The document summarizes the synthesis of new triazenoazaindole compounds with potential antitumor activity. It introduces that new chemotherapeutic agents are still needed to treat cancer. It describes that a new class of compounds bearing a triazenoazaindole scaffold were synthesized with the aim of identifying new antiproliferative agents. The antiproliferative activity of the compounds was evaluated in five human tumor cell lines and results were expressed as GI50 values, with dacarbazine as a reference, showing the compounds have cytotoxic potential and warrant further investigation.