Dr. Peter Simkens discusses how micro/nano-electronics can enable innovative health solutions through a cross-KET approach combining multiple key enabling technologies. Miniaturization allowed by Moore's Law has led to various medical devices like cochlear implants, pacemakers, and insulin pumps. Further miniaturization through micro/nano-electronics, microfluidics, and biotechnology is enabling point-of-care diagnostics and active implantable systems. Emerging industries are being developed through cross-fertilization of semiconductor technology with biotechnology. Dr. Simkens invites participation in building a cross-KET ecosystem for innovative health solutions.

1. Dr.ir. Peter Simkens
Managing Director
Cross-KET Approach to Develop
Innovative Health Solutions

2. Micro/nano-electronics
as Key EnablingTechnology for Medtech
(Single-KET approach)

3. MOORE’S LAW
Number of transistors per square inch on an IC doubles every 18 months
Smaller – higher Computing Performance – less Energy Consumption

4. Success Story
in DSP Valley

5. Finding success-critical technologies in Ultra-Low Power Electronics

6. inside
SMALLER
HIGHER COMPUTING PERFORMANCE
LESS ENERGY CONSUMPTION

7. Cochlear Implant
Bionic Eye
Cardiac Defibrillators
Pace Maker
Gastric Stimulator
Insulin Pumps
Pain Management
Urinary Incontinence
Obstructive Sleep Apnea
Epilepsy Vagus Nerve
Stimulation
Deep Brain Neurostimulator
Cluster Headache
Body wearable and body implantable devices, for monitoring, diagnostics and active stimulation

8. Eye Pressure Sensor for Glaucoma
Smart Health System enabled by Micro/nano-electronics

9. Cross-fertilisation from Semiconductor
Technology to Biotechnology
(Dual KET approach)

10.  Clinical labs
 Trained staff
 Centralised
 Smaller labs
 Hospitals
 Decentralised
Source: Biocartis
Diagnostics: From large scale Clinical Labs to Point-of-Care
Miniaturisation
Enabled by:
• Micro/nano Electronics
• Microfluidics
• Biotechnology
Driven by:
• Miniaturisation
• Automatisation
• Patient autonomy

11.  Smaller labs
 Hospitals
 Decentralised
Source: Biocartis
 Point of care (POC)!!!
 MD’s, nurses, selftest
Source: Rheumachec
Diagnostics: From large scale Clinical Labs to Point-of-Care
Miniaturisation
Enabled by:
• Micro/nano Electronics
• Microfluidics
• Biotechnology
Driven by:
• Miniaturisation
• Automatisation
• Patient autonomy
Mass
Production
Cheap
Consumable

12. Cell Sorting / DNA Sequencing: Miniaturised Compute Power
Enabled by:
• Imaging-on-chip
• Microfluidics
• Microheaters
• ASIC compute power
Compute Power:
massive throughput
20M cells/seconds
Parallellisation

13. Active Implantable Systems: Smart Pills
Enabled by:
• Active biomedical component (drug)
• Microactuator (delivery pump)
• Microcontroller
• Wireless communication
Energy Efficiency
Miniaturisation
Closed loop sensor feedback

14. Easics
OnSemi
Xenics
CMOSIS
Cochlear
eSaturnus
Medtronic
...
Ablynx
Tigenix
Galapagos
Genzyme
ReGenesys
reMynd
ThromboGenics
...
• advanced microscopy
• medical imaging
• biochips (for advanced diagnostics: genetic material, proteins / antibodies)
• active implants (including pumps, drug delivery systems, neurostimulators,...)
Biocartis
J&J
ICsense
AnSem
NXP
Peira
Trinean
Pepric
Ovizio
Agfa
Barco
Icometrix
...
Emerging
Industries
based on
2 KETs

15. Cross-fertilisation with other KET’s
(Cross-KET approach)

16. Miniaturised Plastic Parts

17. European
Cross-KET
Alliances

18. Flemish
Cross-KET
Alliances?
?

19. You are very welcome
to participate in this cross-KET Eco-system,
for Innovative Health Solutions!
peter.simkens@dspvalley.com
+32 16 241 440