Assessment of awareness, knowledge, readiness, prevalence and determinants of covid-19 vaccination among adults in mvomero district- Morogoro, Tanzania
Comparing the Coronavirus pandemic in New Zealand and Iraq: A Preventive Medi...Vedica Sethi
The first cases of COVID-19 pandemic were identified in people with pneumonia in Wuhan, China, in late December 2019. It is first and foremost the most publicized pandemic, which has taken the lives of many people. It has thrown everyone into doubt and has created a collective moment of contemplation about the future. The clinical enlistment organization MedWorld of New Zealand offered for resigned and low maintenance specialists to help endeavors by the health care division and Government to battle the spread of COVID-19, in New Zealand. ( ) Starting in April, more than 20,000 tests have been done in Iraq in general (counting the Kurdistan Region), with 1202 of them turning out positive. Of those tests, half of the,m were finished by the Kurdish Ministry of Health, which implies that the other tests were finished by the Iraqi Ministry of Health. ( ) While KRG populace has been tried, just 0.05% of the remainder of the nation has been tried, along these lines featuring the conceivable difference between absolute positive case numbers between locales. Iraq is considered "particularly powerless against the plague due to being desolated" – by war and United Nations sanctions, and by partisan clash in the course of recent decades.
This paper primarily focuses on analyzing the accessible information through research papers, peer- reviewed and non-peer reviewed to understand the pandemic affecting two different countries like New Zealand- a developed country and Iraq- a developing country.
COVID 19 is a contagious disease caused by a betacoronavirus, which began in Wuhan, China in late 2019. Until now, this new illness has affected more than 6 million people worldwide, and has claimed more than 300 000 human lives. Governments around the globe were faced with the coronavirus pandemic crisis and designed strategies to slow or halt viral transmission. Measures undertaken included enforcing countrywide lockdowns, banning mass gatherings, closing schools and businesses and halting international travel.
Advanced age, having comorbidities, and vitamin D deficiency are three most important reasons for increased vulnerability to COVID-19 and also worsen complications and increase the risk of death. Despite the vast amount of information available and lessons learned, many countries are still not fully utilizing these to manage secondary peaks of COVID-19 infection. Factors associated with worse COVID-19 prognosis include, older age, ethnicity, male sex, having comorbidities, obesity, diabetes, hypertension, and smoking; all these are associate with vitamin D deficiency. COVID-19 symptomatology varies from mostly asymptomatic, to, up to 2% fatality.
Comparing the Coronavirus pandemic in New Zealand and Iraq: A Preventive Medi...Vedica Sethi
The first cases of COVID-19 pandemic were identified in people with pneumonia in Wuhan, China, in late December 2019. It is first and foremost the most publicized pandemic, which has taken the lives of many people. It has thrown everyone into doubt and has created a collective moment of contemplation about the future. The clinical enlistment organization MedWorld of New Zealand offered for resigned and low maintenance specialists to help endeavors by the health care division and Government to battle the spread of COVID-19, in New Zealand. ( ) Starting in April, more than 20,000 tests have been done in Iraq in general (counting the Kurdistan Region), with 1202 of them turning out positive. Of those tests, half of the,m were finished by the Kurdish Ministry of Health, which implies that the other tests were finished by the Iraqi Ministry of Health. ( ) While KRG populace has been tried, just 0.05% of the remainder of the nation has been tried, along these lines featuring the conceivable difference between absolute positive case numbers between locales. Iraq is considered "particularly powerless against the plague due to being desolated" – by war and United Nations sanctions, and by partisan clash in the course of recent decades.
This paper primarily focuses on analyzing the accessible information through research papers, peer- reviewed and non-peer reviewed to understand the pandemic affecting two different countries like New Zealand- a developed country and Iraq- a developing country.
COVID 19 is a contagious disease caused by a betacoronavirus, which began in Wuhan, China in late 2019. Until now, this new illness has affected more than 6 million people worldwide, and has claimed more than 300 000 human lives. Governments around the globe were faced with the coronavirus pandemic crisis and designed strategies to slow or halt viral transmission. Measures undertaken included enforcing countrywide lockdowns, banning mass gatherings, closing schools and businesses and halting international travel.
Advanced age, having comorbidities, and vitamin D deficiency are three most important reasons for increased vulnerability to COVID-19 and also worsen complications and increase the risk of death. Despite the vast amount of information available and lessons learned, many countries are still not fully utilizing these to manage secondary peaks of COVID-19 infection. Factors associated with worse COVID-19 prognosis include, older age, ethnicity, male sex, having comorbidities, obesity, diabetes, hypertension, and smoking; all these are associate with vitamin D deficiency. COVID-19 symptomatology varies from mostly asymptomatic, to, up to 2% fatality.
Advanced age, having comorbidities, and vitamin D deficiency are three most important reasons for increased vulnerability to COVID-19 and also worsen complications and increase the risk of death.
Despite the vast amount of information available and lessons learned, many countries are still not fully utilizing these to manage secondary peaks of COVID-19 infection. Factors associated with worse COVID-19 prognosis include, older age, ethnicity, male sex, having comorbidities, obesity, diabetes, hypertension, and smoking; all these are associate with vitamin D deficiency. COVID-19 symptomatology varies from
mostly asymptomatic, to, up to 2% fatality. The latter is characterized by cytokine storm, an immune reaction, diffuse arterial thromboembolism, acute respiratory distress syndrome, pulmonary oedema,and death.
COVID-19 (An International Trauma): A Brief Analysis on Research Trends, Impa...AnuragSingh1049
Corona virus disease (COVID-19); have been established as an epidemic of the century. COVID-19, a pandemic is spreading its web throughout the world affecting everyone resulting into mass destruction of populations causing human suffering, creating panic, disturbing everyone economically and stressing all kind of development of entire mankind. COVID-19 is a deadly disease that is supposed to be fatal in 4% of cases. In Severe cases this disease produces enormous respiratory harm like pneumonia, gastrointestinal disorders, weakened immune systems, kidney failure or even death. The pathology of COVID-19 is just similar to SARS and Middle Eastern respiratory syndrome (MERS) corona virus infection. There are no drugs or vaccines for corona viruses yet, including COVID-19. According to WHO Corona virus disease (COVID-19) outbreak situation is persisting with 421,792 confirmed cases and 18,883 confirmed deaths till 23 March 2020. Till now, there are no specific vaccines or treatments for COVID-19. Though, there are multiple of clinical trials, evaluations that may result into potential treatments are ongoing.
The SARS-Cov2 is highly pathogenic and has spread very rapidly.
Here we have tried to present an overview of the prevailing COVID-19 situation in terms of health impact, pathophysiology, clinical manifestations, diagnosis, management, emergency responses and preparedness.
The research literature is growing rapidly and hopefully it will help in finding an effective vaccine (many in trials) and the best practice for the management and treatment of symptomatic cases.
The health, social and economic impacts would be high by this global killer.
We should be able to learn lessons and hopefully we will be more prepared for any such event in future.
COVID-19: Knowledge Base, Attitudes and Practices among Practising Journalist...Premier Publishers
The Coronavirus pandemic is presently the topic of discussion among various segments of global society. From the developed North to the developing South, within economically poor and rich countries, the huge rates of infection and resulting deaths from the pandemic has surpassed anything seen for a long time. Health systems and economies in both developed and developing countries are challenged in ways never imagined. The global efforts to mitigate the effects of the pandemic are moving at a very fast pace. Public health information is one of the strategies being used to ensure that persons are knowledgeable about the pandemic and adopt practices and protocols that will stem infections within the community. This study was undertaken to gauge the knowledge levels of journalists in the Nigerian capital city of Abuja and the impact of the knowledge on their attitudes and practices. The knowledge, attitudes and practice study model were used to gauge the interrelatedness of these variables among the study group. Logit regression tests, t-tests, chi-square and descriptive analysis were used to determine knowledge levels as well as what factors influenced attitudes and practices towards COVID-19 within the group. Overall, knowledge level amongst the study group was good and had a positive impact on attitude patterns. However, there was no high positive correlation between knowledge and practices. It is suggested that journalists in Nigeria must adhere to public health protocols in order to be able to engage in multi-platform public health information awareness publications which will sensitize the public into observing the COVID containment protocols.
The PowerPoint "COVID-19 Pandemic" by Arnav Gupta is about COVID-19. It talks about where it started, how it spreads, and what countries did to stop it. It explains how it changed life and work, the problems for doctors, and how vaccines were made and given to people. It looks at new types of the virus and health problems after COVID. It ends by saying how important it is for countries to work together and learn from this.
An overview on Monkeypox, Current Paradigms and Advances in its Vaccination, ...Dr Varruchi Sharma
Monkeypox virus is an orthopoxvirus sharing the common genus with variola and vaccinia virus. Most of the monkeypox (MPX) cases had been reported from the central and west African region (the main endemic areas) prior to 2022 but there was a sudden outbreak in May, 2022 disseminating the infections to thousands of people even in non-endemic countries, posing a global public health emergency. MPX was considered a rae and neglected disease, however the 2022 MPX outbreaks in multiple countries attracted attention of worldwide researchers to pace up for carrying out researches on various aspects of MPXV including attempts to design and develop diagnostics, vaccines, drugs and therapeutics counteract MPX. Apart from being a zoonotic disease, the current outbreaks highlighted rapid human-to-human transmission of MPXV, besides the reverse zoonosis has also been documented with recent first report of human-to-dog transmission, urging a call for the importance of one health approach. Atypical and unusual disease manifestations as well asymptomatic MPXV infections have also been observed during 2022 MPX outbreak. the affected patients typically develop a rash resulting in a mild disease followed by recovery with some supportive care and use of antivirals such as tecovirimat, cidofovir and brincidofovir in severe disease cases. Modified vaccinia Ankara (MVA) vaccine with an excellent safety profile has been recommended to patients with higher risk exposure and immunocompromised individuals. Moreover, another vaccine the replication-competent vaccine (ACAM2000) could be a suitable alternative to MVA’s non-availability to some selective immunocompetent individuals. Current review highlights the salient aspects of management and treatment of monkeypox along with underlying promises in terms of therapeutics and a variety of challenges posed due to current global public health emergency situation to counteract MPX.
COVID-19 Facts vs Opinion: Nonchalant Responses of The Indonesian PeopleJosephineSurya2
This paper is submitted to fulfill the English 2 Final Exam Project study program Industrial Engineering 2nd semester Buddhi Dharma University, Tangerang. Lecturer: Dra. Harisa Mardiana, M.Pd.
Modified SEIR and machine learning prediction of the trend of the epidemic o...IJECEIAES
Susceptible exposed infectious recovered (SEIR) is a fitting model for coronavirus disease (COVID-19) spread prediction. Hence, to examine the effect of different levels of social distancing on the spreading of the disease, a variable was introduced in the SEIR equations system used in this work. We also used an artificial intelligence approach using a machine learning (ML) method known as deep neural network. This modified SEIR model was applied on the available initial spread data until June 25th, 2021 for the Hashemite Kingdom of Jordan. Without lockdown in Jordan, the analysis demonstrates potential infection to roughly 3.1 million people during the peak of spread approximately 3 months, starting from the date of lockdown (March 21st). Conversely, the present partial lockdowns strategy by the Kingdom was expected to reduce the predicted number of infections to 0.5 million in 9 months period. The analysis also demonstrates the ability of stricter lockdowns to effectively flatten the graph curve of COVID-19 in Jordan. Our modified SEIR and deep neural network (DNN) model were efficient in the prediction of COVID-19 epidemic sizes and peaks. The measures taken to control the epidemic by the government decreased the size of the COVID-19 epidemic.
Covid-19: risk assessment and mitigation measures in healthcare and non healt...Ahmed Hasham
The coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), is the third emerging human coronavirus, leading to fatal respiratory
distress and pneumonia. The disease originated in December 2019 in Wuhan City,
Hubei province, China. As of 23 November 2021, over 258 million cases and 5.1 million deaths
have been reported in more than 222 countries and territories worldwide. The COVID-19 is
under biological hazards group 4 of high risk of spreading to the community with the potential
to overwhelm the health system, especially in resource limited countries. Transmission
of COVID-19 within healthcare and non-healthcare facilities has been recorded. Therefore,
several authorities such as the World Health Organization (WHO), the Centers for Disease
Control and Prevention (CDC), and other global partners issued guidance to mitigate the
COVID-19 pandemic in these facilities. A global emergency due to the COVID-19 pandemic
requires various studies of mitigation measures and risk assessment. The Failure Mode and
Effects Analysis (FMEA) was used as a tool for risk assessment in healthcare and clinical
fields that assigns a numerical value to each risk associated with failure. Therefore, in this
review, the FMEA procedure was used to evaluate the COVID-19 risks and risk groups in
health care and non-healthcare workplaces. Proposed mitigation measures and risk ranking
tools were also summarized. The COVID-19 transmission risk should be theoretically and
practically reduced by applying the best hygienic practices. However, providing safe work
practices must be improved for infection control measures in healthcare and non-healthcare
workplaces. Additionally, it is recommended to reassess the risk of COVID-19 infection from
time to time, especially after vaccines availability.
Emergency management 11
Emergency Management
Abstract:
In the month of December, 2019 there was outbreak of pneumonia with unknown reason in Wuhan, China. Wuhan is the center of attention because of the respiratory disorder cause by a virus called Corona and also known as Novel COVID – 19. Validate the existence of this virus was also diagnosed in Wuhan. Then it start spreading all over the world due to the social gatherings. It ultimately take thousands of people towards death. Then after its huge destruction a final step of lockdown is taken up by the government of each country. The animal-to-human transmission was presumed as the main mechanism. It was concluded that the virus could also be transmitted from human-to-human, and symptomatic people are the most frequent source of COVID-19 spread. The virus-host interaction and the evolution of the epidemic, with specific reference to the times when the epidemic will reach its peak.
Introduction:
There is scanty knowledge on the actual pandemic potential of this new SARS-like virus. It might be speculated that SARS-CoV-2 epidemic is grossly underdiagnosed and that the infection is silently spreading across the globe. There are no comparable analogies to corona virus. This virus is not like any of the other epidemiological threats that have emerged in recent decades; it is less fatal but much more contagious.
Distribution of cases by the following:
· Time: The outbreak of 2019 novel coronavirus disease (COVID-19) was first reported on December 31, 2019.
· Place: the epidemiology of 2019 novel coronavirus disease (COVID-19) in a remote region of China, far from Wuhan, we analyzed the epidemiology of COVID-19 in Gansu Province
Explanation of the research topic (corona virus):
As the outbreak of coronavirus disease 2019 (COVID-19) is rapidly expanding in China and beyond, with the potential to become a world-wide pandemic, real-time analyses of epidemiological data are needed to increase situational awareness and inform interventions. The current most likely hypothesis is that an intermediary host animal has played a role in the transmission. Identifying the animal source of the 2019-nCoV would help to ensure that there will be no further future similar outbreaks with the same virus and will also help understanding the initial spread of the disease.
Numerator (cases of corona virus):
Deaths divided the total of deaths plus recoveries. In early days because of the exponential increase new cases significantly outpace recoveries. You’re dividing by new cases but the numerator hasn’t had a chance to catch up to the death toll yet to be associated with those cases. If you look at COVID 19 on Feb 17, you get the 2% number only if dividing by total cases. If you look vs recovered cases, it’s 13%.
The WHO’s fatality percentage, announced March 17, 2020, is based simply on the number of deaths g.
Dermatological health in the COVID-19 erakomalicarol
COVID-19 and its impact on dermatological health was reviewed
from theoretical and statistical frameworks in the present study. A
cross-sectional and retrospective work was documented with a selection of sources indexed to Scopus, considering the period from
2019 to 2022, as well as the search by keywords. Approaches were
discussed in order to outline a comprehensive model that considered the differences between the parties involved, as well as their
relationships in a risk context. The proposal contributes to the state
of the question in terms of the prediction of contingencies derived
from the probability and affectation of dermatological health
The Coronavirus Disease – 2019 (COVID-19) is officially now a pandemic and not just a public health emergency of international concern as previously labelled. Worldwide, the new coronavirus has infected more than 4.9 million people and leaving more than 300,000 people dead in 188 countries. As countries of the world get locked down in an effort to contain the widespread of the virus, experts are concern about the global impacts of the pandemic on individuals, countries and the world at large. Millions of people are currently under quarantine across the globe. Many countries have responded by proclaiming a public health emergency, closed their borders and restrict incoming flights from high risk countries. This has grossly affected the travel plan of many. Several international programs, conferences, workshops and sporting activities are either postponed or cancelled. As the number of confirmed cases continues to escalate across the globe, hospitals seems to be running out of medical supplies, hospital spaces and personnel. Health workers are being overwhelmed by the numbers of people requesting for testing and treatment. Many of such health workers have been infected with the coronavirus and even lost their lives since the fight against COVID-19 started. Public health experts are also concerned about the huge medical wastes coming from the hospitals at this time and the adverse effects associated with improper management of such medical wastes, both at the hospital and community levels. The pandemic has also impacted negatively on the global economy. There have been serious crises in the stock market, with gross fall in the price of crude oil resulting in inflation and economic hardship among the populace. Many are currently out of job and as a result, the level of crime, protest and violence have continued to escalate in different parts of the world. The deaths of loved ones due to the coronavirus has left many emotionally traumatized. Nigeria, like other African countries is not spared of the ravaging effects of the pandemic, even as the government take strict measures to contain the virus. No doubt, this is very challenging, but the country is capable of surmounting the virus with the needed help from her international partners and cooperation from the citizenry. But if we as a people, remain complacent and continue with business as usual, without taking measures to flatten the curve, the disease will escalate too quickly beyond our capacity to handle and our health system will be overwhelmed and may collapse eventually. We cannot therefore afford to be complacent in our response to containing the pandemic.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Advanced age, having comorbidities, and vitamin D deficiency are three most important reasons for increased vulnerability to COVID-19 and also worsen complications and increase the risk of death.
Despite the vast amount of information available and lessons learned, many countries are still not fully utilizing these to manage secondary peaks of COVID-19 infection. Factors associated with worse COVID-19 prognosis include, older age, ethnicity, male sex, having comorbidities, obesity, diabetes, hypertension, and smoking; all these are associate with vitamin D deficiency. COVID-19 symptomatology varies from
mostly asymptomatic, to, up to 2% fatality. The latter is characterized by cytokine storm, an immune reaction, diffuse arterial thromboembolism, acute respiratory distress syndrome, pulmonary oedema,and death.
COVID-19 (An International Trauma): A Brief Analysis on Research Trends, Impa...AnuragSingh1049
Corona virus disease (COVID-19); have been established as an epidemic of the century. COVID-19, a pandemic is spreading its web throughout the world affecting everyone resulting into mass destruction of populations causing human suffering, creating panic, disturbing everyone economically and stressing all kind of development of entire mankind. COVID-19 is a deadly disease that is supposed to be fatal in 4% of cases. In Severe cases this disease produces enormous respiratory harm like pneumonia, gastrointestinal disorders, weakened immune systems, kidney failure or even death. The pathology of COVID-19 is just similar to SARS and Middle Eastern respiratory syndrome (MERS) corona virus infection. There are no drugs or vaccines for corona viruses yet, including COVID-19. According to WHO Corona virus disease (COVID-19) outbreak situation is persisting with 421,792 confirmed cases and 18,883 confirmed deaths till 23 March 2020. Till now, there are no specific vaccines or treatments for COVID-19. Though, there are multiple of clinical trials, evaluations that may result into potential treatments are ongoing.
The SARS-Cov2 is highly pathogenic and has spread very rapidly.
Here we have tried to present an overview of the prevailing COVID-19 situation in terms of health impact, pathophysiology, clinical manifestations, diagnosis, management, emergency responses and preparedness.
The research literature is growing rapidly and hopefully it will help in finding an effective vaccine (many in trials) and the best practice for the management and treatment of symptomatic cases.
The health, social and economic impacts would be high by this global killer.
We should be able to learn lessons and hopefully we will be more prepared for any such event in future.
COVID-19: Knowledge Base, Attitudes and Practices among Practising Journalist...Premier Publishers
The Coronavirus pandemic is presently the topic of discussion among various segments of global society. From the developed North to the developing South, within economically poor and rich countries, the huge rates of infection and resulting deaths from the pandemic has surpassed anything seen for a long time. Health systems and economies in both developed and developing countries are challenged in ways never imagined. The global efforts to mitigate the effects of the pandemic are moving at a very fast pace. Public health information is one of the strategies being used to ensure that persons are knowledgeable about the pandemic and adopt practices and protocols that will stem infections within the community. This study was undertaken to gauge the knowledge levels of journalists in the Nigerian capital city of Abuja and the impact of the knowledge on their attitudes and practices. The knowledge, attitudes and practice study model were used to gauge the interrelatedness of these variables among the study group. Logit regression tests, t-tests, chi-square and descriptive analysis were used to determine knowledge levels as well as what factors influenced attitudes and practices towards COVID-19 within the group. Overall, knowledge level amongst the study group was good and had a positive impact on attitude patterns. However, there was no high positive correlation between knowledge and practices. It is suggested that journalists in Nigeria must adhere to public health protocols in order to be able to engage in multi-platform public health information awareness publications which will sensitize the public into observing the COVID containment protocols.
The PowerPoint "COVID-19 Pandemic" by Arnav Gupta is about COVID-19. It talks about where it started, how it spreads, and what countries did to stop it. It explains how it changed life and work, the problems for doctors, and how vaccines were made and given to people. It looks at new types of the virus and health problems after COVID. It ends by saying how important it is for countries to work together and learn from this.
An overview on Monkeypox, Current Paradigms and Advances in its Vaccination, ...Dr Varruchi Sharma
Monkeypox virus is an orthopoxvirus sharing the common genus with variola and vaccinia virus. Most of the monkeypox (MPX) cases had been reported from the central and west African region (the main endemic areas) prior to 2022 but there was a sudden outbreak in May, 2022 disseminating the infections to thousands of people even in non-endemic countries, posing a global public health emergency. MPX was considered a rae and neglected disease, however the 2022 MPX outbreaks in multiple countries attracted attention of worldwide researchers to pace up for carrying out researches on various aspects of MPXV including attempts to design and develop diagnostics, vaccines, drugs and therapeutics counteract MPX. Apart from being a zoonotic disease, the current outbreaks highlighted rapid human-to-human transmission of MPXV, besides the reverse zoonosis has also been documented with recent first report of human-to-dog transmission, urging a call for the importance of one health approach. Atypical and unusual disease manifestations as well asymptomatic MPXV infections have also been observed during 2022 MPX outbreak. the affected patients typically develop a rash resulting in a mild disease followed by recovery with some supportive care and use of antivirals such as tecovirimat, cidofovir and brincidofovir in severe disease cases. Modified vaccinia Ankara (MVA) vaccine with an excellent safety profile has been recommended to patients with higher risk exposure and immunocompromised individuals. Moreover, another vaccine the replication-competent vaccine (ACAM2000) could be a suitable alternative to MVA’s non-availability to some selective immunocompetent individuals. Current review highlights the salient aspects of management and treatment of monkeypox along with underlying promises in terms of therapeutics and a variety of challenges posed due to current global public health emergency situation to counteract MPX.
COVID-19 Facts vs Opinion: Nonchalant Responses of The Indonesian PeopleJosephineSurya2
This paper is submitted to fulfill the English 2 Final Exam Project study program Industrial Engineering 2nd semester Buddhi Dharma University, Tangerang. Lecturer: Dra. Harisa Mardiana, M.Pd.
Modified SEIR and machine learning prediction of the trend of the epidemic o...IJECEIAES
Susceptible exposed infectious recovered (SEIR) is a fitting model for coronavirus disease (COVID-19) spread prediction. Hence, to examine the effect of different levels of social distancing on the spreading of the disease, a variable was introduced in the SEIR equations system used in this work. We also used an artificial intelligence approach using a machine learning (ML) method known as deep neural network. This modified SEIR model was applied on the available initial spread data until June 25th, 2021 for the Hashemite Kingdom of Jordan. Without lockdown in Jordan, the analysis demonstrates potential infection to roughly 3.1 million people during the peak of spread approximately 3 months, starting from the date of lockdown (March 21st). Conversely, the present partial lockdowns strategy by the Kingdom was expected to reduce the predicted number of infections to 0.5 million in 9 months period. The analysis also demonstrates the ability of stricter lockdowns to effectively flatten the graph curve of COVID-19 in Jordan. Our modified SEIR and deep neural network (DNN) model were efficient in the prediction of COVID-19 epidemic sizes and peaks. The measures taken to control the epidemic by the government decreased the size of the COVID-19 epidemic.
Covid-19: risk assessment and mitigation measures in healthcare and non healt...Ahmed Hasham
The coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), is the third emerging human coronavirus, leading to fatal respiratory
distress and pneumonia. The disease originated in December 2019 in Wuhan City,
Hubei province, China. As of 23 November 2021, over 258 million cases and 5.1 million deaths
have been reported in more than 222 countries and territories worldwide. The COVID-19 is
under biological hazards group 4 of high risk of spreading to the community with the potential
to overwhelm the health system, especially in resource limited countries. Transmission
of COVID-19 within healthcare and non-healthcare facilities has been recorded. Therefore,
several authorities such as the World Health Organization (WHO), the Centers for Disease
Control and Prevention (CDC), and other global partners issued guidance to mitigate the
COVID-19 pandemic in these facilities. A global emergency due to the COVID-19 pandemic
requires various studies of mitigation measures and risk assessment. The Failure Mode and
Effects Analysis (FMEA) was used as a tool for risk assessment in healthcare and clinical
fields that assigns a numerical value to each risk associated with failure. Therefore, in this
review, the FMEA procedure was used to evaluate the COVID-19 risks and risk groups in
health care and non-healthcare workplaces. Proposed mitigation measures and risk ranking
tools were also summarized. The COVID-19 transmission risk should be theoretically and
practically reduced by applying the best hygienic practices. However, providing safe work
practices must be improved for infection control measures in healthcare and non-healthcare
workplaces. Additionally, it is recommended to reassess the risk of COVID-19 infection from
time to time, especially after vaccines availability.
Emergency management 11
Emergency Management
Abstract:
In the month of December, 2019 there was outbreak of pneumonia with unknown reason in Wuhan, China. Wuhan is the center of attention because of the respiratory disorder cause by a virus called Corona and also known as Novel COVID – 19. Validate the existence of this virus was also diagnosed in Wuhan. Then it start spreading all over the world due to the social gatherings. It ultimately take thousands of people towards death. Then after its huge destruction a final step of lockdown is taken up by the government of each country. The animal-to-human transmission was presumed as the main mechanism. It was concluded that the virus could also be transmitted from human-to-human, and symptomatic people are the most frequent source of COVID-19 spread. The virus-host interaction and the evolution of the epidemic, with specific reference to the times when the epidemic will reach its peak.
Introduction:
There is scanty knowledge on the actual pandemic potential of this new SARS-like virus. It might be speculated that SARS-CoV-2 epidemic is grossly underdiagnosed and that the infection is silently spreading across the globe. There are no comparable analogies to corona virus. This virus is not like any of the other epidemiological threats that have emerged in recent decades; it is less fatal but much more contagious.
Distribution of cases by the following:
· Time: The outbreak of 2019 novel coronavirus disease (COVID-19) was first reported on December 31, 2019.
· Place: the epidemiology of 2019 novel coronavirus disease (COVID-19) in a remote region of China, far from Wuhan, we analyzed the epidemiology of COVID-19 in Gansu Province
Explanation of the research topic (corona virus):
As the outbreak of coronavirus disease 2019 (COVID-19) is rapidly expanding in China and beyond, with the potential to become a world-wide pandemic, real-time analyses of epidemiological data are needed to increase situational awareness and inform interventions. The current most likely hypothesis is that an intermediary host animal has played a role in the transmission. Identifying the animal source of the 2019-nCoV would help to ensure that there will be no further future similar outbreaks with the same virus and will also help understanding the initial spread of the disease.
Numerator (cases of corona virus):
Deaths divided the total of deaths plus recoveries. In early days because of the exponential increase new cases significantly outpace recoveries. You’re dividing by new cases but the numerator hasn’t had a chance to catch up to the death toll yet to be associated with those cases. If you look at COVID 19 on Feb 17, you get the 2% number only if dividing by total cases. If you look vs recovered cases, it’s 13%.
The WHO’s fatality percentage, announced March 17, 2020, is based simply on the number of deaths g.
Dermatological health in the COVID-19 erakomalicarol
COVID-19 and its impact on dermatological health was reviewed
from theoretical and statistical frameworks in the present study. A
cross-sectional and retrospective work was documented with a selection of sources indexed to Scopus, considering the period from
2019 to 2022, as well as the search by keywords. Approaches were
discussed in order to outline a comprehensive model that considered the differences between the parties involved, as well as their
relationships in a risk context. The proposal contributes to the state
of the question in terms of the prediction of contingencies derived
from the probability and affectation of dermatological health
The Coronavirus Disease – 2019 (COVID-19) is officially now a pandemic and not just a public health emergency of international concern as previously labelled. Worldwide, the new coronavirus has infected more than 4.9 million people and leaving more than 300,000 people dead in 188 countries. As countries of the world get locked down in an effort to contain the widespread of the virus, experts are concern about the global impacts of the pandemic on individuals, countries and the world at large. Millions of people are currently under quarantine across the globe. Many countries have responded by proclaiming a public health emergency, closed their borders and restrict incoming flights from high risk countries. This has grossly affected the travel plan of many. Several international programs, conferences, workshops and sporting activities are either postponed or cancelled. As the number of confirmed cases continues to escalate across the globe, hospitals seems to be running out of medical supplies, hospital spaces and personnel. Health workers are being overwhelmed by the numbers of people requesting for testing and treatment. Many of such health workers have been infected with the coronavirus and even lost their lives since the fight against COVID-19 started. Public health experts are also concerned about the huge medical wastes coming from the hospitals at this time and the adverse effects associated with improper management of such medical wastes, both at the hospital and community levels. The pandemic has also impacted negatively on the global economy. There have been serious crises in the stock market, with gross fall in the price of crude oil resulting in inflation and economic hardship among the populace. Many are currently out of job and as a result, the level of crime, protest and violence have continued to escalate in different parts of the world. The deaths of loved ones due to the coronavirus has left many emotionally traumatized. Nigeria, like other African countries is not spared of the ravaging effects of the pandemic, even as the government take strict measures to contain the virus. No doubt, this is very challenging, but the country is capable of surmounting the virus with the needed help from her international partners and cooperation from the citizenry. But if we as a people, remain complacent and continue with business as usual, without taking measures to flatten the curve, the disease will escalate too quickly beyond our capacity to handle and our health system will be overwhelmed and may collapse eventually. We cannot therefore afford to be complacent in our response to containing the pandemic.
Similar to Assessment of awareness, knowledge, readiness, prevalence and determinants of covid-19 vaccination.pptx (20)
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
2. RESEARCH TITLE:
ASSESSMENT OF AWARENESS, KNOWLEDGE,
READINESS, PREVELENCE AND DETERMINANTS
OF COVID-19 VACCINATION AMONG ADULTS IN
MVOMERO DISTRICT, MOROGORO.
4. BACKGROUND
COVID-19 is caused by the new SARS-cov-2. Coronaviruses are large,
enveloped, single-stranded RNA viruses found in humans and other
mammals. Coronaviruses cause respiratory, gastrointestinal, and
neurological disease. SARS-cov-2 is the third corona virus that has caused
severe disease in humans to spread globally in the past 2 decades. The
first coronavirus that caused SARS, which was thought to originate in
Foshan, China, and resulted in the 2002-2003. The second was the
coronavirus-caused MERS, which originated from the Arabian peninsula in
2012. Through genetic recombination and variation, coronaviruses can
adapt to and infect new hosts. Bats are the natural reservoir for SARS-cov-
2, but it has been suggested that humans became infected via an
intermediate host, such as the pangolin(1,2).
Droplets expelled during face-to-face exposure during talking, coughing, or
sneezing is the most common mode of transmission. Contact surface
spread (touching a surface with virus on it) is another possible mode of
transmission.
5. Background cont…
The disease may be asymptomatic or cause a wide spectrum of
symptoms including fever, dry cough, shortness of breath, fatigue,
nausea/vomiting or diarrhea, and myalgia. Anosmia or ageusia may
also be the sole presenting symptom.
Diagnosis of COVID-19 is typically made using polymerase chain
reaction testing via nasal swab. However, because of false negative
test result rates of SARS-cov-2 PCR testing of nasal swabs, clinical,
laboratory, and imaging findings may also be used to make a
presumptive diagnosis(1).
6. Background cont…
COVID-19 first emerged in December 2019, when a cluster of
patients with pneumonia of unknown cause was recognized in
Wuhan, China. As of 10th June 2022 there were a total of
512,201,219 confirmed cases of COVID-19 (i.e 6.6% of the world’s
total population), including 6,305,358 deaths were repoted
globally. In Africa as of June 2022 there were 9,039,645 confirmed
cases of COVID-19 with a total of 172,980 deaths were reported.
Among East African countries, Kenya had the leading number of
reported cases of COVID-19 of a total of 325,070 cases, followed
by Uganda 164,069 cases, then Rwanda 130,061 cases, Sudan
62,374 cases, and Burundi 42,034 cases. In united Republic of
Tanzania, from January 3rd 2020 to June 2022 there have been a
total of 35,354 confirmed cases of COVID-19 with 840 total deaths
were reported(3).
7. Background cont…
The SARS-cov-2 pandemic has inflicted almost unimaginable harm
on our lives. So far the pandemic has caused a sudden significant
increase in hospitalizations for pneumonia with multi-organ disease
including impaired function of the heart(eg myocarditis,
cardiomyopathy, ventricular arrhythmias), brain (acute
cerebrovascular disease and encephalitis), lung, liver, kidney, and
coagulation system (Venous and arterial thromboembolic events)
were observed with severe illness. Also number of lives were lost
because of the pandemic(1).
Up until the present day there is no definitive treatment for COVID-19
but there are preventive measures that are undertaken to reduce
incidences which involves personal actions (eg, physical distancing,
personal hygiene, and use of protective equipment), case and
contact identification (eg, test trace-track-isolate, proactive school or
workplace closure), regulatory actions (eg, governmental limits on
sizes of gatherings or business capacity, stay-at-home orders, and
public transport closure or restriction.
8. Background cont…
Vaccines are the most important public health measure and
most effective strategy they have been provided in different
coners of the world so as to protect the population from COVID-
19, New and more effective vaccines against the spread
disease are likely to be developed as we move through the
pandemic. More than 330 candidate vaccines are currently
under clinical evaluation globally(4). As of May 23, 2022, The
New York Times Coronavirus Vaccine Tracker lists 2 mRNA
vaccines which are Pfizer(91% efficient) and moderna(96%
efficient) have gained full approval by the US Food and Drug
Administration (FDA). One other, a viral vector vaccine
Janssen(84% efficient), has an emergency use approval (EUA)
in the United States. An EUA was requested January 31, 2022
for a protein subunit vaccine by Novavax. Globally, 12 vaccines
are approved for full use, 19 vaccines are authorized for early
or limited use, and 38 vaccines are in phase 3 clinical trials(5).
9. Background cont…
Africa’s COVID-19 vaccine uptake rose by 15% between
January(54 million doses) and February(62 million doses) as
several countries embarked on mass vaccination drives to
expand coverage and protect populations against the adverse
health impacts of the virus. The uptick was driven mainly by
vaccination campaigns in populous countries including
Democratic Republic of the Congo, Ethiopia, Kenya, and
Nigeria. To boost the COVID-19 vaccine uptake in
Africa,WHO, UNICEF, Gavi, the Vaccine Alliance, and
partners are supporting mass vaccination.
To date, the African continent has fully vaccinated just 15% of
the adult population. Of the 714 million doses received so far,
435 million or 61% has been administered resulting to decline
in COVID-19 cases. The continent reported a 10% decline in
cases in the week ending on 13 March compared with the
week before. Deaths declined by 37% over the same
period(3,6).
As of 08th April, 2022 a total of 3,435,513 people aged above
18 have been vaccined in Tanzania among 30,740,928 people
eligible to vaccinate which is equivalent to 11.1%(7).
10. Background cont…
Despite the distribution and availability of vaccines world
wide, the COVID-19 cases are still existing and thus
making it of public health importance. Although the
continent is reporting fewer and fewer cases, this does
not signal the end of the pandemic. We must maximize
on this opportunity to protect as many people as
possible with the vaccine. Vaccine hesitancy, delay, or
refusal to receive a vaccine has been a significant threat
to the effectiveness of vaccination programs and mostly
due to lack of knowledge about COVID-19 vaccination
and aweareness towards their safety also there is no
previous study investigating knowledge, attitudes, and
perceptions regarding COVID-19 vaccination among the
general population in Tanzania.
Therefore, this study will aim at assessing awareness,
knowledge, readiness, prevelence and determinants of
covid-19 vaccination among adults in mvomero district,
Morogoro.
11. References
1. Review C. Pathophysiology, Transmission, Diagnosis,
and Treatment of Coronavirus Disease 2019 (COVID-
19) A Review. 2020;2019.
2. UNITED REPUBLIC OF TANZANIA. 2021;(July).
3. who. https://covid19.who.int/region/afro/country/tz.
Available from:
https://covid19.who.int/region/afro/country/tz
4. Sonmezer MC, Sahin TK, Erul E, Ceylan FS.
Knowledge , Attitudes , and Perception towards COVID-
19 Vaccination among the Adult Population : A Cross-
Sectional Study in Turkey. 2022;2019(January):1–12.
5. MEDSCAPE. https://emedicine.medscape.com.
6. WHO Africa. https://www.afro.who.int/news/africas-
covid-19-vaccine-uptake-increases-15.
7. Ya T, Ya H. Mwenendo wa watu waliothibitika kuwa
na UVIKO-19 kwa wiki ya tarehe 03 Desemba , 2021
hadi tarehe 08 Aprili , 2022. 2022;