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Faculty of Medicine- Alexandria University
Third year (IUMP) - 1st Semester
End Semester Exam
GIT System
Date:15/7/2014 Time allowed:130 minutes
Totalmarks: 55 marks All questions to be answered
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Anatomy
1. Give a short account on otic ganglion regarding its position, roots and
distribution. (3 marks)
2. Enumerate the structures forming the walls of inguinal canal. (3 marks)
3. Give a short account on the relations and arterial supply of stomach. (3 marks)
Pathology
4. Give a short account on the clinical settings for the development of peptic ulcer.
(3 marks)
5. Enumerate the complications of gallstones. (3 marks)
6. Tabulate SIX differences between Ulcerative colitis and Crohn’s disease.
(3 marks)
Physiolgy
7. Discuss functions of saliva. (3 marks)
8. Mention protective reflexes during second phase of deglutition. (3 marks)
9. Discuss types of intestinal motility. (3 marks)
Micro
10.In a picnic , children ate chicken salade only and developed abdominal
cramps and profuse watery diarrhea 2 days after the picnic . Stool culture
on MacConkey agar grows a non lactose fermenting, gram negative bacilli
which is motile, Indole negative & urease negative. (3 marks)
 Which of the following statements about the illness in these children is false ?
a. The pathogenesis of this illness includes the multiplication of the causative organism.
b. A similar syndrome is caused by a small , motile gram negative bacillus with
a gull – wing appearance which grow best on special media at 420 C .
c. A similar syndrome is caused by a gram positive cocci arranged in clusters .
d. This illness has also been associated with eating partially cooked eggs .
 Mention the causative organism in this case. also the organisms mentioned
in (b) and (c)
 Enumerate 2 other causes of toxin mediated food poisoning
11.In a table compare between poliovirus vaccines. (2.5 marks)
Bio
12.Discuss in brief Lactose intolerance (mention cause and pathogenesis). (1.5 marks)
Pharmacology
13.Differentiate between Lansoprazole and Ranitidine regarding
(2.5 marks)
a. Mechanism of action

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b. Optimal timing of administration
c. Clinical uses
14.Recommend the appropriate drug/or drug combination regimen for each of
the following conditions: (2 marks)
a. Prevention of vomiting of a highly emetogenic anticancer drug
b. Treatment of amoebic colitis
c. Treatment of chronic constipation
d. Maintenance of remission in mild crohn’s disease involving the terminal ileum.
Para:
15.A middle aged man suffered from passing bloody stools with excessive
mucous and pus. He also, complained of tenesmus and tenderness over the
caecum. (3 marks)
a. Give the name of two protozoa that could cause this picture?
b. Mention the infective stages of one of them?
c. What is the drug of choice for treating one of them?
16.In a table form differentiate between: (3marks)
- One protozoaand one helminth causing malabsorption as regards; the
infective stage and the mode of infection. (3marks)
17.Give reason:
a. Microcytic hypochromic anaemia occurs in Ancylostoma duodenale infection.
b. Intestinal obstruction may occur in Ascaris infection.
c. The caecum is the commonest site of Entamoeba histolytica infection.
d. Bilharzial corpulmonale occurs in schistosomiasis mansoni.
e. Contact with a food handler passing Taenia eggs in his stool is not dangerous.
f. Oedema occurs in Capillaria philippinesis infection.
Histology:
18.Look to the opposite diagram of the liver, then
answer the following questions: (1.5 marks)
a. Name the cell labeled by 1 and describe the
histological features of the intercellular surface of such
cell.
b. Mention the type of fibers that are commonly present
in the space at 2.
19.Enumerate the lingual papillae that are present in human. Describe the
structure of the largest papilla. (1.5 marks)
20.Tabulate the differences between surface mucous cells and mucous neck
cells of the fundus of the stomach (site – LM picture – type of mucus
secretion). (1.5 marks)
GOOD LUCK