This document provides a review of a proposed three-in-one air cooling system that uses evaporative cooling, desiccant cooling, and a heat and mass exchanger (HMX) to cool air without increasing humidity. The system combines direct and indirect evaporative cooling for higher effectiveness and lower energy consumption compared to vapor compression air conditioning systems. It also uses a desiccant wheel to control humidity. The HMX allows indirect evaporative cooling of a primary air stream through a wet secondary air stream to lower the temperature without increasing moisture content. This innovative three-in-one system could replace vapor compression systems to reduce electrical energy usage and emissions from air conditioning.