Dr. Schally is a world renowned endocrinologist and I have had the privilege of collaborating with him on several projects focused on growth hormone signaling and cognitive aging. We are currently investigating how modulating growth hormone receptor activity impacts learning, memory and neurogenesis in the hippocampus of young and aged mice. I am responsible for designing and conducting the behavioral experiments, analyzing the results and assisting in writing manuscripts. This work has the potential to identify new therapeutic targets for cognitive decline.

1. Kristina K Aenlle, PhD
3047 Hibiscus St •Miami FL 33133 • (305) 968-2970
kristinaaenlle@gmail.com
Highly motivated, meticulous and team-oriented scientist with 15 years of expertise in Neuroscience, Neurology,
Neuroendocrinology, Molecular Biology, Stem Cell Biology and Oncology; Excellent leadership and presentation skills
characterized by strong decision making abilities. Comfortable working with people of all levels with a proven track record
in developing successful growth strategies and the professional evolution of team members.
SCIENTIFIC EXPERTISE
• Neuroscience /Neuroendocrinology
• Women's Health
• Adult Stem Cell Therapeutics
• Project Management
• Research Study Design
• Public Speaking
• Clinical Trial Implementation
Regulation and Guidelines
• Scientific Writing
PROFESISONAL EXPERIENCE
Sr. Research Scientist/Post-Doctoral Fellow 2009-Present
Department of Veterans Affairs: Geriatric Research, Education and Clinical Center Miami, FL
Lead scientist in aging, adult stem cell,endocrinology and HGF mechanisms of osteogenic differentiation.
• Cultivate collaborative relationships with Key Opinion Leaders (KOLs), clinicians, and other researchers to
accomplish project goals
• Designed and implemented research projects focused on the role of Hepatocyte Growth Factor in human mesenchymal
stem cells osteogenic differentiation and bone health and repair.
• Wrote and published 4 peer reviewed scientific articles
• Presented scientific presentations at National and local scientific meetings
• Served as a public speaker at Annual Endocrine Society Meeting
• Supervised and mentored graduate and undergraduate students
• Managed and trained young scientists
• Wrote and Managed NIH/Merit Grants
• Chair and Member of Federal Regulatory Boards and Committees
Doctor of Philosophy/Pre-doctoral Fellow 2003- 2009
University of Florida: Department of Neuroscience Gainesville, FL
Thesis: ESTROGEN TREATMENT IN THE HIPPOCAMPUS: ANALYSIS OF GENE EXPRESSION AND COGNITIVE FUNCTION IN THE AGING
FEMALE MOUSE
• Awarded NIA Training Fellowship
• Designed and implemented research projects focused on determine the role of estrogen during cognitive aging
• Wrote and published 3 peer reviewed scientific articles on the effects of estrogen on cognitive aging
• Wrote and published book chapter in a leading Neuroscience textbook
• Presented scientific presentations at National and local scientific meetings; including Society for Neuroscience
• Supervised and mentored undergraduate students
Certificate in Gerontology 2006-2008
University of Florida : Institute on Aging Gainesville, FL
• Studied the Clinical aspects of Aging Research
• Studied the Regulations and Guidelines of Clinical Research
Bachelor of Science; Psychology 1996- 2001
Michigan State University East Lansing, MI
• Created a Brain atlas for use in medical school settings
• Assisted in neurochemical experiments of puberty and the effects on behavior

2. SELECT PUBLICATIONS/PRESENTATIONS
Journal Publications
Curtis KM, Aenlle KK, Frisch RN, Howard GA. (2015) TAp63γ and ΔNp63β Promote Osteoblastic Differentiation of
Human Mesenchymal Stem Cells: Regulation by Vitamin D3 Metabolites. PLOS ONE 10(4):e0123642.
Aenlle KK, Curtis KM, Roos BA, Howard GA. (2014) Hepatocyte growth factor and p38 promote osteogenic differentiation
of human mesenchymal stem cells. Molecular Endocrinology 28(5):722-30.
Curtis KM, Aenlle KK, Roos BA, Howard GA. (2014) 24,25-dihydroxyvitamin D modulates the osteogenic maturation of
human mesenchymal stem cells. Molecular Endocrinology 28(5):644-58.
Han X, Aenlle KK, Bean LA, Rani A, Semple-Rowland SL, Kumar A, Foster TC. (2013) Role of estrogen receptor alpha
and beta in preserving hippocampal function during aging. Journal of Neuroscience 33(6):2671-83.
Chen K, Aenlle KK, Curtis KM, Roos B., Howard GA. (2012) Hepatocyte growth factor (HGF) and 1,25-dihydroxyvitamin
D together stimulate human bone marrow-derived stem cells toward the osteogenic phenotype by HGF-induced up-regulation
of VDR. Bone 51:69-77.
Aenlle KK, Foster TC. (2010) Aging alters the expression of genes for neuroprotection and synaptic function following acute
estradiol treatment. Hippocampus 20(9):1047-60.
Aenlle KK, Kumar A, Cui L, Jackson TC, Foster TC. (2009) Estrogen effects on cognition and hippocampal transcription in
middle-aged mice. Neurobiol Aging 30(6):932-45.
Marino L, Sudheimer KD, Murphy TL, Davis KK, Pabst DA, McLellan WA, Rilling JK, Johnson JI. (2001) Anatomy and
three-dimensional reconstructions of the brain of a bottlenose dolphin (Tursiops truncatus) from magnetic resonance images.
Anat Rec 264:397-414.
Book Chapter
Aenlle KK, Foster TC. Gene expression and signal transduction cascades mediating estrogen effects on memory. Genomics,
Proteomics and the Nervous System. Advances in Neurobiology. 1st
Edition 2011, pp 161-176.
Presentations/Published Abstracts
Curtis KM, Aenlle KK, Frisch RN, Howard GA. Vitamin D3 Metabolites Regulate the Activities of TAp63γ and ΔNp63β in
Promoting Osteoblastic Differentiation of Human Mesenchymal Stem Cells: Regulation by Vitamin D3 Metabolites. 18th
Workshop on Vitamin D, April 2015, Delft, Netherlands. (Poster presentation). Won Best Overall Poster.
Curtis KM, Aenlle KK, Frisch RN, Howard GA. TAp63γand ΔNp63β Promote Osteoblastic Differentiation of Human
Mesenchymal Stem Cells: Regulation by Vitamin D3 Metabolites. The Endocrine Society National Meeting, March 2015,
San Diego CA. (Poster presentation).
Aenle KK, Curtis KM, Chen K, Howard GA. Hepatocyte Growth Factor Activation of p38 in human Mesenchymal Stem
Cells, Department of Veterans Affairs Research Week, May 2013 Miami FL (Poster Presentation)
Aenlle KK, Curtis KM, Chen K, Roos BA, Howard GA. Hepatocyte Growth Factor Promotes Osteogenic Differentiation
of Human Mesenchymal Stem Cells through the p38 Pathway. University of Miami Miller School of Medicine; Annual
Postdoctoral Fellows Research Day. Sept. 2012, Miami FL. (Poster Presentation).
Aenlle KK, Curtis KM, Chen K, Roos BA, Howard GA. Hepatocyte Growth Factor Promotes Osteogenic Differentiation of
Human Mesenchymal Stem Cells Through the p38 Pathway, The Endocrine Society National Meeting, June 2012, Houston,
TX (Oral Presentation)
Curtis KM, Aenlle KK, Chen K, Roos BA, Howard GA. 24,25-dihydroxyvitamin D Promotes the Osteogenic Maturation of

3. Human Mesenchymal Stem Cells Through the Regulation of p63. The Endocrine Society National Meeting, June 2012,
Houston TX. (Poster Presentation).
Howard GA, Curtis KM, Aenlle KK, Chen K, Roos BA. Regulating human mesenchymal stem cells for osteogenic tissue
repair by p63 and p38 isoforms. Int’l Soc for Cellular Therapy, June 2012, Seattle, WA (Oral presentation)
Howard GA, Curtis KM, Aenlle KK, Chen K, Roos BA: Human mesenchymal stem cells for repair of the aging skeleton:
Regulation by isoforms of p63 and p38. Gerontological Society of America – 65th
Annual Scientific Meeting, November 2012,
San Diego, CA (Oral Presentation)
Aenlle KK, Foster TC. Time Course of Estrogen Treatment in Middle-Aged Mice, Society for Neuroscience, November
2006, Atlanta, GA (Poster Presentation)
Aenlle KK, Kumar A, Foster TC. Effects of Cyclic Estrogen Treatment on Memory and Transcription in Middle Aged Mice,
Society for Neuroscience, November 2005, Washington, DC. (Poster Presentation)
Johnson JI, Sudheimer KD, Davis KK., Winn BM. Brain Atlas of the Sheep on the Internet for Courses in Neurobiology,
Society for Integrated and Comparative Biology, January 2001 Chicago, IL (Poster Presentation)
PROFESSIONAL ACTIVITIES AND HONORS
Award Recipient, National Institute on Aging: Training in Aging Fellowship, FL, 2006-2008
Society Member, Society for Neuroscience, 2004-
Society Member, The Endocrine Society, 2012-
LEADERSHIP
Miami VA Healthcare Systems:
IUACUC Chair 2015-Present
IUACUC Subcommittee 2013-Present:
Biosafety Subcommittee 2014-Present
Scientific Review Subcommittee 2014-Present
Community Involvement:
Brain Awareness Week Organizer 2013-
Head Start Community Policy Member 2012-2013
Head Start Community Member 2013-2014
COLLABORATIVE PROJECTS
2012-Present
Andrew V. Schally, Ph.D., Distinguished Medical Research Scientist of the Department of Veterans Affairs; Head of
The Endocrine, Polypeptide and Cancer Institute, Miami VA Medical Center; Distinguished Professor of Pathology,
Professor of Hematology/Oncology
Recipient: Nobel Prize in Physiology or Medicine, 1977
Focus & Contribution: To determine the role of Growth Hormone Receptor antagonist on cognitive function in naïve and
cognitively impaired mice