Art and science in literary work makes an essence for the post-modern era reading with an impact. In this research paper, the study takes place with Alan Moore’s writing of Art and Science with selected novels as “V for Vendetta”, “Watchman” and “Swamp Things.” In seeking to control their constituents, the fascist government ruling Moore and Lloyd’s vision of England has eradicated many of the arts from society. In the select novels deals with how the use if Sci-fi changed the phenomena of reading of literature with pop art. The extent of this artistic suppression is evidenced in V’s Shadow Gallery, where he seeks to preserve much of the art that has been removed from society. Much of the science in V for Vendetta is eerily similar to that of the Nazis during World War II, using members of “resettlement camps” as subjects for inhumane experiments and this can be very well presented in the paper with the theory of New Historicism. In comics/graphic novels as resources for postmodern science education by focusing on representations of modern scientific concepts in Watchmen's narrative themes and the unique capability of the sequential art medium to represent key concepts in postmodern science. And Swamp Things can change the perception of how culture and science can happen drastically to the humanity. Though the art and science of wring and creates a kind of genre that can take writing of this with visualize technique as well.