Apresentação de artigo submetido e aprovado na 25th Annual Conference of POMS (Atlanta, USA, 2014). Artigo completo disponível em http://www.pomsmeetings.org/EventsNet/?pr=1&ev=51
All you need to know about the existence and sustainability of the great Aravind eye care by Dr. V. a very comprehensive and appropriate description about this business.
IQ from a QOE: Key Considerations When Performing a Quality of Earnings Analy...PYA, P.C.
Given the complexity of healthcare’s reimbursement environment, determining the quality of reported earnings during a transaction’s due-diligence process can prove challenging. In his presentation, “IQ from a QoE: Key Considerations When Performing a Quality of Earnings Analysis Involving Healthcare Entities,” PYA Pricipal Michael Ramey introduced key considerations when planning and performing effective QoE engagements for various healthcare entities.
This paper discusses IKEA’s corporate and business level strategy and how these strategies are best supported by operations strategies of IKEA. It also discusses how IKEA differentiated itself from its competitors. Paper highlights various operational trade-offs done by company. Paper, on later stage focuses on how supply network contributed to achieving company’s objectives and strategies.
All you need to know about the existence and sustainability of the great Aravind eye care by Dr. V. a very comprehensive and appropriate description about this business.
IQ from a QOE: Key Considerations When Performing a Quality of Earnings Analy...PYA, P.C.
Given the complexity of healthcare’s reimbursement environment, determining the quality of reported earnings during a transaction’s due-diligence process can prove challenging. In his presentation, “IQ from a QoE: Key Considerations When Performing a Quality of Earnings Analysis Involving Healthcare Entities,” PYA Pricipal Michael Ramey introduced key considerations when planning and performing effective QoE engagements for various healthcare entities.
This paper discusses IKEA’s corporate and business level strategy and how these strategies are best supported by operations strategies of IKEA. It also discusses how IKEA differentiated itself from its competitors. Paper highlights various operational trade-offs done by company. Paper, on later stage focuses on how supply network contributed to achieving company’s objectives and strategies.
On the road since 1884! What today is one of the leading motor vehicle manufacturers in the world,
Piaggio is the market leader in Europe and has since expanded its services to over 50 countries with a proficient presence in the Asian markets.
ROBERTO COLNINNO is chairman and chief executive officer of piaggio and S.p.A
Ikea is reviewing its entire $444 million global media account, which is currently split between a range of agencies across five different holding companies.
Ikea is No. 66 in the ranking of Top 100 Global Marketers compiled by Ad Age's Datacenter. In 2014, the vast majority of Ikea's spending – 79% – was in Europe, with 15% in the U.S. and less than 2% in Asia.
This is a repositioning proposition we have created in IE Business School to counteract the effects of their Christmas advertisement in Milan which was branded to be 'sexist'
We were to create an IMC plan in order to execute our strategies for H&M. We created a new campaign with a "home sweet home" theme in order to expand their H&M Home line in other major cities. We also made recommendations for H&M in terms of PR, media, advertising, and etc. This is a PDF version of our IMC plan that also includes designs of our H&M Home Loyalty program cards, advertisement, and screenshot examples of social media. Template/designs by Savannah Kuang and loyalty program design by Mekynzi Sotello.
On the road since 1884! What today is one of the leading motor vehicle manufacturers in the world,
Piaggio is the market leader in Europe and has since expanded its services to over 50 countries with a proficient presence in the Asian markets.
ROBERTO COLNINNO is chairman and chief executive officer of piaggio and S.p.A
Ikea is reviewing its entire $444 million global media account, which is currently split between a range of agencies across five different holding companies.
Ikea is No. 66 in the ranking of Top 100 Global Marketers compiled by Ad Age's Datacenter. In 2014, the vast majority of Ikea's spending – 79% – was in Europe, with 15% in the U.S. and less than 2% in Asia.
This is a repositioning proposition we have created in IE Business School to counteract the effects of their Christmas advertisement in Milan which was branded to be 'sexist'
We were to create an IMC plan in order to execute our strategies for H&M. We created a new campaign with a "home sweet home" theme in order to expand their H&M Home line in other major cities. We also made recommendations for H&M in terms of PR, media, advertising, and etc. This is a PDF version of our IMC plan that also includes designs of our H&M Home Loyalty program cards, advertisement, and screenshot examples of social media. Template/designs by Savannah Kuang and loyalty program design by Mekynzi Sotello.
S.W.O.T. - Strengths, Weaknesses, Opportunities and Threats - A simple analysis focused on entrepreneurs and social media - created by Michelle Fontaine of FBSmarty. Follow us here or on Facebook (www.facebook.com/fbsmarty) and learn about our virtual courses at www.fbsmarty.com
important methods employed in quality control of ayurvedic drugsDhanya Renjith
the different methods employed these days to test the quality of ayurvedic drugs is summarised in the presentation. the presentation aims to give an awareness about basic procedures in quality control of ayurvedic drugs.
Types of Inventions; Difference between invention and innovation; Types of innovation; Innovation process vs Process innovation; Linear innovation models.. Technology push model, Market pull model; Flexible innovation process models
Early Enterprise 2.0 perspectives (circa 2005) from Stephen Danelutti of netoCiety. Essentially covers the functions of innovation and change in business transformation efforts supported by social software.
THE ENTREPRENEURIAL AND INTRAPRENEURIAL MINDFallahchay Ali
This is second chapter of Entrepreneurship and Business Planning.
The contents discusses in this chapter are as follow:
1. THE ENTREPRENEURIAL PROCESS
2. Aspects of Entrepreneurial process
3. Managerial Vs. Entrepreneurial decision making
4. CAUSES FOR INTEREST IN INTRAPRENEURIALSHIP
5. Corporate Vs. Intrapreneurial Culture
6. Climate for Intrapreneurship
7. Intrapreneurial Leadership Characteristics
8. Establishing Intrapreneurship in the Organization
I hope readers find this paper useful and enjoy from reading it.
Thank you
How to Innovate...Strategically: What Innovation Approach Should You Use When?Kevin C. Cummins
There are four common approaches to innovation that companies utilize: Lean Startup, Design-Driven, Open Innovation and Crowdsourced Idea Management. In the "How to Innovate...Strategically" presentation, we examine how and when to use each of these methods, and which companies excel at each. We uncover the limitations and the challenges when implementing each method, and the top supporting tools for each approach. View Batterii's "How to Innovate...Strategically" presentation to learn more.
Roles of a Corporate Innovation Unit - ECSI FrameworkECSI
Corporate innovation efforts at large companies often lack a clear mission
Recently, more and more companies are setting up a Corporate Innovation Unit (CIU) or similar responsibilities attached to other titles …
… however, in many situations the CIU’s role is unclear and lacks a framework to design its future state and its efforts
At the European Center for Strategic Innovation (ECSI), we have researched on the role of successful Corporate Innovation Units across various industries
Drawing on our research and consulting work, we have developed a framework that breaks the CIU’s mission down into some specific roles – or “jobs” – and provides a way to decide on what role to play, or not, and how
To introduce strategic design for an entrepreneurial venture
To discuss some of the reasons why entrepreneurs do not carry out strategic planning
To outline entrepreneurial strategy and some benefits of strategic planning
To examine the transition from an entrepreneurial style to a managerial approach
To discuss the five stages of a typical venture life cycle
To identify key management issues occurring during the growth stages
To introduce the steps useful for breaking through the growth wall
To identify the unique managerial concerns with a growth business
To elaborate the concept of entrepreneurial leadership
To outline ways to incorporate sustainability into business strategy
Reasons for failure of innovation; Economics of innovation; Importance of innovation management; Innovations strategies for a nation and an organization; Traits of innovative organizations; Types of innovative organizations; Management of innovation
Projeto de Norma de Gestão da Pesquisa, Desenvolvimento e Inovação (ABNT)Jeovan Figueiredo
Apresentação realizada durante a reunião de gestão do Fórum de Inovação da EAESP-FGV, no dia 14/09, em videoconferência. O projeto de norma de Gestão da Pesquisa, desenvolvimento e Inovação (P&D&I), proposto pela ABNT, foi apresentado e discutido pelos participantes do encontro na UFMS.
Material de apoio utilizado na capacitação "Elaboração de Projetos Inovadores", ocorrida durante o curso de extensão "Gestão Estratégica da Inovação" na UFMS em maio de 2011.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Strength and Weaknesses of Innovation Implementation
1. Strength and Weaknesses of
Innovation Implementation
Silvana Marques dos Santos Pereira - FGV
Jeovan de Carvalho - UFMS
Luiz Carlos Di Sério - FGV
POMS 25th CONFERENCE
2. Motivations
• Observations that innovations initiated with a certain strength
and by the time of launching it had lost the innovative
characteristic, a mimetic solution
• Observing literature on innovation, very little tapped on
aspects of the innovation's host: the organization
• Innovation discourse very open in a fashion way – looks good
to be innovative, but action not corresponding
2
3. Objectives
• Understand innovation process within organizations
• Comprehend the connection / disconnection between the
initial intent and the final result – the translation process into
business operation
• Case study to observe what happened during implementation
process
3
4. Research Question
• What are the factors present in the Innovation
process that generated the loss of strength of
the innovation it self?
4
6. The Process Dynamics
6
CREATION DEVELOPMENT IMPEMENTATION
Creation period in
a startup:
• bold,
• creative,
• multiple skills,
• searching for
money
Investors appear
• Professionalization
• Team Leader replaced by start up expert
• Creation replaced by management
• Risk avoidance
• Financial viability,
• Entering in the production process
The source of effectiveness in the different
stages are totally different paradigms
7. Innovation in
Organization
• The process by which innovation is internalized in companies
may be COMPLEX and PARADOXICAL:
– Organizations need to COMPETE and to do so they
innovate in many aspects.
– Organizations INTERNAL DYNAMICS, may impose
restrictions on implementation of the innovation: change
may bring a new language, a new habit or a new set of
values and underlying beliefs.
8. The Internal Mecanism
8
ROUTINE
SURVIV
AL
STABILITY
Values and organizational
rules start creating a way of
doing things that, over time,
leads to STABILITY.The stability is related to a
customary way that deals
with SURVIVAL
On a day-to-day basis
activities become
ROUTINES
Repetition of this process ensures that the group constitutes its
own ETHOS, standards, beliefs and rules of conduct
9. Stability and Survival in a
Complex Environment
• Search for stability in organizational routines
might generate:
– Fear of FAILURE of the innovation
– Difficulty to OVERCOME STABILITY
– RISK avoidance
• Tendency to seek innovation - a modern
compulsion in the search for answers in a
increasingly complex world.
10. The Survival in a Complex
Environment
• Establishes a continuous effort to decodify the elements of
innovation into established codes minimizing the impact and
adjusting the innovation to fit into already known codes.
• The greater the impact, the greater the repercussion it will
have on the environment and the greater will be the reaction
and adaptation mechanisms.
11. Reactions to Innovation
Process
11
Power
Innovation
submitted to
economic
power ,
minimize risks
ensure
viability and
financial
return.
Cultural
Occurs when
an innovation
is outside the
scope of
understanding,
comprehension
and habit of
how that
community
deals with
reality
Creating
Routine
Mechanism that
“CHEWS OVER
INNOVATION”
by creating
routine,
systematization
accommodation
Creating routine
ensures stability
12. Case Study Methodology
Chosen Case:
• A startup company in the IT sector
• Boosted by investments from a multinational group in the sector.
• Type of development: between radical and disruptive
Methodology
• Individual and group interviews , using a semi-structured script.
• The interviewees were the following groups:
– The new product/service development team
– Professionals from the purchasing organization who interfaced with the
development team
– The company’s management.
• The interviews were recorded, transcribed and subsequently analyzed.
13. Case Description
• A startup Team that developed a breakthrough idea on IT
• Looking for invertor, they end up being bought by a large IT corporation that have
a business on IT solutions in a more conservative manner
• The paradigm differences led to the hiring of a experienced professional on
startups to be the head of the project
• Started analysis of potential profitability
• Product being developed, there were instabilities on the process
• Low tolerance and decisions that could harm the project – short term financial
results expectations
• No understanding of time required for development
14. Case Description
• The Corporate Management had two nature of discourses:
1. Publicly praised the new product, thus seeking to portray an image of
modernity and innovation;
2. Privately, the discourse at the organization – ironic, contemptuous,
impatience
• The Project Team was anxious by the pressure for results/loosing face on the
success of initial intention - stress
15. Case Description
• In this context the idea is decodified for the production and commercial processes,
using the organization’s structure:
– Conflicts become more obvious
– Areas wanted to fit the project into routine and procedures
– Establish standards for repetition and production
16. Analysis of the Results
• First phase: creation
– is fluid and creative, having a multi-skilled team that has no discipline or
method.
– they look for partners and struggle to survive.
– “Angels” may appear in this phase.
• Second phase: development
– continuous struggle for investment for business is viable.
– Search to control product quality, operation standards, to be repeated.
– Various product versions and ‘debugs’ are made to prepare it for the first
contracts.
– People with professional profile, discipline and specialization are boarding in
the team
17. Typology - Interface
17
Why do they
do it?
Profile
Emotional
involvement
Propensity for
risk/
uncertainty
Passion
Ambition
Visionary
committed to
the idea
High
High
Dreamer
To share the
Dream, to
make money
Partner up to a
certain point
Medium
Medium
Angel
To earn money
Conservative
doesn't’t go in
it to loose,
control
Weak
Low
Imitation
Conservative,
follower, seeks
comfort zone
Weak
Low
Investor Parrot
Table 1 – The Dynamics between Dreamers, Investors, Parrot
18. Conclusion
• This work allowed some important points for reflection:
– Innovation seems to be important and necessary for the growth and
competitive capacity of modern organizations;
– Innovating is a growth path, but requires organization ability to deal with what
is new
– The strength or weakness here highlighted refers to the adaptation role of the
“dreamers” into the standards of the organization
– This path through which the innovation process goes through, might weaken
the innovation itself
19. ISRAEL and its Context
19
GOVERNO
Universities
Private
Sector
Angels
Investors
Army
International
Policies
Dealing with
Failure
Risk takingBreakthrough
thinking
Disruptive innovation
Startups
20. Further Steps
• Identify:
– The factors that are present in the context that
enables innovation to appear with strength, as in
Israel, Silicon Valley etc.
– The ingredients that constitute this “ecology”.
20
21. References
• Abrahamson, E. 1996. Management fashion. Academy of Management Review, 21(1): 254-285.
• Christensen, C. M. 1997. The innovator´s dilemma: when new technologies cause great firms to fail.
Boston: HBS Press.
• Gundling, E. 2000. The 3M way to innovation: balancing people and profit. Tokyo: Kodansha
International.
• Lampel, J. 2000. Product demonstrations and path creation of technological change. United
Kingdom: University of Nottingham.
• March, J, 1999. Exploration and Exploitation in Organizational Learning. In The Pursuit of
Organizational Intelligence. Oxford, Blackwell.
• Schein, E. H. 1984. Coming to a new awareness of organizational culture. Sloan Management
Review, 25(2): 3-16.
• Schumpeter, J. 2000. Entrepreneurship as innovation. In: SWEDBERG, Richard (Ed.).
Entrepreneurship: the social science view. Oxford: Oxford University Press.
• Smircich, L. 1983. Organizacional culture. Administrative Science Quarterly, 28(3): 339-358.
• Weber, M. 1999. Economia e Sociedade. Brasília: UNB.
• Wood Junior, T. Organizações Espetaculares. Rio de Janeiro: FGV, 2001.
21