2014 Conference on Monitoring and Surveillance of #Asbestos-Related Diseases.
This presentation points out the transposition of European requirements in the French regulation and the two systems will be put in parallel throughout. The goal is also to describe the consequences of the French regulatory evolutions and their applications in workplace area.
Use of a passive badge for sampling asbestos among building finishing workersINRSfrance
2014 Conference on Monitoring and Surveillance of Asbestos-Related Diseases.
With millions of square meters of materials containing asbestos still in place in buildings and industrial equipment, the risk of asbestos exposure remains and will persist for several decades. Approximately nine hundred thousand workers are potentially exposed to asbestos in the French construction sector. According to the conclusions of The French National Mesothelioma Surveillance Program (PNSM) published in two thousand and eleven: Occupations most at risk are: Plumbers, pipefitters, sheet metal workers boilermakers, electricians, welders and flame cutters installationIn two thousand and ten: almost one hundred and sixty thousand workers of the general scheme of Social Security occupying “plumbing-heating activities”: eighty-five % of occupational diseases related to asbestos. But paradoxically: Few exposure data are available for these workers. This can be explained by: Size and dispersion of the majority of concerned enterprises, occasional and short-term exposure, duration of difficult samples, logistical constraints linked to conventional sampling method. To overcome these difficulties the lack of exposure data, INRS decided to investigate an alternative to conventional sampling.
With the brand Albet LabScience, we are providing you with a wide range of products for challenging filtrations in chemical and
biological laboratories, as well as for life science and analytical applications. Our extensive portfolio of filter papers is known in
laboratories throughout the world for its purity and consistency.
As a globally operating company, Hahnemühle is focusing, in addition to the standard product range for laboratories, on the
production of filter papers that are tailored to the customers’ requirements, as part of its core business
Use of a passive badge for sampling asbestos among building finishing workersINRSfrance
2014 Conference on Monitoring and Surveillance of Asbestos-Related Diseases.
With millions of square meters of materials containing asbestos still in place in buildings and industrial equipment, the risk of asbestos exposure remains and will persist for several decades. Approximately nine hundred thousand workers are potentially exposed to asbestos in the French construction sector. According to the conclusions of The French National Mesothelioma Surveillance Program (PNSM) published in two thousand and eleven: Occupations most at risk are: Plumbers, pipefitters, sheet metal workers boilermakers, electricians, welders and flame cutters installationIn two thousand and ten: almost one hundred and sixty thousand workers of the general scheme of Social Security occupying “plumbing-heating activities”: eighty-five % of occupational diseases related to asbestos. But paradoxically: Few exposure data are available for these workers. This can be explained by: Size and dispersion of the majority of concerned enterprises, occasional and short-term exposure, duration of difficult samples, logistical constraints linked to conventional sampling method. To overcome these difficulties the lack of exposure data, INRS decided to investigate an alternative to conventional sampling.
With the brand Albet LabScience, we are providing you with a wide range of products for challenging filtrations in chemical and
biological laboratories, as well as for life science and analytical applications. Our extensive portfolio of filter papers is known in
laboratories throughout the world for its purity and consistency.
As a globally operating company, Hahnemühle is focusing, in addition to the standard product range for laboratories, on the
production of filter papers that are tailored to the customers’ requirements, as part of its core business
Katalog aeroqual uv 1 ozone photometer, jual ozone photometer aeroqual, beli, info, harga, spesifikasi dan review
untuk informasi lebih lanjut kunjungi
www.tridinamika.com
untuk pemesanan dan pertanyaan hubungi via email
sales@tridinamika.com
Measurement of Formaldehyde Pollution in Ambient AirGasera Ltd.
Formaldehyde is classified as a carcinogenic compound and until today it has been difficult to monitor with existing technologies.
The GASERA ONE FORMALDEHYDE analyzer can achieve below 1 ppb detection limit, which is well below the 16 ppb recommendation for occupational exposure limit by The National Institute for Occupational Safety and Health (NIOSH) in the USA.
* Materials updated 22 June 2017
Measurement of VOCs for Air Quality Using Widely Tunable Mid-Infrared Laser S...Gasera Ltd.
Indoor Air Quality
Indoor air quality has a large impact on health, quality of life and work efficiency. Numerous indoor air impurities are responsible for respiratory diseases , allergies, intoxication and certain types of cancer. Contaminants are caused by e.g. moulds, decomposing floor covering, tobacco smoke, outgassing from furniture.
Photoacoustic detection combined with widely tunable mid-IR laser sources provides a versatile platform for various air quality applications. High-power EC-QCL in the fingerprint regions enables measurement of many VOCs and also other gases that typically are active in the common fingerprint region. Easy to operate, miniaturization possibilities and infrequent maintenance requirement provides additional benefit.
This presentation outlines the approach taken by EnviroMist, in partnership with the University of Wollongong, to develop effective dust suppression systems for the mining industry.
A thorough approach using real-time dust monitoring, airspeed monitoring and material testing will be presented as the first step to define a dust problem. Following that, the use of modeling techniques such as CFD and DEM in combination with laboratory test data allows for the variables defining a problem to be investigated.
Finally, a solution can be proposed that is specific to the conditions of the application, based on the data collected and the results predicted from the simulation modelling. The presentation includes various case studies which demonstrate the effectiveness of this approach.
W3/330 system is based on the electrolytic sensor method to measure water vapor transmission rate of film and package specimens. It has three independent testing cells and can be easily connected with 9 satellite systems.
Clean Rooms require very high quality air as even minor impurities can affect the manufacturing processes. This presentation explains the concept of a Clean Room and the role Air Purifiers play in such environments. This presentation helps explain how air purification for Clean Rooms is done and how it can be a facilitator for obtaining ISO 14644 standards.
PSC-Best Practices for Using Near Infrared Instrumentation for the Frac Sand ...Bob Schumann
An overview of using near infrared (NIR) instrumentation to measure moisture in frac sand. Presented by Marty Peters at 2020 North America Frac Sand Conference
Panorama des perturbateurs endocriniens dans l'industrie (2005 - 2015)INRSfrance
Inventaire des principaux usages et les secteurs dans lesquels sont utilisés des substances ayant des effets perturbateurs endocriniens avérés ou suspectés.
Présentation réalisée par Nicolas Bertrand, expert d'assistance à l'INRS, et présentée lors du colloque international "Substances à risques spécifiques : quels risques professionnels ? Quelle prévention ? Perturbateurs endocriniens et substances sensibilisantes." (Paris, 01-03 juin 2016)
Katalog aeroqual uv 1 ozone photometer, jual ozone photometer aeroqual, beli, info, harga, spesifikasi dan review
untuk informasi lebih lanjut kunjungi
www.tridinamika.com
untuk pemesanan dan pertanyaan hubungi via email
sales@tridinamika.com
Measurement of Formaldehyde Pollution in Ambient AirGasera Ltd.
Formaldehyde is classified as a carcinogenic compound and until today it has been difficult to monitor with existing technologies.
The GASERA ONE FORMALDEHYDE analyzer can achieve below 1 ppb detection limit, which is well below the 16 ppb recommendation for occupational exposure limit by The National Institute for Occupational Safety and Health (NIOSH) in the USA.
* Materials updated 22 June 2017
Measurement of VOCs for Air Quality Using Widely Tunable Mid-Infrared Laser S...Gasera Ltd.
Indoor Air Quality
Indoor air quality has a large impact on health, quality of life and work efficiency. Numerous indoor air impurities are responsible for respiratory diseases , allergies, intoxication and certain types of cancer. Contaminants are caused by e.g. moulds, decomposing floor covering, tobacco smoke, outgassing from furniture.
Photoacoustic detection combined with widely tunable mid-IR laser sources provides a versatile platform for various air quality applications. High-power EC-QCL in the fingerprint regions enables measurement of many VOCs and also other gases that typically are active in the common fingerprint region. Easy to operate, miniaturization possibilities and infrequent maintenance requirement provides additional benefit.
This presentation outlines the approach taken by EnviroMist, in partnership with the University of Wollongong, to develop effective dust suppression systems for the mining industry.
A thorough approach using real-time dust monitoring, airspeed monitoring and material testing will be presented as the first step to define a dust problem. Following that, the use of modeling techniques such as CFD and DEM in combination with laboratory test data allows for the variables defining a problem to be investigated.
Finally, a solution can be proposed that is specific to the conditions of the application, based on the data collected and the results predicted from the simulation modelling. The presentation includes various case studies which demonstrate the effectiveness of this approach.
W3/330 system is based on the electrolytic sensor method to measure water vapor transmission rate of film and package specimens. It has three independent testing cells and can be easily connected with 9 satellite systems.
Clean Rooms require very high quality air as even minor impurities can affect the manufacturing processes. This presentation explains the concept of a Clean Room and the role Air Purifiers play in such environments. This presentation helps explain how air purification for Clean Rooms is done and how it can be a facilitator for obtaining ISO 14644 standards.
PSC-Best Practices for Using Near Infrared Instrumentation for the Frac Sand ...Bob Schumann
An overview of using near infrared (NIR) instrumentation to measure moisture in frac sand. Presented by Marty Peters at 2020 North America Frac Sand Conference
Panorama des perturbateurs endocriniens dans l'industrie (2005 - 2015)INRSfrance
Inventaire des principaux usages et les secteurs dans lesquels sont utilisés des substances ayant des effets perturbateurs endocriniens avérés ou suspectés.
Présentation réalisée par Nicolas Bertrand, expert d'assistance à l'INRS, et présentée lors du colloque international "Substances à risques spécifiques : quels risques professionnels ? Quelle prévention ? Perturbateurs endocriniens et substances sensibilisantes." (Paris, 01-03 juin 2016)
Asbestos exposure measurement investigation using Analytical Transmission Ele...INRSfrance
2014 Conference on Monitoring and Surveillance of #Asbestos-Related Diseases.
Dimensional criteria of fibers counted in industrial hygiene have been defined by WHO as the fibers having a length greater than 5 microns, a diameter less than 3 microns and a ratio length/diameter greater than 3. But the PCM technique is limited and can only count fibers whose diameter is between 3 and 0.2 micrometers. But the asbestos fibers may have a diameter of 0.02 microns (20 nanometers) for the finest of them. With ATEM, it is possible firstly to observe thinner and smaller fibers and, above all, to differentiate asbestos fibers from other mineral fibers (by chemical analysis and electron diffraction techniques).
Managers. Comment agir face aux risques psychosociaux ?INRSfrance
Présentation destinée aux managers (chefs d'entreprise, RH, encadrement intermédiaire) pour les aider à agir au quotidien sur la prévention des risques psychosociaux
We specialise in Bioaerosols, Sick Building Syndrome, Fenceline Monitoring, Urban air quality, Industrial air quality, construction air quality, CEMS, CAMS and much more.
This handbook supports you in choosing the correct lightweight respiratory protection. It also contains usage recommendations for masks and filters. Further information can be found in the World of Respiratory Protection: https://www.draeger.com/respiratory-protection
Oxygen Reduction System N2 FIREFIGHTER® ISOLCELL SPADiego Gasser
"Completely eliminating the fire hazard and safeguarding people, buildings and it's content is possible with Isolcell's N2 Firefighter oxygen depletion systems."
Similar to Asbestos: recommendations for checking compliance with the OEL (20)
Webinaire INRS - Covid 19 : Points et conseils pour la prevention en entrepri...INRSfrance
Présentation réalisée dans le cadre d'une conférence en ligne animée par Marie-Cécile Bayeux-Dunglas, médecin, responsable du pôle risques biologiques du département Etudes et assistances médicales à l’INRS et Christine David docteur en biologie cellulaire, responsable du pôle risques biologiques du département Expertise et conseil technique de l’INRS.
En savoir plus : https://www.inrs.fr/risques/COVID19-prevention-entreprise/ce-qu-il-faut-retenir.html
Webinaire INRS - Evaluer et prevenir les risques chimiques avec Seirich - Niv...INRSfrance
Présentation effectuée par Florian Marc, expert INRS, dans le cadre d'un webinaire consacré à l'évaluation du risque chimique le 10 Décembre 2020. Destiné aux nouveaux utilisateurs potentiels du logiciel Seirich, notamment tous ceux qui débutent dans la prévention des risques chimiques, l’objectif de ce webinaire était de présenter ce que permet de faire ce logiciel et ce que nécessite sa prise en main et son utilisation
Webinaire INRS - Evaluer et prevenir le risque radon en milieu de travail - 1...INRSfrance
Présentation effectuée par Anne Bourdieu et Romain Mouillseaux, experts de la prévention du risque radon à l’INRS, dans le cadre d'un webinaire consacré à la prévention des risques professionnels liés au radon le 1er décembre 2020.
Webinaire INRS - Découvrir l’évaluation des risques chimiques avec SeirichINRSfrance
Présentation effectuée par Florian Marc, expert INRS, dans le cadre d'un webinaire consacré à l'évaluation du risque chimique le 19 novembre 2020. Destiné aux nouveaux utilisateurs potentiels du logiciel Seirich, notamment tous ceux qui débutent dans la prévention des risques chimiques, l’objectif de ce webinaire était de présenter ce que permet de faire ce logiciel et ce que nécessite sa prise en main et son utilisation.
Webinaire INRS - Travail de nuit : quels effets sur la santé ? Quelle prévent...INRSfrance
Présentation réalisée par Marie-Anne Gautier et Laurence Weibel, expertes d’assistance médicale de l’INRS, dans le cadre d'un webinaire consacré aux risques professionnels liés au travail de nuit.
Le 8 octobre 2020, l’INRS a consacré un webinaire à la fabrication additive (ou impression 3D). L’objectif était d’éclairer les entreprises sur les risques et les solutions de prévention associés à cette nouvelle technique de fabrication qui rencontre un succès grandissant dans l’industrie.
Webinaire INRS - Comprendre le role et les limites du Caces - 2 juillet 2020INRSfrance
Présentation diffusée dans le cadre d'un webinaire consacré au Caces (certificat d’aptitude à la conduite en sécurité). Ce dispositif joue un rôle clé dans l’évaluation des connaissances et du savoir-faire pour la conduite en sécurité d’engins de chantier, de levage ou de manutention.
Le séminaire en ligne était animé par Thierry Hanotel et François-Xavier Artarit, spécialistes sur ce sujet à l'INRS.
Webinaire INRS - Comment évaluer les risques psychosociaux dans les petites e...INRSfrance
Les risques psychosociaux (stress, harcèlement, agression, burnout…) doivent être évalués dans toutes les entreprises, au même titre que les autres risques. Les TPE se sentent parfois démunies face à ce sujet : Comment faire ? Par où commencer ? Qui impliquer ? L’INRS a organisé un webinaire d’une heure pour répondre à ces questions et présenter l’outil Faire le point RPS d’aide à l’évaluation des risques psychosociaux dans les petites entreprises.
Pour en savoir plus :
http://www.inrs.fr/footer/actes-evenements/webinaire-risques-psychosociaux-tpe.html
Webinaire Diagnostic d’exposition aux substances chimiques et utilisation d’A...INRSfrance
Présentation réalisée dans le cadre d'une conférence en ligne animée par Frédéric Clerc et Gautier Mater, experts de la prévention du risque chimique à l’INRS. Ce webinaire était consacré au diagnostic d’exposition et à l’utilisation d’Altrex Chimie pour l’analyse statistique des données de mesure d’exposition aux substances chimiques. Il a présenté notamment le traitement statistique des mesures d’exposition qui conduit au diagnostic de respect ou de dépassement des valeurs limite et l'intérêt d’utiliser l’application Altrex Chimie avec un exemple issu du terrain.
Webinaire Stratégie de prélèvement de polluants dans l’air des locaux de trav...INRSfrance
Présentation réalisée dans le cadre d'une conférence en ligne animée par Frédéric Clerc et Andrea Emili, experts de la prévention du risque chimique à l’INRS. Ce séminaire en ligne a proposé un point sur les enjeux, les bonnes pratiques et le détail d’un programme de contrôle normatif ou réglementaire (respect ou non des valeurs limites).
Pour visionner le webinaire : http://www.inrs.fr/footer/actes-evenements/webinaire-strategie-prelevement-atmospherique-mesure-exposition-chimique.html
Présentation réalisée Présentation réalisée par Jean Theurel et Mathilde Schwartz, experts INRS, dans le cadre d'un webinaire consacré aux exosquelettes le 28 avril 2020. L’objectif était d’informer les entreprises sur les bénéfices et les limites associés à l’usage de ces dispositifs lors de diverses tâches de manutention.
Pour en savoir plus sur les exosquelettes :
http://www.inrs.fr/risques/exosquelettes/ce-qu-il-faut-retenir.html
Webinaire Mesurer l’exposition aux substances chimiques. Principes générauxINRSfrance
Présentation réalisée par Gautier Mater et Nadia Nikolova-Pavageau, experts de la prévention du risque chimique à l’INRS dans la cadre d'un webinaire consacré au mesurage de l'exposition aux substances chimiques organisé le 12 mars 2020.
Bitume : comment améliorer la prévention du risque chimique sur les chantiers...INRSfrance
Présentation réalisée par Cosmin Patrascu (INRS) dans le cadre d'un wébinaire consacré aux risques chimiques liés à l’exposition au bitume sur les chantiers de construction routière bitume. Le séminaire en ligne organisée le 25 septembre 2018 a permis de répondre aux grandes questions qui se posent sur le sujet : quels sont les risques pour les travailleurs exposés ? Quelles sont les voies d’exposition ? Comment agir en prévention ?...
Présentation réalisée par Valérie Langevin, expert INRS, dans le cadre d'un webinaire consacré au burnout le 28 juin 2018. L'objectif était de répondre aux grandes questions qui se posent sur le burnout : que recouvre ce terme ? Quelles en sont les manifestations ? Comment le prévenir en entreprise ?
Pour visionner la vidéo du wébinaire Burnout : https://youtu.be/2SF2H53WcXY
Pour en savoir plus sur le Burnout : http://www.inrs.fr/risques/epuisement-burnout/ce-qu-il-faut-retenir.html
Présentation réalisée par Jean Theurel et Jean-Jacques Atain-Kouadio, experts INRS, dans le cadre d'un wébinaire consacré aux exosquelettes organisé le 19 juin 2018. Ces équipements font naître un espoir légitime d’amélioration des conditions de travail, mais leur utilisation nécessite de se poser les bonnes questions afin de mieux appréhender leur impact sur la santé et la sécurité des salariés.
Pour visionner la vidéo du wébinaire : https://youtu.be/qZ606vgWpoc
Pour en savoir plus sur les exosquelettes :
http://www.inrs.fr/publications/essentiels/exosquelettes.html
Présentation réalisée par Jean-Christophe Blaise, expert INRS sur la robotique collaborative, dans le cadre d'un webinaire organisé le 4 juin 2018 à destination des chefs d’entreprises, aux préventeurs et aux personnes responsables de la mise en place, de la maintenance et de la sécurité des installations robotiques collaboratives dans les usines et les ateliers.
Pour visionner la vidéo du wébinaire : https://youtu.be/aHM82350AWc
Pour en savoir plus :
http://www.inrs.fr/risques/robots-collaboratifs/ce-qu-il-faut-retenir.html
Exposition aux champs électromagnétiques : Evaluer les risques sans mesureINRSfrance
Ce document présente les notions nécessaires et utiles pour réaliser une évaluation des risques de premier niveau en utilisant l'outil OSERAY
Pour télécharger l'outil OSERAY : http://www.inrs.fr/media.html?refINRS=outil61
Présentation de Séverine Brunet, directrice des applications de l'INRS réalisée dans le cadre d'une rencontre organisée à Bruxelles par l'Agence européenne pour la sécurité et la santé au travail EU-OSHA en mai 2017. Elle présente la stratégie de l'Institut pour soutenir et accompagner la prévention des risques professionnels dans les petites entreprises. La présentation détaille également la contribution française au développement des outils OIRA d'aide à l'évaluation des risques dans les TPE-PME.
Présentation support du webinaire INRS sur l'outil MIXIE. MIXIE est un outil simple et facile à utiliser qui permet, à partir de données de mesure, d'évaluer le potentiel additif ou non des substances chimiques et de situer les niveaux d'exposition cumulés par rapport aux valeurs limites d'exposition professionnelle (VLEP).
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Nucleic Acid-its structural and functional complexity.
Asbestos: recommendations for checking compliance with the OEL
1. Asbestos: recommendations for checking compliance
with the OEL
A.Romero-Hariot, C.Eypert-Blaison, R.Vincent
Our job: making yours safer
Espoo, FINLAND – 13 February 2014
2. Background
The checking of the asbestos OEL is based on a common European
regulation
European Directive 2009/148/EC (ex-2003/18/CE) on the protection of workers
from the risks related to exposure to asbestos at work (Articles 7 and 8)
Transposed in the French Labor code regulations (R.4412-94 and following)
and several decrees
2
0.1 F.cm-3, reference time of one hour,
PCM method
1 July 2012 1 July 2015
100 F.L-1, reference time of
8 hours , ATEM method
2009 2011
10 F.L-1,
8-h, ATEM
Regulations are based on nature of
asbestos (friable or non-friable asbestos)
Regulations are based on the level of dust
generated by the process
4. European / French regulations
European Directive 2009/148/EC - Article 7 (2)
Sampling must be representative of the personal exposure of the
worker to dust arising from asbestos or materials containing asbestos
French regulations
> Dust arising from asbestos or ACM is measured in the air around the face of the worker
• Individual sampling, 30 cm maximum around the nose of the worker, each process is evaluated
• The dust level concentration is classified according to 3 levels:
> If asbestos concentration is higher than level 3, the technique must not be used because
the existing personal protective equipment cannot guarantee the protection of worker
under the OEL value
INRS recommends performing 3 personal samplings and classifying the
dust level based on the highest value 4
1
• Asbestos concentration is under OEL value
• i.e. < 100 f.L-1 until 1 July 2015, < 10 f.L-1 from 1 July 2015
2
• Asbestos concentration is above the OEL value and below 60 times the OEL value
• i.e. between 100 and 6,000 f.L-1 until 1 July 2015, and between 10 and 600 f.L-1 after this date
3
• Asbestos concentration is above 60 times the the OEL value and below 250 times the OEL value
• i.e. between 6,000 and 25,000 f.L-1 until 1 July 2015, and between 600 and 2,500 f.L-1 after this date
5. European / French regulations
European Directive 2009/148/EC - Article 7 (2)
Sampling must be representative of the personal exposure of the worker
to dust arising from asbestos or materials containing asbestos
French regulations
> Individual sampling during work situation for each process (i.e. ACM-Technique combination)
> When the worker wears a respiratory protective device, the assigned respiratory
protection factor is taken into account to calculate his exposure
5
Dust level Respiratory protective device, if dust level > 5 f.L-1 Assigned protection
factor (APF) - INRS
1st level FFP3 (only for maintenance and less than 15 mins)
Half mask with P3 filters or P3 cartridges
Full mask with P3 filters or P3 cartridges
TH3P
TM2P
TM3P
10
10 (Half mask)
30 (Full mask)
40
20
60
2nd level TM3P (160 L.min-1 flow rate)
Supplied Air Respirator (SAR) with continuous flow rate (300 L.min-1 flow rate)
Pressure-demand Supplied Air Respirator (SAR) (300 L.min-1 flow rate)
60
250
250
3rd level Supplied Air Respirator (SAR) with continuous flow rate (300 L.min-1 flow rate)
Pressure-demand Supplied Air Respirator (SAR) (300 L.min-1 flow rate)
Dustprof ventilated clothing (Nuclear clothing)
250
250
Undetermined
6. European / French regulations
European Directive 2009/148/EC – Art. 7 (3) & Art. 7 (4)
Sampling shall be carried out after consultation of the workers and/or their
representatives within the undertaking or establishment
Sampling shall be carried out by suitably qualified personnel. The samples
taken shall be subsequently analysed, in accordance with paragraph 6, in
laboratories equipped for fiber counting
French regulations
> Workers are consulted through their representatives (CHSCT)
> The sampling strategy, the sampling and the analysis are defined and conducted by an
accredited body, with the employer’s assistance
> The sampling strategy is submitted to the occupational physician
> Head quality and Laboratory responsible of the organism follow a specific training in
accordance with the accreditation requirement (COFRAC)
> ATEM indirect method for counting asbestos fibers according to the French standard NF X 43-
050 (1996) is applied
Although analysis may be entrusted to a different laboratory, INRS
recommends that the entire evaluation (strategy – sampling – analysis) be
performed by the same body in order to minimize errors at each step of the
evaluation 6