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125
Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in
Telehealth
Analysis of Economic and Business Factors Influencing
Disruptive Innovation in Telehealth
Análisis de factores económicos y empresariales que influyen la
Innovación Disruptiva en Telesalud
Abstract
Objective. Analysis of economic and business factors influencing disruption innovation in
healthcare taking as a reference Telehealth systems and technologies. Methods. Analysis of
economic and business decision factors that influence the adoption of new technologies are
qualitatively analyzed using as a case example Telehealth systems. Results. Main factors for the
adoption of new technologies in healthcare are identified and analyzed. Factors include new
technology adoption cost, usability, perceived value, competitive systems, old systems competitive
cost and performance, and type of users, between others.
Keywords: Telehealth systems, Technology adoption, Disruptive innovation, Ecosystems.
Resumen
Objetivo: análisis de los factores que influyen en la adopción de nuevas tecnologías en el cuidado
de la salud tomando como referencia la Telesalud o el uso de las tecnologías de la información y la
comunicación en la asistencia sanitaria. Métodos: el análisis de los factores de decisión económica
y empresarial que influyen en la adopción de nuevas tecnologías se analiza cualitativamente
utilizando como ejemplo de caso los sistemas de Telehealth. Resultados: se identifican y analizan
los principales factores para la adopción de nuevas tecnologías en la atención de la salud por
Telesalud. Los factores incluyen costo de adopción de nuevas tecnologías, usabilidad, valor
percibido, sistemas competitivos, costos y desempeño competitivos de los sistemas actuales, y tipo
de usuarios, entre otros.
Palabras clave: telesalud, adopción tecnológica, innovación disruptiva, ecosistemas
Jorge Millan1,2
, PhD; Leonardo1
Yunda, PhD; Andrés Valencia2
1. Bioinnova Group, School of Health – Universidad Nacional Abierta y a Distancia UNAD, Bogotá, Colombia.
2. Sigma Biomedical, Hialeah, Florida – USA.
Correspondencia: jmillan@sigmabiomedical.com - leyunda@ieee.org
Articulo original producto de la investigación
Recibido: 20/03/2017
Aceptado: 01/08/2017
126
NOVA. 2017; 15 (28): 125-136
Introduction
The Colombian healthcare system faces great cha-
llenges and difficulties, and thus, new methods,
models, and tools need to be developed, introdu-
ced and adopted to improve the efficiency, quality
and opportunity of healthcare service provision.
The challenges are mainly related to the resources
committed in the health sector and the efficiency
in their use, which not only affect health status,
but also the welfare and economic growth of the
population. Government health policies and regu-
lations, which define the schemes, systems, com-
ponents and elements of the health system, and
define the modalities of health insurance, finan-
cing of health services, coverage for the poor, and
the management of private and public institutions
in the provision of services, need to begin a pro-
cess of restructuring to prevent a collapse of the
health system in Colombia.
A main issue is how to maximize the wellness of
the population by providing quality and timely
health services using existing resources. Health-
care service provision is reflected in the coverage
and quality of the service provided by public and
private entities, cost effectiveness, as well as bene-
fit and utility. The health service provision must
be studied from a broad sense. The study needs
to analyze current health economics in Colom-
bia and the economic impact of new technolo-
gies such as Telehealth have in the provision of
services. In the panel “Hacia un Plan País en Te-
lesalud” (Towards a Country Plan in Telehealth)
(1), the ministries of Communications and Social
Protection discuss the future of the provision of
health services through Information and Com-
munication Technologies (ICT). The benefits of
a Telehealth system are varied. In addition to ex-
panding the coverage and access of the system to
the poorest, they allow specialized and quality care
to these populations. Telehealth can become an
effective and efficient strategy to reduce costs and
decongest the health system in Colombia, given
that appropriate investment is performed for the
required equipment, infrastructure and changes in
the organizational structure.
Although new information and communication
technologies and applications have emerged in the
last decade in areas such as education, commerce,
business, entertainment, government and healthca-
re, their practical implementation and widespread
adoption and use in healthcare have not happened
rapidly. Multiple factors may influence the deci-
sion of healthcare operators and administrators
on acquiring and implementing new Telehealth
products and technologies. Careful analysis of the
factors influencing adoption is important for both
solution developers and health care providers for
optimal use of their investment. Factors include a)
health economics dynamics, b) effective implemen-
tation of Telehealth technologies as new healthcare
models, and c) the way disruptive innovation in-
fluences widespread use of new technologies. These
main factors are analyzed and discussed in the fo-
llowing sections.
Health Economics
Health economics, as defined by Selma Mushkin
(2), is concerned with the optimal use of resour-
ces for disease care and health promotion. Health
economics approaches the health service provision
from two perspectives. The first corresponds to the
use of microeconomic tools to explain the behavior
of the health sector as an industrial medical com-
plex. The second considers health as a component
of wellbeing and directs its analysis to the use of
macroeconomic tools and human capital theories.
In this approach, it is necessary to analyze the needs
of health care for the population and determine in
a clear and coherent way the economic interrela-
tion between the participants of the provision of
public and private health services. The compre-
hensive analysis of risk factors and costs of chronic
and catastrophic diseases, cost effectiveness, bene-
fit coverage and limitations of Telehealth and tele-
medicine, as well as the efficiency in the provision
and coordination of services by Telehealth is thus
127
Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in
Telehealth
needed to develop a coherent economic and busi-
ness model of use of Telehealth technologies. The
Telehealth model needs to take into account the
main elements in health economics as illustrated
Figure 1. Main elements in health economics.
Fuente. Extracted from (3).
by the work by Williams [3, 4] in Figure 1. Those
elements need to be considered in the development
of business models for the implementation of new
technologies in healthcare.
128
NOVA. 2017; 15 (28): 125-136
Viewing healthcare as an industrial medical com-
plex where healthcare is the product being delive-
red, the provision of healthcare has the following
business and production factors:
• Necessity (urgent, life sustainable, non
critical for life)
• Demand and Supply (access to products
and services)
• Quality (effectiveness and efficacy)
• Performance (service levels, service offe-
rings)
• Reliability (confidence in the interven-
tions)
• Availability (opportunity, service delivery,
time for delivery, service coordination)
• Market value (healthcare market value)
• Production cost (healthcare cost)
• Adoption cost (training cost, cost of
ecosystem change)
• Product operating cost (recurring services)
• Maintenance cost (monitoring cost, pre-
vention and promotion activities)
• System economics (financial resources,
reimbursement, allocations)
• Profit
Technology innovations and models that create
value by improving some of those healthcare pro-
duction indicators have a chance to be accepted
and adopted by healthcare operators and adminis-
trators. The main health economics factors to take
into account in the introduction and adoption of
new Telehealth applications and systems are as fo-
llows:
Perceived value. Achieving high value for patients
must become the overarching goal of health care
delivery, with value defined as the health outco-
mes achieved per dollar spent (5). Every deplo-
yed technology has a perceived value, which is
connected to benefits. Operational savings, cus-
tomer satisfaction improvements, reduction in
costs, reduction in service delivery time, as well as
improvements in service coordination are viewed
as benefits. In technology, the perceived value is
also a manifestation of how a system can provi-
de the same benefits of an older system but at a
higher performance level. The perceived value is
not usually the same as the cost of running the
system. Thus, technology companies need to be
willing to adjust their prices in the introduction
of new technologies in lieu of gaining experience,
optimizing the system and capturing additional
requirements, which may improve the product
functionality and thus customer interest.
Market equilibrium. In healthcare, when the
quantities supplied and demanded are equal the
system is in equilibrium. Although the definition
is straight forward, for health economics the equi-
librium is a complex process due to the players in
the system, and government and insurance com-
panies partially covered the cost (6). When new
healthcare technologies or products are introdu-
ced, it takes some time for the technology to be
positioned, accepted and adopted. Initial custo-
mers (we called them “innovators”) acquiring the
technology are few but willing to use the product
and be part of the optimization process. As the
technology matures, more customer and compe-
tition is brought and eventually the market price
levels. There is a point where the market satura-
tes and there is no more room for competition or
lower prices. High prices can be sustained if there
is a sole supplier of goods, the industry sector eco-
nomics allow it and the technology, performance
and reliability exceed the competition.
Adoption cost. This is crucial for the new tech-
nologies that require changes or upgrades to the
ecosystem to perform (7). In the case of Teleme-
dicine, many isolated and suburban regions lack
of connectivity to perform live interconsultation,
or require costly equipment to operate. Thus, the
adoption cost may be prohibitive for a successful
implementation of the technology. In many cases,
Telemedicine services are not easily self-sustaina-
ble in those regions with a small population due
to initial investment as well as maintenance and
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Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in
Telehealth
operating cost to deploy and operate the required
infrastructure.
System economics. Even if a product has a hi-
gh-perceived value, the health economics determi-
nes if the new product or technology has a chance
to be acquired (8, 9). Careful analysis of the ecosys-
tem may indicate that the new product can effi-
ciently and gradually replace other components of
the ecosystem, thus balancing the investment and
the available budget. If budget restrictions occur,
smaller components or functionality of the new
product may be offered in lieu of demonstrating
its potential to provide benefits and create value.
A list of economic factors influencing the adop-
tion of new technologies include:
• Cost versus benefits of the new technology
compared to existing technology
• Implementation and maintenance costs
• New system performance versus old system
performance
• Demand and supply
• Macro and micro economic impact of the
deployed solutions
• Health economics and available budget for
improvements
• Ecosystem economics and budget balan-
cing
• Short term and long term return of invest-
ment
The trend in the development of health econo-
mics research shows a great dedication to monito-
ring and evaluation elements related to the health
system, emphasizing aspects of demand (access),
while a more detailed analysis is not clearly seen in
aspects such as economic evaluation and market
equilibrium (10). At present, Colombia is more
concerned with the evaluation of the healthcare
system than with other aspects. However in recent
years written research on health economics has
focused on economic evaluation, market analy-
sis and determinants of health. Research areas in
economic evaluation of health technologies, mea-
surement of results, health policy research, econo-
mic prediction, measurement techniques and the
assessment of preferences for health status is also
of importance in the evaluation of new healthcare
technologies such as Telehealth.
Telehealth Technologies
Facing the reality of the problem of the health ser-
vices sector in Colombia, we can see the emergen-
ce of information and communication technolo-
gies in health or ICTs for the provision of health
services to the most vulnerable, disadvantaged and
isolated populations in Colombia. ICTs have the
potential to improve service coverage, facilitate
service coordination, improve efficiency, contri-
bute to effective and timely registration and di-
sease control, and facilitate the establishment and
operation of health promotion and prevention
programs. (11-12). The offer of health services by
Telehealth has the potential to become a favora-
ble and important factor and therefore its scope,
where limitations and benefits must be analyzed
and studied for a greater impact on the health eco-
nomy in Colombia.
Multiple information and communication tech-
nologies are being now introduced in healthcare
settings (12). Communication tools such as chat,
email, text messages, video chat, group chat have
successfully being used in other type of industries
such as entertainment, business and education,
and are now being introduced to various clinical
applications for coaching, remote consultation,
medication reminders, monitoring, physician
education, and many others (13-15). Main tech-
nological advancements that have allowed new
products and applications in healthcare include:
• Internet access and capacity at reduced cost
• Sensors and devices
• Mobile computing and mobile technologies
• Connectivity and interfaces for integration
of technologies
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NOVA. 2017; 15 (28): 125-136
• Internet of things
• Health information highways for data sha-
ring
• Data and information storage systems
• Data analytics and healthcare informatics
• Content management
• Prediction and expert systems for decision
making
Exploiting the potential of digital and commu-
nication technologies in healthcare, the goal is to
obtain and process data to generate information
that can be used in optimal healthcare services,
patient education and clinical decision making
processes faster and better anytime anywhere. For
example, using wearable sensors coupled with mo-
bile devices, patient physical variables can be cap-
tured ubiquuosly and data and information can
be processed and transmitted in real time for their
clinical use. Information can be received, combi-
ned with other applications’ data, integrated into
the patient medical record and transmitted to the
attending physician for instant evaluation and re-
commendation of diagnosis or treatment. Educa-
tional content can automatically be pushed to the
patient mobile phone for patient education.
The main challenge for the development and
adoption of Telehealth technologies is to articula-
te the technologies, tools and systems in a model of
attention and provision of services in such a way that
they are integrated in an effective and efficient way
for the service of the individual. Another important
aspect is how the new technology or product inte-
grates with the ecosystem, and if requires changes
or expansion of the ecosystem to operate. This can
be seen in the deployment of telehealth solutions
to underserved populations that lack access to In-
ternet services. To efficiently introduce solutions,
it is required that remote hospitals and healthcare
settings have access to internet, and that electronic
medical records have been implemented and used.
Use of smart phone applications by the elderly is
limited in low income populations as they have
not being exposed to new information and com-
munication technologies and their efficient and
effective use is impaired.
Analyzing the way technology has impacted the
provision of healthcare services, we can group the
progression into three major models or momen-
tums, as shown in Figure 2: 1) conventional heal-
thcare services where individuals receive health
services in hospitals and healthcare settings. This
is an interventionist model of attention and the-
re is no preventtion of disease or promotion of
health programs; 2) Telecare services where expert
consultation and diagnosis is provided to patients
and healthcare professionals, via information and
communication technologies. This model of servi-
ce is faster, more convenient and increases covera-
ge of services. Teleconsultation and Telecare techno-
logies need to be validated and optimized for specific
clinical applications. Adoption of the technologies is
limited by the effective demand that covers physician
costs, technologies and infrastructure; 3) Telehealth
applications where the individual is concerned
about his/her own health. The individual becomes
self educated and engaged on promotion of health
and prevention of disease programs, searches heal-
th information, diets and participates in physical
and mental activities, wear wireless sensors that
monitor variables, and does interconsultations
online with health professionals and coaches. The
number of Telehealth users is prompt to grow as
more people are advocating for their own heal-
th, more mobile and Web applications are being
offered, and and no major changes to the ecosys-
tem are required. There is potential for a growing
number of applications that can be integrated and
articulated effectively using Web interfaces, heal-
thcare information highways and their business
and economic models fit within the healthcare
ecosystem.
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Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in
Telehealth
Disruptive Innovation
The health care industry is in need of a systemic
change in the economic, business and management
models. Many healthcare operators, health insu-
rance and management companies lose millions of
dollars every year. Health care service provision is
not efficient, is not effective, is delayed, expensi-
ve, lacks of opportunity and resolutive power and,
thus, frustrating to many patients, especially those
of low-income that cannot afford prepaid services.
Disruptive innovations in healthcare service ma-
nagement, provision and coordination could help
solve or mitigate the crisis (16). We are in need
of disruption in many areas of healthcare services
including service coordination, coverage, service
level integration, prevention of disease and pro-
motion of health programs, and patient engage-
ment, between others, so the new system is more
efficient and offers lower costs, higher quality, and
greater convenience than the conventional system
is capable of offering. The opportunity for dis-
ruptive innovation is there but adoption of new
technology models that could solve the problem is
slow, non-occurring or not being widely accepted.
*Disruptive Innovations in Healthcare
Disruptive innovations are usually created by sma-
ll companies trying to solve a problem or improve
a service using a new concept, service model or
Figure 2. Progression of access to healthcare services.
technology. While the main industry leaders are
focused on gradually improving their products or
services, adding more features to the point where
the average consumer is not greatly affected, they
miss simpler, more convenient, and less costly offe-
rings to the low end of the market. As the new tech-
nology or models are tested, improved and used
over time, they get better to the point that they
meet the needs of a large number of users (17-
20). Recent potential disruptive innovations are
seen in a greatly successful and recently created
health insurance replacement company in Colom-
bia, where their business model is to offer prepaid
discounted prices to the low-income population,
giving them access to a large network of doctors
with fast response times (21). This is opposed to
traditional prepaid medical insurance with high
premiums and deductibles that do not meet the
needs of the low-end markets. In the diagnostics
industry, small research companies are creating
new rapid diagnostics and screening tools for
home use, instead of large systems for hospitals,
appealing and attracting a large base line of cus-
tomers instead of reaching out to a small number
of customers in hospital settings where they face
fierce competition.
*Disruptive innovations in Telehealth
As specialist physicians are devoted to diagno-
se and treat complex illnesses, less-skilled health
132
NOVA. 2017; 15 (28): 125-136
professionals could take on more complex roles
than they are currently being allowed to do, given
that they can interact with specialists. Nowadays,
nurse practitioners are capable of treating many
ailments that used to require a physician’s care.
Using Telehealth technologies, the health system
could make expert consultation services faster,
more accessible, more efficient and at lower cost.
Telehealth services could use less skilled practitio-
ners at the remote patient side and connect to a
specialist for an expert advice that can save lives.
Coaching and wellness programs can also bene-
fit from Telehealth technologies allowing a large
number of users to care for their health, providing
users with instant communication, information,
content and tools for better engagement in heal-
thy programs. Recent trends in wellness programs
by insurance companies is to provide rewards to
the insured when self monitoring their health,
participating in wellness sessions, setting up goals
to reduce weight through gamificacion schemes
[5]. This represents long-term savings to insurance
companies, as participating people are less prompt
for disease and doctor’s visits. Some innovations
of exactly this sort have transformed pockets of
the health care system, and where they have ha-
ppened, higher quality, greater convenience, and
lower cost actually have been achieved.
In order for a disruptive innovation to succeed,
the associated ecosystem needs to allow it. Disrup-
tive technologies require a value network, which
consists of infrastructure and industry players that
will make use of the new technology and model.
Usually disruptive technologies are not compa-
tible with established value networks and, thus,
they need to create a new value network. The per-
formance of the old system needs to be surpassed
by the needs of the market and by the performan-
ce of the new system as well. In Telemedicine, for
example, provision of expert interconsultation in
remote regions is the natural way to provide servi-
ces in underserved populations, and it seems to be
the next model of service. However, the ecosystem
requires connectivity, adequate bandwidth, access
to constant energy source and implementation of
electronic medical records in the rural population.
It also requires a sustainable business and reim-
bursement model to succeed. In a low population
scenario, if Telemedicine infrastructure costs are
high and usability is low compared to conventio-
nal health service models, the conventional service
may be sufficient where patients travel to urban
places to get services from high-level hospital se-
ttings. In addition, the Telehealth service model
disruption may be blocked by other components
of the ecosystem such as aerial ambulances, which
may find in Telehealth a threat to their service and
business models.
The following main factors are needed for a dis-
ruptive innovation in Telehealth to succeed:
• Ecosystem needs minor or no changes for
the innovation to be adopted.
• Business models need to be created, and
government regulations need to allow it,
for fast and easy reimbursement for ROI.
• It needs to offer clear performance impro-
vements and advantages over traditional
service models, in some specific areas. For
example, it may be an increase in usability,
accessibility, cost or personalization. The
1DOC3 disruptive innovation (22) does
not replace a traditional medical consul-
tation but it is highly usable, more con-
venient and fast, so it offers advantages in
another context of use compared to con-
ventional health services.
• The cost is less than traditional systems
offering similar services.
• Takes into account other business compo-
nents of the ecosystem to avoid blockage.
• Creates value and benefits to the low end
of the market.
Based on those factors described above, some Te-
lehealth solutions can find the space for disruptive
innovation. Some successful Telehealth solutions
that target a large number of users, not only un-
133
Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in
Telehealth
derserved populations, have found great acceptan-
ce. As an example, the 1Doc3.com service [4] who
offers free medical advice through an online plat-
form has greatly captured a large number of users.
The ecosystem requires no changes for 1Doc3.
com to be adopted since it requires only an Inter-
net connection for the user. However, nowadays
Facebook and Tigo are offering free internet for
low rural settings for these type of applications.
As the customer base is not restricted to rural po-
pulations, the disruptive innovation is growing in
users and in acceptance. In addition, this servi-
ce is not displacing other business services in the
ecosystem thus it is possible that it finds good le-
verage and alliances with industry leaders for the
offering of complementary services.
Technology Adoption
Figure 3 illustrates the adoption of new techno-
logies in the health industry as time progresses.
Innovators are industry leaders in the market im-
A mathematical model for the behavior described
above was developed and shown below:
Where P(t) is the performance over time t. The
delay variable t specifies the time for the type of
customer to start adopting the new technology.
plementing and adopting the latest technologies
advance or adopt first. As technology adoption
needs multiple iterations for optimal use, the per-
formance improvement seen by early adopters will
fluctuate in an uprising oscillating manner. This
is due to required changes in the related ecosys-
tems so the new technology can have sustainable
growth. Market followers, in the second category,
will introduce new technologies after the market
innovation leaders have entered and proved the
concept. This group does not want to risk per-
formance given by old systems in exchange for a
more risky adventure- greater performance offe-
ring of new technologies. As technology matures,
the oscillation is less dramatic as well as the pace
of performance improvement over time. In the
last group, the late adopters do not see a rapidly
change in performance over time, as their prefe-
rence is to keep old systems and models working
until the new technologies have reached maturity
and other users have proven the concept.
Figure 3. Progression of adoption of disruptive technologies.
The factors α and β are related to the speed to
obtain the desired performance and to the rate of
iterations to get the new technology adopted in
the ecosystem.
Figure 4 shows and illustration of health care ser-
vice provision evolution. In the conventional mo-
del, patients visit a hospital or health professional
134
NOVA. 2017; 15 (28): 125-136
for diagnosis and treatment. In this scenario, heal-
thy people do not usually visit healthcare facilities.
In the second scenario, the patient first educates
himself, remotely interacts with health counselor
or physician, then obtains a preliminary diagno-
sis or knowledge about his/her condition, and last
goes to a hospital for lab tests, confirmed diag-
nosis, and treatment. In the more recent model,
The number of users of conventional healthcare
mainly comes from people or populations with
disease conditions as prevention of disease and
promotion of health programs are not effective or
massively used. Telemedicine applications slowly
grow in number of users, especially those in rural
or underserved regions as they also relate to people
with conditions that require a specialist attention.
In contrast, Telehealth users are growing at a fast
pace, as wellness programs are being more accepted
and widely used. We expect the number of users of
Telehealth applications to outnumber the number
of users in conventional health service provision.
Projected Trends
• Conventional healthcare service provision
will mainly be relevant for advanced diag-
the individual is proactive to his/her condition
and health, participates and engages in wellness
programs and activities, monitors his/her wellness
state, and in case of disease condition, does inter-
consultation, and visits a healthcare professional
and setting for diagnosis and intervention. Reco-
very is performed at home.
Figure 4. Healthcare technologies.
nosis and treatment that require adequate
equipment and resources. In this health
service provision, the number of users
compared to most of the population will
be lower.
• Telemedicine and teleconsultation servi-
ces will be on the rise for coverage of the
remote and underserved population, where
access to expert consultation is limited.
The number of clinical applications will be
increased.
• Telehealth and wellness applications, servi-
ces and users will be on the rise, surpassing
the number of users of conventional heal-
thcare settings. The trend is to engage indi-
vidual in wellness programs so the users are
more aware of their health and participate
in prevention of disease and promotion of
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Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in
Telehealth
health programs. The trend is to incorpo-
rate wellness programs in schools, corpo-
rate offices, gymnasiums, parks, malls and
stores for accessibility, low cost and massive
use.
• From the technology point of view, we
expect great development of communica-
tion protocols, mobile health applications,
Internet of Things IOTs applications,
information highways, and integration of
applications through common communi-
cation interfaces.
• Big Data analytics, clinical analytics, public
health analytics will be on the rise for au-
tomated decision making, coordination of
services, and development of health pro-
vision programs according to the needs of
the population.
Questions to Ask
In order to introduce new ICT tools, models and
concepts in Telehealth, the following questions
should be initially asked
• How can a ICTs impact the coverage and
quality of service provided by public and
private entities, as well as the cost effecti-
veness, benefit and utility of the delivery of
health services?
• How can health promotion and prevention
activities by Telehealth improve the health
economy in Colombia?
• Under what conditions and limitations
does Telehealth have the potential to bene-
fit the health economy?
• What are the macroeconomic benefits and
benefits of the provision of services and the
establishment of health programs through
Telehealth?
• Which areas of Telehealth in the panorama
of health services delivery in Colombia
have a greater possibility of improving the
health economy?
Acknowledgement
This research has been supported by the School of
Health, Universidad Nacional Abierta y a Distan-
cia UNAD, Bogotá, Colombia.
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Analysis Of Economic And Business Factors Influencing Disruptive Innovation In Telehealth

  • 1. 125 Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth Análisis de factores económicos y empresariales que influyen la Innovación Disruptiva en Telesalud Abstract Objective. Analysis of economic and business factors influencing disruption innovation in healthcare taking as a reference Telehealth systems and technologies. Methods. Analysis of economic and business decision factors that influence the adoption of new technologies are qualitatively analyzed using as a case example Telehealth systems. Results. Main factors for the adoption of new technologies in healthcare are identified and analyzed. Factors include new technology adoption cost, usability, perceived value, competitive systems, old systems competitive cost and performance, and type of users, between others. Keywords: Telehealth systems, Technology adoption, Disruptive innovation, Ecosystems. Resumen Objetivo: análisis de los factores que influyen en la adopción de nuevas tecnologías en el cuidado de la salud tomando como referencia la Telesalud o el uso de las tecnologías de la información y la comunicación en la asistencia sanitaria. Métodos: el análisis de los factores de decisión económica y empresarial que influyen en la adopción de nuevas tecnologías se analiza cualitativamente utilizando como ejemplo de caso los sistemas de Telehealth. Resultados: se identifican y analizan los principales factores para la adopción de nuevas tecnologías en la atención de la salud por Telesalud. Los factores incluyen costo de adopción de nuevas tecnologías, usabilidad, valor percibido, sistemas competitivos, costos y desempeño competitivos de los sistemas actuales, y tipo de usuarios, entre otros. Palabras clave: telesalud, adopción tecnológica, innovación disruptiva, ecosistemas Jorge Millan1,2 , PhD; Leonardo1 Yunda, PhD; Andrés Valencia2 1. Bioinnova Group, School of Health – Universidad Nacional Abierta y a Distancia UNAD, Bogotá, Colombia. 2. Sigma Biomedical, Hialeah, Florida – USA. Correspondencia: jmillan@sigmabiomedical.com - leyunda@ieee.org Articulo original producto de la investigación Recibido: 20/03/2017 Aceptado: 01/08/2017
  • 2. 126 NOVA. 2017; 15 (28): 125-136 Introduction The Colombian healthcare system faces great cha- llenges and difficulties, and thus, new methods, models, and tools need to be developed, introdu- ced and adopted to improve the efficiency, quality and opportunity of healthcare service provision. The challenges are mainly related to the resources committed in the health sector and the efficiency in their use, which not only affect health status, but also the welfare and economic growth of the population. Government health policies and regu- lations, which define the schemes, systems, com- ponents and elements of the health system, and define the modalities of health insurance, finan- cing of health services, coverage for the poor, and the management of private and public institutions in the provision of services, need to begin a pro- cess of restructuring to prevent a collapse of the health system in Colombia. A main issue is how to maximize the wellness of the population by providing quality and timely health services using existing resources. Health- care service provision is reflected in the coverage and quality of the service provided by public and private entities, cost effectiveness, as well as bene- fit and utility. The health service provision must be studied from a broad sense. The study needs to analyze current health economics in Colom- bia and the economic impact of new technolo- gies such as Telehealth have in the provision of services. In the panel “Hacia un Plan País en Te- lesalud” (Towards a Country Plan in Telehealth) (1), the ministries of Communications and Social Protection discuss the future of the provision of health services through Information and Com- munication Technologies (ICT). The benefits of a Telehealth system are varied. In addition to ex- panding the coverage and access of the system to the poorest, they allow specialized and quality care to these populations. Telehealth can become an effective and efficient strategy to reduce costs and decongest the health system in Colombia, given that appropriate investment is performed for the required equipment, infrastructure and changes in the organizational structure. Although new information and communication technologies and applications have emerged in the last decade in areas such as education, commerce, business, entertainment, government and healthca- re, their practical implementation and widespread adoption and use in healthcare have not happened rapidly. Multiple factors may influence the deci- sion of healthcare operators and administrators on acquiring and implementing new Telehealth products and technologies. Careful analysis of the factors influencing adoption is important for both solution developers and health care providers for optimal use of their investment. Factors include a) health economics dynamics, b) effective implemen- tation of Telehealth technologies as new healthcare models, and c) the way disruptive innovation in- fluences widespread use of new technologies. These main factors are analyzed and discussed in the fo- llowing sections. Health Economics Health economics, as defined by Selma Mushkin (2), is concerned with the optimal use of resour- ces for disease care and health promotion. Health economics approaches the health service provision from two perspectives. The first corresponds to the use of microeconomic tools to explain the behavior of the health sector as an industrial medical com- plex. The second considers health as a component of wellbeing and directs its analysis to the use of macroeconomic tools and human capital theories. In this approach, it is necessary to analyze the needs of health care for the population and determine in a clear and coherent way the economic interrela- tion between the participants of the provision of public and private health services. The compre- hensive analysis of risk factors and costs of chronic and catastrophic diseases, cost effectiveness, bene- fit coverage and limitations of Telehealth and tele- medicine, as well as the efficiency in the provision and coordination of services by Telehealth is thus
  • 3. 127 Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth needed to develop a coherent economic and busi- ness model of use of Telehealth technologies. The Telehealth model needs to take into account the main elements in health economics as illustrated Figure 1. Main elements in health economics. Fuente. Extracted from (3). by the work by Williams [3, 4] in Figure 1. Those elements need to be considered in the development of business models for the implementation of new technologies in healthcare.
  • 4. 128 NOVA. 2017; 15 (28): 125-136 Viewing healthcare as an industrial medical com- plex where healthcare is the product being delive- red, the provision of healthcare has the following business and production factors: • Necessity (urgent, life sustainable, non critical for life) • Demand and Supply (access to products and services) • Quality (effectiveness and efficacy) • Performance (service levels, service offe- rings) • Reliability (confidence in the interven- tions) • Availability (opportunity, service delivery, time for delivery, service coordination) • Market value (healthcare market value) • Production cost (healthcare cost) • Adoption cost (training cost, cost of ecosystem change) • Product operating cost (recurring services) • Maintenance cost (monitoring cost, pre- vention and promotion activities) • System economics (financial resources, reimbursement, allocations) • Profit Technology innovations and models that create value by improving some of those healthcare pro- duction indicators have a chance to be accepted and adopted by healthcare operators and adminis- trators. The main health economics factors to take into account in the introduction and adoption of new Telehealth applications and systems are as fo- llows: Perceived value. Achieving high value for patients must become the overarching goal of health care delivery, with value defined as the health outco- mes achieved per dollar spent (5). Every deplo- yed technology has a perceived value, which is connected to benefits. Operational savings, cus- tomer satisfaction improvements, reduction in costs, reduction in service delivery time, as well as improvements in service coordination are viewed as benefits. In technology, the perceived value is also a manifestation of how a system can provi- de the same benefits of an older system but at a higher performance level. The perceived value is not usually the same as the cost of running the system. Thus, technology companies need to be willing to adjust their prices in the introduction of new technologies in lieu of gaining experience, optimizing the system and capturing additional requirements, which may improve the product functionality and thus customer interest. Market equilibrium. In healthcare, when the quantities supplied and demanded are equal the system is in equilibrium. Although the definition is straight forward, for health economics the equi- librium is a complex process due to the players in the system, and government and insurance com- panies partially covered the cost (6). When new healthcare technologies or products are introdu- ced, it takes some time for the technology to be positioned, accepted and adopted. Initial custo- mers (we called them “innovators”) acquiring the technology are few but willing to use the product and be part of the optimization process. As the technology matures, more customer and compe- tition is brought and eventually the market price levels. There is a point where the market satura- tes and there is no more room for competition or lower prices. High prices can be sustained if there is a sole supplier of goods, the industry sector eco- nomics allow it and the technology, performance and reliability exceed the competition. Adoption cost. This is crucial for the new tech- nologies that require changes or upgrades to the ecosystem to perform (7). In the case of Teleme- dicine, many isolated and suburban regions lack of connectivity to perform live interconsultation, or require costly equipment to operate. Thus, the adoption cost may be prohibitive for a successful implementation of the technology. In many cases, Telemedicine services are not easily self-sustaina- ble in those regions with a small population due to initial investment as well as maintenance and
  • 5. 129 Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth operating cost to deploy and operate the required infrastructure. System economics. Even if a product has a hi- gh-perceived value, the health economics determi- nes if the new product or technology has a chance to be acquired (8, 9). Careful analysis of the ecosys- tem may indicate that the new product can effi- ciently and gradually replace other components of the ecosystem, thus balancing the investment and the available budget. If budget restrictions occur, smaller components or functionality of the new product may be offered in lieu of demonstrating its potential to provide benefits and create value. A list of economic factors influencing the adop- tion of new technologies include: • Cost versus benefits of the new technology compared to existing technology • Implementation and maintenance costs • New system performance versus old system performance • Demand and supply • Macro and micro economic impact of the deployed solutions • Health economics and available budget for improvements • Ecosystem economics and budget balan- cing • Short term and long term return of invest- ment The trend in the development of health econo- mics research shows a great dedication to monito- ring and evaluation elements related to the health system, emphasizing aspects of demand (access), while a more detailed analysis is not clearly seen in aspects such as economic evaluation and market equilibrium (10). At present, Colombia is more concerned with the evaluation of the healthcare system than with other aspects. However in recent years written research on health economics has focused on economic evaluation, market analy- sis and determinants of health. Research areas in economic evaluation of health technologies, mea- surement of results, health policy research, econo- mic prediction, measurement techniques and the assessment of preferences for health status is also of importance in the evaluation of new healthcare technologies such as Telehealth. Telehealth Technologies Facing the reality of the problem of the health ser- vices sector in Colombia, we can see the emergen- ce of information and communication technolo- gies in health or ICTs for the provision of health services to the most vulnerable, disadvantaged and isolated populations in Colombia. ICTs have the potential to improve service coverage, facilitate service coordination, improve efficiency, contri- bute to effective and timely registration and di- sease control, and facilitate the establishment and operation of health promotion and prevention programs. (11-12). The offer of health services by Telehealth has the potential to become a favora- ble and important factor and therefore its scope, where limitations and benefits must be analyzed and studied for a greater impact on the health eco- nomy in Colombia. Multiple information and communication tech- nologies are being now introduced in healthcare settings (12). Communication tools such as chat, email, text messages, video chat, group chat have successfully being used in other type of industries such as entertainment, business and education, and are now being introduced to various clinical applications for coaching, remote consultation, medication reminders, monitoring, physician education, and many others (13-15). Main tech- nological advancements that have allowed new products and applications in healthcare include: • Internet access and capacity at reduced cost • Sensors and devices • Mobile computing and mobile technologies • Connectivity and interfaces for integration of technologies
  • 6. 130 NOVA. 2017; 15 (28): 125-136 • Internet of things • Health information highways for data sha- ring • Data and information storage systems • Data analytics and healthcare informatics • Content management • Prediction and expert systems for decision making Exploiting the potential of digital and commu- nication technologies in healthcare, the goal is to obtain and process data to generate information that can be used in optimal healthcare services, patient education and clinical decision making processes faster and better anytime anywhere. For example, using wearable sensors coupled with mo- bile devices, patient physical variables can be cap- tured ubiquuosly and data and information can be processed and transmitted in real time for their clinical use. Information can be received, combi- ned with other applications’ data, integrated into the patient medical record and transmitted to the attending physician for instant evaluation and re- commendation of diagnosis or treatment. Educa- tional content can automatically be pushed to the patient mobile phone for patient education. The main challenge for the development and adoption of Telehealth technologies is to articula- te the technologies, tools and systems in a model of attention and provision of services in such a way that they are integrated in an effective and efficient way for the service of the individual. Another important aspect is how the new technology or product inte- grates with the ecosystem, and if requires changes or expansion of the ecosystem to operate. This can be seen in the deployment of telehealth solutions to underserved populations that lack access to In- ternet services. To efficiently introduce solutions, it is required that remote hospitals and healthcare settings have access to internet, and that electronic medical records have been implemented and used. Use of smart phone applications by the elderly is limited in low income populations as they have not being exposed to new information and com- munication technologies and their efficient and effective use is impaired. Analyzing the way technology has impacted the provision of healthcare services, we can group the progression into three major models or momen- tums, as shown in Figure 2: 1) conventional heal- thcare services where individuals receive health services in hospitals and healthcare settings. This is an interventionist model of attention and the- re is no preventtion of disease or promotion of health programs; 2) Telecare services where expert consultation and diagnosis is provided to patients and healthcare professionals, via information and communication technologies. This model of servi- ce is faster, more convenient and increases covera- ge of services. Teleconsultation and Telecare techno- logies need to be validated and optimized for specific clinical applications. Adoption of the technologies is limited by the effective demand that covers physician costs, technologies and infrastructure; 3) Telehealth applications where the individual is concerned about his/her own health. The individual becomes self educated and engaged on promotion of health and prevention of disease programs, searches heal- th information, diets and participates in physical and mental activities, wear wireless sensors that monitor variables, and does interconsultations online with health professionals and coaches. The number of Telehealth users is prompt to grow as more people are advocating for their own heal- th, more mobile and Web applications are being offered, and and no major changes to the ecosys- tem are required. There is potential for a growing number of applications that can be integrated and articulated effectively using Web interfaces, heal- thcare information highways and their business and economic models fit within the healthcare ecosystem.
  • 7. 131 Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth Disruptive Innovation The health care industry is in need of a systemic change in the economic, business and management models. Many healthcare operators, health insu- rance and management companies lose millions of dollars every year. Health care service provision is not efficient, is not effective, is delayed, expensi- ve, lacks of opportunity and resolutive power and, thus, frustrating to many patients, especially those of low-income that cannot afford prepaid services. Disruptive innovations in healthcare service ma- nagement, provision and coordination could help solve or mitigate the crisis (16). We are in need of disruption in many areas of healthcare services including service coordination, coverage, service level integration, prevention of disease and pro- motion of health programs, and patient engage- ment, between others, so the new system is more efficient and offers lower costs, higher quality, and greater convenience than the conventional system is capable of offering. The opportunity for dis- ruptive innovation is there but adoption of new technology models that could solve the problem is slow, non-occurring or not being widely accepted. *Disruptive Innovations in Healthcare Disruptive innovations are usually created by sma- ll companies trying to solve a problem or improve a service using a new concept, service model or Figure 2. Progression of access to healthcare services. technology. While the main industry leaders are focused on gradually improving their products or services, adding more features to the point where the average consumer is not greatly affected, they miss simpler, more convenient, and less costly offe- rings to the low end of the market. As the new tech- nology or models are tested, improved and used over time, they get better to the point that they meet the needs of a large number of users (17- 20). Recent potential disruptive innovations are seen in a greatly successful and recently created health insurance replacement company in Colom- bia, where their business model is to offer prepaid discounted prices to the low-income population, giving them access to a large network of doctors with fast response times (21). This is opposed to traditional prepaid medical insurance with high premiums and deductibles that do not meet the needs of the low-end markets. In the diagnostics industry, small research companies are creating new rapid diagnostics and screening tools for home use, instead of large systems for hospitals, appealing and attracting a large base line of cus- tomers instead of reaching out to a small number of customers in hospital settings where they face fierce competition. *Disruptive innovations in Telehealth As specialist physicians are devoted to diagno- se and treat complex illnesses, less-skilled health
  • 8. 132 NOVA. 2017; 15 (28): 125-136 professionals could take on more complex roles than they are currently being allowed to do, given that they can interact with specialists. Nowadays, nurse practitioners are capable of treating many ailments that used to require a physician’s care. Using Telehealth technologies, the health system could make expert consultation services faster, more accessible, more efficient and at lower cost. Telehealth services could use less skilled practitio- ners at the remote patient side and connect to a specialist for an expert advice that can save lives. Coaching and wellness programs can also bene- fit from Telehealth technologies allowing a large number of users to care for their health, providing users with instant communication, information, content and tools for better engagement in heal- thy programs. Recent trends in wellness programs by insurance companies is to provide rewards to the insured when self monitoring their health, participating in wellness sessions, setting up goals to reduce weight through gamificacion schemes [5]. This represents long-term savings to insurance companies, as participating people are less prompt for disease and doctor’s visits. Some innovations of exactly this sort have transformed pockets of the health care system, and where they have ha- ppened, higher quality, greater convenience, and lower cost actually have been achieved. In order for a disruptive innovation to succeed, the associated ecosystem needs to allow it. Disrup- tive technologies require a value network, which consists of infrastructure and industry players that will make use of the new technology and model. Usually disruptive technologies are not compa- tible with established value networks and, thus, they need to create a new value network. The per- formance of the old system needs to be surpassed by the needs of the market and by the performan- ce of the new system as well. In Telemedicine, for example, provision of expert interconsultation in remote regions is the natural way to provide servi- ces in underserved populations, and it seems to be the next model of service. However, the ecosystem requires connectivity, adequate bandwidth, access to constant energy source and implementation of electronic medical records in the rural population. It also requires a sustainable business and reim- bursement model to succeed. In a low population scenario, if Telemedicine infrastructure costs are high and usability is low compared to conventio- nal health service models, the conventional service may be sufficient where patients travel to urban places to get services from high-level hospital se- ttings. In addition, the Telehealth service model disruption may be blocked by other components of the ecosystem such as aerial ambulances, which may find in Telehealth a threat to their service and business models. The following main factors are needed for a dis- ruptive innovation in Telehealth to succeed: • Ecosystem needs minor or no changes for the innovation to be adopted. • Business models need to be created, and government regulations need to allow it, for fast and easy reimbursement for ROI. • It needs to offer clear performance impro- vements and advantages over traditional service models, in some specific areas. For example, it may be an increase in usability, accessibility, cost or personalization. The 1DOC3 disruptive innovation (22) does not replace a traditional medical consul- tation but it is highly usable, more con- venient and fast, so it offers advantages in another context of use compared to con- ventional health services. • The cost is less than traditional systems offering similar services. • Takes into account other business compo- nents of the ecosystem to avoid blockage. • Creates value and benefits to the low end of the market. Based on those factors described above, some Te- lehealth solutions can find the space for disruptive innovation. Some successful Telehealth solutions that target a large number of users, not only un-
  • 9. 133 Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth derserved populations, have found great acceptan- ce. As an example, the 1Doc3.com service [4] who offers free medical advice through an online plat- form has greatly captured a large number of users. The ecosystem requires no changes for 1Doc3. com to be adopted since it requires only an Inter- net connection for the user. However, nowadays Facebook and Tigo are offering free internet for low rural settings for these type of applications. As the customer base is not restricted to rural po- pulations, the disruptive innovation is growing in users and in acceptance. In addition, this servi- ce is not displacing other business services in the ecosystem thus it is possible that it finds good le- verage and alliances with industry leaders for the offering of complementary services. Technology Adoption Figure 3 illustrates the adoption of new techno- logies in the health industry as time progresses. Innovators are industry leaders in the market im- A mathematical model for the behavior described above was developed and shown below: Where P(t) is the performance over time t. The delay variable t specifies the time for the type of customer to start adopting the new technology. plementing and adopting the latest technologies advance or adopt first. As technology adoption needs multiple iterations for optimal use, the per- formance improvement seen by early adopters will fluctuate in an uprising oscillating manner. This is due to required changes in the related ecosys- tems so the new technology can have sustainable growth. Market followers, in the second category, will introduce new technologies after the market innovation leaders have entered and proved the concept. This group does not want to risk per- formance given by old systems in exchange for a more risky adventure- greater performance offe- ring of new technologies. As technology matures, the oscillation is less dramatic as well as the pace of performance improvement over time. In the last group, the late adopters do not see a rapidly change in performance over time, as their prefe- rence is to keep old systems and models working until the new technologies have reached maturity and other users have proven the concept. Figure 3. Progression of adoption of disruptive technologies. The factors α and β are related to the speed to obtain the desired performance and to the rate of iterations to get the new technology adopted in the ecosystem. Figure 4 shows and illustration of health care ser- vice provision evolution. In the conventional mo- del, patients visit a hospital or health professional
  • 10. 134 NOVA. 2017; 15 (28): 125-136 for diagnosis and treatment. In this scenario, heal- thy people do not usually visit healthcare facilities. In the second scenario, the patient first educates himself, remotely interacts with health counselor or physician, then obtains a preliminary diagno- sis or knowledge about his/her condition, and last goes to a hospital for lab tests, confirmed diag- nosis, and treatment. In the more recent model, The number of users of conventional healthcare mainly comes from people or populations with disease conditions as prevention of disease and promotion of health programs are not effective or massively used. Telemedicine applications slowly grow in number of users, especially those in rural or underserved regions as they also relate to people with conditions that require a specialist attention. In contrast, Telehealth users are growing at a fast pace, as wellness programs are being more accepted and widely used. We expect the number of users of Telehealth applications to outnumber the number of users in conventional health service provision. Projected Trends • Conventional healthcare service provision will mainly be relevant for advanced diag- the individual is proactive to his/her condition and health, participates and engages in wellness programs and activities, monitors his/her wellness state, and in case of disease condition, does inter- consultation, and visits a healthcare professional and setting for diagnosis and intervention. Reco- very is performed at home. Figure 4. Healthcare technologies. nosis and treatment that require adequate equipment and resources. In this health service provision, the number of users compared to most of the population will be lower. • Telemedicine and teleconsultation servi- ces will be on the rise for coverage of the remote and underserved population, where access to expert consultation is limited. The number of clinical applications will be increased. • Telehealth and wellness applications, servi- ces and users will be on the rise, surpassing the number of users of conventional heal- thcare settings. The trend is to engage indi- vidual in wellness programs so the users are more aware of their health and participate in prevention of disease and promotion of
  • 11. 135 Millán et al. Analysis of Economic and Business Factors Influencing Disruptive Innovation in Telehealth health programs. The trend is to incorpo- rate wellness programs in schools, corpo- rate offices, gymnasiums, parks, malls and stores for accessibility, low cost and massive use. • From the technology point of view, we expect great development of communica- tion protocols, mobile health applications, Internet of Things IOTs applications, information highways, and integration of applications through common communi- cation interfaces. • Big Data analytics, clinical analytics, public health analytics will be on the rise for au- tomated decision making, coordination of services, and development of health pro- vision programs according to the needs of the population. Questions to Ask In order to introduce new ICT tools, models and concepts in Telehealth, the following questions should be initially asked • How can a ICTs impact the coverage and quality of service provided by public and private entities, as well as the cost effecti- veness, benefit and utility of the delivery of health services? • How can health promotion and prevention activities by Telehealth improve the health economy in Colombia? • Under what conditions and limitations does Telehealth have the potential to bene- fit the health economy? • What are the macroeconomic benefits and benefits of the provision of services and the establishment of health programs through Telehealth? • Which areas of Telehealth in the panorama of health services delivery in Colombia have a greater possibility of improving the health economy? Acknowledgement This research has been supported by the School of Health, Universidad Nacional Abierta y a Distan- cia UNAD, Bogotá, Colombia. Referencias 1. Ministerio de Proteccion Social, República de Colombia.. Ha- cia un Plan País en Telesalud. Junio 4 del 2009 2. Mushkin, S. “Hacia una definición de la economía de la sa- lud”, Lecturas de Economía No. 51. Diciembre de 1999 3. Edwards, R. T.. Paradigms and Research Programmes: is it time to move from health care economics to health econo- mics? Health Economics. 2001, 10: 635-649 4. Williams, A. Health economics: the cheerful face of the dis- mal science? In Health and Economics, Williams A (ed.). Macmillan Press: Basingstoke, 1987; 1–11. 5. Porter, M. E. What is Value in Healthcare? N Engl J Med 2010; 363: 2477-2481 6. Cooper R., and Jones, A. Supply and Demand in Health-Care Markets, Section 16.1 from the book Theory and Applications of Economics, 2012 7. Menachemi N., et al. Factors Affecting the Adoption of Tele- medicine—A Multiple Adopter Perspective. Journal of Medi- cal Systems. 2004, Vol. 28, No. 6 8. Henry Kaiser Family Foundation Snapshots: How Changes in Medical Technology Affect Health Care Costs. March 2, 2007. Obtained from http://kff.org/health-costs/issue-brief/ snapshots-how-changes-in-medical-technology-affect/ 9. Cutler, D. M. and McClellan, M. “Is Technological Change in Medicine Worth It?” Health Affairs 20(5) (September/October 2001): 11-29. 10. Espinosa K, Restrepo j, y Rodríguez S. Lecturas de Economía, 59 (julio-diciembre, 2003), pp. 7-53. Producción académica en Economía de la Salud en Colombia, 1980-2002. 11. Vo A., et. al. Benefits of Telemedicine in Remote Communi- ties & Use of Mobile and Wireless Platforms in Healthcare. UTMB Telemedicine and Center for Telehealth Research and Policy. n/d. 12. Fong B, et al. Telemedicine Technologies: Information Tech- nologies in Medicine and Telehealth. Wiley, 2010. 13. Kannisto K. A., et al. Use of Mobile Phone Text Message Re- minders in Health Care Services: A Narrative Literature Re- view. J Med Internet Res. 2014 Oct; 16(10): e222. 14. Hall A., et al. Mobile Text Messaging for Health: A Systematic Review of Reviews. Annu Rev Public Health. 2015, Mar 18; 36: 393–415.
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