This document provides an introduction to aviation medicine and discusses the effects of altitude on the human body. It covers:
1) The layers of the atmosphere and how physical properties like temperature, pressure and gas composition change with increasing altitude.
2) Gas laws like Boyle's, Charles' and Henry's law that are relevant to understanding decompression.
3) How decreasing atmospheric pressure can cause problems in body cavities that contain gas like the middle ear, sinuses, lungs and gastrointestinal tract through expansion of trapped gases.
4) Steps that can be taken to prevent issues like equalizing cabin pressure, avoiding gas-producing foods before flying and ensuring good dental health.
Pitot Static System is hugely used in aviation sector. Even almost all modern aircrafts use this ancient technology to calculate their airspeed, altitude, and vertical speed.
The system is briefly but exquisitely presented in this slide.
042009 Science Of Climate Change: Overview For Community Organizations Dr Tes...lisa.ito
Science Of Climate Change: Overview For Community Organizations
Dr Tess Perez National Grassroots Conference on Climate Change
Balai Kalinaw, UP Diliman
20-21 April 2009
www.philclimatewatch.org
Definition, Composition of atmospheric air, Classification and sources of air
pollutants. Effects of air pollution on human, plant and material, Air pollution control methods, equipment and safety.
Pitot Static System is hugely used in aviation sector. Even almost all modern aircrafts use this ancient technology to calculate their airspeed, altitude, and vertical speed.
The system is briefly but exquisitely presented in this slide.
042009 Science Of Climate Change: Overview For Community Organizations Dr Tes...lisa.ito
Science Of Climate Change: Overview For Community Organizations
Dr Tess Perez National Grassroots Conference on Climate Change
Balai Kalinaw, UP Diliman
20-21 April 2009
www.philclimatewatch.org
Definition, Composition of atmospheric air, Classification and sources of air
pollutants. Effects of air pollution on human, plant and material, Air pollution control methods, equipment and safety.
attached document is the lecture ppt for the course Methods of Experimental Physics. it was just an introduction to the course and the course contents...
Calibration Laboratory In India - FARE Labs Pvt. Ltd.Fare Labs
Fare Labs provides India’s best calibration services all over the world, Fare Labs Calibration laboratory is an NABL-accredited Laboratory. Please visit us- https://farelabs.com/services/calibration-laboratory
Catalogue Standa Redsun thể hiện thông tin cơ bản về hình ảnh ổn áp standa 1 pha; ổn áp standa 3 pha; biến áp standa 1 pha; biến áp standa 3 pha hàng chính hãng Công ty Cổ phần Thương mại & Sản xuất Redsun sản xuất.
Propeller cavitation is a major problem in ship operation and the costs of repair and maintenance is high for ship-owners. Proper design of propeller plays a very important role in life cycle and the performance of a vessel. The use of simulation to observe various parameters that affect cavitations can be helpful to optimize propeller performance. This project designs and simulates cavitations flow of a Kaplan series, Fixed Pitch Propeller (FPP) of a 48-metres Multipurpose Deck Ship at 11 knots. Simulation test was carried out for laminar and turbulent flow using Computational Fluid Dynamics (CFD) approach to observe cavitations occurrence at selected radius. The parameters considered are pitch angle, angle of attack, viscosity of sea water, operating vapour pressure in the sea water, engine power, lift and drag vectors of each of the blade sections, and resultant velocity of the fluid flow. Comparison of performance is made and it compares well with the theory. Thrust coefficient (KT), torque coefficient (KQ), thrust (T), advance coefficient (J), and cavitations number (σ), were calculated to deduce efficiency and validate the model. The study can be used to build a prototype physical model that could be beneficial for future additional experimentation investigation.
Key words: Simulation, cavitation, performance, propeller, CFD
Exposición de José Marín, geólogo de reservorios y especialista en Geomodelación ; fue transmitida en VIVO para la comunidad del Portal de Ingeniería. Para poder ver la charla, ingresa al siguiente enlace: https://www.youtube.com/watch?v=3YJYPQWfuBM
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
attached document is the lecture ppt for the course Methods of Experimental Physics. it was just an introduction to the course and the course contents...
Calibration Laboratory In India - FARE Labs Pvt. Ltd.Fare Labs
Fare Labs provides India’s best calibration services all over the world, Fare Labs Calibration laboratory is an NABL-accredited Laboratory. Please visit us- https://farelabs.com/services/calibration-laboratory
Catalogue Standa Redsun thể hiện thông tin cơ bản về hình ảnh ổn áp standa 1 pha; ổn áp standa 3 pha; biến áp standa 1 pha; biến áp standa 3 pha hàng chính hãng Công ty Cổ phần Thương mại & Sản xuất Redsun sản xuất.
Propeller cavitation is a major problem in ship operation and the costs of repair and maintenance is high for ship-owners. Proper design of propeller plays a very important role in life cycle and the performance of a vessel. The use of simulation to observe various parameters that affect cavitations can be helpful to optimize propeller performance. This project designs and simulates cavitations flow of a Kaplan series, Fixed Pitch Propeller (FPP) of a 48-metres Multipurpose Deck Ship at 11 knots. Simulation test was carried out for laminar and turbulent flow using Computational Fluid Dynamics (CFD) approach to observe cavitations occurrence at selected radius. The parameters considered are pitch angle, angle of attack, viscosity of sea water, operating vapour pressure in the sea water, engine power, lift and drag vectors of each of the blade sections, and resultant velocity of the fluid flow. Comparison of performance is made and it compares well with the theory. Thrust coefficient (KT), torque coefficient (KQ), thrust (T), advance coefficient (J), and cavitations number (σ), were calculated to deduce efficiency and validate the model. The study can be used to build a prototype physical model that could be beneficial for future additional experimentation investigation.
Key words: Simulation, cavitation, performance, propeller, CFD
Exposición de José Marín, geólogo de reservorios y especialista en Geomodelación ; fue transmitida en VIVO para la comunidad del Portal de Ingeniería. Para poder ver la charla, ingresa al siguiente enlace: https://www.youtube.com/watch?v=3YJYPQWfuBM
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ocular injury ppt Upendra pal optometrist upums saifai etawah
01 intro & alt physics
1. Introduction Information
1. WELCOME : Primary purpose of attendance - Flight Safety.
Normal body in abnormal environment. Man – machine interface.
2. COFFEE and TEA : Crewroom. SR 2 per person / day.
NO food or drink in the classroom.
3. FIRE. Evacuate via front doors or as directed by Instructor.
4. TOILETS.
5. NO SMOKING.
6. MOBILE PHONES, switched OFF
7. COURSE LEADER.
8. START TIMES and PROGRAMME.
1
2. Introduction Information
11. CONDITIONS : Must be present for all lectures & chamber runs.
12. PRAYER TIME ARRANGEMENTS. Location of mosque.
14. CERTIFICATES.
15. EXAMINATION: Multiple choice, 4 possible answers (only one correct).
Pass mark = 60%.
Failure - Re-sit different exam next day.
- Recourse.
ANY
QUESTIONS.
2
4. Objectives
Describe the structure and layers of the
atmosphere
Explain the change in physical properties with
ascent to altitude
Define the Gas Laws applicable to the
aviation environment
4
5. Layers of the Atmosphere
EXOSPHERE
IONOSPHERE
STRATOSPHERE
TROPOSPHERE
Mt Everest
29,028 ft
TROPOPAUSE
30 MILES
435 MILES
1,200 MILES 5
6. Functions of the Atmosphere
Radiation Protection
UV and sub-atomic particles
Ozone Layer (~ 40K`-140K`)
3 O2 + UV <=> 2 O3 + HEAT
Thermal Protection
Cloud reflects IR radiation (Greenhouse)
Pollutants cause excess....Global Warming
Gaseous Support of Life
O2 , CO2 , H2O
6
7. The ICAO Standard Atmosphere
Where it is / at 45°N in North America.
Air = dry, dust-free, stated composition
Pressure (MSL) = 1013 Hpa
Density (MSL) = 1.225 kg/m3
gconstant = 9.80665m/s2
Temp/alt profile
+15 0C at MSL
Lapse rate = 1.98 0C/1000’ to 36 089’ (= tropopause)
Isothermal layer temp = -56.5 0C
Rises to -46 0C at 100,000’ 7
8. Composition of the Atmosphere
Oxygen 21%
Nitrogen 78%
Rare gases (eg. methane, ozone, CO2) 1%
NB. Although pressure changes with
altitude, this percentage relationship
remains constant
8
9. Problems with Altitude
pO2
Pressure
drops pN2
Gas expands
Temperature drops
(Lapse rate)
Sea Level
9
11. Pressure Changes with Altitude
800
760 1013 HPa
700
600
10,000 ft – 2/3 675.3 HPa
Pressure mm Hg
500
400 18,000 ft – 1/2 506.5 HPa
300 25,000 ft – 1/3 337.6 HPa
33,700 ft – 1/4 253.2 HPa
200
43,000 ft – 1/6
100
0
0 10,000 20,000 30,000 40,000 50,000 60,000
Altitude (Feet).
11
12. The
Gas
Laws
Boyle :
Charles :
Henry :
Dalton : 12
13. The Law of Gaseous Diffusion
Henry’s Law
A gas will move from an area of
higher pressure to an area of lower
pressure.
Oxygenation within the body depends
on this law.
13
14. Partial Pressure
Dalton’s Law
Air at Sea Level
O2 = 21% pO2 = 160 mm Hg
N2 = 78% pN2 = 593 mm Hg
Other = 1% = 7 mm Hg
Total = 100% = 760 mm Hg
14
15. Gas Expansion With Altitude.
Boyle’s Law : PXV=K
800
760 Sea Level – 1/1 1013 HPa
700
600
10,000 ft – 2/3
Pressure mm Hg
675.3 HPa
500
400 18,000 ft – 1/2 506.5 HPa
300 25,000 ft – 1/3 337.6 HPa
33,700 ft – 1/4 253.2 HPa
200
43,000 ft – 1/6
100
0 0
10,000 20,000 30,000 40,000 50,000 60,000
Altitude (Feet).
15
16. Body Cavities Containing Gas (1)
The Middle Ear Nerve to brain
Eardrum
Atmospheric
pressure Atmospheric pressure
Eustachian tube Opening to throat
Atmospheric pressure 16
17. Climbing
Pressure
INCREASES
Eustachian tube
Atmospheric
pressure
DECREASES
Air vents to
throat
17
18. Descending (Normal)
Pressure
DECREASES
Eustachian tube
Atmospheric
pressure
INCREASES
Air must enter via
Eustachian tube.
18
19. Descending (Blocked)
DECREASED
Pressure
PAIN !
Wall of Eustachian
tube sucked in.
Atmospheric
pressure Eardrum sucked in.
INCREASES
BLOCKED.
19
27. Body Cavities Containing Gas (5)
Middle Ear.
Sinuses.
Lungs.
Gastrointestinal Tract.
Post surgical
27
28. Body Cavities Containing Gas (6)
Middle Ear.
Sinuses.
Lungs.
Gastrointestinal Tract.
Post surgical.
Post trauma.
28
29. Body Cavities Containing Gas (7)
Middle Ear.
Sinuses.
Lungs.
Gastrointestinal Tract.
Post surgical.
Teeth.
29
30. Teeth
Problems on Climb :
Bad fillings.
Abscess.
Dental hygiene
is important.
Visit the Dentist
every 6 months.
30
31. Prevention of Trapped Gas Problems
Fly only when healthy
Do not self medicate
Equalise pressures frequently on descent
Avoid gas producing foods, before flying.
31
32. Prevention of Trapped Gas Problems
Never fly with a cold or sore throat.
Do not self medicate.
See the Flight Surgeon if you are sick.
Equalise pressures frequently on descent.
Valsalva or roll the jaw.
Avoid gas-producing foods before flying.
32
33. Physical Changes in the Atmosphere
pO2, Hypoxia above
10,000 ft.
Total atmospheric
pressure falls
pN2, DCI above
18,000 ft.
Gas expands. Sinuses.
Ears.
Stomach.
Temperature falls
2°C / 1000 ft.
Sea level
33
36. Remember
Pain anywhere in the body
DURING CLIMB
=
COMPLETE OBSTRUCTION.
Where
does this
link too ??? 36
Editor's Notes
Information 1. Action. Result. Automatic. Text wipes right by paragraph, 1 sec delay. Click Next slide. Important Points : As per slide.
Introduction 2. Action. Result. Automatic. Text fades in by paragraph, 1 sec delay. Click ‘Any questions’ text. Click Button to Lecture 01 Physics of the Atmosphere. Click Screen to exit to Powerpoint. Important Points : As per slide.
22/07/12 Title Slide. Action. Result. Important Points. An understanding of our atmosphere is useful in all flying operations. It is the environment in which you will be working. To understand effects on our body caused by altitude. Information given in this lesson is essential in understanding the lessons which follow.
22/07/12 Objectives Slide. Action. Result. Important Points.
Layers Slide. Action. Result. Automatic. Earth fades in. 1 sec delay, Everest zooms out. 1 sec delay, rings and titles zoom out 1 sec delay Click. Next slide. Important Points.
22/07/12 Functions Slide. Action. Result. Important Points. Radiation protection - prevents too much UV bombarding the Earth, also subatomic particles, known as “ionising radiation”. The heat generated in the ozone reaction explains why temperature rises in the upper stratosphere. Thermal protection - prevents heat escape and therefore us freezing (eg Mars). Solar radiation heats the ground, which warms the air above it. The ground reradiates IR radiation, which is also reflected back by CO 2 and water vapour...the “Greenhouse Effect”. Major role of heating in forming weather patterns. Gaseous support of Life - oxygen, carbon dioxide and water vapour. We have evolved to exist at the surface of the Earth where these parameters are ideal. As we ascend, these parameters change which impacts on our ability to survive and work at altitude.
22/07/12 ICAO Slide. Action. Result. Important Points. Physical parameters of the atmosphere are defined by the ICAO Standard Atmosphere (ICAO= International Civil Aviation Organisation). Defines an “ideal atmosphere”, which is meant to closely resemble the atmosphere at 45 deg N latitude. Describes the variation of pressure with altitude, for a given relationship between temperature and altitude. Why is this important? A standard which is internationally agreed. Used to calibrate flight instruments, especially altimeters. (Pressure/density height). Allows comparisons between performance of different aircraft types.
22/07/12 Composition Slide. Action. Result. Important Points. These figures are based on dry air only. Usually water vapour is also present; it’s percentage depends on humidity. This water vapour will obviously alter the relationships here by taking up this percentage - more later. For dry air, this percentage relationship holds true up to altitudes approaching 300K’.
Problem Slide. Action. Result. Important Points.
Standard Atmosphere Slide. Action. Result. Important Points.
22/07/12 Pressure Changes Slide. Action. Result. Important Points. How do we measure pressure(units)? Pressure units: 1 atm / bar = 760mm Hg = 101.3kPa = 1013mb / HPa = 14.7psi Sea-level pressures are shown on a weather map using mb. These of course vary with weather patterns. Pressure in the atmosphere is the product of 2 opposing factors: solar radiation, expands gases Earth’s gravity, contracts gases We use mmHg, which are also medical or physiological units. Most measurements of things like the oxygen pressure in your blood (which will be discussed next lecture) are in mmHg however, and therefore it is easier to use these units. Relationship between pressure and altitude is non-linear, ie. exponential Note that the greatest pressure change at lower altitudes. 18000’ is half sea level atmospheric pressure. 25000’ is one third sea level atmospheric pressure. Density follows the same pattern. Von Karman’s line at 262K’, density so low aerodynamic forces do not exist, so vehicles need jets/rockets to manoeuvre. Ask: What is the difference between Pressure and Density? Answer: PRESSURE = FORCE / UNIT AREA DENSITY = MASS / UNIT VOLUME)
22/07/12 Laws Slide. Action. Result. Important Points. These form the basic principles which we will use in subsequent lessons to understand the effects of altitude on the human body. We will be examining five of these Laws.
22/07/12 Henry’s Slide. Action. Result. Important Points. We also see this in weather systems. Winds are caused by air moving from areas of higher to lower pressure. In chemical solutions, molecules also move from areas of high concentration to low concentration. Rate of diffusion depends on: the pressure difference molecular weight, in liquid rate is proportional to the solubility of the gas Fick’s Law, in the human body, where membrane thickness and surface area for diffusion are important. Oxygen diffuses within the body and will be covered in the lesson on Respiration and Circulation
22/07/12 Dalton Slide. Action. Result. Important Points. Dalton’s Law states that the total pressure of a gas (in this case air at 760mmHg) is equal to the sum of the partial pressures of the constituent gases ie Total 760 = 160 + 593 + 7 (constituent gas pressures). It also states that the partial pressure of an individual gas in a mixture is equal to its relative percentage of the total pressure. ie 21% of gas particles in air are O 2, thus 21% of the total air pressure of 760mm Hg is exerted by O 2 , giving a partial pressure of O 2 of 160mm Hg, etc.
22/07/12 18 Boyles Slide. Action. Result. Important Points. A reminder of Boyle’s Law: At constant temperature, the volume of a gas is inversely proportional to its pressure. At 18,000’ the air pressure is half its sea level value, thus a gas will expand to twice its volume if raised to this altitude from sea level at constant temperature. At 25,000’ in the chamber, the air pressure is one third of sea level pressure. Our bodies work hard to maintain a constant core temperature. Gases trapped inside our bodies are therefore maintained at a constant temperature. Thus, gases trapped in our bodies at sea level will expand to three times their original volume as we climb to 25,000’.
Ear (1) Slide. Action. Result. Automatic. Ear zooms in, Labels & arrows zoom in, pressure labels and arrows zoom in, 1 sec delay. Click. Next slide. Important Points.
Climbing Slide. Action. Result. Automatic. Decrease text fades in, arrow wipes right. 1 sec delay, Increase text fades in, arrow wipes left. 1 sec delay, Quad arrow zooms in, arrows wipe down, vent text fades in. Click. Next slide. Important Points.
Normal Descent Slide. Action. Result. Automatic. Increase text fades in, arrow wipes right. 1 sec delay, Decrease text fades in, arrow wipes left. 1 sec delay, Quad arrow zooms out, air text fades in, arrows wipe up. Click. Next slide. Important Points.
Descent Blocked Slide. Action. Result. Automatic. Blocked text zooms out, arrow fly’s up. 1 sec delay, Increase text fades in, arrow wipes right. 1 sec delay, Decrease text fades in, arrow wipes left. 1 sec delay, Quad arrow zooms out, eardrum text fades in, arrows wipe up. Wall text fades in, arrows wipe left. Pain text flash’s 4 times. Click. Next slide. Important Points.
22/07/12 20 Cavities 2 Slide. Action. Result. Important Points. Gas is unlikely to be trapped in the lungs to any significant degree in any scenario in the aviation environment as the large airways conduct the expanding gas easily out of the lungs, through an open epiglottis. If, however, you were able to hold your breath during an explosive decompression this may be sufficient to cause some damage. Certainly this has been shown to occur in diving when breath is held during a rapid ascent to the surface. Damage due to rapid pressure change is known as barotrauma . The pressure differential across the lung must be 80 - 100 mmHg before tearing of the tissues will occur.
22/07/12 Sinuses Slide. Action. Result. Automatic. Text fades in, arrows wipe in, Ethmoid clockwise. Click. Next slide. Important Points. Sinuses are cavities in the skull.
Sinuses (1) Slide. Action. Result. Automatic. Text & arrows zoom in, top to bottom, 1 sec delay. Click. Next slide. Important Points.
22/07/12 20 Cavities 2 Slide. Action. Result. Important Points. Gas is unlikely to be trapped in the lungs to any significant degree in any scenario in the aviation environment as the large airways conduct the expanding gas easily out of the lungs, through an open epiglottis. If, however, you were able to hold your breath during an explosive decompression this may be sufficient to cause some damage. Certainly this has been shown to occur in diving when breath is held during a rapid ascent to the surface. Damage due to rapid pressure change is known as barotrauma . The pressure differential across the lung must be 80 - 100 mmHg before tearing of the tissues will occur.
22/07/12 21 Lungs Slide. Action. Result. Important Points. Conditions which can occur due to lung barotrauma include: Pneumothorax - a tear in the lung allows air to enter the pleural cavity causing a partial collapse of the lung. This causes chest pain and shortness of breath as one is unable to take a normal breath. If the air in the chest is under increased pressure and cannot escape, it is a very serious condition called tension pneumothorax . This can be rapidly fatal if untreated. Air Embolism - a tear in the lung allows air to enter the blood vessels around the lung. Symptoms may include dizziness, shock, headache, vision loss or sudden collapse as blood flow to the brain may be interrupted. These symptoms are similar to stroke. Pneumomediastinum - a tear in the lung allows air to enter the mediastinum, the region between the lungs and around the heart. This causes pain and a shortness of breath. Subcutaneous emphysema - sometimes air may escape into other tissue planes, such as under the skin. This may cause swelling of the tissues around the neck, face and chest, giving a “Michelin Man” appearance. It feels crackly under the fingers, like cellophane paper. Treatment will require medical attention. Small amounts of air will, however, be absorbed from the pleural cavity in time. As a safety measure, and to prevent these conditions from occurring in the chamber, we ensure that we are breathing out at the commencement of any rapid decompression.
22/07/12 22 Cavities 3 Slide. Action. Result. Important Points. It is not uncommon to experience a little “gut” discomfort in an aircraft or in the chamber. This problem is best avoided by paying attention to your diet prior to flying. Avoid gas producing foods such as cabbage, baked beans, and fizzy drinks. On average the healthy gut may contain up to 400ml of gas. Q: At 25,000’, what is the volume of gas in the intestines? Answer: 1.2 litres!
22/07/12 Stomach Slide. Action. Result. Automatic. Text appears, stomach zooms in, 1 sec delay, arrow wipes up. Click. Text appears, Large Int zooms in, 1 sec delay, arrow wipes down. Click. Text appears, Small Int zooms in, 1 sec delay, ? & arrows wipe up/down. Click. Next slide. Important Points.
22/07/12 22 Cavities 3 Slide. Action. Result. Important Points. It is not uncommon to experience a little “gut” discomfort in an aircraft or in the chamber. This problem is best avoided by paying attention to your diet prior to flying. Avoid gas producing foods such as cabbage, baked beans, and fizzy drinks. On average the healthy gut may contain up to 400ml of gas. Q: At 25,000’, what is the volume of gas in the intestines? Answer: 1.2 litres!
22/07/12 22 Cavities 3 Slide. Action. Result. Important Points. It is not uncommon to experience a little “gut” discomfort in an aircraft or in the chamber. This problem is best avoided by paying attention to your diet prior to flying. Avoid gas producing foods such as cabbage, baked beans, and fizzy drinks. On average the healthy gut may contain up to 400ml of gas. Q: At 25,000’, what is the volume of gas in the intestines? Answer: 1.2 litres!
22/07/12 22 Cavities 3 Slide. Action. Result. Important Points. It is not uncommon to experience a little “gut” discomfort in an aircraft or in the chamber. This problem is best avoided by paying attention to your diet prior to flying. Avoid gas producing foods such as cabbage, baked beans, and fizzy drinks. On average the healthy gut may contain up to 400ml of gas. Q: At 25,000’, what is the volume of gas in the intestines? Answer: 1.2 litres!
22/07/12 Body (3) Slide. Action. Result. Automatic. Text wipes down, picture fades in. Click. Dental text zooms in by paragraph. Click. Next slide. Important Points.
22/07/12 34 Prevention Slide. Action. Result. Important Points. It cannot be overstressed to only fly when healthy, even if you only have a head cold. Self medicating may solve the problem on the ground but also may limit inflight treatment options should problems occur. Some medications may have adverse side effects such as drowsiness or decreased Hypoxia tolerance which may impact upon flying safety. See an MO on base to avoid being given incorrect advice or medications for flying. It is impossible to Valsalva too frequently on descent. However, it is important that the correct technique is used. Practice this on the ground. Gas producing foods include beans, cabbage, fizzy drinks, etc - avoid these prior to flight.
Prevention Slide. Action. Result. Automatic. Text wipes right by line, 1 sec delay. Click. Next slide. Important Points.
Changes Slide. Action. Result. Automatic. Pictures, text & arrows wipe in progressively clockwise starting at “sea level” Click. Next slide. Important Points.
22/07/12 22 Cavities 3 Slide. Action. Result. Important Points. It is not uncommon to experience a little “gut” discomfort in an aircraft or in the chamber. This problem is best avoided by paying attention to your diet prior to flying. Avoid gas producing foods such as cabbage, baked beans, and fizzy drinks. On average the healthy gut may contain up to 400ml of gas. Q: At 25,000’, what is the volume of gas in the intestines? Answer: 1.2 litres!
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Prevention Slide. Action. Result. Automatic. Text wipes right by line, 1 sec delay. Click. Next slide. Important Points.