The AWESOME project aims to examine the health impacts of exposure to pollutant mixtures and weather now and under future climate and air quality policies through epidemiological studies. It will develop high resolution spatiotemporal models of multiple pollutants and weather, examine indoor environments, and conduct epidemiological analyses. It will also apply multi-criteria decision analysis to evaluate policies and examine socioeconomic impacts. Over the next 6-12 months it will conduct initial epidemiological analyses, further develop indoor exposure models, and obtain stakeholder input on policy priorities and the MCDA framework.