ADENOMYOSIS
 DEFINITION
ETIOPATHOGENESIS
CLINICAL FEATURES
GROSS FINDINGS
HISTOLOGICAL FINDINGS
MRI FINDINGS
MANAGEMENT
DEFINITION
 Presence of endometrial islands within the uterine
wall i.e., myometrium
 Usually endometrial glands are present only in
endometrial layer of uterus ,which gets sloughed
off regularly during menses
 But in this condition there occurs signifying down
growth of endometrial tissues into the
myometrium
ETIOPATHOGENESIS
 Elderly women aged above 40
 Younger women are also susceptible
 No clear pathogenesis .
 Believed as an endometrial tissue down
growth
 ASSOCIATIONS:
• Uterine fibromyomas
• Pelvic endometriosis
• Endometrial carcinomas
CLINICAL FEATURES
 Present with menorrhagia & progressively
increasing dysmenorrhea
 Pelvic discomfort, backache, dyspareunia
 Painful symmetrical enlargement of uterus
suggests adenomyosis following investigations
 Uterus size- resembles 3 month pregnancy
 Uterus may be symmetrically or asymmetrically
enlarged
 MRI is superior to USG for diagnosing
adenomyosis
GROSS FINDINGS
GROSS FINDINDS (CONTD…)
 Uterus appears symmetrically enlarged
resembling not more than 14 weeks size
 Asymetrical enlargement of uterus may also be
seen in some cases which may confused with
myoma
 Affected area shows peculiar and diffuse
involvement of myometrium
 Posterior wall- dark hemorrhagic areas in b/w
normal areas
 Cross section shows localized nodular
enlargement
 Enlargement-due to hyperplasia of smooth
HISTOLOGY
 ENDOMETRIAL ISLAND PRESENT
DEEP WITHIN
STROMA(MYOMETRIUM)
MRI FINDINGS
SYMMETRICAL
ENLARGEMENT
ASYMMETRICAL
ENLARGEMENT
MANAGEMENT
 HYSTERECTOMY with or without salpingo-
oopherectomy - if women aged 40 years
above and indicated
 If not interested or if she is young
• NSAIDs (medical)
• GnRH(hormonal)
• Mirena IUCD
• TCRE(trans cervical resection
of endometrium)
THANK YOU

Adenomyosis

  • 1.
  • 2.
     DEFINITION ETIOPATHOGENESIS CLINICAL FEATURES GROSSFINDINGS HISTOLOGICAL FINDINGS MRI FINDINGS MANAGEMENT
  • 3.
    DEFINITION  Presence ofendometrial islands within the uterine wall i.e., myometrium  Usually endometrial glands are present only in endometrial layer of uterus ,which gets sloughed off regularly during menses  But in this condition there occurs signifying down growth of endometrial tissues into the myometrium
  • 4.
    ETIOPATHOGENESIS  Elderly womenaged above 40  Younger women are also susceptible  No clear pathogenesis .  Believed as an endometrial tissue down growth  ASSOCIATIONS: • Uterine fibromyomas • Pelvic endometriosis • Endometrial carcinomas
  • 5.
    CLINICAL FEATURES  Presentwith menorrhagia & progressively increasing dysmenorrhea  Pelvic discomfort, backache, dyspareunia  Painful symmetrical enlargement of uterus suggests adenomyosis following investigations  Uterus size- resembles 3 month pregnancy  Uterus may be symmetrically or asymmetrically enlarged  MRI is superior to USG for diagnosing adenomyosis
  • 6.
  • 7.
    GROSS FINDINDS (CONTD…) Uterus appears symmetrically enlarged resembling not more than 14 weeks size  Asymetrical enlargement of uterus may also be seen in some cases which may confused with myoma  Affected area shows peculiar and diffuse involvement of myometrium  Posterior wall- dark hemorrhagic areas in b/w normal areas  Cross section shows localized nodular enlargement  Enlargement-due to hyperplasia of smooth
  • 8.
    HISTOLOGY  ENDOMETRIAL ISLANDPRESENT DEEP WITHIN STROMA(MYOMETRIUM)
  • 9.
  • 10.
    MANAGEMENT  HYSTERECTOMY withor without salpingo- oopherectomy - if women aged 40 years above and indicated  If not interested or if she is young • NSAIDs (medical) • GnRH(hormonal) • Mirena IUCD • TCRE(trans cervical resection of endometrium)
  • 11.