The document discusses various applications of 3D printing in the medical field, including hearing aids, surgical guides and tools, prosthetics, surgical learning tools, implants, modeling patient anatomy, and bandages. It outlines how 3D printing allows for customization, presurgical planning, education and training, testing of medical devices, and more personalized treatment options in a safe, cost-effective manner.
Industrial adoption of 3D Printing has been increasing gradually from prototyping to manufacturing of low volume customized parts. The need for customized implants like tooth crowns, hearing aids, and orthopedic-replacement parts has made the life sciences industry an early adopter of 3D Printing. Demand for low volume spare parts of vintage cars and older models makes 3D printing very useful in the automotive industry. It is possible to 3D print in a wide range of materials that include thermoplastics, thermoplastic composites, pure metals, metal alloys and ceramics. Right now, 3D printing as an end-use manufacturing technology is still in its infancy. But in the coming decades, and in combination with synthetic biology and nanotechnology, it has the potential to radically transform many design, production and logistics processes.
3D Printing Technology PPT by ajaysingh_02AjaySingh1901
This PPT make on 3D printing Technology or additive manufacturing in which we cover the need, history importants, future scope, trend before the 3DP, advantage and disadvantage, limitations, application of 3DP
Industrial adoption of 3D Printing has been increasing gradually from prototyping to manufacturing of low volume customized parts. The need for customized implants like tooth crowns, hearing aids, and orthopedic-replacement parts has made the life sciences industry an early adopter of 3D Printing. Demand for low volume spare parts of vintage cars and older models makes 3D printing very useful in the automotive industry. It is possible to 3D print in a wide range of materials that include thermoplastics, thermoplastic composites, pure metals, metal alloys and ceramics. Right now, 3D printing as an end-use manufacturing technology is still in its infancy. But in the coming decades, and in combination with synthetic biology and nanotechnology, it has the potential to radically transform many design, production and logistics processes.
3D Printing Technology PPT by ajaysingh_02AjaySingh1901
This PPT make on 3D printing Technology or additive manufacturing in which we cover the need, history importants, future scope, trend before the 3DP, advantage and disadvantage, limitations, application of 3DP
3D Printing Technology seminar report by ajaysingh_02AjaySingh1901
This is the Report file about 3D Printing Technolog and additive manufacturing in which we cover all the basics of 3DP
History,need, development,scope, availablity,future scope,trend before the 3DP, Advantage and disadvantages, limitations, Application and Appliances.
3D printing is called as additive manufacturing technology where a three dimensional object is created by laying down successive layers of material. It is also known as rapid prototyping, is a mechanized method whereby 3D objects are quickly made on a reasonably sized machine connected to a computer containing blueprints for the object. It is working under the principle of Fused Deposition Modelling (FDM). The 3D printing concept of custom manufacturing is exciting to nearly everyone. The basic principles include materials cartridges, flexibility of output, and translation of code into a visible pattern.3D Printers are the machines that produce physical 3D models from digital data by printing layer by layer. It can make physical models of objects either designed with a CAD program or scanned with a 3D Scanner. Here we are going to propose a model report on design and fabrication of a 3D printer.
Modelling and 3D Printing of Differential Gear Boxijtsrd
The main aim of the project is to focus on the modeling and 3D printing of differential gear box. Differential permit each of the driving wheels to rotate at different speeds, while for most vehicles supplying equal torque to each of them. A vehicles wheels rotate at divergent speeds, mainly when turning corners. The differential is designed to operate a pair of wheels with same torque while permit them to rotate at different speeds. Differential gear box is designed in CATIA V5 software and manufactured using additive manufacturing 3D printing . The function of gear is to protect and provide a platform for gear transmission. It also provides supports for moving parts and protection from outside environmental condition. Yogesh Avula | Vanga Rajeev Narayana Reddy | VojaAnand Swaroop | Varikuppala Srisailam ""Modelling and 3D Printing of Differential Gear Box"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23287.pdf
Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/23287/modelling-and-3d-printing-of-differential-gear-box/yogesh-avula
6 Key Takeaways for the State of 3D Printing - 2016Sculpteo
Our 2016 edition of The State of 3D Printing is out. Almost 1000 participants responded and shared their experience and expectations about 3D printing bringing incomparable depth to this survey. You'll find the latest trends in the 3D printing industry and know how to gear up your 3D printing strategy for success.
3D Printing - shaping the future of formulation developmentMerck Life Sciences
Watch the presentation of this webinar here: https://bit.ly/3pLd4cq
In our webinar we will take you on a journey to discover the latest trends in additive manufacturing for developing pharmaceutical dosage forms. We provide you a fundamental understanding of the different technologies currently evaluated in pharmaceutical industry. A clear definition of the key aspects of the individual technologies ensure a strong basis for future implementation of this technology in pharmaceutical manufacturing.
We will review the existing technologies and outline the potential for the targeted application.
An important aspect will be the filament-based 3D printing technology.
A case study will be presented on how a hot melt extrusion process can be optimized for filament production. Material properties as well as down-stream equipment drive a successful implementation.
We will also present a novel melt-based 3D printing approach, which can directly create the final dosage form out of powder. A drop-based deposition of the polymer melt ensures a new level of accuracy and individualization when it comes to the finishing of the final form.
In this webinar, you will learn:
• Additive manufacturing: Basics and potential application fields
• Overview of existing 3D printing approaches and their relevance in Pharmaceutical Industry
• Background and advantages of extrusion-based 3D printing
• Requirements for FDM (fused deposition modeling) based technologies
• New advanced technical approaches for direct shaping of 3D printed tablets
3D printing market - a global study (2014-2022)BIS Research
The report presents a detailed market analysis of 3D printing and Additive Manufacturing by incorporating complete pricing and cost analysis of 3D printers and materials. Besides porter’s and PESTLE analysis of the market have also been done. The report deals with all the driving factors, restraints, and opportunities with respect to the 3D printing and Additive Manufacturing market, which are helpful in identifying trends and key success factors for the industry.
Lastly, the current market landscape is covered with detailed competitive landscape and company profiles of all key players across the ecosystem. The report also formulates the entire value chain of the market, along with industry trends of 3D printing application industries and materials used with emphasis on market timelines & technology road-maps
in this presentation i have discussed about 4D Printing technology. you can watch out it in video form on my You Tube channel https://youtu.be/ZDaurFz2byc
Power from the burnt gases in the combustion chamber is delivered to the crankshaft through the piston, piston pin and connecting rod. The crankshaft changes reciprocating motion of the piston in cylinder to the rotary motion of the flywheel. Crankshaft is designed for multi cylinder engine and its 3D model is created using modeling software CATIA V5R20.The 3D printer prints the CATIA design layer by layer forming a real object. 3D printing process is derived from inkjet desktop printers in which multiple deposit jets and the printing material, layer by layer derived from the CATIA data. 3D printing significantly challenges mass production processes in the future. This type of printing is predicted to influence industries, like automotive, medical, education, equipment, consumer products industries and various businesses. T. Venkata Ramana | Sagam Kunta Subhash | Sangem Devendra Kumar | Vanga Balakrishna ""Modelling and 3D Printing of Crankshaft"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23224.pdf
Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/23224/modelling-and-3d-printing-of-crankshaft/t-venkata-ramana
Integrating parametric design with robotic additive manufacturing for 3D clay...Antonio Arcadu
ABSTRACT This paper presents an ongoing work in relation to the development of a parametric design algorithm and an automated system for additive manufacturing that aims to be implemented in 3D clay printing tasks. The purpose of this experimental study is to establish a first insight and provide information as well as guidelines for a comprehensive and robust additive manufacturing methodology that can be implemented in the area of 3D clay printing, aiming to be widely available and open for use in the relevant construction industry. Specifically, this paper emphasizes on the installation of an industrial extruder for 3D clay printing mounted on a robot, on toolpath planning process using a parametric design environment and on robotic execution of selected case studies. Based on existing 3D printing technology principles and on available rapid prototyping mechanisms, this process suggests an algorithm for system’s control as well as for robotic toolpath development applied in additive manufacturing of small to medium objects. The algorithm is developed in a parametric associative environment allowing its flexible use and execution in a number of case studies, aiming to tentatively test the effectiveness of the suggested robotic additive manufacturing workflow and their future implementation in large scale examples.
Autors: O. Kontovourkisa and G. Tryfonos
3D Printing (Additive Manufacturing) PPT & PDFmangadynasty5
Definition:
3D Printing, also known as Additive Manufacturing (AM), is a revolutionary manufacturing process that constructs three-dimensional objects layer by layer from a digital model. Unlike traditional subtractive manufacturing methods that involve cutting or shaping material to create an object, 3D printing adds material gradually, allowing for highly complex and customized designs.
3D Printing Technology seminar report by ajaysingh_02AjaySingh1901
This is the Report file about 3D Printing Technolog and additive manufacturing in which we cover all the basics of 3DP
History,need, development,scope, availablity,future scope,trend before the 3DP, Advantage and disadvantages, limitations, Application and Appliances.
3D printing is called as additive manufacturing technology where a three dimensional object is created by laying down successive layers of material. It is also known as rapid prototyping, is a mechanized method whereby 3D objects are quickly made on a reasonably sized machine connected to a computer containing blueprints for the object. It is working under the principle of Fused Deposition Modelling (FDM). The 3D printing concept of custom manufacturing is exciting to nearly everyone. The basic principles include materials cartridges, flexibility of output, and translation of code into a visible pattern.3D Printers are the machines that produce physical 3D models from digital data by printing layer by layer. It can make physical models of objects either designed with a CAD program or scanned with a 3D Scanner. Here we are going to propose a model report on design and fabrication of a 3D printer.
Modelling and 3D Printing of Differential Gear Boxijtsrd
The main aim of the project is to focus on the modeling and 3D printing of differential gear box. Differential permit each of the driving wheels to rotate at different speeds, while for most vehicles supplying equal torque to each of them. A vehicles wheels rotate at divergent speeds, mainly when turning corners. The differential is designed to operate a pair of wheels with same torque while permit them to rotate at different speeds. Differential gear box is designed in CATIA V5 software and manufactured using additive manufacturing 3D printing . The function of gear is to protect and provide a platform for gear transmission. It also provides supports for moving parts and protection from outside environmental condition. Yogesh Avula | Vanga Rajeev Narayana Reddy | VojaAnand Swaroop | Varikuppala Srisailam ""Modelling and 3D Printing of Differential Gear Box"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23287.pdf
Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/23287/modelling-and-3d-printing-of-differential-gear-box/yogesh-avula
6 Key Takeaways for the State of 3D Printing - 2016Sculpteo
Our 2016 edition of The State of 3D Printing is out. Almost 1000 participants responded and shared their experience and expectations about 3D printing bringing incomparable depth to this survey. You'll find the latest trends in the 3D printing industry and know how to gear up your 3D printing strategy for success.
3D Printing - shaping the future of formulation developmentMerck Life Sciences
Watch the presentation of this webinar here: https://bit.ly/3pLd4cq
In our webinar we will take you on a journey to discover the latest trends in additive manufacturing for developing pharmaceutical dosage forms. We provide you a fundamental understanding of the different technologies currently evaluated in pharmaceutical industry. A clear definition of the key aspects of the individual technologies ensure a strong basis for future implementation of this technology in pharmaceutical manufacturing.
We will review the existing technologies and outline the potential for the targeted application.
An important aspect will be the filament-based 3D printing technology.
A case study will be presented on how a hot melt extrusion process can be optimized for filament production. Material properties as well as down-stream equipment drive a successful implementation.
We will also present a novel melt-based 3D printing approach, which can directly create the final dosage form out of powder. A drop-based deposition of the polymer melt ensures a new level of accuracy and individualization when it comes to the finishing of the final form.
In this webinar, you will learn:
• Additive manufacturing: Basics and potential application fields
• Overview of existing 3D printing approaches and their relevance in Pharmaceutical Industry
• Background and advantages of extrusion-based 3D printing
• Requirements for FDM (fused deposition modeling) based technologies
• New advanced technical approaches for direct shaping of 3D printed tablets
3D printing market - a global study (2014-2022)BIS Research
The report presents a detailed market analysis of 3D printing and Additive Manufacturing by incorporating complete pricing and cost analysis of 3D printers and materials. Besides porter’s and PESTLE analysis of the market have also been done. The report deals with all the driving factors, restraints, and opportunities with respect to the 3D printing and Additive Manufacturing market, which are helpful in identifying trends and key success factors for the industry.
Lastly, the current market landscape is covered with detailed competitive landscape and company profiles of all key players across the ecosystem. The report also formulates the entire value chain of the market, along with industry trends of 3D printing application industries and materials used with emphasis on market timelines & technology road-maps
in this presentation i have discussed about 4D Printing technology. you can watch out it in video form on my You Tube channel https://youtu.be/ZDaurFz2byc
Power from the burnt gases in the combustion chamber is delivered to the crankshaft through the piston, piston pin and connecting rod. The crankshaft changes reciprocating motion of the piston in cylinder to the rotary motion of the flywheel. Crankshaft is designed for multi cylinder engine and its 3D model is created using modeling software CATIA V5R20.The 3D printer prints the CATIA design layer by layer forming a real object. 3D printing process is derived from inkjet desktop printers in which multiple deposit jets and the printing material, layer by layer derived from the CATIA data. 3D printing significantly challenges mass production processes in the future. This type of printing is predicted to influence industries, like automotive, medical, education, equipment, consumer products industries and various businesses. T. Venkata Ramana | Sagam Kunta Subhash | Sangem Devendra Kumar | Vanga Balakrishna ""Modelling and 3D Printing of Crankshaft"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23224.pdf
Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/23224/modelling-and-3d-printing-of-crankshaft/t-venkata-ramana
Integrating parametric design with robotic additive manufacturing for 3D clay...Antonio Arcadu
ABSTRACT This paper presents an ongoing work in relation to the development of a parametric design algorithm and an automated system for additive manufacturing that aims to be implemented in 3D clay printing tasks. The purpose of this experimental study is to establish a first insight and provide information as well as guidelines for a comprehensive and robust additive manufacturing methodology that can be implemented in the area of 3D clay printing, aiming to be widely available and open for use in the relevant construction industry. Specifically, this paper emphasizes on the installation of an industrial extruder for 3D clay printing mounted on a robot, on toolpath planning process using a parametric design environment and on robotic execution of selected case studies. Based on existing 3D printing technology principles and on available rapid prototyping mechanisms, this process suggests an algorithm for system’s control as well as for robotic toolpath development applied in additive manufacturing of small to medium objects. The algorithm is developed in a parametric associative environment allowing its flexible use and execution in a number of case studies, aiming to tentatively test the effectiveness of the suggested robotic additive manufacturing workflow and their future implementation in large scale examples.
Autors: O. Kontovourkisa and G. Tryfonos
3D Printing (Additive Manufacturing) PPT & PDFmangadynasty5
Definition:
3D Printing, also known as Additive Manufacturing (AM), is a revolutionary manufacturing process that constructs three-dimensional objects layer by layer from a digital model. Unlike traditional subtractive manufacturing methods that involve cutting or shaping material to create an object, 3D printing adds material gradually, allowing for highly complex and customized designs.
The use of 3D printing is gradually increasing and the technologies developed in the 3D printing also increases. This presentation is about the various technologies present the market.
In the recent decades of development of manufacturing and production engineering, 3D printing technology has emerged as one of the most promising area for research and development. With the availability of flexible and user friendly manufacturing and interfacing system, the 3D printing technology has attracted a lot of researchers form keen aspects of their field.
Medical Engineering is the branch of science that deal with the application of technological aspects in solving medical problems. With the merger in these two vast fields a lot of problems has been answered and the development of new things is on their verge of initiation.
In the recent decade both the engineers and medical researchers have worked on integration of technologies to solve the medical problems globally. In the scenario, a lot of technology like 3D printed Heart, Kidneys, etc., & physical implants like teeth’s, bones and medical support.
In this report, I have tried to acknowledge the work done in the field with their importance in the ever changing scenario of the world.
Course Objectives:
Students undergoing this course would
Understand different methods of 3D Printing.
Gain knowledge about simulation of FDM process
Estimate time and material required for manufacturing a 3D component
Course Outcomes:
Upon the successful completion of course, students will be able to
Explain different types of 3d Printing techniques
Identify parameters for powder binding and jetting process
Determine effective use of ABS material for 3D Printing
Apply principles of mathematics to evaluate the volume of material require.
Module 1:
Introduction to Prototyping, Working of 3D Printer, Types of 3D printing Machines:
Exp 1: Modelling of Engineering component and conversion of STL format.
Exp 2: Slicing of STL file and study of effect of process parameter like layer thickness,
Orientation and infill on build time using software.
Exercise 1 : Component-1
Exercise 2 : Component-2
Module 2:
Exp 1 : 3D Printing of modeled component by varying layer thickness.
Exp 2 : 3D Printing of modeled component by varying orientation.
Exp 3: 3D Printing of modeled component by varying infill.
Module 3:
Study on effect of different materials like ABS, PLA, Resin etc, and dimensional accuracy.
Module 4:
Identifying the defects in 3D Printed components.
Module 5
Exp1: Modelling of component using 3D Scanner of real life object of unknown dimension
in reverse engineering.
Exp 2: 3D Printing of above modeled component.
Additive manufacturing (AM) or additive layer manufacturing (ALM) is the industrial production name for 3D printing, a computer controlled process that creates three dimensional objects by depositing materials, usually in layers.
AM is a rapidly growing field that is having an impact on multiple industries by simplifying the process to go from a 3D model to a finished product.
In contrast to conventional manufacturing processes, AM fabricates objects by adding materials as required which eliminates the necessity of subtracting materials (by means of machining, milling, carving, etc.) to obtain desired shapes.
AM can advantageously fabricate complex geometries with no part-specific tooling and much less waste material.
In the construction sector, architectural models have been created with AM methods for more than a decade.
Recent years have seen a vast increase in research on printing methods for building components.
AM allows building companies to produce geometrically complex structures, to vary materials within a component according to its functions, and to automate the construction process starting from a digital model.
The technology can bring significant benefits to the construction industry in terms of increased customization, reduced construction time, reduced manpower, and construction cost.
Additive manufacturing (AM) is the industrial production name for 3D printing, a computer controlled process that creates three dimensional objects by depositing materials, usually in layers,is a transformative approach to industrial production that enables the creation of lighter, stronger parts and systems. ... As its name implies, additive manufacturing adds material to create an object.
A tale of scale & speed: How the US Navy is enabling software delivery from l...sonjaschweigert1
Rapid and secure feature delivery is a goal across every application team and every branch of the DoD. The Navy’s DevSecOps platform, Party Barge, has achieved:
- Reduction in onboarding time from 5 weeks to 1 day
- Improved developer experience and productivity through actionable findings and reduction of false positives
- Maintenance of superior security standards and inherent policy enforcement with Authorization to Operate (ATO)
Development teams can ship efficiently and ensure applications are cyber ready for Navy Authorizing Officials (AOs). In this webinar, Sigma Defense and Anchore will give attendees a look behind the scenes and demo secure pipeline automation and security artifacts that speed up application ATO and time to production.
We will cover:
- How to remove silos in DevSecOps
- How to build efficient development pipeline roles and component templates
- How to deliver security artifacts that matter for ATO’s (SBOMs, vulnerability reports, and policy evidence)
- How to streamline operations with automated policy checks on container images
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
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See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
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👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
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Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
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2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
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Orchestrator execution result
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Leading Change strategies and insights for effective change management pdf 1.pdf
1609540014 lokesh
1. I
Mahatma Gandhi Mission’s
College of Engineering and Technology
Noida, U.P., India
Seminar Report
On
“APPLICATIONS OF 3D PRINTING IN MEDICAL”
As
Part of B. Tech Curriculum
Submitted by:
Lokesh chaudhary
VIII Semester
1609540014
Under the Guidance of:
Mr. Umesh Yadav
(Assistant Professor)
MGM’s COET, Noida
(Seminar Coordinator)
Mr. Ravindra ram
Submitted to:
HOD
Mechanical Engineering Department
MGM’s COET, Noida
2. ii
Mahatma Gandhi Mission’s
College of Engineering and Technology
Noida, U.P., India
Department of Mechanical Engineering
CERTIFICATE
This is to certify that Mr. LOKESH CHAUDHARY B. Tech. Mechanical Engineering, Class
TT-ME and Roll No. 1609540014has delivered seminar on the topic “APPLICATIONS
OF 3D PRINTING IN MEDICAL”. His seminar presentation and report during
the academic year 2019-2020 as the part of B. Tech Mechanical Engineering curriculum was
good.
(Guide) (Seminar coordinator) (Head of the Department)
3. iii
ACKNOWLEDGEMENT
I would like to express my deep sense of gratitude to my supervisor Mr. Umesh Yadav
(Assistant Professor, Department of Mechanical Engineering, M.G.M College of
Engineering and Technology, Noida, India) for his guidance, support and encouragement
throughout this seminar. Moreover, I would like to acknowledge the Department of Mechanical
Engineering, M.G.M College of Engineering and Technology, Noida, for providing me all
possible help during this seminar work. Moreover, I would like to sincerely thank everyone who
directly and indirectly helped me in completing this work.
(Lokesh chaudhary)
4. iv
ABSTRACT
3D printing is a new technology in constant evolution. It has rapidly expanded and is now being
used in health education. Patient-specific models with anatomical fidelity created from imaging
dataset have the potential to significantly improve the knowledge and skills of a new generation
of surgeons. This review outlines five technical steps required to complete a printed model:
They include selecting the anatomical area of interest, the creation of the 3D geometry, the
optimization of the file for the printing and the appropriate selection of the 3D printer and
materials. All of these steps require time, expertise and money. A thorough understanding of
educational needs is therefore essential in order to optimize educational value. At present, most
of the available printing materials are rigid and therefore not optimum for flexibility and
elasticity unlike biological tissue. We believe that the manipulation and tuning of material
properties through the creation of composites and/or blending materials will eventually allow for
the creation of patient-specific models which have both anatomical and tissue fidelity.
5. v
TABLE OF CONTENT
Certificate ii
Acknowledgement iii
Abstract iv
Table of Content v
List of Figure vi
CHAPTER 1: INTRODUCTION 1
1.1 Introduction 1
1.2 History 2
CHAPTER 2: TYPES OF 3D PRINTING 4
2.1 Stereolithography (Sla) Technology 4
2.2 Selective Laser Sintering (SLS) Technology 5
2.3 Laminated Object Manufacturing (Lom) Technology 6
CHAPTER 3: APPLICATIONS OF 3D PRINTERS IN MEDICAL 7
3.1 Hearing Aids 8
3.2 Surgical Guides and Tools 9
3.3 Prosthetics 10
3.4 Surgical Learning Tools 11
3.5 Implants 12
3.6 Anatomy of Patient 14
3.7 Bandages 15
CONCLUSION 17
REFERENCE 18
6. vi
LIST OF FIGURES
FIG.NO. DETAILS OF FIGURES PAGE NO.
1.1 3d Structure 1
2.1 Stereolithography (SLA) Technology 4
2.2 Selective Laser Sintering (SLS) Technology 5
2.3 Laminated Object Manufacturing (LOM) Technology 6
3.1 Hearing Aids 8
3.2 Surgical Guides and Tools 9
3.3 Surgery Tools 10
3.4 Prosthetics 11
3.5 Surgical Learning Tools 12
3.6 Implants 13
3.7 Anatomy of Patient 14
3.8 Bandages 15
7. 1
CHAPTER 1
INTRODUCTUON
1.1 Introduction
The rapid development of 3D printing has created new learning and teaching tool for medical
education. The ability to produce patient-specific in silicon models from digital imaging and
communication in medicine (DICOM) data derived during CT, MRI,or ultrasound scanning
has been coupled with new, less expensive 3D printing technology. Depending on the area of
interest, these printed models demonstrate anatomical and structural fidelity consistent with
the patient’s actual disease process. This fidelity has allowed learners to view and understand
gross pathology and structural relationships prior to surgical intervention. An improved
understanding and visualization have in turn allowed surgical teams to plan interventions
more accurately and guide margins of resection, model appropriate implant dimensions and
sometimes create the implant itself using 3D printing technology as shown in fig.1.1
Fig. 1.1 3D Structure
However, the vast majority of printed models are made with hard materials and only a few
presents some flexibility and elasticity. Although hard materials are sufficient to recreate
anatomical fidelity, it has been challenging to recreate models with tissue characteristics
8. 2
1.2 History
1974: David E. H. Jones laid out the concept of 3D printing in his regular column Ariadne in
the journal New Scientist
1981: Early additive manufacturing equipment and materials were developed in the 1980s. In
1981: Hideo Kodama of Nagoya Municipal Industrial Research Institute invented two additive
methods for fabricating three-dimensional plastic models with photo-hardening thermoset
polymer, where the UV exposure area is controlled by a mask pattern or a scanning fiber
transmitter
1984: On July 2nd 1984, American Entrepreneur Bill Masters filed a patent for his Computer
Automated Manufacturing Process and System (US 4665492).This filing is on record at
the USPTO as the first 3D printing patent in history; it was the first of three patents belonging
to Masters that laid the foundation for the 3D printing systems used today On 16 July
1984, Alain Le Mahout, Olivier de Witte, and Jean Claude André filed their patent for
the stereolithography process. The application of the French inventors was abandoned by the
French General Electric Company (now Alcatel-Alston) and CILAS (The Laser
Consortium). The claimed reason was "for lack of business perspective “Three weeks later in
1984, Chuck Hull of 3D Systems Corporation filed his own patent for a stereolithography fabrication
system, in curing photopolymers with ultraviolet light lasers. Hull defined the process as a "system for
generating three-dimensional objects by creating a cross-sectional pattern of the object to be
formed,” Hull's contribution was the STL (Stereolithography) file format and the digital slicing and
infill strategies common to many processes today.
1986: Charles Hull was granted a patent for his system, and his company, 3D Systems
Corporation released the first commercial 3D printer, the SLA-1.
1988: The technology used by most 3D printers to date—especially hobbyist and consumer-
oriented models—is fused deposition modeling, a special application of plastic extrusion,
developed in 1988 by S. Scott Crump and commercialized by his company Stratasys, which
marketed its first FDM machine in 1992.
AM processes for metal sintering or melting (such as selective laser sintering, direct metal
laser sintering, and selective laser melting) usually went by their own individual names in
the 1980s and 1990s. At the time, all metalworking was done by processes that are now called
non-additive (casting, fabrication, stamping, and machining); although plenty
of automation was applied to those technologies (such as by robot welding and CNC), the idea
of a tool or head moving through a 3D work envelope transforming a mass of raw
9. 3
material into a desired shape with a tool path was associated in metalworking only with
processes that removed metal (rather than adding it), such as CNC milling, CNC EDM, and
many others. But the automated techniques that added metal, which would later be called
additive manufacturing, were beginning to challenge that assumption. By the mid-1990s, new
techniques for material deposition were developed at Stanford and Carnegie Mellon
University, including micro casting]
and sprayed materials. Sacrificial and support materials
had also become more common, enabling new object geometries.
1993: The term 3D printing originally referred to a powder bed process employing standard
and custom inkjet print heads, developed at MIT by Emanuel Sachs in 1993 and
commercialized by Solingen Technologies, Extrude Hone Corporation, and Z Corporation.[
The year 1993 also saw the start of a company called Solids cape, introducing a high-
precision polymer jet fabrication system with soluble support structures, (categorized as a
"dot-on-dot" technique).
1995: In 1995 the Fraunhofer Society developed the selective laser melting process.
2009: Fused Deposition Modeling (FDM) printing process patents expired in 2009.
As the various additive processes matured, it became clear that soon metal removal would no
longer be the only metalworking process done through a tool or head moving through a 3D
work envelope transforming a mass of raw material into a desired shape layer by layer.
The 2010s were the first decade in which metal end use parts such as engine brackets and
large nuts would be grown (either before or instead of machining) in job production rather
than obligately being machined from bar stock or plate. It is still the case that casting,
fabrication, stamping, and machining are more prevalent than additive manufacturing in
metalworking, but AM is now beginning to make significant inroads, and with the advantages
of design for additive manufacturing, it is clear to engineers that much more is to come. As
technology matured, several authors had begun to speculate that 3D printing could aid
in sustainable development in the developing world.
2012: Folio develops a system for closing the loop with plastic and allows for any FDM or
FFF 3D printer to be able to print with a wider range of plastics.
10. 4
CHAPTER 2
DIFFERENT TYPES OF 3D PRINTERS
There are several types of 3d printers which are given below:
2.1 Stereo lithography (Sla) Technology
SLA is a fast prototyping process. Those who use this technology are serious about accuracy
and precision. It can produce objects from 3D CAD data (computer-generated) files in just a
few hours. This is a 3D printing process that’s popular for its fine details and exactness.
Machines that use this technology produce unique models, patterns, prototypes, and various
production parts. They do this by converting liquid photopolymers (a special type of plastic)
into solid 3D objects, one layer at a time. The plastic is first heated to turn it into a semi-liquid
form, and then it hardens on contact. The printer constructs each of these layers using an ultra
violet laser, directed by X and Y scanning mirrors. Just before each print cycle, a recoated
blade moves across the surface to ensure each thin layer of resin spreads evenly across the
object. The print cycle continues in this way, building 3D objects from the bottom up as
shown fig.2.1
Fig. 2.1 SLA Technology
11. 5
Once completed, someone takes the 3D object from the printer and detaches it carefully from
the platform. The 3D part will usually have a chemical bath to remove any excess resin. It’s
also common practice to post-cure the object in an ultra violet oven. What this does is render
the finished item stronger and more stable. Depending on the part, it may then go through a
hand sanding process and have some professional painting done. SLA printing has become a
favored economical choice for a wide variety of industries. Some of these include automotive,
medical, aerospace, entertainment, and also to create various consumer products.
2.2Selective Laser Sintering (SLS) Technology
The build platform, or bed, lowers incrementally with each successive laser scan. It’s a
process that repeats one layer at a time until it reaches the object’s height. There is un-sintered
support from other powders during the build process that surround and protect the model. This
means the 3D objects don’t need other support structures during the build. Someone will
remove the un-sintered powders manually after printing.
Fig. 2.2 SLS Technology
SLS produces durable, high precision parts, and it can use a wide range of materials. It’s a
perfect technology for fully-functional, end-use parts and prototypes. SLS is quite similar to
SLA technology with regards to speed and quality. The main difference is with the materials,
12. 6
as SLS uses powdered substances, whereas SLA uses liquid resins. It’s this wide variety of
available materials that makes SLA technology so popular for printing customized objects.
This technology as shown in fig2.2
2.3 Laminated Object Manufacturing (Lom) Technology
A Californian company called Helices Inc. (now Cubic Technologies), first developed LOM
as an effective and affordable method of 3D printing. A US design engineer called Fergana
pioneer in 3D printed technologies originally patented LOM.
Fig. 2.3 LOM Technology
LOM is a rapid prototyping system that works by fusing or laminating layers of plastic or
paper using both heat and pressure. A computer-controlled blade or laser cuts the object to the
desired shape. Once each printed layer is complete, the platform moves down by about 1/16th
of an inch, ready for the next layer. The printer then pulls a new sheet of material across the
substrate where it’s adhered by a heated roller. This basic process continues over and over
until the 3D part is complete. This technology is shown in fig.2.3
13. 7
CHAPTER 3
APPLICATIONS OF 3D PRINTERS IN MEDICAL
Every year, 3D printing offers more and more applications in the healthcare field helping to
save and improve lives in ways never imagined up to now. In fact, the 3D printing has been
used in a wide range of healthcare settings including, but not limited to cardiothoracic
surgery,cardiology,gastroenterology,neurosurgery,oralsurgery,ophthalmology,otolaryngology,
orthopedicsurgery,plasticsurgery,podiatry,pulmonology, radiation oncology], transplant
surgery], urology, and vascular surgery.Thanks to the different benefits that this technology
could induce in the field, the main direct applications of 3D printing in the medical and
clinical field are Used for personalized presurgical/treatment and for preoperative planning.
This will lead to a multistep procedure that, integrating clinical and imaging information, will
determine the best therapeutic option. Several studies have demonstrated that patient-specific
presurgical planning may potentially reduce time spent in the operating room (OR) and result
in fewer complications. Moreover, this may lead to reduced postoperative stays, decreased
reintervention rates, and lower healthcare costs. The 3D-printing technology allows to provide
to the surgeon a physical 3D model of the desired patient anatomy that could be used to
accurately plan the surgical approach along with cross-sectional imaging or, alternatively,
modeling custom prosthetics (or surgical tool) based on patient-specific anatomy. In this way,
a better understanding of a complex anatomy unique to each case is allowed. Furthermore, the
3D printing gives the possibility to choose before the implantation the size of the prosthesis’s
components with very high accuracy. Customize surgical tools and prostheses: the 3D printing
can be used to manufacture custom implants or surgical guides and instruments. Therefore,
the customization of surgical tools and prostheses means a reduction of cost given by the
additive manufacturing technique. Study of osteoporotic conditions: following a
pharmacological treatment, 3D printing is useful in validating the results achieved by the
patient. This enables a more accurate estimation of patient’s bone condition and a better
decision on the surgical treatment. Testing different device in specific pathways: a clear
example is the reproduction of different vascular patterns to test the effectiveness of a
cardiovascular system used to treat peripheral and coronary artery disease. In this way, the 3D
printing enables us to quickly produce prototypes of new design concepts or improvements to
14. 8
existing devices. Improving medical education: 3D-printed patient-specific models have
demonstrated that they can increase performance and foster rapid learning, while significantly
ameliorating the knowledge, management, and confidence of the trainees regardless of the
area of expertise. The benefits of 3D printing in education are the reproducibility and safety of
the 3D-printed model with respect to the cadaver dissection, the possibility to model different
physiologic and pathologic anatomy from a huge dataset of images, and the possibility to
share 3D models among different institutions, especially with ones that have fewer resources.
3D printers that have the capability to print with different densities and colors can be used to
accentuate the anatomical details.
3.1 Hearing Aids
Much too many people's surprise hearing aids are one of the greatest success stories to come
from the continued development of AM. Over 10,000,000 people are now wearing 3D printed
hearing aids with 97% of all hearing aids globally now being created using AM. Not only has
AM technology significantly reduced the cost of custom hearing aids when compared to
traditional manufacturing but the ability to produce the complex and organic surfaces required
for a hearing aid has reduced returns because of bad fit from 40% to 10%.
Fig. 3.1 Hearing Aids
Limitations
Some of limitations of AM when applied to the medical industry include:
While time to print parts is often much faster when compared to traditional manufacturing
methods there is still significant time required for the conversion of scan data to produce a
15. 9
printable STL file. Because of this, for more urgent cases like trauma surgery, generic
implants or medical devices may be a more desirable solution.
While the purchase of a desktop FDM or SLA machine typically ranges from $1000 - $5000,
high-end AM printers (SLS, material jetting and metal printing) range from $200,000 to
$850,000. Materials for these AM technologies are also currently very expensive. Currently,
for these technologies, the optimal solution is to get products made out of house.
A sound understanding of each AM technology is critical and needs to be determined within
the context of the desired outputs. Each technology has strengths and weaknesses and the
variation in price to get parts made can be significant.
3.2 Surgical Guides and Tools
Much like a drill jig is used in manufacturing to ensure a hole is placed in the exact right
location; physicians also implement guides and tools to assist in surgery. Historically, surgical
guides and tools were generic devices made of titanium or aluminum. By implementing AM,
physicians are able to create guides that precisely follow a patient's unique anatomy,
accurately locating drills or other instruments used during surgery. AM guides and tools are
used to make the placement of restorative treatments (screws, plates, and implants) more
precise, resulting in better postoperative results.
Fig. 3.2 Surgical Tools
Orthopedic surgeons and craniofacial (cranium and face) surgeons are one of the most regular
users of AM guides and tools. In 2014, 23 custom surgical guides and templates were
fabricated to assist partial or total knee replacement surgeries, more than 112 surgical guides
were fabricated to assist various craniofacial surgeries and nine different titanium alloy Ti-
6Al-4V craniofacial implants were surgically implanted into patients in Egypt alone. Surgical
16. 10
guides, derived from patient scans to precisely match their anatomy and made from PC-ISO (a
sterilizable FDM plastic), are compatible with human tissue for short-term contact. This
allows them to be placed against the patient’s anatomy for a more precise cut or drill hole.
Fig.3.3 Surgery Tools
Anatomical models (bone models) and surgical guides are also regularly both produced via
AM and used collaboratively to plan and test the best locations for stabilizing screws or plates
that conform to the patient’s bone surface before performing surgery.
3.3 Prosthetics
In the United States alone, close to 200,000 amputations are performed each year, with
prosthetics priced from $5,000-$50,000 replacement or alterations can be time consuming and
expensive. Because prosthetics are such personal items, each one has to be custom-made or fit
to the needs of the wearer. AM technology is now regularly being used to produce patient
specific components of prosthetics that match perfectly with the user's anatomy. The ability to
produce complex geometries from a range of materials has resulted in AM being adapted at
the locations where prosthetics are in contact with a patient. AM technology has been used to
produce everything from prosthetic leg connections that fit comfortably onto a user through to
a complex and highly customized facial prosthetic for a cancer patient.AM is also being used
in the manufacture of low-cost prosthetics. The collaborative nature of the AM industry has
meant that a quick internet for 3D printed prosthetics reveals a huge range of peer-reviewed
products that can be printed on desktop AM printers at a very low cost. These designs can
easily be scaled or altered to perfectly match the size of the user. The e-NABLE
Community comprises of a group of individuals from all over the world who are using their
3D printers to create free 3D printed hands and arms for those in need of an upper limb
17. 11
assistive device. Concepts like this are now becoming more commonplace as AM continues to
move into the mainstream.
Fig. 3.4 Prosthetics Legs
Typically, traditional manufacturing techniques and materials are used to produce the
structural section of functional prosthetics. AM is often then implemented at the interface
section by producing complex contours that fit perfect to the users' anatomy improving
comfort and fit. AM is also implemented on the external outer surface of prosthetics to
produce life-like and organic outer shells that hide the mechanical nature of prosthetics. This
also allows the wearer to fully customize their prosthetics to whatever design or style they
prefer.
3.4 Surgical Learning Tools
While much of the focus for 3D printing in the medical industry has been around implants and
medical devices used by patients, one of the largest areas of application has concentrated on
anatomical replicas. Historically, clinical training, education, and device testing have relied on
the use of animal models, human cadavers, and mannequins for hands-on experience in a
clinical simulation. These options have several deficiencies including limited supply, expense
of handling and storage, the lack of pathology within the models, inconsistencies with human
anatomy, and the inability to accurately represent tissue characteristics of living humans.
Physicians are now using models produced by AM from patient scan data to improve the
18. 12
diagnosis of illnesses, elucidate treatment decisions, plan, and, in some cases, even practice
selected surgical interventions in advance of the actual treatments. The models help
physicians understand patient anatomy that is difficult to visualize, especially when using
minimally invasive techniques. Models also assist in accurately sizing medical devices.
Physicians can also use the models to explain an upcoming surgery to patients and their
families and to communicate the surgical steps to the clinical team.
Fig. 3.5 Model of Patient Heart
To help reduce cost some facilities have developed procedures where surgeons practice and
plan operations on low cost mannequins that are transplanted with patient-specific AM
models. This coupled with the fact that AM technologies are able to produce both hard and
soft materials in a single part, allowing the accurate replication of human tissue, calcification,
and bone, means that surgeons can now obtain an even better understanding of exactly how a
procedure needs to be performed right down to the touch and feel of the different parts of a
patient's anatomy.
19. 13
3.5 Implants
AM’s ability to produce fine mesh or lattice structures on the surface of surgical implants can
promote better osseointegration and reduce rejection rates. Biocompatible materials such as
titanium and cobalt– chrome alloys are available for applications in maxillofacial (jaw and
face) surgery and orthopedics. The superior surface geometry produced by AM has been
shown to improve implant survival rate by a factor of 2 when compared to traditional
products. The porosity of these AM products coupled with the high level of customization and
ability to manufacture them from traditional medical materials has resulted in AM implants
becoming one of the fastest growing segments of the AM medical industry.
Fig. 3.6 Hip Replacement Sockets
Technology Best suited for
Metal printing Very high accuracy and strength and able to
Produce very complex geometries that accurately
Match to the contours of a patient's anatomy.).
Uses common medical metals (titanium and
Aluminum Porous surfaces and intricate scaffolds
are able to be printed.
20. 14
3.6 Anatomy of Patient
Eindhoven’s University of Technology is home to PhD candidate and Healthcare Flagship
Program participant, Mark Thielen, who is aiming to increase surgical and procedural success
for neonatal patients. Using 3D printing and 3D Hubs, Mark has developed an optimized
training experience using lifelike newborn models with functional organs capable of
intelligent sensor feedback.
Fig. 3.7 Model of Anatomy of Patient
For surgeons and nurses, interacting with anatomical models is important to the success of
surgeries and medical procedures. Within the neonatal field, it’s incredibly difficult to practice
correctly with the current state of practice mannequins which lack the complexity and feel of a
newborn patient. Mark’s research is to develop mannequins which have all their major
internal organs functioning and equipped with sensors to monitor key measurements such as
pressure, stress and impact during trial procedures (e.g. CPR, intubation).3D printing is
utilized because of the vast materials available for testing and, most importantly, the organic
shapes the technology is able to create. There are two key components to the mannequin: the
ribcage/spine, which acts as the housing for the second component, the internal organs. The
21. 15
sheer complexity of human anatomy is very hard to recreate realistically with any other
production method as well as increased cost and lead times. Testing was initially done with
various thermoplastic elastomers on a desktop FDM 3D printer to create the larger parts of the
model such as the rib cage. After finalizing on a design, Selective Laser Sintering (SLS) was
used because of the accuracy and dimensional freedom the technology offers. To create the
functional organs material jetting 3D printing was used to create molds. When compared to
traditional manufacturing methods, 3D printed molds allowed for rapid design changes.
Material jetting also allowed the combination of materials (rigid and flexible plastics) when
creating the molds. A heart, for example, needed to have highly detailed working valves. Due
to the extremely small sizes of neonatal organs, as well as their minuscule detail, the only way
to create a mold for these parts was to 3D print them.
3.7 Bandages
Severe burns or other wounds that penetrate many layers of skin are difficult to heal. In fact,
in some developing countries, infections from serious wounds can be fatal. This is the main
reason why 3D printed bandages came into existence. Compared to their conventional
counterparts, 3D printed bandages offer a number of advantages. Some of the key benefits
include customizing bandages to particular wounds, infusing the material with special
substances, and increasing accessibility in developing or war-torn parts of the world. One
fascinating example comes from a team of students at Grand Canyon University. They
developed a low-cost, 3D printed hydro-colloidal bandage, which aids in treating infections
more effectively than a regular one.
Fig. 3.8 Bandages
22. 16
Essentially, it’s partially composed of a gel-like substance that sucks in and traps bacteria.
According to Geek, researchers at the University of Toronto built a 3D imprinter, called Print
alive, which could print living bandages. This 3D printed band-aid both heals the wound and
grows into and around the surrounding skin.
23. 17
CONCLUSION
The 3D printing in medical field and design needs to think outside the norm for changing the
health care. The three main pillars of this new technology are the ability to treat more people
where it previously was not feasible, to obtain outcomes for patients and less time required
under the direct case of medical specialists. In few words, 3D printing consists in “enabling
doctors to treat more patients, without sacrificing results”. Therefore, like any new
technology, 3D printing has introduced many advantages and possibilities in the medical field.
Each specific case in which 3D printing has found application shown in this analysis is a
demonstration of this. However, it must be accompanied by an updated and current legislation
in order to guarantee its correct use.3DP is widely used in healthcare. The domain of hearing
aids is the first manufacturing branch fully overtaken by 3DP, and dentistry seems to be
following suit. Implants and prostheses, the application of models in virtual surgical planning
and teaching in healthcare, traditional and novel medical devices, 3DP of drugs – all these are
rapidly developing areas of the 3DP applications in medicine. In most fields they offer
considerably less expensive alternatives to the classical devices and procedures, release
creativity accelerated by the ease of prototyping of novel devices and help through diagnostics
and medical procedures. Think about the effect of virtual surgical planning or that of
inexpensive limb prostheses presented above. An important feature of 3DP is its contribution
to personalized medicine. According to Wikipedia, “the term has risen in usage in recent years
given the growth of new diagnostic and informatics approaches that provide understanding of
the molecular basis of disease, particularly genomics”. One could call it personalized
medicine on the nanoscale. 3DP offers personalized medicine on the macro scale, since
implants and prostheses and numerous devices for medical use are patient-specific.
Apart from the tissue model exVive3D Liver developed by Organovo; 3D imprinting is still in
the development phase, since 3D imprinter organs are beyond our reach. But it certainly will
bring revolutionary changes in medicine. Introduction of new (bio) printers and (bio)
compatible materials will accelerate medical applications of 3DP.
24. 18
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