complete description of tobacco cessation, NRT etc

1. TOBACCO CESSATION
PROGRAMME
1
CHAITANYA.P
II MDS
Dept of Public Health Dentistry

2. PREVIOUS QUESTIONS
• Tobacco cessation Counselling. Apr2012, Oct
2013.
2

3. CONTENTS:
• Introduction to Tobacco.
• Tobacco production in India.
• Tobacco cessation clinics in India.
• Global adult Tobacco survey(GATS).
• Behavioural counselling for cessation.
• Fagerstrome scale for smokers and non -smokers.
• Prochaska diclemente model.
• Nicotine replacement therapy
• Pharmacotherapy
• Studies related to success of tobacco cessation.
• References.
3

4. TOBACCO
• Plant: Nicotiana
• Family: Solanaceae.
• Geographical origin: North America
• Ingredients: Nicotine.
• Species: N. tabacum
4

5. 5

6. 6
http://www.mapsofworld.com/world-top-ten/tobacco-producing-countries.html Last
accessed on 28/03/2016.
2012

7. 7
LIST OF COUNTRIES BY CIGARETTE CONSUMPTION PER CAPITA
https://en.wikipedia.org/wiki/List_of_countries_by_cigarette_consumption_per_capita Last
accessed on 28/03/2016.

8. The Global Adult Tobacco Survey (GATS) is a
nationally representative household survey
that was launched in February 2007
16 low- and middle-income countries where
more than half of the world’s smokers live and
that bear the highest burden of tobacco use
TOPICS FOCUSED:
Tobacco use prevalence
Second-hand tobacco smoke exposure and
policies
 Cessation
Knowledge, attitudes and perceptions
Exposure to media
Economics
Bangladesh,
Brazil, China,
Egypt, India,
Indonesia,
Mexico,
Pakistan,
Philippines,
Poland,
Russian
Federation,
Thailand,
Turkey,
Ukraine,
Uruguay and
Viet Nam. 8

9. • Global Adult Tobacco Survey (GATS) in 2010
revealed that
47.9% of males
20.3%of females,
34.6% of the adult
used tobacco in one or the other form in India
9

10. 10

11. Source:- Global adult survey report 2010, Union Ministry of Human Health and
Family Welfare INDIA 11

12. How people develop dependence to tobacco?
12

13. 13
On Oral cavity

14. 14
Oral Lesions and Conditions Related to Tobacco Use

15. 15
Potential Negative Impact on Periodontal Tissues from Smoked
Tobacco
• Change in vasculature – reducing immune response.
• Suppression of hemorrhagic responsiveness(bleeding).
• Reduction of oxygen in the periodontal pocket – affecting composition of
subgingival flora.
• Interference with cytokine production – inhibiting the immune response.
• Increase in proteolytic enzymes – leading to periodontal destruction.
• Compromised PDL attachment to root surface – poor healing following
periodontal therapy.
• Decrease in lymphocyte production.

16. 16
http://www.theguardian.com/news/datablog/2012/mar/23/tobacco-industry-atlas-smoking
Last accessed on 28/3/2016

17. TOBACCO CESSATION CLINICS
2002
5 centers are established.
Later it reached to 18 centers.
17

18. 18

19. • Concept and operational plan was prepared by technical experts
from three premier institutions.
19
Institute of Human Behaviour and
Allied sciences, Delhi
Postgraduate institute of Medical Education and Research, Chandigarh
National Institute of Mental health and
Neurosciences, Bangalore

20. In the first 5 yrs of tobacco cessation
clinic establishment.
34741 cases were
registered.
69% - behavioral
strategies
employed.
31%-
pharmacotherapy+
Behavioral
counseling.
20
Murthy P, Saddichha S; Tobacco cessation services in India: Recent
developments and the need for expansion Indian Journal of Cancer, 2010,
Volume 47,Suppl 1 .

21. 21
Three Components for Tobacco Cessation

22. ARRANGE
5 A’S
22

23. • Ask - Identify and document tobacco use status for every patient at every visit.
(You may wish to develop your own vital signs sticker, based on the sample
below).
• Advise - In a clear, strong, and personalized manner, urge every tobacco user
to quit.
• Assess - Is the tobacco user willing to make a quit attempt at this time?
• Assist - For the patient willing to make a quit attempt, use counseling and
pharmacotherapy to help him or her quit
• Arrange - Schedule follow up contact, in person or by telephone, preferably
within the first week after the quit date.
23

24. PATIENTS WHO
ARE UNWILLING
TO QUIT TOBACCO
5 R’S
24

25. FAGERSTROME SCALE
25

26. Fagerstrom scale for nicotine
dependence - smoking
26

27. MAX SCORE = 10 27
1. How soon after you wake up do you smoke your first cigarette?
3-within 5 minutes
2- 6-30 minutes
1- 31-60 minutes
0- After 60 minutes
2. Do you find it difficult to refrain from smoking in places where it is forbidden (eg.in church,
at the library, cinema etc.)?
1-Yes
0- No
3. Which cigarette would you hate to give up most?
1- The first one in the morning
0-All the others
4. How many cigarettes/day do you smoke?
0- 10 or less
1- 11-20
2- 21-30
3- 31 or more
5. Do you smoke more frequently during the first hour after waking than during the rest of the
day?
1-Yes 0- No
6. Do you smoke if you are so ill you are in bed most of the day?
1- Yes 0-No
Fagerstrom test for Nicotine Dependence(FTND) and Heaviness of Smoking(HIS)

28. Scores on
Fagerstrom test
Level of Dependence First line of
Treatment
Second Line of
Treatment
0 to 2 Very low Dependence Psychological or
Behavioral
Intervention
3 to 5 Medium Dependence Psychological or
Behavioral
Intervention
NRT(2mg)
(Nutritional
supplement)
6 to 7 High Dependence NRT(2mg) along
with
Psychological or
Behavioral
Intervention
NRT(4mg)
Above 8 Very High Dependence NRT(4mg) along
with
Psychological or
Behavioral
Intervention
Pharmacological
intervention
28

29. 29

30. MAX SCORE = 10 30
Fagerstrom test for Nicotine Dependence – Smokeless tobacco(FTND –ST)
1. How soon after you wake up do you place your first dip?
3-within 5 minutes
2- 6-30 minutes
1- 31-60 minutes
0- After 60 minutes
2. How often do you intentionally swallow tobacco juice?
2-Always
1-Sometimes
0- Never
3. Which chew would you hate to give up most?
1- The first one in the morning
0-Any other
4. How many can/pouches per week do you use?
2- More than 3
1- 2-3
0- 1
5. Do you chew more frequently during the first hour after awakening than during the rest of
the day?
1-Yes 0- No
6. Do you chew if you are so ill you are in bed most of the day?
1- Yes 0-No

31. 31
Scores on
Fagerstrom test
Level of Dependence First line of
Treatment
Second Line of
Treatment
0 to 4 Very low Dependence Psychological or
Behavioral
Intervention
5 to 8 Medium Dependence Psychological or
Behavioral
Intervention
NRT(2mg)
(Nutritional
supplement)
9 to 10 High Dependence NRT(2mg) along
with
Psychological or
Behavioral
Intervention
NRT(4mg)
Above 10 Very High Dependence NRT(4mg) along
with
Psychological or
Behavioral
Intervention
Pharmacological
intervention

32. Prochaska and Diclemente
The Transtheoretical Model (TTM)
(1983)
32

33. 33
http://www.prochange.com/transtheoretical-model-of-behavior-change last
accessed on 28/3/2016

34. 34
Stage of Readiness Patient Response to: “What
are your thoughts and feelings
about Quitting smoking?”
Goal of
intervention
Typical Physician
Intervention
Precontemplation “I like to smoke” Introduce
ambivalence
“Your emphysema will
improve after you quit
smoking”
Contemplation “I like to smoke, but I know I
need to quit”
Resolve
ambivalence
“How will your life be
better after you’ve quit
smoking?”
Preparation “I’m ready to quit” Identify
successful
strategies
“Choose a ‘quit day’ and
let’s make plans for it”
Action “I’m not smoking, but I still think
about smoking from time to
time”
Provide
solutions to
specific relapse
triggers
“How can you deal with
your desire to smoke in
those situations?”
Maintenance “I used to smoke” Solidify
patient’s
commitment
to a smoke
free life
“This would be a good
time to share your
experience with other
people”
Summary of physician counselling based on the stages of change

35. NICOTINE REPLACEMENT THERAPY
35

36. NICOTINE REPLACEMENT THERAPY(NRT)
36

37. 37

38. 2 mg (< 25 cigarettes/day)
4 mg (≥ 25 cigarettes/day)
User controls dose
• Oral substitute for cigarettes
• Available without prescription
Disadvantages:
Difficult for denture wearers to use
side effects:
•Mouth irritation
•Stomach ache
• Sore jaw
• Nausea
• Hiccups 38

39. urge to smoke Within 30 min after wake up
Urge to smoke no sooner than 30 min
9–20 lozenges/day during first 6 weeks, then
decrease dose gradually until treatment is
stopped
Advantages:
•Easy to use
• Oral substitute for cigarettes
• Available without prescription
Adverse effects:
•Insomnia
• Nausea
• Hiccups
• Coughing
39

40. •Easy to use
• Unobtrusive
• Available without
prescription.
Disadvantages:
•User cannot adjust dose if craving
occurs
• Nicotine released more slowly
than in other products
Adverse effects:
•Skin irritation
• Insomnia
40

41. •User controls dose
• Hand-to-mouth substitute for
cigarettes
Disadvantages;
•Frequent puffing needed
• Device visible when
used
Adverse effects:
•Mouth and throat irritation
• Cough
• Rhinitis
41

42. dosage:1–2 doses/hr(1 mg total; 0.5
mg in each nostril)
(maximum, 40 mg/day)
•User controls dose
• Offers most rapid delivery of nicotine and
highest nicotine levels of all nicotine
replacement products.
Adverse effects:
•Nasal irritation
• Sneezing
• Cough
• Tearing
42

43. Pharmacotherapeutic approach
43

44. 44
Bupropion SR 1-2 wks before quit
date
150mg/d for 3days,
then 150mg bid for
7-12wks
May continue use
for 6mon after quit
date

45. 45
Varenicline 1wk before quit
date
0.5mg/d for 3d;
then 0.5mg bid for
4d; then 1.0mg bid
for 3mon
May continue use
for 6

46. Recommended:-75–100 mg/day
Treatment should be started 10–28 days
before the quit date at a dose of 25 mg/day;
the dose should be increased as tolerated.
Side effects:
•Dry mouth
• Sedation
• Dizziness
• Tremor
Nortriptyline is a tricyclic anti‐depressant .It has a sedative effect
which helps to improve sleep
46

47. Studies – success of tobacco cessation
47

48. • A real-life study of the effectiveness of different pharmacological approaches
to the treatment of smoking cessation: re-discussing the predictors of success
• Study place: University of Sao PauloMedical School, brazil.
836 – smokers.
25 cigarettes/day
Fagerstrome Score - 6.6.
Result:
tobacco cessation teaching in hospital has higher
success rates.
Nortriptyline + NRT Higher success rates(46.4%).
48
Gustavo Faibischew Prado, Elisa Maria Siqueira Lombardi, Marco Anto nio
Bussacos,Frederico Leon Arrabal-Fernandes, Ma´rio Terra-Filho, Ubiratan de Paula Santos;
A real-life study of the effectiveness of different pharmacological approaches to the
treatment of smoking cessation: re-discussing the predictors of success; CLINICS
2011;66(1):65-71

49. Settings and Design: This is a community based tobacco cessation program
of one year duration conducted among women in a low socioeconomic area
of Mumbai, India.
Subjects and Methods: It involved three interventions conducted at three
months interval, comprised of health education, games and counseling
sessions and a post intervention follow up.
49
• Tobacco use among family members and in the
community was primary reasons for initiation
and addiction to tobacco was an important
factor for continuation, whereas health
education and counseling seemed to be largely
responsible for quitting. The quit rate at the end
of the programme was 33.5%.
GA Mishra, SV Kulkani, Majumdar PV, SD Gupta, SS Shastri; Community-based
tobacco cessation program among women in Mumbai, Indian Journal of Cancer, Dec
2014, Volume 51, supplement 1

50. • AIMS:
• To assess the tobacco quit rates among employees, through self report history, and validate it
with rapid urine cotinine test; compare post-intervention KAP
regarding tobacco consumption with the pre-intervention responses and assess
the tobacco consumption pattern among contract employees and provide assistance to
encourage quitting.
• SETTINGS AND DESIGN:
• This is a cohort study implemented in a chemical industry in rural Maharashtra, India.
• MATERIALS AND METHODS:
• All employees (104) were interviewed and screened for oral neoplasia. Active intervention in
the form of awareness lectures, focus group discussions and if needed, pharmacotherapy
was offered. Medical staff from the industrial medical unit and from a local referral hospital
was trained. Awareness programs were arranged for the family members and contract
employees.
• RESULTS:
• Forty eight per cent employees consumed tobacco. The tobacco quit rates increased with
each follow-up intervention session and reached 40% at the end of one year. There was 96%
agreement between self report tobacco history and results of rapid urine cotinine test. The
post-intervention KAP showed considerable improvement over the pre-intervention KAP. 56%
of contract employees used tobacco and 55% among them had oral pre-cancerous lesions.
• CONCLUSIONS:
• A positive atmosphere towards tobacco quitting and positive peer pressure assisting each
other in tobacco cessation was remarkably noted on the entire industrial campus. A
comprehensive model workplace tobacco cessation program has been established, which can
be replicated elsewhere.
50
GA Mishra, SV Kulkani, Majumdar PV, SD Gupta, SS Shastri;
Workplace tobacco cessation program in India: A success story. Indian Journal of
Occupational and Environmental Medicine; December 2009, Volume 13, Issue 3.

51. World No Tobacco Day 2016: Get
ready for plain packaging
packaging of tobacco products is an important demand reduction
measure. It reduces the attractiveness of tobacco products, restricts
use of tobacco packaging as a form of advertising, limits misleading
packaging and labelling, and increases the effectiveness of health
warnings.
For World No Tobacco Day, 31 May 2016, WHO and the Secretariat
of the WHO Framework Convention on Tobacco Control are calling
on countries to get ready for plain (standardized) packaging of
tobacco products.
http://www.who.int/campaigns/no-tobacco-day/2016/en/. Last accessed on 28/03/2016. 51

52. Barriers of tobacco cessation
• The lack of training and sensitization of health
professionals limits the assessment and
intervention of tobacco use.
52

53. Lack of trained health professionals to
provide quitting support
53

54. Lack of knowledge of ill effects of tobacco.
54

55. 55

56. References
1. Daly & bachelor,Richard Watt – Essential Dental Public Health.
2. Esther v Wilkins – clinical practice for dental hygienist.
3. Prochaska JO, DiClemente CC. Toward a comprehensive model of change.
In: Miller WR, Heather N, eds. Treating addictive behaviors: processes of
change. New York: Plenum, 1986:3–27.
4. Clinical practice. Treatment of tobacco use and dependence. N Engl J Med
2002;346:506-512.
5. Murthy P, Saddichha S; Tobacco cessation services in India: Recent
developments and the need for expansion;Indian Journal of Cancer,
2010;Volume 47 ;Suppl 1
6. WHO – GLOBAL ADULT TOBACCO SURVEY (GATS)-2007.
56

57. 7. GA Mishra, SV Kulkani, Majumdar PV, SD Gupta, SS Shastri; Community-based
tobacco cessation program among women in Mumbai, Indian Journal of Cancer,
Dec 2014, Volume 51, supplement 1
8. GA Mishra, SV Kulkani, Majumdar PV, SD Gupta, SS Shastri;
Workplace tobacco cessation program in India: A success story. Indian Journal of
Occupational and Environmental Medicine; December 2009, Volume 13, Issue 3.
9. Cherian Varghesea ; Initiating tobacco cessation services in India: challenges
and opportunities;WHO South-East Asia Journal of Public Health 2012;1(2):159-
168 .
10. Krishna M. Palipudi, Prakash C. Gupta, Dhirendra N. Sinha, Linda J. Andes,
Samira Asma, Tim McAfee, on behalf of the GATS Collaborative Group; Social
Determinants of Health and Tobacco Use in Thirteen Low and Middle Income
Countries: Evidence from Global Adult Tobacco Survey; Plos one; March 2012,
Volume 7, Issue 3,e33466 57

58. 11. http://www.who.int/campaigns/no-tobacco-day/2016/en/. Last accessed on
28/03/2016.
12. Brian A King, Sara A Mirza, Stephen D Babb, and for the GATS
Collaborating Group; A cross-country comparison of second hand smoke
exposure among adults: findings from the Global Adult Tobacco Survey
(GATS); Tob Control. 2013 July ; 22(4): e5.
13. Gustavo Faibischew Prado, Elisa Maria Siqueira Lombardi, Marco Anto
nio Bussacos,Frederico Leon Arrabal-Fernandes, Ma´rio Terra-Filho, Ubiratan
de Paula Santos; A real-life study of the effectiveness of different
pharmacological approaches to the treatment of smoking cessation: re-
discussing the predictors of success; CLINICS 2011;66(1):65-71.
58

59. 59
14.http://www.mapsofworld.com/world-top-ten/tobacco-producing countrieshtml.
Last accessed on 28/03/2016.
15.https://en.wikipedia.org/wiki/List_of_countries_by_cigarette_consumption_
per_capita Last accessed on 28/03/2016.
16. Norman O. Harris; Primary Preventive Dentistry, 7th Edition, 2009, Julie Levin
Alexander publishers.
17. http://www.theguardian.com/news/datablog/2012/mar/23/tobacco-industry-
atlas-smoking Last accessed on 28/3/2016

60. 60