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Writing and implementation of
guidelines, story in between
and practical advices
Prof. Dr. Jens Meier
Clinic for Anesthesiology and Critical Care Medicine
Kepler University Linz
Which care do we want to deliver?
patient
satisfaction
high medical
and nursing
quality
economical
and effective
optimized
processes
The standard of care in transfusion
Which care do we want to deliver?
patient
satisfaction
high medical
and nursing
quality
economical
and effective
optimized
processes
Do you achieve this
in PBM?
Overconfidence
Are you an above average lover?
> 75 % yes
< 25 % no
Are there any differences?
The situation in my country
Gombotz, Transfusion, 2007
Knowledge transfer
Gombotz, Transfusion, 2014
Center
before PBM implementation
after PBM implementation
Transfusion policy is like...
What creates this diversity?
9 types of procedural
nonadeherence
• No perception of relevant information (input)
• Misperception of information (pattern matching)
• Procedural design (input, interpretation)
• Procedural experience/training (long-term memory)
• Cultural aspects (influencing factors)
• Personality aspects/attitudes (influencing factors)
• Situational factors (influencing factors)
• Decision-making heuristics (decision making)
• awareness and attention management
Types of violations
• routine violations: common practice becoming group norm
• optimizing violations: challenge when rules are too
restrictive
• situational violations: dictated by immediate environment
• exceptional violations: unusual or unfamiliar circumstances
Individualism?
I know better?
There is urgency for a guideline
Why do we need guidelines?
• Overwhelming amount of the literature
• Inadequacy of textbooks
• Difficulty synthesizing evidence and
translating into practice
What makes a good guideline?
• Valid
• Reproducible
• Cost-effective
• Representative / multidisciplinary
• Clinically applicable
• Flexible
• Clear
• Reviewable
• Amenable to clinical audit
How are evidence-based
guidelines developed?
• Identifying and refining the subject area of a guideline
• Running guideline development groups
• Identifying and assessing the evidence
• Translating evidence into a clinical practice guideline
• Reviewing and updating guidelines
The WHO way for guideline
development
The WHO way of a guideline
Who should write a guideline?
Professor Practitioner
• lots of theoretical knowledge
• well known
• trustable
• knows nothing about daily practice
• sponsored by industry
• good theoretical knowledge
• often unknown
• trustable ?
• knows everything about daily practice
• does not know the whole story
• sponsored by industry
The WHO way of a guideline
What is a PICO question?
What is a PICO question?
among elderly patients
does restrictive transfusion
versus liberal transfusion
affect mortality
What is a PICO question?
among elderly patients
does restrictive transfusion
versus liberal transfusion
affect mortality
among patients > 85 years
does Hb>11 g/dl
versus Hb<11g/dl
affect morbidity
The WHO way of a guideline
Grading the results
The WHO way of a guideline
Knowledge transfer
Knowledge transfer
Knowledge transfer
What are the typical steps of
guideline development
• Convert the need for info into an answerable
question
• Track down the best evidence
• Critically appraise that evidence
• Integrate the appraisal with one’s clinical
expertise and the individual patient
Critique for the guideline
process
• De-emphasizes patient values
• Doesn’t account for individual
variation
• Devalues clinical judgment
• Leads to therapeutic nihilism
Conclusions

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1 jens meier zagreb guidelines 2019 04 28

  • 1. Writing and implementation of guidelines, story in between and practical advices Prof. Dr. Jens Meier Clinic for Anesthesiology and Critical Care Medicine Kepler University Linz
  • 2. Which care do we want to deliver? patient satisfaction high medical and nursing quality economical and effective optimized processes
  • 3. The standard of care in transfusion
  • 4. Which care do we want to deliver? patient satisfaction high medical and nursing quality economical and effective optimized processes Do you achieve this in PBM?
  • 5. Overconfidence Are you an above average lover? > 75 % yes < 25 % no
  • 6. Are there any differences?
  • 7. The situation in my country Gombotz, Transfusion, 2007
  • 8. Knowledge transfer Gombotz, Transfusion, 2014 Center before PBM implementation after PBM implementation
  • 10. What creates this diversity?
  • 11. 9 types of procedural nonadeherence • No perception of relevant information (input) • Misperception of information (pattern matching) • Procedural design (input, interpretation) • Procedural experience/training (long-term memory) • Cultural aspects (influencing factors) • Personality aspects/attitudes (influencing factors) • Situational factors (influencing factors) • Decision-making heuristics (decision making) • awareness and attention management
  • 12. Types of violations • routine violations: common practice becoming group norm • optimizing violations: challenge when rules are too restrictive • situational violations: dictated by immediate environment • exceptional violations: unusual or unfamiliar circumstances
  • 14. There is urgency for a guideline
  • 15. Why do we need guidelines? • Overwhelming amount of the literature • Inadequacy of textbooks • Difficulty synthesizing evidence and translating into practice
  • 16. What makes a good guideline? • Valid • Reproducible • Cost-effective • Representative / multidisciplinary • Clinically applicable • Flexible • Clear • Reviewable • Amenable to clinical audit
  • 17. How are evidence-based guidelines developed? • Identifying and refining the subject area of a guideline • Running guideline development groups • Identifying and assessing the evidence • Translating evidence into a clinical practice guideline • Reviewing and updating guidelines
  • 18. The WHO way for guideline development
  • 19. The WHO way of a guideline
  • 20. Who should write a guideline? Professor Practitioner • lots of theoretical knowledge • well known • trustable • knows nothing about daily practice • sponsored by industry • good theoretical knowledge • often unknown • trustable ? • knows everything about daily practice • does not know the whole story • sponsored by industry
  • 21. The WHO way of a guideline
  • 22. What is a PICO question?
  • 23. What is a PICO question? among elderly patients does restrictive transfusion versus liberal transfusion affect mortality
  • 24. What is a PICO question? among elderly patients does restrictive transfusion versus liberal transfusion affect mortality among patients > 85 years does Hb>11 g/dl versus Hb<11g/dl affect morbidity
  • 25. The WHO way of a guideline
  • 27. The WHO way of a guideline
  • 31. What are the typical steps of guideline development • Convert the need for info into an answerable question • Track down the best evidence • Critically appraise that evidence • Integrate the appraisal with one’s clinical expertise and the individual patient
  • 32. Critique for the guideline process • De-emphasizes patient values • Doesn’t account for individual variation • Devalues clinical judgment • Leads to therapeutic nihilism