This lecture aims to teach students about water distribution and buffers in the body. It will provide an overview of water and electrolytes, explain how water acts as an ideal solvent, define pH and discuss hydrogen ion production. It will emphasize the importance of maintaining body fluid pH, define buffers, explain how they work, identify bicarbonate as the major buffer and discuss clinical states when pH is disturbed.

1. Lecture Objectives (Foundation Module)
Dissociation of water & concept of Buffers
At the end of lecture student should be able to:
1. To have an overview of normal distribution of water and electrolytes in
body fluids.
2. To appreciate the importance of water as an Ideal biologic solvent.
3. Define pH.
4. Discuss the hydrogen ion production in body.
5. To appreciate the importance of maintaining the pH of body fluids.
6. Define buffers.
7. Explain the mechanism of action buffers.
8. Justify that bicarbonate buffer is the major buffer of body.
9. Enumerate the clinical states of disturbed pH.