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Eukaryotic &
Prokaryotic Cells
Horace Juberry Chikagwa
hchikagwa@mubas.ac.mw
4-Feb-24
2
hj
Eukaryotes
•Greek;“Eu” – true / good,“karyon” – kernel.
•Complex for survival.
•Include protozoa, fungi, plantae, animalia.
4-Feb-24
3
hj
Eukaryotic Cells
• Clearly defined nucleus.
• Double enveloped nucleus housing chromosomes.
• Other organelles:
•Mitochondria – ATP generation
•Golgi apparatus – secretory entity
•ER (SER & RER) – intracellular pathway
•Lysosomes – digestive machinery
4-Feb-24
4
hj
Eukaryotic and Prokaryotic Cells
4-Feb-24
5
hj
Prokaryotic Cells
•Greek;“pro” – before.“karyon”: - kernel
•Lack distinct nuclei.
•Lack organelles too due to lack of internal
membranes.
•Best example; bacteria.
4-Feb-24
6
hj
Prokaryotic Cells
4-Feb-24
7
hj
Eukaryotic vs Prokaryotic Cells
Eukaryotic Cell Prokaryotic Cells
Nucleus Present, double membraned Absent, only nucleoid region
Cell type Multi – or unicellular Always unicellular
Cell division Mitosis Binary fission
flagella large Small
Cell wall Simple in nature if present Present and complex
Lysosome Present Absent
Mitochondria Present Absent
Endoplasmic reticulum Present Absent
DNA linear Circular
Ribosomes Larger, linear Smaller, spherical
Reproduction Both sexual and asexual Asexual only
Plasmids Present Rare
4-Feb-24
8
hj
Nucleus
• Spherical or oval, most prominent feature.
• Cells may have one or more.
• Some cells lack nuclei e.g. RBCs.
• Double membrane (nuclear envelope) separates it from
cytoplasm.
• Outer membrane is continuous with RER.
• Small molecules and ions pass through nuclear pores.
• Large proteins and RNAs pass by active trpt.
4-Feb-24
9
hj
Nucleus Structure
4-Feb-24
10
hj
Nucleolus
•Spherical body producing ribosomes.
•Not enclosed in a membrane.
•Site of RNA synthesis, RNA and protein assembly in
ribosomal subunits.
•Disappear during cell division.
•Reorganize once cells are formed.
4-Feb-24
11
hj
Chromosomes
• Thread-like structures in the
nucleus.
•Not visible when cell not
dividing.
• Constriction divides
chromosome into:
i. p arm: short section
ii. q arm: long section.
4-Feb-24
12
hj
Chromosomes
•Made of DNA
coiled around
protein called
histone.
•DNA, proteins and
some RNAs form
chromatin.
4-Feb-24
13
hj
Linker DNA
Chromosomes
4-Feb-24
14
hj
Not entirely correct
Newly synthesized DNA is packed into
condensed chromatin fibers
Basic packing unit is nucleosome
(147 bp + 8 histones)
Five types of histones synthesized in S-
phase
-H1 (linker), -H2A, H2B, -H3,-H4
Basic Chromatin Structure
4-Feb-24
15
hj
THANK YOU
4-Feb-24 16
hj

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1. Prokaryotic and Eukaryotic Cells ppt.pdf

  • 1. Eukaryotic & Prokaryotic Cells Horace Juberry Chikagwa hchikagwa@mubas.ac.mw
  • 3. Eukaryotes •Greek;“Eu” – true / good,“karyon” – kernel. •Complex for survival. •Include protozoa, fungi, plantae, animalia. 4-Feb-24 3 hj
  • 4. Eukaryotic Cells • Clearly defined nucleus. • Double enveloped nucleus housing chromosomes. • Other organelles: •Mitochondria – ATP generation •Golgi apparatus – secretory entity •ER (SER & RER) – intracellular pathway •Lysosomes – digestive machinery 4-Feb-24 4 hj
  • 5. Eukaryotic and Prokaryotic Cells 4-Feb-24 5 hj
  • 6. Prokaryotic Cells •Greek;“pro” – before.“karyon”: - kernel •Lack distinct nuclei. •Lack organelles too due to lack of internal membranes. •Best example; bacteria. 4-Feb-24 6 hj
  • 8. Eukaryotic vs Prokaryotic Cells Eukaryotic Cell Prokaryotic Cells Nucleus Present, double membraned Absent, only nucleoid region Cell type Multi – or unicellular Always unicellular Cell division Mitosis Binary fission flagella large Small Cell wall Simple in nature if present Present and complex Lysosome Present Absent Mitochondria Present Absent Endoplasmic reticulum Present Absent DNA linear Circular Ribosomes Larger, linear Smaller, spherical Reproduction Both sexual and asexual Asexual only Plasmids Present Rare 4-Feb-24 8 hj
  • 9. Nucleus • Spherical or oval, most prominent feature. • Cells may have one or more. • Some cells lack nuclei e.g. RBCs. • Double membrane (nuclear envelope) separates it from cytoplasm. • Outer membrane is continuous with RER. • Small molecules and ions pass through nuclear pores. • Large proteins and RNAs pass by active trpt. 4-Feb-24 9 hj
  • 11. Nucleolus •Spherical body producing ribosomes. •Not enclosed in a membrane. •Site of RNA synthesis, RNA and protein assembly in ribosomal subunits. •Disappear during cell division. •Reorganize once cells are formed. 4-Feb-24 11 hj
  • 12. Chromosomes • Thread-like structures in the nucleus. •Not visible when cell not dividing. • Constriction divides chromosome into: i. p arm: short section ii. q arm: long section. 4-Feb-24 12 hj
  • 13. Chromosomes •Made of DNA coiled around protein called histone. •DNA, proteins and some RNAs form chromatin. 4-Feb-24 13 hj Linker DNA
  • 14. Chromosomes 4-Feb-24 14 hj Not entirely correct Newly synthesized DNA is packed into condensed chromatin fibers Basic packing unit is nucleosome (147 bp + 8 histones) Five types of histones synthesized in S- phase -H1 (linker), -H2A, H2B, -H3,-H4