Abhishek Ghara completed an industrial training at Gluconate Health Limited, a pharmaceutical manufacturing company in West Bengal. [1] The company was formed through the merger of two companies in 1990 and is wholly owned by the government of West Bengal. [2] Ghara thanks the managers and staff at the company for their cooperation and guidance during his training. [3] He provides details of the company's production, quality control, packaging, and other departments as well as the instruments used and manufacturing processes for tablets, capsules, and liquids.

1. SUBMITTED BY: - ABHISHEK GHARA
(B. PHARM, 3rd
YEAR)
ROLL NO – 17401913001
Registration no - 13174021001
NETAJI SUBHAS CHANDRA BOSE INSTITUTE OF
PHARMACY
TATLA, CHAKDAHA, NADIA, WEST BENGAL
PIN- 741222

2. CERTIFICATE GIVEN BY COMPANY

3. ACKNOWLEDGEMENT
I am thankful to the Quality Assurance Manager Mr. Sudip Ganguly of
Gluconate Health Limited because without his approval I could not join and
complete my training.
I am also thankful to Works Manager, Production Manager, Quality Control
Manager and all other Chemist and Workers for their generous co-operation.
I am greatly thankful to Dr. Arnab Samanta (Principal of NSCBIP) and Dr.
Sudipa Das (Assistant Professor of NSCBIP) for giving me a chance to perform the
industrial training.
Last but not least my special thanks to the most important persons of my
life, my Parents for their never ending support & blessings.

4. CONTENT
1. Company Profile (1)
2. Layout of Industry (2)
3. Organizational Structure (3)
4. List of Raw Material (4)
5. Production Department (5-15)
Instrument
Mfg. Process
6. Q.C. Department (16)
7. Packaging Department (17)
8. Store Department (18)
9. List of Product Name (Generic) (19)
10. Good Manufacturing Process (20)
11. Conclusion (21)

5. COMPANY PROFILE
Gluconate Health Ltd. factory Is situated in the Dumdum Cantonment,
Health Institute Road and the registered head office is 2, Durga Charan Doctor
Lane, Kolkata- 700014, West Bengal.
The 1st. Chief Minister of West Bengal and the great visionary Dr.Bidhan
Chandra Roy’s effort to discover anti malarial drug from ‘Chhatim’ tree (Astonia
Scolaris), culminated to the foundation of the pharmaceutical manufacturing
company Gluconate India Limited in 1933. Following this in 1936 some young
ambitious medical practitioners formed Indian Health Institute Ltd, to
manufacture Vaccine, Injections, Tablets, Capsules and liquids. Gluconate India
Limited and Indian Health Ph. Ltd. were merged and in 1990 Gluconate Health
Limited were formed on the principle of ‘having best of both’.
Since 1987 both these companies have been nationalized and presently
Gluconate Health Limited is a wholly owned enterprise under Government of
West Bengal, which contrary to the popular belief about government run
companies are likely to be unhealthy, GHL stands out proudly and have shown
steady growth and profit with promise to grow high in coming years. We have
always extended our active effort to ensure the success of any healthcare
program taken by the government at any level and our commitment towards this
are always on priority. We are a major player in the country in supplying essential
medicines at most affordable price to various government bodies. We have
achieved commendable success by supplying our high quality medicines to ensure
the success of “women and child development program” under UNDP.
We supply a large number of our products in high quantity to Govt. of
W.Bengal, Bihar, Jharkhand, Chhattisgarh, Tripura, Andhra Pradesh, PGI
Chandigarh, ICDS, various Government of India healthcare program and many
more reputed institutions.
1

6. LAYOUT OF INDUSTRY
2

7. ORGANIZATIONAL STRUCTURE
3

8. LIST OF RAW MATERIALS
TABLET PREPARATION
(For Azithromycin 500mg)
CAPSULE PREPARATION
(For Amoxycylin 250mg)
LIQUID PREPARATION
(For Metronidazole
Suspension 60ml)
1. Azithromycin
powder
2. Sodium Lauryl
Sulphate
3. Sodium Starch
4. Lactose
5. Talcom Powder
6. MCC 102
7. Magnesium Stearate
8. Aerosil
1. Amoxycylin powder
2. Sodium Starch
Glycolate
3. Aerosil
4. Talcom powder
1. Metronidazole
2. Sodium Benzoate
3. Sodium Methyl &
propyl Paraben
4. Sorbitol
5. Aspartame
6. Guargum
7. American ice cream
soda
8. Sodium Saccharine
9. Aerosil
10.Citric Acid
11.CMC Solution
12.Disodium EDTA
4

9. TABLET DEPARTMENT
INSTRUMENT:
 Paste Cattle
 Rapid Mixer Granulator
 Fluidised Bed Dryer
5

10.  Octagonal Blender
 Sieving Machine
 Multimill
6

11.  Rotary Punching Machine
 Coating Machine (Unicota)
7

12. TABLET MANUFACTURING PROCESS:
8

13. CAPSULE DEPARTMENT
INSTRUMENT:
 Double Cone Blender
 Casule Filling and Sealing Machine
9

14.  Capsule Polishing Machine
MANUFACTURING PROCESS OF HARD GELATIN CAPSULE:
10

15. LIQUID DEPARTMENT
INSTRUMENT:
 Charging Van
11

16.  Reserve Van
 24 Station Rotary Washing Machine
 8F Bottle Filling Machine
12

17.  8F Capping Machine
 Bottle Checking Machine
13

18.  Bottle Labelling Machine
MANUFACTURING PROCESS OF LIQUID PREPARATION
14

19.  After sealing and labelling the bottle will be packed in large cartoon box.
100 bottles in one box are packed, sealed and stored for marketing
requirements.
15

20. QUALITY CONTROL DEPARTMENT
INSTRUMENT AVAILABLE:
1. PH
meter
2. Conductivity meter
3. Leak test apparatus
4. Polarimeter
5. Fribilator USP
6. Melting point apparatus
7. Hot air oven
8. DV-E viscometer
9. Mechanical stirrer
10.Dissolution tester USP
11.Media preparator
12.Digital weighing machine
13.Disintegration test appratus
14.Spectophotometric meter
QUALITY TEST (Norfloxacin tablet):
TITRATION (NON-AQUEOUS):
Tablet triturate 50ml Glacial acetic acid Produce raddish colour
Add Perchloric acid (0.1M) dropwise Produce ash colour.
DISSOLUTION TEST:
 Six tablets give in dissolution test apparatus for 30 minutes at 50
rpm.
 Filter the tablet solution in six measuring cylinder (in each 20ml).
 Take 1ml tablet solution in each and transfer in different volumetric
flask (six) and fillup the volume upto 100ml by acetic buffer.
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21. PACKAGING
BLISTER PACKING
(For Tablets and Capsules)
It is formed in PVC sheet and tablets are packed using Aluminium foil on opposite
side. Sealed in normal Blister pack machine is used.
 Formation Roller
 Formation Heater
 Hopper
 Bowl Dish
 Channel
 Printer
 Cutter
Then the strips are checked and collected and 10 tablet strips are packed into a
small box and then 100 small boxes are packed in a large box and sealed for
marketing requirements.
A strip contains 10 or 20 tablets depending upon the size & shape of the tablet.
h
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22. STORE
In the store of the industry raw materials are stored for the manufacturing and
production. It has four zones, first quqrantine for primary uploading point, second
is the red zone where rejected materials are stored, third is the green zone where
quality control test passed materials are stored and the last one yellow zone
where primary rejected materials are stored.
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23. LIST OF PRODUCT
TABLETS
SL. NO. NAME OF THE PRODUCT PKG DESCRIPTION
1
2
3
4
5
6
Azethromycin 500mg
Norfloxacin 400mg
Paracetamol 500mg
Ibuprofen 200mg + 400mg
Metronidazole 200mg +
400mg
Ranitidine 150mg
10*10’s
10*10’s
10*10’s
10*10’s
10*10’s
10*10’s
Anti-biotic
Anti-microbial
Antipyretic
Anti Inflammatory
Anti Amoebic
Anti ulcer
CAPSULES
SL. NO. NAME OF THE PRODUCT PKG DESCRIPTION
1
2
3
4
Amoxycillin 250mg
Ciprofloxacin 250mg + 500mg
Ampicillin + Cloxacillin 250mg
Rifampicin 450mg
10*10’s
10*10’s
10*10’s
10*10’s
Antibiotic
Anti-microbial
Antibiotic
Anti-T.B.
LIQUIDS
SL. NO. NAME OF THE PRODUCT PKG DESCRIPTION
1
2
3
4
5
6
7
8
9
Metronidazole suspension
Paracetamol syrup
Syrup Molar Sodium Lactate
Gention Violet
Erythromycin Suspension
Alkacitron
Glucorex
Zymoton
B com T
60ml
60ml
450ml
100ml
60ml
100ml
100ml
100ml
200ml
Amoebicidal
Antipyretic
Oxidant
Dermatological Agent
Anti-microbial Agent
Urinary Infection
Expectorant
Digestive enzyme secretion
Vit B
19

24. CONCLUSION
It has been a pleasure to undergo training GLUCONATE HEALTH LTD organization;
GLUCONATE HEALTH LTD is real boost for the economic development in the
countries, India. Responsible authorities should be more flexible in promotion of
such organization creating employment and effective utilization of locally
available resources.
Observing the various instruments used in different sections give me the much
needed exposure to the pharma industry. All these aspects are really learnable
area where one can gather a lot of knowledge.
The adoption and maintainance of the quality policy are readily astonishing and
the purpose is very clear, effective and praise worthy.
Our training programmed was assisted by the helping hands of the employees of
this organization is thus a fullfillment of our objectives and the learning will
obviously be an asset for us in the long future.
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