This study assessed the spiritual health and psycho-wellness of 230 first year MBBS students in India. The students completed the Spiritual Health Assessment Scale (SHAS) to measure spiritual health and the Modified Mini Scale (MMS) to assess psycho-wellness. The results found that 71.3% of students had poor spiritual health. 57.39% of students were in the green zone of psycho-wellness, while others were in the orange or red zones indicating potential psychiatric issues. Students with higher SHAS scores, indicating better spiritual health, had significantly higher mean scores on the MMS, showing better psycho-wellness. Thus, poorer spiritual health was strongly associated with poorer psycho-wellness among the medical students