One strategy in the battle against cancer involves harnessing the potential of the antioxidant vitamin C. This versatile compound has shown promise in augmenting immunotherapy and regulating epigenetic processes.

1. APPLICATIONS
OF HIGH-DOSE
VITAMIN C IN
TREATING
CANCER

2. One strategy in the battle against cancer
involves harnessing the potential of the
antioxidant vitamin C. This versatile compound
has shown promise in augmenting
immunotherapy and regulating epigenetic
processes. Research into the therapeutic
benefits of high-dose vitamin C consumption
dates back to the 1970s and has included a
study involving 100 terminal cancer patients.

3. With a high-dose vitamin C regimen, there were 10 percent survival rates
compared to no survivals in malignancy cases that underwent conventional
treatment. Subsequently, Japanese patients with uterine cancer who
received high-dose vitamin C (up to 30g) daily lived six times as long as
those receiving only 4 grams daily.
More recent findings show that high-dose vitamin C consumption is linked
with decreased risk of stomach, oral cavity, esophagus, breast, cervix, and
rectum cancers. In addition, it reduces risks associated with cancers of
non-hormonal origins.

4. The chemical makeup of vitamin C (C6H8O6)-ascorbate or/and
ascorbic acid is essential in understanding its effects on the
human body. As a water-soluble nutrient, vitamin C is produced
by mammals such as mice but not humans. For this reason,
people must obtain vitamin C through dietary intake.
A powerful antioxidant, vitamin C assists in ensuring the proper
functioning of vital tissue structures and protects
macromolecules such as fats, proteins, and DNA from oxidation.
Also an enzyme co-factor, vitamin C co-activates several
biosynthetic enzymes that enable the body to produce metabolic
energy and hormones. It also has a role in controlling gene
transcription and can epigenetically modify enzymes.

5. Health risks such as bleeding gums, anemia, infection, delayed wound
healing, and scurvy are elevated without sufficient vitamin C. Vitamin C is
also used for treating diabetes, cataracts, strokes, and atherosclerosis.
Unlike fat-soluble vitamins, vitamin C can be tolerated in high doses without
toxicity.
High-dose vitamin C promotes oxidation in cases where it circulates in
extremely high concentrations within the blood that is also highly
oxygenated. Catalase, an enzyme abundant in the blood and normal
tissues, is less common in malignant tumors. The catalase immediately
neutralizes oxidation when healthy cells tolerate high vitamin C dosages.

6. Because tumorous cells tend to lack catalase, vitamin C’s
oxidative capacity to eliminate malignant cells is boosted.
Cancer cells produce very little catalase because their
preferred environment is one of mild oxidative stress, which
encourages the rapid growth of tumorous cells. High-dose
vitamin C infusions produce large quantities of hydrogen
peroxide, which catalase usually counteracts.
Unlike conventional therapy approaches such as
chemotherapy, radiation, and surgery, high-dose intravenous
vitamin C is selectively toxic. Only cancerous cells are
impacted, with very little damage occurring in healthy cells.
Experimental investigations in recent years have
demonstrated growth arrest among tumor cells exposed to
high-dose vitamin C. Its functions include inhibiting metastasis
and inflammatory-associated cytokine production while
boosting tumor inclusion and the effects of traditional
chemotherapy.

7. The intravenous delivery method is preferred
because it offers a highly concentrated form of
vitamin C. When administered intravenously,
vitamin C levels can surge over 70 times higher
compared to oral delivery. This heightened
concentration allows for the maximization of
oxidative stress in cancer cells, which are more
susceptible to these effects than normal cells.