Balance requires input from sensory systems like vision and vestibular, processing in the cerebellum and brainstem, and motor output. Disorders can occur from problems with input, processing, or motor function. A careful history is needed to determine the exact nature and location of dizziness or vertigo. Physical exam may reveal sensory issues, eye movement abnormalities, or weakness depending on the site of lesion. Common causes of vertigo include vestibular disorders like acute vestibular failure, benign paroxysmal positional vertigo, and Meniere's disease.
This document discusses diagnostic tools for common peripheral vestibular disorders. It describes how a thorough history, physical exam, imaging, and audio-vestibular tests are needed to accurately diagnose the underlying cause of vertigo. Specific disorders like BPPV, Meniere's disease, and vestibular neuritis are examined in terms of their characteristic symptoms, diagnostic criteria and tests. Superior semicircular canal dehiscence syndrome is also overviewed, with an emphasis on its variable clinical presentations and diagnosis using imaging and VEMP testing.
This document provides an overview of the approach to evaluating and diagnosing dizzy patients. It discusses taking a thorough history including details of episodes, performing a neurological and otological exam, and assessing eye movements, vestibular-ocular reflexes, and gait. Common causes of dizziness include peripheral issues like BPPV, Ménière's disease, and vestibular neuritis, as well as central causes like stroke and MS. Treatments for specific conditions like BPPV involve repositioning maneuvers to move canaliths like the Epley maneuver.
This document provides an overview of the medical approach to evaluating and diagnosing dizzy patients. It begins with an introduction to dizziness and vertigo. The evaluation involves taking a thorough history, performing a physical exam including tests like the Dix-Hallpike maneuver, and ordering relevant paraclinical tests. Differential diagnoses are categorized as non-systematized dizziness or vertigo, which can have peripheral or central causes. Peripheral causes of vertigo include benign paroxysmal positional vertigo and vestibular neuritis. Central causes involve the brainstem or cerebellum.
This document provides guidance from Dr. Sohrab Rabiei on evaluating patients presenting with dizziness or vertigo. It outlines the important components of the clinical history and physical examination, including tests of balance, eye movements, and hearing. Recommended testing includes lab work, imaging like CT or MRI, and vestibular function testing. The differential diagnosis should first consider whether the cause is peripheral, central or systemic. Narrowing the possibilities based on findings helps guide further investigation and diagnosis.
This document summarizes clinical tests used to examine patients presenting with vertigo. It describes tests to evaluate nystagmus including spontaneous, gaze-evoked, and positional nystagmus. Pursuit, saccadic, and vestibulo-ocular reflex testing is outlined. Positional maneuvers like Dix-Hallpike and roll tests evaluate benign paroxysmal positional vertigo. Caloric testing assesses vestibular function by irrigating each ear with warm and cold water. Together, these examinations localize pathology and differentiate peripheral from central causes of vertigo.
Approach to Dizziness and Vertigo in Emergency DepartmentFaez Toushiro
This document provides an overview of the approach to dizziness and vertigo in the emergency department. It begins with definitions and classifications of vertigo, including true vertigo versus non-vertiginous dizziness and peripheral versus central causes. The approach involves taking a thorough history to determine type and characteristics of symptoms and rule out life-threatening conditions. A physical exam includes testing of vestibular function, cranial nerves, and gait. Certain exam findings like the HINTS protocol can help differentiate peripheral from central causes. Common peripheral causes like BPPV are managed with repositioning maneuvers while other treatments include pharmacotherapy and imaging for suspected central causes.
Balance requires input from sensory systems like vision and vestibular, processing in the cerebellum and brainstem, and motor output. Disorders can occur from problems with input, processing, or motor function. A careful history is needed to determine the exact nature and location of dizziness or vertigo. Physical exam may reveal sensory issues, eye movement abnormalities, or weakness depending on the site of lesion. Common causes of vertigo include vestibular disorders like acute vestibular failure, benign paroxysmal positional vertigo, and Meniere's disease.
This document discusses diagnostic tools for common peripheral vestibular disorders. It describes how a thorough history, physical exam, imaging, and audio-vestibular tests are needed to accurately diagnose the underlying cause of vertigo. Specific disorders like BPPV, Meniere's disease, and vestibular neuritis are examined in terms of their characteristic symptoms, diagnostic criteria and tests. Superior semicircular canal dehiscence syndrome is also overviewed, with an emphasis on its variable clinical presentations and diagnosis using imaging and VEMP testing.
This document provides an overview of the approach to evaluating and diagnosing dizzy patients. It discusses taking a thorough history including details of episodes, performing a neurological and otological exam, and assessing eye movements, vestibular-ocular reflexes, and gait. Common causes of dizziness include peripheral issues like BPPV, Ménière's disease, and vestibular neuritis, as well as central causes like stroke and MS. Treatments for specific conditions like BPPV involve repositioning maneuvers to move canaliths like the Epley maneuver.
This document provides an overview of the medical approach to evaluating and diagnosing dizzy patients. It begins with an introduction to dizziness and vertigo. The evaluation involves taking a thorough history, performing a physical exam including tests like the Dix-Hallpike maneuver, and ordering relevant paraclinical tests. Differential diagnoses are categorized as non-systematized dizziness or vertigo, which can have peripheral or central causes. Peripheral causes of vertigo include benign paroxysmal positional vertigo and vestibular neuritis. Central causes involve the brainstem or cerebellum.
This document provides guidance from Dr. Sohrab Rabiei on evaluating patients presenting with dizziness or vertigo. It outlines the important components of the clinical history and physical examination, including tests of balance, eye movements, and hearing. Recommended testing includes lab work, imaging like CT or MRI, and vestibular function testing. The differential diagnosis should first consider whether the cause is peripheral, central or systemic. Narrowing the possibilities based on findings helps guide further investigation and diagnosis.
This document summarizes clinical tests used to examine patients presenting with vertigo. It describes tests to evaluate nystagmus including spontaneous, gaze-evoked, and positional nystagmus. Pursuit, saccadic, and vestibulo-ocular reflex testing is outlined. Positional maneuvers like Dix-Hallpike and roll tests evaluate benign paroxysmal positional vertigo. Caloric testing assesses vestibular function by irrigating each ear with warm and cold water. Together, these examinations localize pathology and differentiate peripheral from central causes of vertigo.
Approach to Dizziness and Vertigo in Emergency DepartmentFaez Toushiro
This document provides an overview of the approach to dizziness and vertigo in the emergency department. It begins with definitions and classifications of vertigo, including true vertigo versus non-vertiginous dizziness and peripheral versus central causes. The approach involves taking a thorough history to determine type and characteristics of symptoms and rule out life-threatening conditions. A physical exam includes testing of vestibular function, cranial nerves, and gait. Certain exam findings like the HINTS protocol can help differentiate peripheral from central causes. Common peripheral causes like BPPV are managed with repositioning maneuvers while other treatments include pharmacotherapy and imaging for suspected central causes.
Vertigo is a common symptom that affects approximately 30% of people at some point in their life. There are many potential causes of vertigo, including benign paroxysmal positional vertigo (BPPV), vestibular neuritis, Meniere's disease, and less commonly central nervous system disorders. A thorough history, physical exam including tests of ocular motor function and positional maneuvers, and occasionally neuroimaging can help identify the underlying cause in most patients. The most common peripheral vestibular disorders like BPPV and vestibular neuritis are usually self-limited and the main treatment is symptomatic.
1) The document discusses various approaches to evaluating and treating vertigo, including distinguishing between peripheral and central causes.
2) Diagnostic tests like Dix-Hallpike, VNG, and HINTS can help determine if vertigo is peripheral or central in nature and identify specific causes.
3) Treatment depends on the underlying cause but may include medications, repositioning maneuvers, vestibular rehabilitation, and in rare cases surgery.
The document discusses dizziness, its types (vertigo, disequilibrium, pre-syncope, syncope), common causes, diagnostic approach, examination findings, investigations, and treatment. The diagnostic approach involves taking a thorough history and conducting physical examinations like neurological and vestibular tests. Common causes include peripheral vestibular disorders, central nervous system issues, and psychiatric conditions. Treatment is directed at the underlying cause, which may include medication, repositioning procedures, rehabilitation therapy, or lifestyle changes.
This document discusses the assessment of a 62-year-old male patient presenting with acute vertigo. On examination, he displayed nystagmus, trunk instability, and loss of hearing in his right ear. Imaging showed a transverse petrous fracture involving the labyrinth and semicircular canals. The differential diagnosis includes peripheral vestibular disorders like vestibular neuritis and central causes like stroke. A careful history and examination can help differentiate between peripheral and central causes of vertigo.
HOW TO MANAGE PATIENTS WITH VERTIGO?
Andradi S.
Department of Neurology. University of Indonesia, Jakarta
disampaikan dalam Simposium PIT IDI Kota Bogor
This document discusses testing of vestibular function. It begins by providing statistics on dizziness complaints. The rest of the document describes various office examinations and tests that can be used to evaluate vestibular function, including cranial nerve exams, positional tests like Dix-Hallpike and Fukuda stepping, and oculomotor function tests like head thrust and head shake nystagmus. It then reviews quantitative vestibular testing methods like electronystagmography (ENG), which can test individual labyrinths, and rotational chair testing, which is considered the gold standard for identifying bilateral vestibular lesions.
This document provides an overview of evaluating patients presenting with dizziness or vertigo. It discusses classifying vertigo based on duration, whether it is central or peripheral in origin, and non-vestibular causes. A thorough history and physical exam including neurologic and vestibular testing is outlined. Key diagnostic tests like Dix-Hallpike, caloric testing, and VEMP are described. Common causes of vertigo like BPPV, vestibular neuronitis, and Meniere's disease are highlighted based on presenting symptoms, exam findings, and test results.
Vertigo is a problem commonly encountered in daily clinical practice.So an uniform approach to a patient with Vertigo is essential to identify the underlying aetiology of Vertigo.
A 40-year-old man presented with worsening episodes of rotational vertigo for the last 2 weeks. He reports a history of similar episodes starting 8 years ago, initially occurring every 2-3 months and lasting 1-2 hours, resolving with sleep. Recently the episodes increased in frequency to weekly, then daily, and were no longer resolving with sleep. Examination findings were normal. He was referred to neurology for suspected vestibular migraine based on his history and lack of improvement with previous treatments. Vestibular migraine is one of the most common causes of vertigo and can present with episodic vertigo, positional vertigo, and constant imbalance. Diagnosis is based on history in the absence of abnormal examination findings
Central neurogenic vertigo can have various causes in both children and adults. In children, the most common cause is migraine, affecting about 35% of cases. In adults, common causes include vascular issues like vertebrobasilar insufficiency, migraines, Meniere's disease, benign positional vertigo, cervical spondylosis, and less commonly tumors or multiple sclerosis. Thorough neurological examination and sometimes imaging tests are needed to determine the underlying cause in both peripheral and central vertigo cases.
Vertigo and peripheral vestibular disordersbehrouz barati
This document discusses vertigo, providing information on:
1) Differential diagnoses for vertigo including peripheral vestibular dysfunction, central brainstem lesions, presyncope, psychiatric disorders, and unknown causes.
2) Peripheral vs central causes of vertigo based on factors like onset, severity, positional nature, intermittency, and presence of nystagmus, otologic, or neurologic findings.
3) Common peripheral causes of vertigo including BPPV (canalithiasis), vestibular neuronitis, Meniere's disease, and trauma. Common central causes include vascular issues and demyelinating diseases.
The vestibular system is responsible for the maintenance of balance in human beings. The basic anatomy consists of bony structures called bony labyrinthine and membranous labyrinthine. The receptors consists of utricle and saccule. The fluid filled within the internal ear called endolymph. The basic physiology of macula, cristae and supporting structures are explained in the presentation.
This presentation deals with the various physical tests used to assess the vestibular system and which can be used as an outcome measures like:
a. Caloric Test
b. Dizziness Handicap Inventory scale
c. Head Impulse Test
d. Head shaking induces nystagmus
e. Dix- Hallpike Test
f. Dynamic Visual Acuity Test
g. Rotational Chair Test
h. Romberg Test
The document discusses dizziness and vertigo, their causes, and treatment options. It outlines that 85% of vertigo is caused by inner ear problems, including Meniere's disease, vestibular neuritis, and benign paroxysmal positional vertigo (BPPV). BPPV is the most common cause of vertigo and can be treated through repositioning maneuvers to move calcium carbonate crystals that have migrated to the wrong part of the inner ear. Vestibular rehabilitation exercises can help adapt to inner ear problems and reduce dizziness and imbalance.
Vertigo is a subtype of dizziness in which a patient inappropriately experiences the perception of motion (usually a spinning motion) due to dysfunction of the vestibular system.
This document provides information on dizziness and balance disorders from Dr. Zuraida Zainun, a senior lecturer in audiology. It includes definitions of dizziness, descriptions of different dizziness subtypes, factors to consider in the history and examination of patients with dizziness, details on various vestibular and balance tests, differential diagnoses, and concepts of management including vestibular rehabilitation exercises and follow up. References are also provided on topics related to dizziness and balance disorders.
The document discusses various clinical and laboratory methods used to assess the vestibular system. Clinical methods include tests of spontaneous nystagmus, the fistula test, Romberg test, gait, past-pointing and falling, and the Hallpike maneuver. Laboratory methods include the caloric test, electronystagmography, optokinetic test, rotation test, and posturography. The document then provides detailed descriptions of procedures and indications for spontaneous nystagmus, the fistula test, Romberg test, past-pointing and falling test, and the Hallpike maneuver. Characteristics of peripheral and central nystagmus are also compared.
This document provides guidelines for writing a medical case report, including its typical structure and content. It describes the 7 main sections of a case report: 1) patient identification data, 2) medical history, 3) physical examination, 4) investigation data, 5) clinical diagnosis, 6) substantiation of the basic diagnosis, and 7) pathogenesis of symptoms and signs. Each section is explained in detail, outlining the key information that should be included about the patient's history, examination findings, test results, diagnosis, evidence supporting the diagnosis, and pathogenesis of observed signs and symptoms. The document aims to teach students the proper format for documenting a patient's medical case.
This study investigated the prevalence of four otologic (ear-related) complaints (otalgia, tinnitus, vertigo, hearing loss) in 200 patients with temporomandibular disorder (TMD) and compared it to a control group without TMD. The study found that TMD patients reported significantly higher rates of otologic complaints than the control group, with over three-quarters of TMD patients reporting at least one complaint. Otalgia was the most commonly reported complaint across the different TMD subgroups. However, there were only a small number of patients that had objective evidence of hearing loss related to their subjective complaints. The study suggests TMD may be associated with increased reports of otologic symptoms.
Vertigo is a common symptom that affects approximately 30% of people at some point in their life. There are many potential causes of vertigo, including benign paroxysmal positional vertigo (BPPV), vestibular neuritis, Meniere's disease, and less commonly central nervous system disorders. A thorough history, physical exam including tests of ocular motor function and positional maneuvers, and occasionally neuroimaging can help identify the underlying cause in most patients. The most common peripheral vestibular disorders like BPPV and vestibular neuritis are usually self-limited and the main treatment is symptomatic.
1) The document discusses various approaches to evaluating and treating vertigo, including distinguishing between peripheral and central causes.
2) Diagnostic tests like Dix-Hallpike, VNG, and HINTS can help determine if vertigo is peripheral or central in nature and identify specific causes.
3) Treatment depends on the underlying cause but may include medications, repositioning maneuvers, vestibular rehabilitation, and in rare cases surgery.
The document discusses dizziness, its types (vertigo, disequilibrium, pre-syncope, syncope), common causes, diagnostic approach, examination findings, investigations, and treatment. The diagnostic approach involves taking a thorough history and conducting physical examinations like neurological and vestibular tests. Common causes include peripheral vestibular disorders, central nervous system issues, and psychiatric conditions. Treatment is directed at the underlying cause, which may include medication, repositioning procedures, rehabilitation therapy, or lifestyle changes.
This document discusses the assessment of a 62-year-old male patient presenting with acute vertigo. On examination, he displayed nystagmus, trunk instability, and loss of hearing in his right ear. Imaging showed a transverse petrous fracture involving the labyrinth and semicircular canals. The differential diagnosis includes peripheral vestibular disorders like vestibular neuritis and central causes like stroke. A careful history and examination can help differentiate between peripheral and central causes of vertigo.
HOW TO MANAGE PATIENTS WITH VERTIGO?
Andradi S.
Department of Neurology. University of Indonesia, Jakarta
disampaikan dalam Simposium PIT IDI Kota Bogor
This document discusses testing of vestibular function. It begins by providing statistics on dizziness complaints. The rest of the document describes various office examinations and tests that can be used to evaluate vestibular function, including cranial nerve exams, positional tests like Dix-Hallpike and Fukuda stepping, and oculomotor function tests like head thrust and head shake nystagmus. It then reviews quantitative vestibular testing methods like electronystagmography (ENG), which can test individual labyrinths, and rotational chair testing, which is considered the gold standard for identifying bilateral vestibular lesions.
This document provides an overview of evaluating patients presenting with dizziness or vertigo. It discusses classifying vertigo based on duration, whether it is central or peripheral in origin, and non-vestibular causes. A thorough history and physical exam including neurologic and vestibular testing is outlined. Key diagnostic tests like Dix-Hallpike, caloric testing, and VEMP are described. Common causes of vertigo like BPPV, vestibular neuronitis, and Meniere's disease are highlighted based on presenting symptoms, exam findings, and test results.
Vertigo is a problem commonly encountered in daily clinical practice.So an uniform approach to a patient with Vertigo is essential to identify the underlying aetiology of Vertigo.
A 40-year-old man presented with worsening episodes of rotational vertigo for the last 2 weeks. He reports a history of similar episodes starting 8 years ago, initially occurring every 2-3 months and lasting 1-2 hours, resolving with sleep. Recently the episodes increased in frequency to weekly, then daily, and were no longer resolving with sleep. Examination findings were normal. He was referred to neurology for suspected vestibular migraine based on his history and lack of improvement with previous treatments. Vestibular migraine is one of the most common causes of vertigo and can present with episodic vertigo, positional vertigo, and constant imbalance. Diagnosis is based on history in the absence of abnormal examination findings
Central neurogenic vertigo can have various causes in both children and adults. In children, the most common cause is migraine, affecting about 35% of cases. In adults, common causes include vascular issues like vertebrobasilar insufficiency, migraines, Meniere's disease, benign positional vertigo, cervical spondylosis, and less commonly tumors or multiple sclerosis. Thorough neurological examination and sometimes imaging tests are needed to determine the underlying cause in both peripheral and central vertigo cases.
Vertigo and peripheral vestibular disordersbehrouz barati
This document discusses vertigo, providing information on:
1) Differential diagnoses for vertigo including peripheral vestibular dysfunction, central brainstem lesions, presyncope, psychiatric disorders, and unknown causes.
2) Peripheral vs central causes of vertigo based on factors like onset, severity, positional nature, intermittency, and presence of nystagmus, otologic, or neurologic findings.
3) Common peripheral causes of vertigo including BPPV (canalithiasis), vestibular neuronitis, Meniere's disease, and trauma. Common central causes include vascular issues and demyelinating diseases.
The vestibular system is responsible for the maintenance of balance in human beings. The basic anatomy consists of bony structures called bony labyrinthine and membranous labyrinthine. The receptors consists of utricle and saccule. The fluid filled within the internal ear called endolymph. The basic physiology of macula, cristae and supporting structures are explained in the presentation.
This presentation deals with the various physical tests used to assess the vestibular system and which can be used as an outcome measures like:
a. Caloric Test
b. Dizziness Handicap Inventory scale
c. Head Impulse Test
d. Head shaking induces nystagmus
e. Dix- Hallpike Test
f. Dynamic Visual Acuity Test
g. Rotational Chair Test
h. Romberg Test
The document discusses dizziness and vertigo, their causes, and treatment options. It outlines that 85% of vertigo is caused by inner ear problems, including Meniere's disease, vestibular neuritis, and benign paroxysmal positional vertigo (BPPV). BPPV is the most common cause of vertigo and can be treated through repositioning maneuvers to move calcium carbonate crystals that have migrated to the wrong part of the inner ear. Vestibular rehabilitation exercises can help adapt to inner ear problems and reduce dizziness and imbalance.
Vertigo is a subtype of dizziness in which a patient inappropriately experiences the perception of motion (usually a spinning motion) due to dysfunction of the vestibular system.
This document provides information on dizziness and balance disorders from Dr. Zuraida Zainun, a senior lecturer in audiology. It includes definitions of dizziness, descriptions of different dizziness subtypes, factors to consider in the history and examination of patients with dizziness, details on various vestibular and balance tests, differential diagnoses, and concepts of management including vestibular rehabilitation exercises and follow up. References are also provided on topics related to dizziness and balance disorders.
The document discusses various clinical and laboratory methods used to assess the vestibular system. Clinical methods include tests of spontaneous nystagmus, the fistula test, Romberg test, gait, past-pointing and falling, and the Hallpike maneuver. Laboratory methods include the caloric test, electronystagmography, optokinetic test, rotation test, and posturography. The document then provides detailed descriptions of procedures and indications for spontaneous nystagmus, the fistula test, Romberg test, past-pointing and falling test, and the Hallpike maneuver. Characteristics of peripheral and central nystagmus are also compared.
This document provides guidelines for writing a medical case report, including its typical structure and content. It describes the 7 main sections of a case report: 1) patient identification data, 2) medical history, 3) physical examination, 4) investigation data, 5) clinical diagnosis, 6) substantiation of the basic diagnosis, and 7) pathogenesis of symptoms and signs. Each section is explained in detail, outlining the key information that should be included about the patient's history, examination findings, test results, diagnosis, evidence supporting the diagnosis, and pathogenesis of observed signs and symptoms. The document aims to teach students the proper format for documenting a patient's medical case.
This study investigated the prevalence of four otologic (ear-related) complaints (otalgia, tinnitus, vertigo, hearing loss) in 200 patients with temporomandibular disorder (TMD) and compared it to a control group without TMD. The study found that TMD patients reported significantly higher rates of otologic complaints than the control group, with over three-quarters of TMD patients reporting at least one complaint. Otalgia was the most commonly reported complaint across the different TMD subgroups. However, there were only a small number of patients that had objective evidence of hearing loss related to their subjective complaints. The study suggests TMD may be associated with increased reports of otologic symptoms.
This document provides information on dizziness and vestibular testing. It includes a biography of Dr. Zuraida Zainun, an audiology expert. The document discusses taking a history for dizziness, differential diagnoses, types of dizziness sensations, characteristics of peripheral versus central vertigo, and clinical examinations. It also outlines vestibular tests like VNG, VEMP, and rotating chair, as well as rehabilitation strategies and references.
This document discusses temporomandibular joint disorder (TMJD). It begins by defining TMJD as a collective term for clinical problems involving the temporomandibular joints and associated muscles. The document then covers the anatomy of the TMJ, epidemiology of TMJDs, assessment methods, classifications of TMJD types, and treatments. Key points include that TMJDs are most common in young and middle-aged adults, especially women, and that assessments involve patient history, physical examinations of the jaw, and sometimes imaging tests. The classifications section distinguishes between subtypes of TMJD like joint pain, arthritis, and disc displacement disorders.
This document provides an overview of obstructive sleep apnea (OSA), including its causes, symptoms, diagnosis, and management options. It discusses that OSA is characterized by repetitive collapse of the upper airway during sleep, disrupting breathing. Risk factors include obesity, male gender, age, and craniofacial abnormalities. Diagnosis involves questionnaires, physical exams, and polysomnography. Treatment includes positive airway pressure and oral appliances, which work by advancing the mandible to open the airway. Oral appliances effectively treat mild to moderate OSA and reduce snoring but have side effects like teeth pain that require follow-up.
This document provides guidance on evaluating head and cervical spine injuries using radiology. It outlines the key things to look for on head CT scans such as fractures, hemorrhages and strokes. For cervical spine exams, it recommends standard radiograph views and describes cervical spine anatomy and specific fracture patterns like teardrop fractures and hangman's fractures. It also discusses evaluating cervical spine alignment and measures like the atlanto-dens interval on radiographs and the risks of vertebral artery injuries.
- Dystonia is estimated to affect 16.4 per 100,000 people worldwide. A study in India found a prevalence of 43.91 per 100,000 for primary dystonias.
- Primary dystonias are more common than secondary dystonias. Common causes of secondary dystonia include infections, hypoxia, trauma, and kernicterus.
- Dystonia presents with sustained muscle contractions causing abnormal postures or repetitive movements. It can be initiated or worsened by voluntary actions and often involves overflow to nearby muscles.
This Volume of Progress in Clinical Neurosciences brings to you a synthesized overview of clinically relevant topics in an easy-to-read format. It would enable both the practicing Clinician and the student in training to update their knowledge and apply it in day-to-day practice. The most significant advances in traumatic brain injury, pituitary adenomas, myasthenia gravis, epilepsy source localization, and poststroke rehabilitation have been addressed. The controversies regarding the management of low grade gliomas, solitary brain metastasis and optimal surgical approach to colloid cysts are discussed cogently. A systematic diagnostic approach to myelopathy and encephalopathy is illustrated. The future of neurosurgical education is simulation and there is a detailed explanation of this strategy. The importance and relevance of clinical examination in today's era of highly advanced diagnostic imaging cannot be understated and this has been put forth emphatically.
This document provides guidelines for preoperative patient assessment and fasting. It outlines conducting a thorough history and physical exam to determine the patient's surgical risks and optimize perioperative care. Key parts of the assessment include the patient's medical history, medications, allergies, review of systems, and fitness classification. Recommended preoperative tests vary based on the patient and surgery. Fasting guidelines differentiate clear liquids, which require only a 2 hour fast, from solid foods and milk requiring at least a 6 hour fast prior to anesthesia.
Vertigo is a common complaint that requires differentiating between central and peripheral causes. A thorough history and physical exam, including HINTS testing, is needed. Peripheral vertigo is often benign and can be treated with repositioning maneuvers like Epley's or Sermont's for conditions like BPPV. Central vertigo requires imaging to rule out serious conditions like stroke. Short term medication may help peripheral symptoms but definitive treatment is repositioning or management of underlying disorders. Proper evaluation is key to differentiating benign from potentially life-threatening causes of vertigo.
This document provides an overview of the approach to treating emergency patients. It discusses conducting a primary survey following the ABCDE method to assess the airway, breathing, circulation, disability, and exposure. This is followed by taking a history, secondary survey, ordering relevant tests, providing treatment for life-threatening issues, and reevaluating the patient. Key areas covered include managing the airway, treating pneumothorax, hemorrhage control, head injury assessment, and the importance of spinal immobilization.
This document provides guidelines for evaluating and managing patients presenting with syncope. It defines syncope and differentiates it from other transient loss of consciousness conditions. Syncope is categorized into three major types - neurally-mediated, orthostatic hypotension, and cardiovascular-mediated. The guidelines recommend a systematic approach involving identifying life-threatening causes, evaluating for etiology, and risk stratifying patients if the cause remains unclear. Key aspects of history taking and physical exam are outlined to help identify potential causes. Recommended tests include ECG, cardiac monitoring, echocardiogram, and tilt table testing depending on patient characteristics and presentation.
1. The document reviews literature on photic stimulation procedures during EEG and discusses technical considerations, methodology, human factors, and expert recommendations over time.
2. It provides details on exclusion criteria, equipment, procedures, responses to abnormal EEG changes during stimulation, and emphasizes obtaining proper informed consent and having protocols for safety and dealing with potential seizures.
3. Expert consensus groups have aimed to standardize photic stimulation protocols and emphasize assessing risks prior to the procedure, using appropriate flash rates and intensities, and stopping immediately if generalized discharges occur.
Role of the new imaging modalities in the investigation of meniere diseaseCristian Yañez
The study evaluated imaging findings in 23 patients with definite Meniere's disease (MD) compared to 50 control subjects. High-resolution CT scans found that the vestibular aqueduct (VA) was nonvisualized more frequently in the MD group (27.8% of diseased ears vs 3.4% in controls), as was the endolymphatic duct-endolymphatic sac complex on MRI (39.1% vs 64.1%). Pneumatization around the VA was also lower in the MD group. The results suggest impaired flow of endolymph toward the endolymphatic sac may be involved in the pathophysiology of MD at different disease stages.
This document summarizes a case series study on the role of microbes in chronic suppurative otitis media (CSOM) - atticoantral disease. The study included 50 CSOM patients who underwent ear swab cultures before surgery and specimen cultures during surgery. Pseudomonas species and Staphylococcus were found to be the most common microorganisms in both preoperative and operative samples. The samples collected preoperatively and during surgery were found to be similar in over 80% of cases. The study aimed to explore relationships between preoperative cultures and intraoperative specimens in CSOM.
This document discusses the evaluation and management of pediatric airway stenosis. It notes that congenital laryngeal anomalies account for 60% of cases of stridor in children. Laryngomalacia is the most common congenital laryngeal disorder, affecting 60% of cases. Subglottic stenosis accounts for 20% of congenital laryngeal disorders. Rigid bronchoscopic evaluation is important for diagnosis. Endoscopic management is recommended when possible but has a higher risk of failure for more severe cases. Open procedures like anterior cricoid splitting or laryngotracheal reconstruction with cartilage grafts may be needed for severe subglottic stenosis or posterior glottic stenosis. A team approach is important for successful management.
16001107 01 X Stop Surgeon To Patient FinalWilliamYoungMD
This document summarizes lumbar spinal stenosis, including its symptoms, treatment options, and a new minimally invasive treatment called the X-STOP spacer. Lumbar spinal stenosis causes back and leg pain due to narrowing of the spinal canal. Treatment options discussed include non-operative care, laminectomy, and the X-STOP procedure, which separates the spinous processes with an implanted spacer to relieve pressure on nerves. The X-STOP procedure provides relief of symptoms with less risks and recovery time compared to laminectomy.
The report about osteopathy and postural function in dentistryAlexander Budovsky
The interdisciplinary approach is becoming more widely used by modern Russian dentistry. This approach covers both dentistry disciplines and general medical field. It often leads to hyper diagnostics and inadequate treatment, with results in a patient’s overtreatment and their psychological state.
Osteopathy has gained a lot of popularity, especially cranio-osteopathy, to treat patients with TMD (TemporoMandibular Disorders). It becomes obvious that the relation between supporting-motor apparatus and masticatory system evokes great interest.
Some authors claim that TMD is caused by poor posture and spine disorders but not by problems in maxillofacial area.
Many scientific conferences have been held all over the world. A lot of clinics have taken on osteopaths.
The use of alternative medicine techniques in our field is very risky as no enough scientific evidence has been found yet to prove the effectiveness of such methods of treatment.
The aim of our research is to determine the effectiveness of the use of cranio-osteopathic methods in dentistry field.
low birth weight presentation. Low birth weight (LBW) infant is defined as the one whose birth weight is less than 2500g irrespective of their gestational age. Premature birth and low birth weight(LBW) is still a serious problem in newborn. Causing high morbidity and mortality rate worldwide. The nursing care provide to low birth weight babies is crucial in promoting their overall health and development. Through careful assessment, diagnosis,, planning, and evaluation plays a vital role in ensuring these vulnerable infants receive the specialize care they need. In India every third of the infant weight less than 2500g.
Birth period, socioeconomical status, nutritional and intrauterine environment are the factors influencing low birth weight
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Lecture 6 -- Memory 2015.pptlearning occurs when a stimulus (unconditioned st...AyushGadhvi1
learning occurs when a stimulus (unconditioned stimulus) eliciting a response (unconditioned response) • is paired with another stimulus (conditioned stimulus)
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
Approach to vertigo
1. Sasan Dabiri, MD, Associate Professor
Department of Otorhinolaryngology – Head & Neck Surgery
Amir Alam Hospital – Tehran University of Medical Sciences
I ra n i a n E N T S o c i e t y Pa n e l D i s c u s s i o n
J u l y 2 0 1 9
2. Iranian ENT Society Panel Discussion : Vestibular Migraine
Vertigo
Presyncope
Disequilibrium
Psychiatric
Not
specific
Dizziness - Etiology
Vertigo: Diagnostic Approach
3. Iranian ENT Society Panel Discussion : Vestibular Migraine
Vertigo
Presyncope
Disequilibrium
Psychiatric
Not
specific
Dizziness - Etiology
Peripheral
Central
Dizziness - Etiology
Vertigo: Diagnostic Approach
4. Iranian ENT Society Panel Discussion : Vestibular Migraine
Vertigo
Presyncope
Disequilibrium
Psychiatric
Not
specific
Dizziness - Etiology
Peripheral
Central
Dizziness - Etiology
Vertigo: Diagnostic Approach
5. Iranian ENT Society Panel Discussion : Vestibular Migraine
Vertigo: Diagnostic Approach
T h e accurate diagnosis of th e u n d erlyin g etiology
is th e crucial step in th e man agement of vertigo
6. Iranian ENT Society Panel Discussion : Vestibular Migraine
Imaging
Audio-
Vestibular
Tests
Physical
Exam.
History
Vertigo: Diagnostic Approach
T h e accurate diagnosis of th e u n d erlyin g etiology
is th e crucial step in th e man agement of vertigo
7. Iranian ENT Society Panel Discussion : Vestibular Migraine
Imaging
Audio-
Vestibular
Tests
Physical
Exam.
History
Vertigo: Diagnostic Approach
T h e accurate diagnosis of th e u n d erlyin g etiology
is th e crucial step in th e man agement of vertigo
8. Iranian ENT Society Panel Discussion : Vestibular Migraine
Imaging
Audio-
Vestibular
Tests
Physical
Exam.
History
Vertigo: Diagnostic Approach
T h e accurate diagnosis of th e u n d erlyin g etiology
is th e crucial step in th e man agement of vertigo
9. Iranian ENT Society Panel Discussion : Vestibular Migraine
Imaging
Audio-
Vestibular
Tests
Physical
Exam.
History
T h e accurate diagnosis of th e u n d erlyin g etiology
is th e crucial step in th e man agement of vertigo
Vertigo: Diagnostic Approach
10. Iranian ENT Society Panel Discussion : Vestibular Migraine
History
True or pseudo-vertigo
One attack or more
Episodic or continuous
Duration of each episode
Chronology of symptoms
How does start at first time
(straining, trauma)
Associated symptoms (oto, neuro, ocular)
Associated histories
(medico-surgical, family, drug, psychologic)
Effect of life style
environment
Effect of head movement
ear pressure changes
Vertigo: Diagnostic Approach
11. Iranian ENT Society Panel Discussion : Vestibular Migraine
Ear Exam (inspection)
Eye Exam (position & Nystagmus)
Neurologic Exam (R/O ataxia)
Sound or Pressure (3rd window)
Vibration (SSCD, MD, VS)
Hyperventilation (phobia, central)
demyelination: MS, VS, Vascular
Positional testing (Hallpike , roll test)
H I T test (canal dysfunction)
Head shaking test
Physical
Exam.
History
Vertigo: Diagnostic Approach
12. Iranian ENT Society Panel Discussion : Vestibular Migraine
Audio-
Vestibular
Tests
Physical
Exam.
History
VNG (saccade , pursuit , nystagmus )
Evoked evaluation
• Caloric Test ( lower freq. )
• Head Shaking ( 1-2 Hz )
• V-HIT ( 3-5 Hz )
Rotatory chair test
Posturography ( C D P )
PTA-SRT-WRS, AR
ECoG
VEMP (cervical, ocular)
Vertigo: Diagnostic Approach
13. Iranian ENT Society Panel Discussion : Vestibular Migraine
Imaging
Audio-
Vestibular
Tests
Physical
Exam.
History
C T :
• Otic capsule involvement
• SSCD Sx. / any other 3rd window
• Large vestibular aqueduct Sx.
M R :
• Meniere’s Disease
• CP Angle lesions
• Other central disorders
Vertigo: Diagnostic Approach
14. Iranian ENT Society Panel Discussion : Vestibular Migraine
Imaging
Audio-
Vestibular
Tests
Physical
Exam.
History
Concurrent disorders might b e p res ent in th e s ame time
Patients with vertigo h ave s ome d egree of pseudo-vertigo
T h e etiology might change d u rin g time
Vertigo: Diagnostic Approach
15. Iranian ENT Society Panel Discussion : Vestibular Migraine
References
• Rose BD et al. UpToDate. http://www.uptodate.com/contents/search (last seen: Oct. 2016)
• Approach to the patient with dizziness
• Evaluation of the patient with vertigo
• Pathophysiology, etiology, and differential diagnosis of vertigo
• Overview of nystagmus
• Pharmacologic use of glucocorticoids
• Flint PW et al. Cummings Otolaryngology - Head & Neck Surgery, 6th ed. (2015)
• Principles of applied vestibular physiology
• Evaluation of the patient with dizziness
• Peripheral vestibular disorders
• Surgery for vestibular disorders
• Bronstein AM et al. Oxford Textbook of Vertigo and Imbalance. 1st ed. (2013)
• Hain TC. MRI Imaging of Meniere's Disease/Syndrome. http://www.dizziness-and-balance.com/disorders/
menieres/mri-hydrops.html (last modified: Jul. 2016)
• Baráth K et al. Detection and Grading of Endolymphatic Hydrops in Meniere Disease Using MR
Imaging. Am J Neuroradiol 2014; 35: 1-6
• Curthoys IS. The Interpretation of Clinical Tests of Peripheral Vestibular Function. Laryngoscope 2012;
122: 1342–52
• … and some web sources for photos