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APPROACH TO PATIENTS WITH
MINOR HEAD INJURY
Dr SAMEEP KOSHTI
MILD TRAUMATIC BRAIN INJURY
(M-TBI)
• Definition
• Scales
• Signs and symptoms
• Prehospital management of traumatic brain injury
• Management in ED/Triage
• Requirement of Imaging :?:
• Admission or safe discharge?
• Treatment
• Sequelae
• Post injury Neuropsychology and rehabilitation
WHO DEFINITION
• Mild TBI is an acute brain injury resulting from
mechanical energy to the head from external physical
forces.
• Operational criteria for clinical identification include:
– (i) 1 or more of the following:
• confusion or disorientation,
• loss of consciousness for 30 minutes or less,
• post-traumatic amnesia for less than 24 hours, and/or
• Other transient neurological abnormalities such as focal signs,
seizure, and intracranial lesion not requiring surgery;
– (ii) Glasgow Coma Scale score of 13-15 after 30 minutes
post-injury or later upon presentation for health care.
Contd..
• These manifestations of MTBI must not be due
to :
– drugs, alcohol, medications,
– caused by other injuries or treatment for other
injuries (e.g. systemic injuries, facial injuries or
intubation),
– caused by other problems (e.g. psychological
trauma, language barrier or coexisting medical
conditions) or
– caused by penetrating craniocerebral injury.
Concussion definition
• A complex pathophysiological process affecting the brain, induced by biomechanical forces.
• Several common features that incorporate clinical, pathologic and biomechanical injury
constructs that may be utilized in defining the nature of a concussive head injury include:
• 1. Concussion may be caused either by a direct blow to the head, face, neck or elsewhere on
the body with an “impulsive” force transmitted to the head.
• 2. Concussion typically results in the rapid onset of short-lived impairment of neurological
function that resolves spontaneously. However, in some cases, symptoms and signs may
evolve over a number of minutes to hours.
• 3. Concussion may result in neuropathological changes, but the acute clinical symptoms
largely reflect a functional disturbance rather than a structural injury and, as such, no
abnormality is seen on standard structural neuroimaging studies.
• 4. Concussion results in a graded set of clinical symptoms that may or may not involve loss
of consciousness. Resolution of the clinical and cognitive symptoms typically follows a
sequential course.
• However, it is important to note that in some cases symptoms may be prolonged.
Scale
(8-19%)
(Hallmark of concussion)
PREHOSPITAL MANAGEMNT
As per BTF(Brain trauma foundation)
MANAGEMENT IN ED /TRIAGE
Primary Survey
• Airway
– Clear and maintain airway
• Breathing
– Supply oxygen (target PaCO2 30-35 mmHg)
– Look for and treat injuries
• Circulation
– P/BP/Neck veins/external haemorrhage
– Temperature /capillary refill
• Disability
– Assess GCS
• The GCS score that has the most prognostic importance is referred to as the
postresuscitation GCS, obtained after the patient's airway and hemodynamic status have
been stabilized.
– Pupillary size and response
– Other brainstem reflexes: Corneal /Cough /gag reflex
– Signs of Spinal cord injury and Other lateralizing signs of injury
• Exposure
– After adequate collar immobilization of neck and log roll for back examination
– For Adequate complete examination
– Prevention of hypothermia
Secondary Survey
• History:
– Allergy
– Medication
– Past medical history (Including pregnancy)
– Last meal
– Events relating to injury
• Examination:
– Head
– Eyes
– Face
– Neck
– Chest
– Abdomen
– Pelvis
– Extremities
• Detailed Neurological reassessment:
– GCS/Pupils /Motor /Sensory
• Adjuvant Test
– CT Scan (“MAN SCAN”—tomogram from head to knee)
Requirement of Imaging
• ATLS guidelines :
– a goal of 30 minutes between initial assessment and CT
scan.
• The Canadian CT Head Rule is useful for indication of
CT scan: includes the following high-risk factors and
two additional medium-risk factors
• Other Imaging:
– MRI BRAIN
– CT ANGIOGRAPHY OF CEREBRAL VESSELS
CLASSIFY THE SEVERITY
• ONCE
– INITIAL ASSESSMENT AND
– RESUSCITATION
– IMAGING
THEN
Classify as per GCS scoring and management of
1. GCS score of 3 to 12 -- (moderate and severe TBI) and an abnormal CT
scan will require :
– Neurotrauma intensive care unit specialized care.
2. GCS scores of 13 to 15 (mild TBI) depends on the :
– degree of injury and
– the cause of the depressed GCS score (e.g., alcohol, illicit drugs, hypoxia).
MILD TBI
• commonly associated with transient
confusion, temporary loss of consciousness,
and amnesia without significantly poor GCS
scores.
• GCS: 13-15
• Watch for “Talk and Die” patient (ask for lucid
interval)
• WHO definition : Concussion and Mild TBI
• CDC guidelines
CDC Guidelines for Mild TBI
1. Any period of observed or self-reported transient
confusion, disorientation, or impaired
consciousness
2. Any period of observed or self-reported
dysfunction of memory (amnesia) around the time
of injury
3. Observed signs of neurological or
neuropsychological dysfunction
Neuropsychology testing
• ImPACT (Immedicate Post concussion
Assessment and cognitive testing) program
– measures verbal and
– visual memory,
– information processing time, and
– reaction time
• Other Computerized test
– (CogSport, and Headminders)
Post Imaging
• Patients with mild TBI and negative head CT scans :
– Can be safely discharged
– except those on anticoagulant or antiplatelet therapy or
– who have undergone prior neurosurgical procedures.
• Patients with head CT scans showing small contusions
and hemorrhages, but with GCS scores of14 or 15,
– inpatient observation for 24 to 48 hours with frequent
neurological examinations in a monitored setting (e.g.,
every 2 to 4 hours) and
– repeat imaging
Adjunct testing
• fMRI
• PET
• MR Spectroscopy-- (NAA : Cr) Ratio
• DTI
• HD Fibre tracking
• Serum markers:
– S100B Calcium binding protein
– GFAP
– By immuno assay:
• NSE
• MBP
• Tau Protein
• Neuropsychhologic assessment
• Post concussion SCAT 3
Concussion Management
• COGNITIVE
• PHYSICAL REST FOR first 48 hours
• Stepwise approach:
– period of no activity,
– followed by light aerobic exercise,
– sport-specific exercise,
– noncontact training drills,
– full-contact practice, and
– finally return to play/ Full activity
• with a period of 24 hours at each level
• In the event that postconcussion symptoms occur at any step:
– another 24-hour period of rest is completed, and the
– Patient /athelete drops back to the previous step in the program.
• Because of evidence that RTP(return to play) on the day of injury may be
associated with prolonged neuropsychological deficits with delayed onset,
same-day RTP should never be permitted.
Pharmacological treatment
– Not used for TBI deficit
– but useful for patients with postconcussion syndrome
or prolonged postconcussion syndrome
– during the recovery phase
• It is best to avoid medications
– that lower the seizure threshold or
– that cause confusion or contribute to cognitive
slowing, fatigue, or daytime drowsiness
In patient management
• strict monitoring
– GCS
– Vital
– Pupils
– Newer neurological defcit
• Cerebral protection
• Other systemic injuries to be ruled out and
managed accordingly
Drugs
• Symptoms specific management :which are grouped into four
categories
– somatic complaints,
• Headache :
– Acetaminophen
– Amitryptiline
– Limited: DHE / Calcium channel blockers/Anticonvulsant : valproate
,Gabapentin,Topiramate/Beta blockers
– sleep disturbance
• Trazodone (serotonin antagonist )
• Zolpidem
• Prazosin
• Melatonin
– Emotional (TBI associated depression)
• SSRI
– Cognitive
• Amantadine
Post Head injury disease (Post
concussion)
• Post concussion syndrome (6weeks – 3 months)
– ICD 10 Diagnosis of PCS:
• requires the presence of three or more of the following symptoms:
– headache,
– dizziness,
– fatigue,
– irritability,
– insomnia,
– concentration difficulty, and
– Memory difficulty.
• Prolonged post concussion syndrome (>3 months)
• Mild cognitive deficit
• Chronic traumatic encephalopathy
NICE GUIDELINE
Approach to patients with minor head injury-Dr Sameep Koshti (Consultant Neurosurgeon)
Approach to patients with minor head injury-Dr Sameep Koshti (Consultant Neurosurgeon)
Approach to patients with minor head injury-Dr Sameep Koshti (Consultant Neurosurgeon)

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Approach to patients with minor head injury-Dr Sameep Koshti (Consultant Neurosurgeon)

  • 1. APPROACH TO PATIENTS WITH MINOR HEAD INJURY Dr SAMEEP KOSHTI
  • 2. MILD TRAUMATIC BRAIN INJURY (M-TBI) • Definition • Scales • Signs and symptoms • Prehospital management of traumatic brain injury • Management in ED/Triage • Requirement of Imaging :?: • Admission or safe discharge? • Treatment • Sequelae • Post injury Neuropsychology and rehabilitation
  • 3. WHO DEFINITION • Mild TBI is an acute brain injury resulting from mechanical energy to the head from external physical forces. • Operational criteria for clinical identification include: – (i) 1 or more of the following: • confusion or disorientation, • loss of consciousness for 30 minutes or less, • post-traumatic amnesia for less than 24 hours, and/or • Other transient neurological abnormalities such as focal signs, seizure, and intracranial lesion not requiring surgery; – (ii) Glasgow Coma Scale score of 13-15 after 30 minutes post-injury or later upon presentation for health care.
  • 4. Contd.. • These manifestations of MTBI must not be due to : – drugs, alcohol, medications, – caused by other injuries or treatment for other injuries (e.g. systemic injuries, facial injuries or intubation), – caused by other problems (e.g. psychological trauma, language barrier or coexisting medical conditions) or – caused by penetrating craniocerebral injury.
  • 5. Concussion definition • A complex pathophysiological process affecting the brain, induced by biomechanical forces. • Several common features that incorporate clinical, pathologic and biomechanical injury constructs that may be utilized in defining the nature of a concussive head injury include: • 1. Concussion may be caused either by a direct blow to the head, face, neck or elsewhere on the body with an “impulsive” force transmitted to the head. • 2. Concussion typically results in the rapid onset of short-lived impairment of neurological function that resolves spontaneously. However, in some cases, symptoms and signs may evolve over a number of minutes to hours. • 3. Concussion may result in neuropathological changes, but the acute clinical symptoms largely reflect a functional disturbance rather than a structural injury and, as such, no abnormality is seen on standard structural neuroimaging studies. • 4. Concussion results in a graded set of clinical symptoms that may or may not involve loss of consciousness. Resolution of the clinical and cognitive symptoms typically follows a sequential course. • However, it is important to note that in some cases symptoms may be prolonged.
  • 8.
  • 9.
  • 11. As per BTF(Brain trauma foundation)
  • 12.
  • 13.
  • 14. MANAGEMENT IN ED /TRIAGE
  • 15. Primary Survey • Airway – Clear and maintain airway • Breathing – Supply oxygen (target PaCO2 30-35 mmHg) – Look for and treat injuries • Circulation – P/BP/Neck veins/external haemorrhage – Temperature /capillary refill • Disability – Assess GCS • The GCS score that has the most prognostic importance is referred to as the postresuscitation GCS, obtained after the patient's airway and hemodynamic status have been stabilized. – Pupillary size and response – Other brainstem reflexes: Corneal /Cough /gag reflex – Signs of Spinal cord injury and Other lateralizing signs of injury • Exposure – After adequate collar immobilization of neck and log roll for back examination – For Adequate complete examination – Prevention of hypothermia
  • 16. Secondary Survey • History: – Allergy – Medication – Past medical history (Including pregnancy) – Last meal – Events relating to injury • Examination: – Head – Eyes – Face – Neck – Chest – Abdomen – Pelvis – Extremities • Detailed Neurological reassessment: – GCS/Pupils /Motor /Sensory • Adjuvant Test – CT Scan (“MAN SCAN”—tomogram from head to knee)
  • 17. Requirement of Imaging • ATLS guidelines : – a goal of 30 minutes between initial assessment and CT scan. • The Canadian CT Head Rule is useful for indication of CT scan: includes the following high-risk factors and two additional medium-risk factors • Other Imaging: – MRI BRAIN – CT ANGIOGRAPHY OF CEREBRAL VESSELS
  • 18.
  • 19.
  • 20. CLASSIFY THE SEVERITY • ONCE – INITIAL ASSESSMENT AND – RESUSCITATION – IMAGING THEN Classify as per GCS scoring and management of 1. GCS score of 3 to 12 -- (moderate and severe TBI) and an abnormal CT scan will require : – Neurotrauma intensive care unit specialized care. 2. GCS scores of 13 to 15 (mild TBI) depends on the : – degree of injury and – the cause of the depressed GCS score (e.g., alcohol, illicit drugs, hypoxia).
  • 21. MILD TBI • commonly associated with transient confusion, temporary loss of consciousness, and amnesia without significantly poor GCS scores. • GCS: 13-15 • Watch for “Talk and Die” patient (ask for lucid interval) • WHO definition : Concussion and Mild TBI • CDC guidelines
  • 22. CDC Guidelines for Mild TBI 1. Any period of observed or self-reported transient confusion, disorientation, or impaired consciousness 2. Any period of observed or self-reported dysfunction of memory (amnesia) around the time of injury 3. Observed signs of neurological or neuropsychological dysfunction
  • 23. Neuropsychology testing • ImPACT (Immedicate Post concussion Assessment and cognitive testing) program – measures verbal and – visual memory, – information processing time, and – reaction time • Other Computerized test – (CogSport, and Headminders)
  • 24. Post Imaging • Patients with mild TBI and negative head CT scans : – Can be safely discharged – except those on anticoagulant or antiplatelet therapy or – who have undergone prior neurosurgical procedures. • Patients with head CT scans showing small contusions and hemorrhages, but with GCS scores of14 or 15, – inpatient observation for 24 to 48 hours with frequent neurological examinations in a monitored setting (e.g., every 2 to 4 hours) and – repeat imaging
  • 25. Adjunct testing • fMRI • PET • MR Spectroscopy-- (NAA : Cr) Ratio • DTI • HD Fibre tracking • Serum markers: – S100B Calcium binding protein – GFAP – By immuno assay: • NSE • MBP • Tau Protein • Neuropsychhologic assessment • Post concussion SCAT 3
  • 26. Concussion Management • COGNITIVE • PHYSICAL REST FOR first 48 hours • Stepwise approach: – period of no activity, – followed by light aerobic exercise, – sport-specific exercise, – noncontact training drills, – full-contact practice, and – finally return to play/ Full activity • with a period of 24 hours at each level • In the event that postconcussion symptoms occur at any step: – another 24-hour period of rest is completed, and the – Patient /athelete drops back to the previous step in the program. • Because of evidence that RTP(return to play) on the day of injury may be associated with prolonged neuropsychological deficits with delayed onset, same-day RTP should never be permitted.
  • 27. Pharmacological treatment – Not used for TBI deficit – but useful for patients with postconcussion syndrome or prolonged postconcussion syndrome – during the recovery phase • It is best to avoid medications – that lower the seizure threshold or – that cause confusion or contribute to cognitive slowing, fatigue, or daytime drowsiness
  • 28. In patient management • strict monitoring – GCS – Vital – Pupils – Newer neurological defcit • Cerebral protection • Other systemic injuries to be ruled out and managed accordingly
  • 29. Drugs • Symptoms specific management :which are grouped into four categories – somatic complaints, • Headache : – Acetaminophen – Amitryptiline – Limited: DHE / Calcium channel blockers/Anticonvulsant : valproate ,Gabapentin,Topiramate/Beta blockers – sleep disturbance • Trazodone (serotonin antagonist ) • Zolpidem • Prazosin • Melatonin – Emotional (TBI associated depression) • SSRI – Cognitive • Amantadine
  • 30. Post Head injury disease (Post concussion) • Post concussion syndrome (6weeks – 3 months) – ICD 10 Diagnosis of PCS: • requires the presence of three or more of the following symptoms: – headache, – dizziness, – fatigue, – irritability, – insomnia, – concentration difficulty, and – Memory difficulty. • Prolonged post concussion syndrome (>3 months) • Mild cognitive deficit • Chronic traumatic encephalopathy