
2
Global Fund for Women
Will be accepting Organizational Profiles from women or women-led organizations for the grant that will advance human rights of women and girls to strengthen women-led groups based outside the United States beginning
September 1, 2015
3
The Pacific Asia Travel Association (PATA) foundation
Is accepting grant applications to
Protect Environment, Cultural heritage and Wildlife across Asia
The submission deadline is August 10, 2015
4
Red Umbrella Fund
Is accepting grant applications for
Promoting sex worker’s human rights, building sex worker’s capacities and strengthening and sustaining the sex worker’s rights movement.
Deadline: August 3, 2015
We surveyed leaders and managers of ILIs in 33 African countries to provide the first region-wide portrait of contexts, motivations, design, participation and outcomes of such initiatives. Results suggest that ILIs are promoting “multi-functionality” of rural regions, while aiding stakeholders in negotiating trade-offs and synergies among multiple outcomes.
Proposed Int' Relief Organization Template to address socio-economic challenges and improving livelihoods of individuals, communities and regions as a whole.
4 Forthcoming Funding Opportunities
1
Elton John AIDS Foundation (EJAF)
Is accepting grant applications
To create an AIDS free future for everybody in this world
Deadline: September 12, 2015
2
Global Fund for Women
Will be accepting Organizational Profiles from women or women-led organizations for the grant that will advance human rights of women and girls to strengthen women-led groups based outside the United States beginning
September 1, 2015
3
The Pacific Asia Travel Association (PATA) foundation
Is accepting grant applications to
Protect Environment, Cultural heritage and Wildlife across Asia
The submission deadline is August 10, 2015
4
Red Umbrella Fund
Is accepting grant applications for
Promoting sex worker’s human rights, building sex worker’s capacities and strengthening and sustaining the sex worker’s rights movement.
Deadline: August 3, 2015
We surveyed leaders and managers of ILIs in 33 African countries to provide the first region-wide portrait of contexts, motivations, design, participation and outcomes of such initiatives. Results suggest that ILIs are promoting “multi-functionality” of rural regions, while aiding stakeholders in negotiating trade-offs and synergies among multiple outcomes.
Proposed Int' Relief Organization Template to address socio-economic challenges and improving livelihoods of individuals, communities and regions as a whole.
A short 5-minute presentation on how microfinancing is bringing people out of poverty in the developing world, using Kiva as a case study, written for Ignite Liverpool 15, 15th August 2013
USAID's Dianna Lightfoot explores examples of successful faith-based organization partnerships with USAID and shares resources to help organizations partner with USAID.
Rotary Continues Funding Fight against Polio WorldwidePeter Killcommons
Physician and philanthropist Dr. Peter “Pete” Killcommons is the founder and currently serves as CEO of Medweb, a company that specializes in mobile medical technologies that help patients get medical attention in developing countries throughout the world. Outside of his professional life, Dr. Peter “Pete” Killcommons is a member of Rotary International.
Asian Development Bank Outlook (ADO) 2019 updateMYO AUNG Myanmar
Asian Development Bank Outlook (ADO) 2019 Update: Fostering Growth and Inclusion in Asia's Cities
https://www.adb.org/publications/asian-development-outlook-2019-update
Asian Development Outlook (ADO) 2019 Update: Fostering Growth and Inclusion in Asia's Cities
Publication | September 2019
While food waste and loss is a global problem, YieldWise focuses on sub-Saharan Africa, where 70 percent of the people rely on agriculture for their livelihoods and many of whom are also part of the world's 1.3 billion who are food insecure. Here, 50 percent of fruits and vegetables, 40 percent of roots and tubers, and 20 percent of cereals—all of which are staple foods—are lost in the post-harvest stage or processes. As such, these vulnerable people are twice-hit.
Hands on Manila Foundation, Inc. is a volunteer non-profit based in Manila, Philippines. We customize CSR programs for corporations and develop community initiatives for whoever wants to volunteer.
While the majority of the African population is heavily reliant on agriculture, the continent has lagged behind other developing regions in progressing this essential sector. Research and development specific to the continent’s varied ecosystems and crops has been chronically neglected, as has infrastructure and education to support farmers. As Harvard professor and Kenyan national Calestous Juma has argued: “Neglect of agriculture has been a defining feature of Africa’s economic policy over the last four decades.”
The Global Agriculture and Food Security ProgramFrancois Stepman
4 October 2017. InfoPoint Lunchtime conference: Global Agriculture and Food Security Programme.
The presentation provided an overview of the Global Agriculture and Food Security Program (GAFSP), a funding mechanism that supports underfunded country-led efforts to end hunger and poverty, and has provided over $1.2 billion in grant funding to public sector investments, $250 million in innovative financing for complementary private sector investments, and $13 million to pilot projects reaching smallholder farmers more directly.
Presentation:
Nichola Dyer: Program Manager, Global Agriculture and Food Security Program (GAFSP)
This synthesis review of key factors supporting small-scale coastal fisheries management was commissioned by the Rockefeller Foundation through a contract with Itad Ltd. The work was carried out by a team based at IMM Ltd, in Exeter, UK, from July to September 2013.
It was designed to provide an evidence base on the success factors in small-scale coastal fisheries management in developing countries and, in turn, to assist the Rockefeller Foundation in developing its strategy for its Oceans and Fisheries Initiative. In doing so, it identifies and describes some 20 key factors believed to influence success in small-scale coastal fisheries management.
The synthesis first presents an outline of the methods used in the study followed by a background of coastal fisheries, an introduction to fisheries management themes, and a review and discussion of some of the critical factors that influence success. It then offers some conclusions and possible ways forward.
A short 5-minute presentation on how microfinancing is bringing people out of poverty in the developing world, using Kiva as a case study, written for Ignite Liverpool 15, 15th August 2013
USAID's Dianna Lightfoot explores examples of successful faith-based organization partnerships with USAID and shares resources to help organizations partner with USAID.
Rotary Continues Funding Fight against Polio WorldwidePeter Killcommons
Physician and philanthropist Dr. Peter “Pete” Killcommons is the founder and currently serves as CEO of Medweb, a company that specializes in mobile medical technologies that help patients get medical attention in developing countries throughout the world. Outside of his professional life, Dr. Peter “Pete” Killcommons is a member of Rotary International.
Asian Development Bank Outlook (ADO) 2019 updateMYO AUNG Myanmar
Asian Development Bank Outlook (ADO) 2019 Update: Fostering Growth and Inclusion in Asia's Cities
https://www.adb.org/publications/asian-development-outlook-2019-update
Asian Development Outlook (ADO) 2019 Update: Fostering Growth and Inclusion in Asia's Cities
Publication | September 2019
While food waste and loss is a global problem, YieldWise focuses on sub-Saharan Africa, where 70 percent of the people rely on agriculture for their livelihoods and many of whom are also part of the world's 1.3 billion who are food insecure. Here, 50 percent of fruits and vegetables, 40 percent of roots and tubers, and 20 percent of cereals—all of which are staple foods—are lost in the post-harvest stage or processes. As such, these vulnerable people are twice-hit.
Hands on Manila Foundation, Inc. is a volunteer non-profit based in Manila, Philippines. We customize CSR programs for corporations and develop community initiatives for whoever wants to volunteer.
While the majority of the African population is heavily reliant on agriculture, the continent has lagged behind other developing regions in progressing this essential sector. Research and development specific to the continent’s varied ecosystems and crops has been chronically neglected, as has infrastructure and education to support farmers. As Harvard professor and Kenyan national Calestous Juma has argued: “Neglect of agriculture has been a defining feature of Africa’s economic policy over the last four decades.”
The Global Agriculture and Food Security ProgramFrancois Stepman
4 October 2017. InfoPoint Lunchtime conference: Global Agriculture and Food Security Programme.
The presentation provided an overview of the Global Agriculture and Food Security Program (GAFSP), a funding mechanism that supports underfunded country-led efforts to end hunger and poverty, and has provided over $1.2 billion in grant funding to public sector investments, $250 million in innovative financing for complementary private sector investments, and $13 million to pilot projects reaching smallholder farmers more directly.
Presentation:
Nichola Dyer: Program Manager, Global Agriculture and Food Security Program (GAFSP)
This synthesis review of key factors supporting small-scale coastal fisheries management was commissioned by the Rockefeller Foundation through a contract with Itad Ltd. The work was carried out by a team based at IMM Ltd, in Exeter, UK, from July to September 2013.
It was designed to provide an evidence base on the success factors in small-scale coastal fisheries management in developing countries and, in turn, to assist the Rockefeller Foundation in developing its strategy for its Oceans and Fisheries Initiative. In doing so, it identifies and describes some 20 key factors believed to influence success in small-scale coastal fisheries management.
The synthesis first presents an outline of the methods used in the study followed by a background of coastal fisheries, an introduction to fisheries management themes, and a review and discussion of some of the critical factors that influence success. It then offers some conclusions and possible ways forward.
How Oxfam India partnered with SocialCops to assess the state of Indian education across 1.4 million schools and promote awareness around the gaps in implementing the Right to Education Act.
Case Study: SocialCops + Bill & Melinda Gates FoundationSocialCops
How the Gates Foundation partnered with SocialCops to effectively invest $8 million in reducing extreme poverty for small and marginal farmers in rural India
Working in Global HealthChapter 18Chapter 18 Working irosacrosdale
Working in Global Health
Chapter 18
Chapter 18: Working in Global Health
1
Positions in Global Health
Universities
NGOs
Social entrepreneurships
Bilateral and multilateral aid organizations
Consulting
Global health is a growing field and there are many opportunities to work in it.
2
When considering a job in Global health
Understand the skills, knowledge, and experience this type of career would entail and how you might fill gaps you have in terms of the required background for a position.
May require a good understanding of economic development.
Should appreciate cultures.
Have the ability to write and speak well.
Be willing to live and work in low and middle income countries.
If you are considering a job in global health, you should: Understand the skills, knowledge, and experience this type of career would entail and how you might fill gaps you have in terms of the required background for a position.
May require a good understanding of economic development.
Should appreciate cultures.
Have the ability to write and speak well.
Be willing to live and work in low and middle income countries.
3
Other valuable points
Get your degree in an area related to the one in which you want to work.
Build on that area through internships, fellowships, and other opportunities to live and work abroad.
Consider a graduate program to build in your studies and experiences.
Work with mentors who work directly in the field.
Other things to consider are: Get your degree in an area related to the one in which you want to work.
Build on that area through internships, fellowships, and other opportunities to live and work abroad.
Consider a graduate program to build in your studies and experiences.
Work with mentors who work directly in the field.
4
Resources for careers
DEVEX http://globalhealth.org/
The Global Health Council http://globalhealth.org/
Global Health Hub www.globalhealthhub.org
International Jobs Center http://www.internationaljobs.org/
Idealist www.idealist.org
U.S Government
USAID https://www.usaid.gov/
CDC http://www.cdc.gov/
Here are a few resources to consider when looking for a career in global health.
5
Personal Quote
“Working in global health has been my dream as long as I can remember. And just imagine how reality could be better than a dream- and that’s exactly how I feel working in this field. It’s the most fulfilling career that I could ever imagine.”
Dr. Tara Rava Zolnikov
Assistant Professor
National University
Water project in Narok, Kenya
HIV/AIDS project in Busia, Kenya
Access to water research in Kitui, Kenya
Science, Technology, and Global Health
Chapter 17
1
Chapter 17: Science, Technology, and Global Health
The Need for New Products
Characteristics of new technologies must reflect the following:
Most important target groups are poor people.
Quality of care and injection safety is often low.
Many low- and middle-income countries have poorly organized health systems.
Science and technology ...
Analysis of drivers that cause restricted access to funding for smaller biotech companies.
A detailed reviewed of the steps
venture capitalists and companies are
taking — models such as fail-fast R&D, asset-centric funding and more.
Proposal of a model that
could radically change R&D by taking a
much more holistic approach to drug
development, sharing information to
learn in real time across the cycle of care
and fundamentally changing how risk
and reward are allocated.
This report has been developed by Medicus AI, a leading technology company supporting the diagnostic testing partners with an innovative digital health solution.
We embarked on this study to better assess and understand the challenges facing medical biologists and the healthcare industry, and to identify solutions to support a new era of healthcare.
The research included over 2,200 survey participants, and almost 20 expert interviews, and was completed in December 2020.
10 healthcare players aiming beyond health equality to conquer health equityInsights10
Pharma's reputation may have improved during the pandemic, but that also meant that diversity, equity, and inclusion (DEI) issues were given more attention. Pharma companies have mostly concentrated on equality in recent years, but this new era of health equity is needed to address the expanding population's DEI challenges.
To get a report in detail, contact us at - info@insights10.com
Tomorrow’s Lab Today: Focus areas for medical biology and diagnostic testing ...Serene Touma
Healthcare will require a new approach and tools to support new patient expectations in 2020. A patient-centric approach to healthcare will be more relevant than ever.
Covid-19 has uncovered new challenges and weaknesses in care that are dependent on a centralized set-up.
What is becoming more and more clear is that diagnostic labs need to evolve and up their game to stay relevant. This will continue to bring value to patients throughout the healthcare journey.
A key focus in 2021 will be taking a look at building and maintaining better relationships between private and public players in patient care.
Presentation on current state of pharmaceutical drug research and ideas for change. It addresses how the pharmaceutical industry, NIH, Government, HealthCare Law, OIG, Public Health
HealthXL is the global clearing house for innovation in healthcare. We catalyse collaboration between leading brands in healthcare and the most exciting tech companies to improve the lives of millions of people.
Our partners are Bupa, Cleveland Clinic, Becton Dickinson, IBM, ICON, ResMed, Janssen Healthcare Innovation, Linde Healthcare, Novartis, Partners HealthCare, Silicon Valley Bank and EY.
Together with our partners we establish audacious goals (Moonshots) to work towards within healthcare. Then we search for innovators in digital health that can work with us and our partners to achieve those Moonshots. We help them find each other, create business partnerships and facilitate their relationship through collaboration
Health 2.0 Is Here Now What Opma Mtg May 7 2009 Slide ShareNat Bourre
An overview of Health 2.0 in Canada, addressing the main concerns of Canadian pharmaceutical marketers. Plan-of-action for pharmaceutical marketers to take small steps in integrating social media into their business plan. At the very least, get involved in social media yourself, and closely monitor your brand`s mentions on social networks.
Dr. Jules Mitchel, President of Target Health Inc., presents "How Creative Can One Be When Working with the FDA to Optimize the Drug and Device Development Process?" at the October 29 iCAN-Global Entrepreneur's Breakfast Forum.
Chelation Partners is solving sepsis with DIBI, and iron binding polymer that augments a natural defense to infections. It slows infections and the over-reaction of the immune system known as cytokine storm, which kills patients. It is immune to antibiotic resistance and effective against a very broad spectrum of disease causing microorganisms.
Normal Labour/ Stages of Labour/ Mechanism of LabourWasim Ak
Normal labor is also termed spontaneous labor, defined as the natural physiological process through which the fetus, placenta, and membranes are expelled from the uterus through the birth canal at term (37 to 42 weeks
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
The simplified electron and muon model, Oscillating Spacetime: The Foundation...RitikBhardwaj56
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Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
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A Strategic Approach: GenAI in EducationPeter Windle
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A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
Advantages and Disadvantages of CMS from an SEO Perspective
Bill & Melinda Gates foundation - Ken Duncan
1. Partnerships in drug discovery and
development for diseases of the
developing world
Ken Duncan
BioDundee, Dundee
29 May, 2013
2. 2
TOPICS
1. Introduction to the work of the Bill &
Melinda Gates Foundation
2. Drug discovery portfolio
3. Importance of partnerships in TB drug
discovery and development
3. 3
TOPICS
1. Introduction to the work of the Bill &
Melinda Gates Foundation
2. Drug discovery portfolio
3. Importance of partnerships in TB drug
discovery and development
5. Our History
Bill and Melinda
read an article
about rotavirus
They officially
create the
foundation
Warren Buffett
decides to
give Berkshire
Hathaway stock
1998 2000 2006 2008
Bill joins Melinda
full-time at the
foundation
6. $36.4 billion
Asset trust endowment
$26 billion
Grants Since inception
1,100
Employees worldwide
$3.4 billion
2012 grants payments
$31.3 billion
Warren Buffet pledge
Headquarters: Seattle
Offices: London, Washington DC
Country Offices: China, India
Country Representatives:
Ethiopia, South Africa, Nigeria
Reach & Presence
7. What We Focus On
What are
the areas
of greatest
need?
Where can
we have
the greatest
impact?
9. 2011 Grants Paid Summary
For the year ended December 31, 2011. Amount in thousands.
(by Program Area)
Global Health $1,977,507
Global Development $667,780
United States Program $486,917
Operations/Non-Program Grants $48,466
Strategic Media Partnerships $18,379
Policy & Government Affairs $9,117
10. Integrated Approach for Global Health
VACCINES
VECTOR CONTROL
SANITATION
FAMILY HEALTH
DRUGS
DIAGNOSTICS
11. How Our Strategies Align
All strategies seek
transformational change.
All strategies rely on partners and
grantees to carry out the work.
All strategies emphasize
technology.
12. TOPICS
1. Introduction to the work of the Bill &
Melinda Gates Foundation
2. Drug discovery portfolio
3. Importance of partnerships in TB drug
discovery and development
19. Grantees and partners
Target Lead Candidate
Lead
Optimisation
Target
validation
Pre-clinical Clinical
Development
Lead
Identification
Target
identification
Product Development Partnerships
Academia, Institutes
Pharma
Biotech
20. TOPICS
1. Introduction to the work of the Bill &
Melinda Gates Foundation
2. Drug discovery portfolio
3. Importance of partnerships in TB drug
discovery and development
21. TB treatment today
6-24 months
Multiple drugs
Isoniazid
Rifampicin
Pyrazinamide
Ethambutol
Complexity: DOTS
Safety, drug-drug interactions
The World needs a
shorter, safer drug
regimen
23. Importance of Partnerships
Target Lead Candidate
Lead
Optimisation
Target
validation
Pre-clinical Clinical
Development
Lead
Identification
Target
identification
TBDA
CPTR
26. TBDA
Next generation therapy
Goal:
A new first line drug regimen
that works in one month or less
Problem:
Few new drug candidates, little
diversity
Solution:
An integrated cross-industry-
academia discovery partnership
Challenge:
27. TBDA
The TBDA is a groundbreaking partnership between seven pharmaceutical companies and
six research institutions collaborating on early TB drug discovery
The TB Drug Accelerator
How it works…
Company
Compound
Libraries
Collaborative Discovery Research 5 new preclinical
candidates
2016
1 month regimen
proof of concept
2021
• Hit and Lead Generation
• Target Identification
• Lead Optimization
Research Institutions: Pharmaceutical Companies: With support from:
28. TBDA
The TBDA is a New Paradigm For Drug Discovery
The TBDA offers a new approach that addresses many of the bottlenecks in the way TB
drugs are currently developed
ONLY THE BEST CANDIDATES ADVANCE
Early
Collaboration
Avoid
Redundancy
Data
Sharing
Maximize
Efficiency
Overcome
Competitive
Barriers
Companies Work
on Each Other’s
Compounds
29. TBDA
• Partnerships such as the TBDA show how industry and others can work
together in new ways to support global health innovation
• The TBDA model could be applied to other disease areas that lack incentives
for research or require combination drug therapies
The TBDA Offers a Model for
Other Initiatives
31. All Rights Reserved. Bill & Melinda Gates Foundation is a registered trademark in the United States and other countries.
Learn More
www.GatesFoundation.org
www.ImpatientOptimists.org
BillandMelindaGatesFoundation
@GatesFoundation
Editor's Notes
Broken up talk into three sections
Broken up talk into three sections
The Bill & Melinda Gates Foundation is a private foundation. The family decided to invest their resource to make their beliefs a reality , ALL LIVES NO MATTER WHERE THEY ARE BEING LIVED HAVE EQUAL VALUE. TRANSITION - This belief is the building blocks of our work.
More than a decade ago, Bill and Melinda read a newspaper article about the millions of children dying each year in poor countries from diseases that most people in the United States don’t have to worry about. One disease in particular—rotavirus—caught their attention. It was killing half a million children a year. They’d never even heard of rotavirus. They thought that that figure might be a typo. In 2006, Warren Buffett surprised them with a pledge of most of his shares in Berkshire Hathaway, doubling the foundation’s annual grantmaking and potential impact. In 2008,Bill made his transition from Microsoft, joining Melinda in a full-time role at the foundation. The foundation was established on Bill’s and Melinda’s passion to address some of the inequities in the world, with the premise that all lives, no matter where they are being lived, have equal value
Total 2012 Grant Payments: $3.4 billion (figure includes other direct charitable contributions of $234 million)Asset Trust Endowment: $36.4 billion (as of December, 31, 2012)Remaining Warren Buffet Pledge: $31.3 billion
To be successful, we have to focus on a set of problems. To do that, we ask two key questions.
Work divided into 3 main areasUS programs: education,libraries, and Pacific NWGlobal Development:Agricultural Development; Financial Services for the Poor; Water, Sanitation & Hygiene; Special InitiativesGlobal Health:harnesses advances in science and technology to save lives in poor countriesfocus on the health problems that have a major impact in developing countries but get too little attention and funding. Where proven tools exist, we support sustainable ways to improve their delivery. Where they don’t, we invest in research and development of new interventions, such as vaccines, drugs, and diagnostics. we allocate about half of our resources to our work in global health, a quarter to our work in the United States, and another quarter to our work in global development
To give you a sense of our scale and how we allocate these funds:Our endowment (as of Dec. 31, 2012) is $36.4 billion. We now employee over 1,100 people, and each year we give out about $3.4 billion in grants as of last year.This chart illustrates where our grants were made in 2011. You can see that Global Health received about 63 percent of our grantee funds with investments of more than $1.98 billion. Global Development grantees received $668 million while U.S. Program grantees received $487 million—about 21 percent and 16 percent of total program-related grants, respectively. While we are the largest charitable foundation in the world, we know that our money is a drop in the bucket compared to what is needed to solve these problems. For example, California’s public education annual budget is $57 billion annually. So, we see our funding as catalytic; we leverage our funds to bring even more funding and attention to issues.Recently, Bill and Melinda accelerated the timeline to sunset the foundation. Formerly 50 years, all resources will now be spent within 20 years of their deaths.
Summary of Changes with the Global ProgramsThat’s why we decided to create a new Global Programs structure to encourage a more integrated approach to our work. Program teams focused on areas ranging from agricultural development to vaccines are now working together more closely on the discovery and delivery of health and development innovations that will meet the many needs of the people we serve.Our goal is to maximize discovery and delivery in global health and development, as well as increase the relevance and impact of our in-country work. Working across Global Programs and engaging grantees and partners alike will increase our local-country insight—which ultimately helps us achieve greater results in the countries where we work and where the most intensive need exists.Integrated ApproachOur new Global Programs structure aims to meet the many needs of the people we serve:Agricultural Development - Helping poor farm families to grow and sell more food reduces hunger and poverty.Family Planning - Family planning can significantly improve the health and welfare of women and their families.Nutrition - Proper nutrition during pregnancy and in early childhood improves children's health and the quality of their lives for years to come.Malaria - Access to drugs and tools to prevent and treat malaria have saved and improved the lives of millions of families around the world.Vaccines - Vaccines work to save and improve lives and protect children for a lifetime.Sanitation - Improved sanitation increases productivity, reduces healthcare costs, and prevents illness, disability, and early death.
All of our strategies seek enduring, transformational change in people’s lives by discovering tools and approaches that can achieve results on a broad scale.All of our strategies rely on partners and grantees to carry out the work in the field.All of our strategies make use of technology to advance our work—whether it’s online learning tools that help students progress at their own pace, GPS mapping technology to help vaccination teams in the field, or new contraceptive technologies that are cheaper and easier for women to use.
Broken up talk into three sections
Broken up talk into three sections
Current TB regimens drive down bacterial levels quickly, but require months of treatment to rid the body of all TB……The only way to overcome this persistence is through ashorter, more effective regimen
Bill and Melinda Gates started the foundation because they believe every person should have the chance to live a healthy and productive life. This belief underlies all of the foundation’s work to reduce hunger, poverty, and disease around the globe.