This document outlines an educational presentation on interpreting atypical squamous cells of undetermined significance (ASC-H) cervical cytology samples and related diagnoses. The presentation aims to describe the cytomorphological spectrum of ASC-H, define low-grade squamous intraepithelial lesion-cannot exclude high-grade (LSIL-H), discuss differential diagnoses of hyperchromatic crowded groups, and apply ancillary tests. It is divided into three sections, with the first focusing on morphological evaluation, the second on study cases using two-color immunochemistry, and the third on quality improvement, HPV testing, and medicolegal aspects.