The document discusses the concept of a "blue brain" or virtual brain being developed by IBM to function like the human brain. It explains that a virtual brain is an artificial brain that can think and respond like the natural brain. The key reasons for developing a virtual brain are to preserve human intelligence after death and have intelligent brains available to society. Current research involves simulating the brain's systems to create a 3D model and uploading a person's life experiences and brain structure into a computer through the use of nanobots. Challenges include developing very powerful hardware, software, and nanobots to interface the natural and virtual brains. Potential advantages are remembering things without effort and understanding animal thinking, while disadvantages are dependency on computers and
Today scientists are in research to create an artificial brain that can think, respond,
take decision, and keep anything in memory. The main aim is to upload human brain into
machine. So that man can think, take decision without any effort. After the death of the
body, the virtual brain will act as the man. So, even after the death of a person we will not
lose the knowledge, intelligence, personalities, feelings and memories of that man, that can
be used for the development of the human society. Technology is growing faster than
everything. IBM is now in research to create a virtual brain, called “Blue brain”.
Blue brain enables humans to give new dimensions to science and technology and make enormous development in making the best possible enlightenment to the present scenario.the details can be seen by going though the power point presentation
Today scientists are in research to create an artificial brain that can think, respond,
take decision, and keep anything in memory. The main aim is to upload human brain into
machine. So that man can think, take decision without any effort. After the death of the
body, the virtual brain will act as the man. So, even after the death of a person we will not
lose the knowledge, intelligence, personalities, feelings and memories of that man, that can
be used for the development of the human society. Technology is growing faster than
everything. IBM is now in research to create a virtual brain, called “Blue brain”.
Blue brain enables humans to give new dimensions to science and technology and make enormous development in making the best possible enlightenment to the present scenario.the details can be seen by going though the power point presentation
The Blue Brain Project is an attempt to create a synthetic brain by reverse-engineering the mammalian brain down to the molecular level. The aim of the project, founded in May 2005 by the Brain and Mind Institute of the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, is to study the brain's architectural and functional principles.
The Blue Brain, a Swiss national brain initiative, aims to create a digital reconstruction of the brain by reverse-engineering mammalian brain circuitry. The mission of the project, founded in May 2005 by the Brain and Mind Institute of the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, is to use biologically-detailed digital reconstructions and simulations of the mammalian brain (brain simulation) to identify the fundamental principles of brain structure and function in health and disease.
It is said that within 30 years we will be able to scan ourselves into computers.
With the advancement in technology, human, the ultimate source of information and discovery should
also be preserved. In other words, human is does not live for thousands of years but the information in his mind
could be saved and used for several thousands of years. The technology helpful in this activity is Blue Brain.
The Blue Brain Project is an attempt to create a synthetic brain by reverse-engineering the mammalian brain down to the molecular level. The aim of the project, founded in May 2005 by the Brain and Mind Institute of the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, is to study the brain's architectural and functional principles.
The Blue Brain, a Swiss national brain initiative, aims to create a digital reconstruction of the brain by reverse-engineering mammalian brain circuitry. The mission of the project, founded in May 2005 by the Brain and Mind Institute of the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, is to use biologically-detailed digital reconstructions and simulations of the mammalian brain (brain simulation) to identify the fundamental principles of brain structure and function in health and disease.
It is said that within 30 years we will be able to scan ourselves into computers.
With the advancement in technology, human, the ultimate source of information and discovery should
also be preserved. In other words, human is does not live for thousands of years but the information in his mind
could be saved and used for several thousands of years. The technology helpful in this activity is Blue Brain.
How can we harness the Human Brain Project to maximize its future health a...SharpBrains
In early 2013, the European Union selected the Human Brain Project, coordinated by Lausanne’s Federal Institute of Technology (EPFL), as the recipient of over 1 billion euros/ 1.3 billion dollars over the next ten years. How can the research agenda of this major initiative, and closely related ones, be organized and augmented with partnerships with the private sector and cross-sector stakeholders? How can we start building brain heath innovation platforms and delivery systems at the intersection of neuroscience, IT, and engineering?
- Chair: Hilal Lashuel, Associate Professor at the Swiss Federal Institute of Technology-Lausanne (EPFL), YGL Class of 2012
- Sean Hill, co-Director of the Blue Brain Project and co-Director of Neuroinformatics in the Human Brain Project (HBP) at the Swiss Federal Institute of Technology-Lausanne (EPFL)
This session took place at the 2013 SharpBrains Virtual Summit: http://sharpbrains.com/summit-2013/agenda/
Here blue brain technology is discussed .
The IBM is now developing a virtual brain known as the BLUE BRAIN , It would be the worlds first virtual brain.
Human brain is the most valuable creation of God. The man is intelligent because of the brain. "Blue brain" is the name of the world’s first virtual brain. That means a machine can function as human brain. Today scientists are in research to create an artificial brain that can think, response, take decision, and keep anything in memory. The main aim is to upload human brain into machine. So that man can think, take decision without any effort. After the death of the body, the virtual brain will act as the man .So, even after the death of a person we will not lose the knowledge, intelligence, personalities, feelings and memories of that man that can be used for the development of the human society.
Blue Brain Technology is an attempt to reverse engineer the human brain and create simulations inside a computer. This way, we can access someone's brain even when they are not around.
This is a complete report on the topic BLUE BRAIN TECHNOLOGY.It's a very big project and it is also very much costly and IBM is working on this project .EPFL(Ecole Polytechnique Federal de lausaane) working on this and swiss government providing the funding to this project and on movie maker is also making a movie on this technology.There is a youtube channel is also available.
The Blue Brain Project is an attempt to reverse engineer the human brain and recreate it at the cellular level inside a computer simulation. The project was founded in May 2005 by Henry Markram at the EPFL in Lausanne, Switzerland. Goals of the project are to gain a complete understanding of the brain and to enable better and faster development of brain disease treatments.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
2. Seminar
on
BLUE BRAIN
BY
P.R.Vamsi krishna
08Q61A0559
3. Contents:
1. Introduction
2. What is blue brain?
3. What is virtual brain?
4. Why we need virtual brain?
5. Function of brain
6.Uploading human brain
7.Current research work
8.Hardware & software requirements
9.Advantages & Disadvantages
10.Conclusion
5. What is blue brain?
“Blue brain” –The name of the world’s first
virtual brain. That means a machine that can
function as human brain.
Is it possible..? Answer is “yes”
The IBM is now developing a virtual brain
known as the Blue brain. It would be the
world’s first virtual brain.
6. What is virtual brain?
We can say Virtual brain is an artificial brain,
which does not actually the natural brain, but
can act as the brain.
It can think like brain, take decisions based on
the past experience, and response as the
natural brain can.
7. Why we need virtual brain ?
Today we are developed because of our
intelligence. Intelligence is the inborn quality
that can not be created .Some people have
this quality ,so that they can think up to such
an extent where other can not reach .
Human society is always need of such
intelligence and such an intelligent brain to
have with. But the intelligence is lost along
with the body after the death. The virtual
brain is a solution to it.
8. Function of natural brain?
The human ability to feel, interpret and even
see is controlled, in computer like
calculations, by the magical nervous system.
One of the worlds most "intricately
organized" electron mechanisms is the
nervous system. Not even engineers have
come close to making circuit boards and
computers as delicate and precise as the
nervous system.
9. Sensory input:
When our eyes see something or our hands touch a warm
surface, the sensory cells, also known as Neurons, send a
message straight to your brain.
Integration:
Integration is best known as the interpretation of things we have
felt, tasted, and touched with our sensory cells, also known as
neurons, into responses that the body recognizes.
Nose
Once the smell of food has reached your nose, which is lined with
hairs, it travels to an olfactory bulb, a set of sensory nerves.
Eye
Seeing is one of the most pleasing senses of the nervous system.
Tongue
A set of microscopic buds on the tongue divide everything we eat
and drink into four kinds of taste: bitter, sour, salty, and sweet.
10. Uploading human brain:
The uploading is possible by the use of small
robots known as the Nanobots
These robots are small enough to travel
through out our circulatory system. They will
be able to monitor the activity and structure
of our central nervous system.
They will be able to provide an interface with
computers that is as close as our mind can be
while we still reside in our biological form.
11. Nanobots could also carefully scan the
structure of our brain, providing a complete
readout of the connections.
This information, when entered into a
computer, could then continue to function as
us.
Thus the data stored in the entire brain will
be uploaded into the computer.
12. CURRENT RESEARCH WORK
1.
IBM, in partnership with scientists at
Switzerland's Ecole Polytechnique Federale
de Lausanne's (EPFL) Brain and Mind
Institute will begin simulating the brain's
biological systems and output the data as a
working 3-dimensional model that will
recreate the high-speed electro-chemical
interactions that take place within the brain's
interior.
13. CURRENT RESEARCH WORK
2.
Researchers at Microsoft's Media Presence Lab
are developing a "virtual brain," a PC-based
database that holds a record of an individual's
complete life experience. Called MyLifeBits
3.
According to the new scientist Magazine report
Rodrigo Laje and Gabriel Mindlin of the
University of Buenos Aires in Argentina have
devised a computer model of a region of the
brain called the RA nucleus which controls
muscles in the lungs and vocal folds.
14. Hardware & software
requirements
1. A super computer.
2. Memory with a very large storing capacity.
3. Processor with a very high processing power.
4. A very wide network.
5. A program to convert the electric impulses
from the brain to input signal, which is to be
received by the computer, and vice versa.
6. Very powerful Nanobots to act as the
interface between the natural brain and the
computer
15. Advantages
1. We can remember things without any effort.
2. Decision can be made without the presence of a person.
3. Even after the death of a man his intelligence can be used.
4. The activity of different animals can be understood. That means
by interpretation of the electric impulses from the brain of the
animals, their thinking can be understood easily.
5. It would allow the deaf to hear via direct nerve stimulation, and
also be helpful for many psychological diseases. By down loading
the contents of the brain that was uploaded into the computer,
the man can get rid from the mad ness.
16. Disadvantages
Further, there are many new dangers these
technologies will open. We will be susceptible to
new forms of harm.
1. We become dependent upon the computer
systems.
2. Others may use technical knowledge against us.
3. Computer viruses will pose an increasingly
critical threat.
4. The real threat, however, is the fear that people
will have of new technologies. That fear may
culminate in a large resistance. Clear evidence of
this type of fear is found today with respect to
human cloning.
17. Conclusion
In conclusion, we will be able to transfer
ourselves into computers at some point. Most
arguments against this outcome are
seemingly easy to circumvent. They are either
simple minded, or simply require further time
for technology to increase. The only serious
threats raised are also overcome as we note
the combination of biological and digital
technologies.