hemolytic disease of new born is an aquire alla immune hemolytic anemia characterize by production extravascular destruction of RBC within the spleen of new born baby resulting anemia, positive coomb,s test
Among blood group incompatibility more than 95% are caused by ABO and Rh blood type. Remaining less than 5% are caused by Duffy, Lewis , Kidd and other minor blood group.
ABO incompatibility are more common, less severe but Rh incompatibility are less common, more severe.
This presentation describes in detail about managing Rh negative pregnancy- to identify and manage Rh non-isommunized and Rh isoimmunized pregnancies, with recent advances
Rh Incompatibility I Hemolytic Disease of the NewbornSwatilekha Das
Rh Incompatibility I Hemolytic Disease of the Newborn-
Hi All,
I am Swatilekha Das, B.Sc, M.Sc Nurse and working as Assistant Professor of Nursing in a Nursing college. I worked as Clinical Instructor, nursing educator, nursing trainer, Nursing Tutor at hospitals, nursing schools and colleges.
ABOUT THIS ppt-
In this ppt I discussed about definition of rh incompatibility, cause, pathophysiology, diagnostic tests, treatment and screening and prevention of Rh incompatibility.
To know about it check the ppt till end.
I hope you enjoy this ppt and if you do then please click on the like button and share the with your friends too . Don't Forget to follow to see more such ppt. Thank you for checking the ppt.
@All Rights Reserved..
Majority of fetal deaths occur in the antepartum period.
There is progressive decline in maternal deaths all over the world. Currently more interest is focused to evaluate the fetal health. The primary objective of antenatal assessment is to avoid fetal death.
hemolytic disease of new born is an aquire alla immune hemolytic anemia characterize by production extravascular destruction of RBC within the spleen of new born baby resulting anemia, positive coomb,s test
Among blood group incompatibility more than 95% are caused by ABO and Rh blood type. Remaining less than 5% are caused by Duffy, Lewis , Kidd and other minor blood group.
ABO incompatibility are more common, less severe but Rh incompatibility are less common, more severe.
This presentation describes in detail about managing Rh negative pregnancy- to identify and manage Rh non-isommunized and Rh isoimmunized pregnancies, with recent advances
Rh Incompatibility I Hemolytic Disease of the NewbornSwatilekha Das
Rh Incompatibility I Hemolytic Disease of the Newborn-
Hi All,
I am Swatilekha Das, B.Sc, M.Sc Nurse and working as Assistant Professor of Nursing in a Nursing college. I worked as Clinical Instructor, nursing educator, nursing trainer, Nursing Tutor at hospitals, nursing schools and colleges.
ABOUT THIS ppt-
In this ppt I discussed about definition of rh incompatibility, cause, pathophysiology, diagnostic tests, treatment and screening and prevention of Rh incompatibility.
To know about it check the ppt till end.
I hope you enjoy this ppt and if you do then please click on the like button and share the with your friends too . Don't Forget to follow to see more such ppt. Thank you for checking the ppt.
@All Rights Reserved..
Majority of fetal deaths occur in the antepartum period.
There is progressive decline in maternal deaths all over the world. Currently more interest is focused to evaluate the fetal health. The primary objective of antenatal assessment is to avoid fetal death.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
3. INTRODUCTION
ABO-Hemolytic disease of newborn
25% of pregnancies
HDN develops only in 1/10 such offsprings
O group mother and A/B group fetus
Female>male
OA>OB
Cause-reaction of maternal anti-A/B to antigen present
on RBC of fetus or newborn
IgG antibodies cross the placenta
4. BLOOD TYPES
ABO system in 1990
A,B,AB,O
Central principle is ANTIGENS
Isoantibodies against isoantigens
Important for transfusion
6. ABO on 9q34 -glycosyltransferase
A- N-acetyl galactosamine
B- galactose
H on 19
H antigen-precursor
Antigens contained in food,bacteria and vaccines
7.
8. MODERATING FACTORS
Mild nature and low incidence of ABO-HDN accounts
for
low antigenicity of AB factors
wide distribution
fewer antigen sites on preterm RBC
9. DIFF B/N ABO & RH
INCOMPATIBILTIES
May occur in first born
Increasing frequency of disease in subsequent
pregnancies is generally not present
The subsequent babies may be more effected or less
effected or even spared
10. HS AND ABO-HDN
Increased osmotic fragility, autohemolysis,
splenomegaly in both
But autohemolysis is not corrected by glucose as in HS
Family history,long-term course,MCHC differentiate HS
from ABO-HDN
11. DIAGNOSIS(suspected)
Antenatally –
Past history of ABO-HDN in previous sibling
Titer of anti-A/anti-B in mother is >1:64
Postnatally –
Early onset of jaundice <24hrs
A/B group baby of O mother
Mild splenomegaly
Anemia – usually absent
12. DIAGNOSIS(laboratory)
Serum bilirubin
Reticulocytosis
Spherocytosis
Fragility of RBC
Confirmation of antibodies-eluted serum
Direct coomb’s test
Maternal IgG antibodies in ADCC assay
Detection of antigen density on RBC
High titres of anti-A/B hemolysins-in maternal serum
13. Start intensive phototherapy if bilirubin exceeds
10mg/dl at 12hrs
12mg/dl at 18hrs
14mg/dl at 24hrs
15mg/dl at any time
Exchange transfusion-if it reaches 20mg/dl
MANAGEMENT
16. SUMMARY
INCIDENCE
O group mother and A/B group fetus
Co-dominant inheritance
HS and ABO-HDN
Diagnosis
Management –phototherapy and exchange transfusion
17. REFERENCES
Manual of neonatal care-CLOHERTY
Care of new born-MEHERBAN SINGH
HARRISON’S principles of internal medicine