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Acute Renal Failure And Sepsis

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shivabirdi
shivabirdi

This document discusses acute renal failure in patients with sepsis. It defines sepsis and the RIFLE classification system for acute renal failure. It then covers the pathophysiology of how sepsis can lead to acute renal failure, including arterial vasodilation, hemodynamics, hormones, and effects on Starling forces. Early fluid resuscitation, glucose control, glucocorticoids, and renal replacement therapy are presented as beneficial interventions for patients with sepsis and acute renal failure based on clinical studies.

Economy & FinanceHealth & Medicine
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Acute Renal Failure and Sepsis Michael Fernando M.D. PGY-3 Cleveland Clinic July 18, 2007
Clinical Definition of Sepsis
RIFLE classification of Acute Renal Failure ,[object Object],[object Object],[object Object],[object Object],[object Object]
Occurrence of Acute Renal Failure in Sepsis
Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hemodynamics and Hormones ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathophysiology
Pathophysiology II ,[object Object],[object Object],[object Object],[object Object]
Importance of Vasopressin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vasopressin and GFR ,[object Object],[object Object],[object Object],[object Object]
Effects of Systemic Arterial Vasodilation on Starling forces ,[object Object],[object Object],[object Object]
Effects of systemic arterial vasodilatation (cont.’d) ,[object Object],[object Object],[object Object]
Excessive fluid administration in the setting of Sepsis and ARF ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Experimental models of Sepsis induced ARF ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Benefits of Early Fluid Resuscitation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Glucose Control ,[object Object],[object Object]
Benefits Glucorticoids ,[object Object],[object Object],[object Object]
 
Renal Replacement Therapy ,[object Object],[object Object]
Peak Concentration Hypothesis
Renal Replacement Therapy ,[object Object],[object Object]
Conclusions ,[object Object],[object Object],[object Object]

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