This document discusses the history and development of antenatal care (ANC) models. It outlines the traditional ANC model which involved frequent visits and classifying women as high or low risk. Issues with this model led to the focused ANC model promoted by WHO, which recommends 4 visits and focuses on essential services. The 2016 WHO ANC guideline further refined this, recommending a minimum of 8 contacts to provide integrated care throughout pregnancy. The document details the recommended components, timing and interventions for each contact to promote positive pregnancy outcomes.
This ppt may help in understanding Rh negative women during pregnancy, labour and postpartum. Great advancements have been made in the detection and management of this condition, and many of our Rh-negative women can now have a happy obstetric career.
This presentation describes approach to a patient presenting with early pregnancy bleeding. It also includes a brief outline about the management of miscarriage, molar pregnancy and ectopic pregnancy.
A comprehensive overview of hypertensive disorders in pregnancy with its complications and management. Mainly focused on gestational hypertension, preeclampsia and eclampsia.
This ppt may help in understanding Rh negative women during pregnancy, labour and postpartum. Great advancements have been made in the detection and management of this condition, and many of our Rh-negative women can now have a happy obstetric career.
This presentation describes approach to a patient presenting with early pregnancy bleeding. It also includes a brief outline about the management of miscarriage, molar pregnancy and ectopic pregnancy.
A comprehensive overview of hypertensive disorders in pregnancy with its complications and management. Mainly focused on gestational hypertension, preeclampsia and eclampsia.
Preeclampsia is a disorder that is unique to human pregnancy, and the only known cure for this complication is delivery. Preeclampsia affects approximately 4% to 5% of pregnancies . The Preeclampsia Foundation states that: “Globally, preeclampsia and other hypertensive disorders of pregnancy are a leading cause of maternal and infant illness and death. By conservative estimates, these disorders are responsible for 76,000 maternal and 500,000 infant deaths each year.” As is evident from the statement that, preeclampsia is a major contributor to maternal and fetal morbidity and mortality worldwide. In India, the incidence of preeclampsia is reported to be 8-10% among the pregnant women. According to a study, the prevalence of hypertensive disorders of pregnancy was 7.8% with preeclampsia in 5.4% of the study population in India
Preeclampsia is a disorder that is unique to human pregnancy, and the only known cure for this complication is delivery. Preeclampsia affects approximately 4% to 5% of pregnancies . The Preeclampsia Foundation states that: “Globally, preeclampsia and other hypertensive disorders of pregnancy are a leading cause of maternal and infant illness and death. By conservative estimates, these disorders are responsible for 76,000 maternal and 500,000 infant deaths each year.” As is evident from the statement that, preeclampsia is a major contributor to maternal and fetal morbidity and mortality worldwide. In India, the incidence of preeclampsia is reported to be 8-10% among the pregnant women. According to a study, the prevalence of hypertensive disorders of pregnancy was 7.8% with preeclampsia in 5.4% of the study population in India
Antenatal care which is just the care given to a pregnant woman through out pregnancy from the time of conception until the time the woman goes into labor.
I am a student who graduated with bachelor of science in midwifery from Lira University and a master degree in microbiology from Kampala International University
The primary aim of preconception and interconception care is to improve maternal health and birth outcome for mother, infant and family through prevention and interventions.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
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disorder called alcohol use disorder (AUD), with mild, moderate,
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The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
3. INTRODUCTION
ANC is a care given to pregnant women with the
aim of improving the maternal and perinatal out
come.
Components of ANC:-
Evaluation of health status of the mother
and fetus
Identification of mothers at risk of
complications
Anticipation and prevention of problems
Patient education and communication.
Health promotion
Risk assessment
Care provision.
4. It decreases perenatal & maternal mortality with better
pregnancy out come .
ANC has been effective in the treatment of;
Anemia
Hypertension
STDs
5. Cont...
History
1901 - Mrs William Lowel putnam of Boston
started nurse visits to home
1911 - out patient ANC clinic
1920 - Edinburgh Dame Janet Campbell, started
national system of ANC
1970 - Risk assessment approach introduced,
Focused ANC approach
2016 WHO ANC Model
6. Cont...
Historically the practice of a comprehensive and
organized delivery of antenatal care passed
through three phases:
1. Traditional ANC model
2. Focused ANC model
3. ANC for positive pregnancy experience
7. Traditional ANC model
Developed in the early 1990s
Frequent visit
Classifying pregnant women into low and high
risk by predicting the complication
Visit pattern
Every 4 weeks till 28 weeks
Every 2 weeks from 28-36 weeks
Every week from 36 weeks till delivery
Total number of visits 12-14
8. Basic Problems in Traditional
Approach
The model resulted in insignificant gains
It was not applicable in the low resource context
Assumes that more frequent ANC visit is better
Quantity of care is emphasized rather than the essential
elements of care
It has developed/changed very little despite increasing
medical knowledge
9. Why the Risk Assessment Approach
has Not Worked
Top five causes of maternal death:
Hemorrhage – difficult to predict
Obstructed labor – difficult to predict
PIH - no way to predict
Puerperal sepsis
Complications of unsafe abortion
10. Focused ANC
Focused four ANC visit by skilled provider
Birth preparedness & complications readiness
planning with family
Detection & management of coexisting condition
HIV test
Counseling on BF, FP, Danger signs, STI, Nutrition.
Treatment of diagnosed infection
11. Behavioral Change Messages &
Advocacy
Every pregnancy is at risk.
Pregnant women need four ANC visits
If you have problem don't wait for next visits
Practices are based on scientific evidences.
Best practices save recourses, save lives
12. Cont...
FOCUSED ANC Recognizes Three Key Realities:
1. ANC visits are unique opportunity for early
diagnosis & treatment of problems in the mother
& newborns
2. Majority of pregnancies progress without
complications
3. All women are considered at risk of complications
because most complications cannot be predicted by
any type of risk categorization.
Therefore, all woman should receive essential
care & monitoring for complications that are
focused on individual needs.
13. Objectives of Focused ANC
The major goal of ANC is to help women maintain
normal pregnancies through:
1. Health promotion and disease prevention
2. Early detection and treatment of complications and
existing diseases
3. Birth preparedness and complication readiness
planning
14. CONT
Health Promotion and Disease Prevention:
Immunization against tetanus
Iron and folate supplementation
How to recognize danger signs, what to do, and where to
get help
Voluntary counseling and testing for HIV
The benefit of skilled attendance at birth
Breastfeeding
Establish access to family planning
15. CONT
Protection against malaria with insecticide-treated bed
nets
Good nutrition and the importance of rest
Protection against iodine deficiency
Risks of using tobacco, alcohol, local stimulants, and
traditional remedies
Hygiene and infection prevention practices
Defibulation – for women with type-III female genital
cutting
16. CONT
Birth Preparedness and Complication Readiness:
Approximately 15% of women will develop a life-
threatening complication.
Every woman and her family should have a plan for:
A skilled attendant at birth
The place of birth and how to get there including how to access
emergency transportation if needed
Items needed for the birth
Money saved to pay for transportation, the skilled provider and
for any needed medications and supplies that may not been
provided for free
Support during and after the birth (e.g., family, friends)
Potential blood donors in case of emergency
17. Principles of Focused ANC
The model should include simple format
Identification of women with special health conditions
or risk factors should be done very carefully
Health care providers should make all pregnant women
feel welcome at their clinic
Only examinations & tests that serve an immediate
purpose that have been proven to be beneficial should
be performed.
Whenever possible rapid & easy to perform test should
be used; and treatment should be initiated at the clinic
the same day.
18. Overview of Focused ANC
Segregate pregnant women in to two groups
Those eligible to receive basic ANC component - 75%
Those who need special care - 25%
This classification based on the risk scoring form used
at first visit to the clinic.
19. CONT
The activities in the basic component fall within 3
general areas.
1. Screening for health & socio-economic conditions.
2. Providing therapeutic interventions.
3. Educating pregnant women.
These activities are distributed over four visits.
20. Basic Component Focused ANC
The first visit
Should occur in the first trimester (ideally before 12
wks but no later than 16wks)
Expected to take 30-40 minutes.
Emphasis on medical & obstetric history.
Physical & Bio-Chemical examinations are few &
less resource demanding.
Only one routine Vaginal Examination is
recommended
Routine iron supplementation.
Individual interaction, general information about
pregnancy & delivery, related complications
21. CONT
Content of first visit
1.History –personal ,medical, obstetric history
2.Physical examination
3.Tests : Hgb, BG & RH, U/A, VDRL/RPR, HIV, Stool Ex
4.Interventions Iron & Folate to all women 60mg
elemental iron and 400microgram folate per day if the
side effect un tolerable 120mg and 2800microgram (Fe
and Folate weekly ) , TT1, referral accordingly .Ca, I2,
and VitA supplementation where shortage
5.Advice, questions, scheduling
6.Complete record.
22. CONT
The second visit
At 24 to 28 weeks
expected to take 20 minutes
Contents
1. History review
2. Physical examination
3. Tests-
U/A, Hgb if the previously anemic
GTD-OGTT
first trimester in women with significant risk factors (eg, body
mass
index >30 kg/m 2 , gestational diabetes or baby >4500 g in a
prior
pregnancy, family history of diabetes in a first degree relative
4.Assess for referral
5.Interventions-iron-
23. CONT
The Third visit
Should take place at around 32 weeks(30-32)
Expected to take 20minutes
Contents
1.History
2.Physical examination
3.Tests- U/A, Hemoglobin test for all women,
CDC recommends testing for sexually transmitted diseases (STDs, eg,
HIV, syphilis, hepatitis B surface antigen, Chlamydia, gonorrhea) in the
third trimester (28 to 36 weeks) in women who
Were diagnosed with a STD earlier in pregnancy
Continue to have risk factors for acquiring a STD
Acquired a new risk factor during pregnancy (eg, a new or more than
one sex partner, evaluation or treatment for a STD, injection of
nonprescription drugs)
24. CONT
4.Group B beta-hemolytic streptococcus testing all women
at 35-37 weeks gestation
5.Ultrasound examination (Fetal Presentation , ESFW, in
risk mother IUGR,BPP)
6.Interventions-iron, TT2.
7.Advice –ensure availability of transports
8.Maintain records & appointment
25. CONT
The fourth visit
Should be the final visit
Between 36 - 38 weeks. Or 37-41
Breech should be discovered.
Content
1. Review history
2. Physical examination
3. Test-U/A
4. Interventions-iron
5. Advice - Post partum visit, BF, Contraception,
Delivery plan, Danger sign
26. 2016 WHO ANC MODEL
Through timely and appropriate evidence-based
actions related to :
health promotion, disease prevention, screening, and
treatment
Reduces complications from pregnancy and childbirth
Reduces stillbirths and perinatal deaths
Integrated care delivery throughout pregnancy
27. Cont...
The guideline uses the term ‘contact’ - it implies an active
connection between a pregnant woman and a health care
provider that is not implicit with the word ‘visit’.
quality care including medical care, support and timely and relevant
information
In terms of the operationalization of this recommendation,
‘contact’ can take place at the facility or at community level
be adapted to local context through health facilities or community
outreach services
‘Contact’ helps to facilitate context-specific recommendations
Interventions (such as malaria, tuberculosis)
Health system (such as task shifting)
28. Cont...
A healthy pregnancy for mother and baby (including
preventing or treating risks, illness and death)
Physical and sociocultural normality during pregnancy
Effective transition to positive labour and birth
Positive motherhood (including maternal self-esteem,
competence and autonomy)
29. CONT
WHO recommends a minimum of eight contacts:
Five contacts in the third trimester,
One contact in the first trimester, and
Two contacts in the second trimester.
The core package of ANC services and consensus on
what care is provided at each contact, who provides
ANC care (which health cadre), where care is
provided (which system level), and how care is
provided (platforms) and coordinated across all eight
ANC contacts.
30. Cont...
2016 WHO ANC model
First trimester
Contact 1: up to 12 weeks
Second trimester
Contact 2: 20 weeks
Contact 3: 26 weeks
Third trimester
Contact 4: 30 weeks
Contact 5: 34 weeks
Contact 6: 36 weeks
Contact 7: 38 weeks
Contact 8: 40 weeks
Return for delivery at 41 weeks if not given birth.
Note: Intermittent preventive treatment of malaria in pregnancy should be started at ≥ 13 weeks
31. What shall we do at each
contact?
Week of
gestation
Intervention
Upto -12
weeks
• Baseline:
History (Medical, Pyschological,Genetic history)
Reproductive history(previous deliveries, abortion,mode
of deliveries)
Previous obstetrics complications
• Physical examination
General
Blood pressure
Weight
Pelvic examination and pelvimetry
Breast examination
Fundal height
Fetal position and heart rate
Cervical examination
Pregnancy test
32. cont
• Laboratory
Hgb/hct
Pap smear
Antibody screen
Blood and RH factor
UA
Urine culture
Rubella titer
Gonoccocal culture
HBV
HIV
Toxoplasmosis
Genetic screen
Illicit drug use
Nuchal translucency
Serum marker screening for aneuploidy
33. 16-20
weeks
26-28
weeks
• Update medical and psychosocial
• Physical examination
General
Blood pressure
Weight
Fundal height
Fetal position and heart beat
AFP if indicate
Multiple marker screening if indicate
Anatomic scan upto 22wks
Update medical and pschosocial
Glucose tolerance test if indicate
Hgb/hct
34. Cont...
30 weeks
34weeks
• Update medical and psychosocial
• Physical examination
General
Blood pressure
Weight
Fundal height
Fetal position and heart beat
Child birth education
Risk assessment
• Update medical and psychosocial
• Physical examination
General
Blood pressure
Weight
Fundal height
Fetal position and heart beat
Child birth education
Risk assessment
35. cont
36 weeks
38 weeks
• Update medical and psychosocial
• Physical examination
General
Blood pressure
Weight
Fundal height
Fetal position and heart beat
HBV
HIV
Hgb/hct
Gbs growth
• Update medical and psychosocial
• Physical examination
General
Blood pressure
Weight
Fundal height
Fetal position and heart beat
36. cont
40 weeks • Update medical and psychosocial
• Physical examination
General
Blood pressure
Weight
Fundal height
Fetal position and heart beat
Risk assessment
• Return for delivery at 41 weeks if not given birth.
• Update medical and psychosocial
• Assess risk and BPP 2x/week
• Admit at 41wks +6days
37. Early ultrasound
In the new WHO ANC guideline, an ultrasound scan before 24
weeks’ gestation is recommended for all pregnant women to:
Estimate gestational age
Detect fetal anomalies and multiple pregnancies
Enhance the maternal pregnancy experience
An ultrasound scan after 24 weeks’ gestation (late ultrasound) is
not recommended for pregnant women who have had an early
ultrasound scan.
Stakeholders should consider offering a late ultrasound scan to
pregnant women who have not had an early ultrasound scan.
Ultrasound equipment can also used for other indications (e.g.
obstetric emergencies) or by other medical departments
38. Recommendations on ANC
49 recommendations were grouped into five topic
areas:
A. Nutritional interventions (14)
B. Maternal and fetal assessment (13)
C. Preventive measures (7)
D. Interventions for common physiological symptoms
(6)
E. Health systems interventions to improve the
utilization and quality of ANC (9)
39. Nutritional intervention
A.1.1: Counselling about healthy eating and
keeping physically active during pregnancy is
recommended for pregnant women to stay healthy and
to prevent excessive weight gain during pregnancy.
Recommended
A.1.2: In undernourished populations, nutrition
education on increasing daily energy and protein
intake is recommended for pregnant women to reduce
the risk of low-birth-weight neonates.
Context-specific
recommendation
A.1.3: In undernourished populations, balanced
energy and protein dietary supplementation is
recommended for pregnant women to reduce the risk
of stillbirths and small-for-gestational-age neonates.
Context-specific
recommendation
A.1.4: In undernourished populations, high-protein
supplementation is not recommended for pregnant
women to improve maternal and perinatal outcomes.
Not
recommended
40. Cont...
A.2.1: Daily oral iron and folic acid supplementation
with 30 mg to 60 mg of elemental iron and 400 µg
(0.4 mg) of folic acid is recommended for pregnant
women to prevent maternal anaemia, puerperal sepsis,
low birth weight, and preterm birth.
Recommende
d
A.2.2: Intermittent oral iron and folic acid
supplementation with 120 mg of elemental iron and
2800 µg (2.8 mg) of folic acid once weekly is
recommended for pregnant women to improve maternal
and neonatal outcomes if daily iron is not acceptable due
to side-effects, and in populations with an anaemia
prevalence among pregnant women of less than 20%.
Context-
specific
recommendati
on
A.3: In populations with low dietary calcium intake, daily
calcium supplementation (1.5–2.0 g oral elemental
calcium) is recommended for pregnant women to reduce
the risk of pre-eclampsia.
Context-
specific
recommendati
on
A.4: Vitamin A supplementation is only recommended
for pregnant women in areas where vitamin A deficiency
is a severe public health problem, to prevent night
blindness.
Context-
specific
recommendati
on
41. Cont...
A.5: Zinc supplementation for pregnant women is only
recommended in the context of rigorous research.
Context-
specific
recommendati
on (research)
A.6: Multiple micronutrient supplementation is not
recommended for pregnant women to improve maternal
and perinatal outcomes.
Not
recommended
A.7: Vitamin B6 (pyridoxine) supplementation is not
recommended for pregnant women to improve maternal
and perinatal outcomes.
Not
recommended
A.8: Vitamin E and C supplementation is not
recommended for pregnant women to improve maternal
and perinatal outcomes.
Not
recommended
A.9: Vitamin D supplementation is not recommended
for pregnant women to improve maternal and perinatal
outcomes.
Not
recommended
A.10: For pregnant women with high daily caffeine intake
(more than 300 mg per day), lowering daily caffeine
intake during pregnancy is recommended to reduce the
Context-
specific
recommendati
42. B.1. Maternal assessment - 1
B.1.1: Full blood count testing is the recommended
method for diagnosing anaemia in pregnancy. In
settings where full blood count testing is not available,
on-site haemoglobin testing with a haemoglobinometer is
recommended over the use of the haemoglobin colour
scale as the method for diagnosing anaemia in
pregnancy.
Context-
specific
recommendati
on
B.1.2: Midstream urine culture is the recommended
method for diagnosing asymptomatic bacteriuria
(ASB) in pregnancy. In settings where urine culture is not
available, on-site midstream urine Gram-staining is
recommended over the use of dipstick tests as the
method for diagnosing ASB in pregnancy.
Context-
specific
recommendati
on
B.1.3: Clinical enquiry about the possibility of
intimate partner violence (IPV) should be strongly
considered at antenatal care visits when assessing
conditions that may be caused or complicated by IPV in
order to improve clinical diagnosis and subsequent care,
where there is the capacity to provide a supportive
Context-
specific
recommendati
on
43. Cont...
B.1.4: Hyperglycaemia first detected at any time during
pregnancy should be classified as either gestational diabetes
mellitus (GDM) or diabetes mellitus in pregnancy, according to
WHO criteria.
Recom
mende
d
B.1.5: Health-care providers should ask all pregnant women
about their tobacco use (past and present) and exposure to
second-hand smoke as early as possible in the pregnancy and at
every antenatal care visit.
Recom
mende
d
B.1.6: Health-care providers should ask all pregnant women
about their use of alcohol and other substances (past and
present) as early as possible in the pregnancy and at every
antenatal care visit.
Recom
mende
d
B.1.7: In high-prevalence settings, provider-initiated testing and
counselling (PITC) for HIV should be considered a routine
component of the package of care for pregnant women in all
antenatal care settings. In low-prevalence settings, PITC can be
considered for pregnant women in antenatal care settings as a
key component of the effort to eliminate mother-to-child
transmission of HIV, and to integrate HIV testing with syphilis,
viral or other key tests, as relevant to the setting, and to
strengthen the underlying maternal and child health systems.
Recom
mende
d
B.1.8: In settings where the tuberculosis (TB) prevalence in the
general population is 100/100 000 population or higher,
Contex
t-
44. B.2.Fetal assessment
B.2.1: Daily fetal movement counting, such as with “count-to-ten” kick
charts, is only recommended in the context of rigorous research.
Context-
specific
recommendat
ion (research)
B.2.2: Replacing abdominal palpation with symphysis-fundal height
(SFH) measurement for the assessment of fetal growth is not
recommended to improve perinatal outcomes. A change from what is
usually practiced (abdominal palpation or SFH measurement) in a
particular setting is not recommended.
Context-
specific
recommendat
ion
B.2.3: Routine antenatal cardiotocography is not recommended for
pregnant women to improve maternal and perinatal outcomes.
Not
recommende
d
B.2.4: One ultrasound scan before 24 weeks of gestation (early
ultrasound) is recommended for pregnant women to estimate
gestational age, improve detection of fetal anomalies and multiple
pregnancies, reduce induction of labour for post-term pregnancy, and
improve a woman’s pregnancy experience.
Recommende
d
45. C. Preventive measures
C.1: A seven-day antibiotic regimen is recommended for all pregnant
women with asymptomatic bacteriuria (ASB) to prevent persistent
bacteriuria, preterm birth and low birth weight.
Recommend
ed
C.2: Antibiotic prophylaxis is only recommended to prevent recurrent
urinary tract infections in pregnant women in the context of rigorous
research.
Context-
specific
recommend
ation
C.3: Antenatal prophylaxis with anti-D immunoglobulin in non-
sensitized Rh-negative pregnant women at 28 and 34 weeks of
gestation to prevent RhD alloimmunization is only recommended in the
context of rigorous research.
Context-
specific
recommend
ation
C.4: In endemic areas, preventive anthelminthic treatment is
recommended for pregnant women after the first trimester as part of
worm infection reduction programmes.
Context-
specific
recommend
ation
C.5: Tetanus toxoid vaccination is recommended for all pregnant
women, depending on previous tetanus vaccination exposure, to
prevent neonatal mortality from tetanus.
Recommend
ed
46. Cont...
C.6: In malaria-endemic areas in Africa, intermittent
preventive treatment with sulfadoxine-
pyrimethamine (IPTp-SP) is recommended for all
pregnant women. Dosing should start in the second
trimester, and doses should be given at least one month
apart, with the objective of ensuring that at least three
doses are received.
Context-
specific
recommendatio
n
C.7: Oral pre-exposure prophylaxis (PrEP) containing
tenofovir disoproxil fumarate (TDF) should be offered as
an additional prevention choice for pregnant women at
substantial risk of HIV infection as part of combination
prevention approaches.
Context-
specific
recommendatio
n
48. E. Health systems interventions to
improve the utilization and quality of
ANC
E.1: It is recommended that each pregnant woman carries
her own case notes during pregnancy to improve
continuity, quality of care and her pregnancy experience.
Recommend
ed
E.2: Midwife-led continuity-of-care models, in which a
known midwife or small group of known midwives supports
a woman throughout the antenatal, intrapartum and
postnatal continuum, are recommended for pregnant
women in settings with well functioning midwifery
programmes.
Context-
specific
recommenda
tion
E.3: Group antenatal care provided by qualified health-
care professionals may be offered as an alternative to
individual antenatal care for pregnant women in the
context of rigorous research, depending on a woman’s
preferences and provided that the infrastructure and
resources for delivery of group antenatal care are
available.
Context-
specific
recommenda
tion
49. cont
E.4.1: The implementation of community mobilization
through facilitated participatory learning and action
(PLA) cycles with women’s groups is recommended to
improve maternal and newborn health, particularly in rural
settings with low access to health services. Participatory
women’s groups represent an opportunity for women to
discuss their needs during pregnancy, including barriers to
reaching care, and to increase support to pregnant women.
Context-
specific
recommend
ation
E.4.2: Packages of interventions that include household and
community mobilization and antenatal home visits are
recommended to improve antenatal care utilization and
perinatal health outcomes, particularly in rural settings with
low access to health services.
Context-
specific
recommend
ation
50. Cont...
E.5.1: Task shifting the promotion of health-related
behaviours for maternal and newborn health to a broad
range of cadres, including lay health workers, auxiliary
nurses, nurses, midwives and doctors is recommended.
Recomme
nded
E.5.2: Task shifting the distribution of recommended
nutritional supplements and intermittent preventative
treatment in pregnancy (IPTp) for malaria prevention to a
broad range of cadres, including auxiliary nurses, nurses,
midwives and doctors is recommended.
Recomme
nded
E.6: Policy-makers should consider educational, regulatory,
financial, and personal and professional support interventions
to recruit and retain qualified health workers in rural and
remote areas.
Context-
specific
recomme
ndation
51. Cont...
E.7: Antenatal care models with
a minimum of eight contacts
are recommended to reduce
perinatal mortality and improve
women’s experience of care.
Recommend
ed
52. contact recommended to reduce perinatal
mortality and improve women experience
care
Evidence suggesting increased perinatal deaths in 4-visit ANC
model
Evidence supporting improved safety during pregnancy through
increased frequency of maternal and fetal assessment to detect
complications
Evidence supporting improved health system communication
and support around pregnancy for women and families
Evidence indicating that more contact between pregnant women
and respectful, knowledgeable health care workers is more likely
to lead to a positive pregnancy experience
Evidence from HIC studies indicating no important differences in
maternal and perinatal health outcomes between ANC models
that included at least eight contacts and ANC models that
included 11 to 15 contacts.