This document discusses global challenges facing the pharmaceutical industry and strategies for gaining a competitive edge. It outlines current challenges related to high production costs, hiring talent, investments in capital and assets, and aggressive investments. Upcoming challenges include increasing costs, more competition, financial crises, poor research, and changing markets. To gain an edge, companies must develop competencies in their medical representatives including strong selling, communication, and customer skills as well as product and market knowledge. The document provides two examples of specific products and strategies used to penetrate new markets and regain customers to outperform competitors.