This document discusses various conditions in children that can lead to bowel dysfunction, including spinal cord injuries, sacral agenesis, necrotizing enterocolitis (NEC), Ehlers-Danlos syndromes (EDS), and spina bifida. It provides details on the symptoms and impacts of each condition, such as neurogenic bowel from spinal cord injuries depending on the level of injury. It also discusses challenges children face in managing bowel issues, like negative quality of life impacts and potential lack of treatment due to lack of knowledge.
Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD). Spina bifida can happen anywhere along the spine if the neural tube does not close all the way.
Spina Bifida Birth Defects: Possible Causes of Congenital Injuries Exploredlawsuitlegal
What causes spina bifida? The following examines the data for and against an antidepressant (SSRI) causal link for congenital spina bifida and other malformations in newborns. We gathered some of the important research studies and shared their findings.
Allegations have been made that a number of developmental problems and congenital injuries are caused by prenatal SSRI exposure. Are these drugs dangerous or is it just tort attorneys looking for big pockets.
Our spina bifida lawyers are investigating claims from families whose babies were born with complications. If your child was exposed in utero to an anti-depressant, and was born with a congenital defect, visit our site and share what happened immediately to get more information on possible lawsuit options which may be available.
1. pedologic anatomy with special emphasis on its appliedNivedita Jain
Pedologic Anatomy with special emphasis on it's applied aspect is a basic science seminar which is important to all Pediatric Dentists and BDS students both.
Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD). Spina bifida can happen anywhere along the spine if the neural tube does not close all the way.
Spina Bifida Birth Defects: Possible Causes of Congenital Injuries Exploredlawsuitlegal
What causes spina bifida? The following examines the data for and against an antidepressant (SSRI) causal link for congenital spina bifida and other malformations in newborns. We gathered some of the important research studies and shared their findings.
Allegations have been made that a number of developmental problems and congenital injuries are caused by prenatal SSRI exposure. Are these drugs dangerous or is it just tort attorneys looking for big pockets.
Our spina bifida lawyers are investigating claims from families whose babies were born with complications. If your child was exposed in utero to an anti-depressant, and was born with a congenital defect, visit our site and share what happened immediately to get more information on possible lawsuit options which may be available.
1. pedologic anatomy with special emphasis on its appliedNivedita Jain
Pedologic Anatomy with special emphasis on it's applied aspect is a basic science seminar which is important to all Pediatric Dentists and BDS students both.
Spina bifida is a birth disorder that involves the incomplete development of the spine. In the first month of pregnancy, a special set of cells forms the “neural tube;” the top of the tube becomes the brain, and the remainder becomes the spinal cord and structures around it. In spina bifida, the neural tube doesn’t close completely and some of the bones of the spine do not close in the back. This can result in an opening anywhere along the spine and may cause damage to the spinal cord and nerves.There are four types of spina bifida: occulta, closed neural tube defects, meningocele, and myelomeningocele. The symptoms of spina bifida vary from person to person, depending on the type and level of involvement. Most cases are mild and do not require special treatment. The more serious cases involve nerve damage.
Occulta is the mildest and most common form in which one or more bones of the spinal column (vertebrae) are malformed. The name “occulta,” which means “hidden,” indicates that a layer of skin covers the opening in the bones of the spine. It usually shows no symptoms and is often found by accident on an x-ray or similar test.
Closed neural tube defects are a diverse group of disorders in which the spine may have malformations of fat, bone, or the membranes (the meninges) that cover the spinal cord. Many of these neural tube defects require surgery in childhood. People with this type of spina bifida may have weakness of the legs and trouble with bowel and bladder control. These issues may change or progress as children grow. It is important to have close communication with doctors to minimize these changes as much as possible.
Meningocele occurs when the meninges protrude through the spine and cause a sac of spinal fluid on the back. This fluid is typically only around the brain and spine, but a problem with the bony covering over the spine allows it to poke out. The malformation contains no nerves and may or may not be covered by a layer of skin. Individuals with meningocele may have minor symptoms.Myelomeningocele is the most severe form of spina bifida. A portion of the spinal cord or nerves are exposed in a sac through an opening in the spine that may or may not be covered by the meninges. The opening can be closed surgically while the baby is in utero or shortly after the baby is born. Most people with myelomeningocele experience changes in brain structure, leg weakness, and bladder and bowel dysfunction.
Myelomeningocele is often called a "snowflake condition" because no two people with the condition are the same. Typically, if the opening in the spine is lower down the back, the person will experience less symptoms. People with myelomeningocele require close follow-up with physicians throughout their childhood and lifespan to maximize their function and prevent complications like kidney failure.Complications of spina bifida may include:
Abnormal sensation or paralysis, which mostly occurs with closed neural tube defects and myelomenin
MYELOMENINGOCELE copy.pptx a slide describing the conditionAjisafeZainab
Myelomeningocele is a disorder of the nervous system particularly the spine and spinal cord, before we go further in this presentation there are some terms to know to aid understanding.
➢Neural tube; The neural tube forms the early brain and spine, As development progresses, the top of the neural tube becomes the brain, and the rest of the tube becomes the spinal cord. An NTD happens when this tube doesn't close completely somewhere along its length. Neural tube closure is completed 28 days (four weeks) from conception.
➢Alpha fetoprotein; AFP is a protein that the liver makes when its cells are growing and dividing to make new cells. AFP is normally high in unborn babies. After birth, AFP levels drop very low. Healthy children and adults who aren't pregnant have very little AFP in their blood. Maternal AFP serum level is used to screen for Down syndrome, neural tube defects, and other chromosomal abnormalities.
➢Spinal bifida; Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD).
Nursing management of myelomeningocele
Types of spinal Bifida
Pathophysiology of myelomeningocele
My name is Dahianara Moran and I believe being the parent of a child with Spina Bifida is like having a sixth sense, something like a Super Mom. We learn quickly how to defend our little ones from the awkward moments, but most important, we come to enjoy the little things, value our moments, and commit to change the way the world defines “Disability”.
Spina bifida is a birth defect that occurs when the spine and spinal cord don't form properly. It falls under the broader category of NTD (Neural Tube Defects).
Spina bifida is a birth disorder that involves the incomplete development of the spine. In the first month of pregnancy, a special set of cells forms the “neural tube;” the top of the tube becomes the brain, and the remainder becomes the spinal cord and structures around it. In spina bifida, the neural tube doesn’t close completely and some of the bones of the spine do not close in the back. This can result in an opening anywhere along the spine and may cause damage to the spinal cord and nerves.There are four types of spina bifida: occulta, closed neural tube defects, meningocele, and myelomeningocele. The symptoms of spina bifida vary from person to person, depending on the type and level of involvement. Most cases are mild and do not require special treatment. The more serious cases involve nerve damage.
Occulta is the mildest and most common form in which one or more bones of the spinal column (vertebrae) are malformed. The name “occulta,” which means “hidden,” indicates that a layer of skin covers the opening in the bones of the spine. It usually shows no symptoms and is often found by accident on an x-ray or similar test.
Closed neural tube defects are a diverse group of disorders in which the spine may have malformations of fat, bone, or the membranes (the meninges) that cover the spinal cord. Many of these neural tube defects require surgery in childhood. People with this type of spina bifida may have weakness of the legs and trouble with bowel and bladder control. These issues may change or progress as children grow. It is important to have close communication with doctors to minimize these changes as much as possible.
Meningocele occurs when the meninges protrude through the spine and cause a sac of spinal fluid on the back. This fluid is typically only around the brain and spine, but a problem with the bony covering over the spine allows it to poke out. The malformation contains no nerves and may or may not be covered by a layer of skin. Individuals with meningocele may have minor symptoms.Myelomeningocele is the most severe form of spina bifida. A portion of the spinal cord or nerves are exposed in a sac through an opening in the spine that may or may not be covered by the meninges. The opening can be closed surgically while the baby is in utero or shortly after the baby is born. Most people with myelomeningocele experience changes in brain structure, leg weakness, and bladder and bowel dysfunction.
Myelomeningocele is often called a "snowflake condition" because no two people with the condition are the same. Typically, if the opening in the spine is lower down the back, the person will experience less symptoms. People with myelomeningocele require close follow-up with physicians throughout their childhood and lifespan to maximize their function and prevent complications like kidney failure.Complications of spina bifida may include:
Abnormal sensation or paralysis, which mostly occurs with closed neural tube defects and myelomenin
MYELOMENINGOCELE copy.pptx a slide describing the conditionAjisafeZainab
Myelomeningocele is a disorder of the nervous system particularly the spine and spinal cord, before we go further in this presentation there are some terms to know to aid understanding.
➢Neural tube; The neural tube forms the early brain and spine, As development progresses, the top of the neural tube becomes the brain, and the rest of the tube becomes the spinal cord. An NTD happens when this tube doesn't close completely somewhere along its length. Neural tube closure is completed 28 days (four weeks) from conception.
➢Alpha fetoprotein; AFP is a protein that the liver makes when its cells are growing and dividing to make new cells. AFP is normally high in unborn babies. After birth, AFP levels drop very low. Healthy children and adults who aren't pregnant have very little AFP in their blood. Maternal AFP serum level is used to screen for Down syndrome, neural tube defects, and other chromosomal abnormalities.
➢Spinal bifida; Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD).
Nursing management of myelomeningocele
Types of spinal Bifida
Pathophysiology of myelomeningocele
My name is Dahianara Moran and I believe being the parent of a child with Spina Bifida is like having a sixth sense, something like a Super Mom. We learn quickly how to defend our little ones from the awkward moments, but most important, we come to enjoy the little things, value our moments, and commit to change the way the world defines “Disability”.
Spina bifida is a birth defect that occurs when the spine and spinal cord don't form properly. It falls under the broader category of NTD (Neural Tube Defects).
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
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The four main behavioral effects of AUD are impaired control over
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effects (tolerance, withdrawal). This chapter presents an overview
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the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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3. Conditions in Children affecting Bowel Function
• Hirschsprungs
• Spinal cord injury
• Sacral agenesis
• Necrotising Enterocolitis NEC
• Ehlers–Danlos syndromes EDS
• Spina Bifida / hydrocephalus
4. Spinal Cord Injury
• Neurogenic bowel
• Level of injury will determine
function and bowel dysfunction
• Specialist care: paediatrics
and / or Specialist Spinal Centre
Cervical
Thoracic
Lumbar
Sacral
Coccygeal
C1-C3 Neck Muscles
C4 Diaphragm
C5 Deltoid (shoulder)
C6 Wrist
C7 Triceps
C7-C8 Fingers
T1 Hand
T2-T12 Intercostals (Trunk)
T7-L1 Abdominals
T11-L2 Ejaculation
L2 Hips
L3 Quadriceps
L4-L5 Hamstrings – Knee
L4-S1 Foot
S2 Penile erection
S2-S3 Bowel and bladder
5. Sacral agenesis
• Congenital disorder
• Abnormal development of
lower spine whilst developing
• 1:25,000 live births
• Absence of sacrum
6. Necrotising Enterocolitis (NEC)
• Neonatal condition
• 1: 250 live Births
• Premature, low birth weight babies
and in fewer babies born at term
• 1:4 babies will require surgery
• 3:5 babies will require further surgery
• 3 babies in UK die every
week with NEC
Diseased part
of bowel removed
Ostomy created Cut ends of
bowel joined
First surgery Second surgery
(weeks later)
7. Ehlers–Danlos syndromes (EDS)
• Genetic tissue disorder –
often misdiagnosed
• Symptoms include:
loose joints, stretchy skin
• 1:5000 globally
• No cure. Prognosis depends
on type of EDS
• Heartburn / Constipation /
Stress incontinence
10. Spina Bifida – Split spine
• Spina bifida is when a baby's spine and
spinal cord does not develop properly in
the womb, causing a gap in the spine.
• In spina bifida, part of the neural tube does not
develop or close properly, leading to defects in the
spinal cord and bones of the spine (vertebrae).
• Spina bifida is a type of neural tube defect.
The neural tube is the structure that eventually
develops into the baby's brain and spinal cord.
• The neural tube starts to form in early pregnancy
and closes about 4 weeks after conception.
Dura Mater
Spinal Cord
Spinal Fluid
Vertebra
11. Spina Bifida
Spina bifida occulta
(opened posterior vertebral body)
Meningocele
(protrusion of the meninges)
Myelomeningocele
(protrusion and opened spinal cord)
12. Types of Spina Bifida – Open SB
• Myelomeningocele is the most serious and more common of the two forms of
cystic spina bifida. Here the cyst not only contains tissue and cerebrospinal fluid
(CSF) but also nerves and part of the spinal cord. The exposed spinal cord is
damaged by the fluid in the womb during pregnancy and may also not develop
properly. As a result, there is nearly always some resulting paralysis and loss of
sensation. Nerves to and from the spinal cord emerging below the damaged
region may not pass messages to the brain. The extent of this can be patchy and
difficult to predict.
• The lower on the spine, and smaller the lesion, the less severe the resulting
impairments are likely to be. Bladder and bowel problems occur in most people
with myelomeningocele, as the nerves come from the very bottom of the spinal
cord, and are always below the lesion. It is also necessary to have intact nerve
pathways to the brain for complete control and sensation.
13.
14.
15. Types of Spina Bifida
Meningocele
In this form, the sac contains meninges (tissues
which cover the brain and spinal cord) and CSF,
but no spinal tissue. Development of the spinal
cord may be affected, but impairment is usually
less severe than myelomeningocele. Meningocele
is the least common form of spina bifida.
Spina Bifida Occulta
Spina bifida occulta (SBO) is a type of spinal
dysraphism or ‘closed’, skin-covered form
of spina bifida. Estimates vary, but between
5% and 10% of people may have spina bifida
occulta.
Closed Spina Bifida
Open Spina Bifida
16. Hydrocephalus
• A build up of cerebrospinal fluid on the
brain. Hydrocephalus can have a range
of physical and cognitive effects.
• Congenital hydrocephalus means
it is present at birth.
• Can be genetic, due to a maternal
infection or cysts in brain.
• Acquired hydrocephalus means
it has occurred during life.
• Maybe due to haemorrhage,
prematurity, tumour, meningitis.
17. Folic Acid
Folic acid before and during pregnancy
• Recommended dose 400 micrograms folic acid tablet every day
before pregnancy and until 12 weeks of pregnancy.
• Folic acid can help prevent birth defects known as neural tube
defects, including spina bifida.
• If folic acid is not taken before pregnancy, it should be started
as soon as pregnancy is confirmed.
• Eating foods that contain folate (the natural form of folic acid),
such as green leafy vegetables are recommended.
• Some breakfast cereals and some fat spreads, such as margarine,
may have folic acid added to them.
• It's difficult to get the amount of folate recommended for a healthy
pregnancy from food alone, which is why it's important to take a
folic acid supplement.
18. Vitamin B12
• Taking vitamin B12
• Vitamin B12 works closely with folate, and low levels in the
bloodstream increase the chance of the baby having NTD.
Many foods rich in B12 are ‘out of fashion’ these days, such as
eggs and red meat; vegetarians and vegans may need to take
extra B12 to get enough.
19. Challenges for the child
with bowel issues
• Negative impact on quality of life
• Are still taboo to talk about
• Lack of knowledge about treatment options
is often the reason why some children are
left untreated, or get suboptimal treatment
• Often other co-morbidities
• Potential bullying
20. Under 3’s treatment
• Laxatives
• Anti diarrhoeal medication
• Abdominal massage
• Surgery