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Faculty of Medicine- Alexandria University
Third year (IUMP) - 1st
Semester
End Semester Exam
GIT System
Date: 15/7/ 2014 Time allowed: 130 minutes
Total marks: 55 marks All questions to be answered
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Anatomy
1. Give a short account on otic ganglion regarding its position, roots and
distribution. (3 marks)
2. Enumerate the structures forming the walls of inguinal canal. (3 marks)
3. Give a short account on the relations and arterial supply of stomach. (3 marks)
Pathology
4. Give a short account on the clinical settings for the development of peptic ulcer.
(3 marks)
5. Enumerate the complications of gallstones. (3 marks)
6. Tabulate SIX differences between Ulcerative colitis and Crohn’s disease.
(3 marks)
Physiolgy
7. Discuss functions of saliva. (3 marks)
8. Mention protective reflexes during second phase of deglutition. (3 marks)
9. Discuss types of intestinal motility. (3 marks)
Micro
10.In a picnic , children ate chicken salade only and developed abdominal
cramps and profuse watery diarrhea 2 days after the picnic . Stool culture
on MacConkey agar grows a non lactose fermenting, gram negative bacilli
which is motile, Indole negative & urease negative. (3 marks)
 Which of the following statements about the illness in these children is false ?
a. The pathogenesis of this illness includes the multiplication of the causative organism.
b. A similar syndrome is caused by a small , motile gram negative bacillus with
a gull – wing appearance which grow best on special media at 420
C .
c. A similar syndrome is caused by a gram positive cocci arranged in clusters .
d. This illness has also been associated with eating partially cooked eggs .
 Mention the causative organism in this case. also the organisms mentioned
in (b) and (c)
 Enumerate 2 other causes of toxin mediated food poisoning
11.In a table compare between poliovirus vaccines. (2.5 marks)
Bio
12.Discuss in brief Lactose intolerance (mention cause and pathogenesis). (1.5 marks)
Pharmacology
13.Differentiate between Lansoprazole and Ranitidine regarding
(2.5 marks)
a. Mechanism of action

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b. Optimal timing of administration
c. Clinical uses
14.Recommend the appropriate drug/or drug combination regimen for each of
the following conditions: (2 marks)
a. Prevention of vomiting of a highly emetogenic anticancer drug
b. Treatment of amoebic colitis
c. Treatment of chronic constipation
d. Maintenance of remission in mild crohn’s disease involving the terminal ileum.
Para:
15.A middle aged man suffered from passing bloody stools with excessive
mucous and pus. He also, complained of tenesmus and tenderness over the
caecum. (3 marks)
a. Give the name of two protozoa that could cause this picture?
b. Mention the infective stages of one of them?
c. What is the drug of choice for treating one of them?
16.In a table form differentiate between: (3marks)
- One protozoa and one helminth causing malabsorption as regards; the
infective stage and the mode of infection. (3marks)
17.Give reason:
a. Microcytic hypochromic anaemia occurs in Ancylostoma duodenale infection.
b. Intestinal obstruction may occur in Ascaris infection.
c. The caecum is the commonest site of Entamoeba histolytica infection.
d. Bilharzial corpulmonale occurs in schistosomiasis mansoni.
e. Contact with a food handler passing Taenia eggs in his stool is not dangerous.
f. Oedema occurs in Capillaria philippinesis infection.
Histology:
18.Look to the opposite diagram of the liver, then
answer the following questions: (1.5 marks)
a. Name the cell labeled by 1 and describe the
histological features of the intercellular surface of such
cell.
b. Mention the type of fibers that are commonly present
in the space at 2.
19.Enumerate the lingual papillae that are present in human. Describe the
structure of the largest papilla. (1.5 marks)
20.Tabulate the differences between surface mucous cells and mucous neck
cells of the fundus of the stomach (site – LM picture – type of mucus
secretion). (1.5 marks)
GOOD LUCK

3. -1-
Faculty of Medicine- Alexandria University
Third year (IUMP) - 1st
Semester
End Semester Exam
GIT System
Date: 15/7/ 2013 Time allowed: 125 minutes
Total marks: 55 marks All questions to be answered
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1. Enumerate origin and branches of the superior mesenteric artery? (3 marks)
2. Discuss parotid gland regarding its relations and lymphatic drainage. (3 marks)
3. Describe the ischiorectal fossa as regard its boundaries and contents. (3 marks)
4. Give the embryological origin of anal canal and two of its congenital
anomalies. (3 marks)
5. List the complications of:
a. Colonic diverticulosis. (3 marks)
b. H. pylori type of chronic gastritis. (3 marks)
6. Enumerate the etiological factors of the hepatocellular carcinoma. (3 marks)
7. Discuss the regulation of pancreatic secretion. (5 marks)
8. Discuss four factors affecting intestinal absorption. (4 marks)
9. Give short account about poliovirus vaccinations. (3marks)
10.Outline the laboratory diagnosis of H.pylori infection. (2.5 marks)
11.Illustrate different mechanisms that are common between glucose
and amino acids absorption. (1.5 marks)
12.Differentiate between Bisacodyl, lactulose and Glycerin suppository,
regarding: (3 marks)
a. Their mechanism of action.
b. Onset of inducing bowel motion.
13.Recommend one drug for each of the following conditions: (1.5 mark)
a. Treatment of erosive esophagitis.
b. Induction of remission in severe ulcerative colitis
c. Symptomatic control of diarrhea in adults

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14.Mention the most probable diagnosis, infective stages and the mode of
infection for the following conditions: ( 3 marks)
a- A 45 year-old man from the Far East complaining of voluminous diarrhoea with
watery stools, abdominal distension and oedema.
b- A 26 year-old man was asked for routine stool analysis before working in a
restaurant. The lab reported the presence of a rounded protozoa cyst with four
nuclei.
15.Differentiate between: (2 marks)
a. Oocyst of Isospora belli and Cryptospridia
b. Cyst of one pathogenic and one commensal amoeba
16.Give reason: (2 marks)
a. Mental retardation in Ancylostomiasis.
b. Malabsorption occurs with Giardia lamblia infection.
17.Where can you find the following parasitic stages: ( 2marks)
a. Cysticercoid larvae of Hymenolepis nana
b. Adult worms of Schistosoma mansoni
18.Examine the figure of the digestive tube and answer the following
questions: (2 marks)
a. Identify the junction in the figure.
b. What is the type of epithelial coverings at sites 1& 2?
c. At site 2, the submucosa fuses with the corium
below the level of ………………………
d. The internal sphincter at site 2 is made up by
…………….
19.Tabulate three light microscopic differences between the serous & mucous
acini of the salivary glands.
(1.5 marks)
20.Describe histologically the surfaces of a hepatocyte. (1 mark)
GOOD LUCK
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5. Faculty of Medicine- Alexandria University
Third year (IUMP) - 2nd
Semester
Reset Exam
GIT System
Date: 2/10/ 2014 Time allowed: 110 minutes
Total marks: 65 marks All questions to be answered
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Anatomy:
Give a short account on:
1. Nerves related to psoas major and their root value. (4 marks)
2. Beginning, termination, and tributaries of inferior vena cava. (4 marks)
3. Draw a diagram showing the relations of the inferior surface of the liver. (3 marks)
4. Give a short note on the development of the stomach. Name two of its congenital
anomalies.
(3 marks)
Pathology:
1. Give a short account on :
a. The gross and microscopic picture of ulcerative colitis. (3 marks)
b. Peptic ulcer as regards: (pathogenesis, most common locations and morphology) (3 marks)

6. 1. Enumerate the different etiologies of cirrhosis (2
marks)
2. Mention the causes of acute pancreatitis. (2
marks)
Physiology:
1. Four functions of saliva. (4 marks)
2. Three types of gastric motility. (3 marks)
3. Functions of gall bladder. (3 marks)
Micro:
1. A 30 year old man has fever for 10 days without obvious cause and without
specific or localizing signs or symptoms. Blood culture grows Gram negative
nonlactose fermenting rods. (Mark 3.5)
a) What is the causative organism.
b) Enumerate biochemical reaction in order to identify this organism.
c) What are the sites is this organism most likely to be found during the carrier state.
d) Name the serological test eventually for detection of antibodies in the serum of such a
patient.
1. A nurse develops clinical symptoms consistent with hepatitis. She recalls
sticking herself with a needle approximately 4 months before after drawing blood
from a patient. Serologic tests for HBsAg, antibodies to HBsAg, and Hepatitis A virus
(HAV) are all negative; however, she is positive for IgM HB core antibody.

7. (Mark 3.5)
a) Discuss the most appropriate diagnosis of this case.
b) Prevention and control of this disease.
Bio:
Give a short note on:

8. 1. Hartnup's disease. (1.5 marks)
2. Absorption of monosaccharides. (1.5 marks)
Pharmacology:
1. Mention 3 Aminosalysilate derivatives with different sites of action in the gut
& specify these different sites. (1.5 mark)
2. Explain the mechanism of action & Specify one therapeutic use for each of the
following: (2 marks)
a. Aprepitant
b. Methylcellulose
1. List 3 adverse effects of Helicobacter pylori eradication regimens. (1.5 mark)
Para:
1. Give reason (s) for the following: (5 marks)
a. Portal hypertension is a complication of Schistosoma mansoni infection.
b. Meat should be properly cooked before eating.
c. Cryptosporidia differ from other coccidian protozoa.
d. Myocarditis can occur in Heterophyes heterophyes infection.

9. a. Praziquantel can be used in the treatment of Hymenolepis nana infection.
1. Name the parasite(s) which can be diagnosed by the following techniques. Me
ntion the parasitic stage that can be found in each. (2marks)
a. Anal swab
b. Entero test capsule
1. Name the parasite (s) which can cause the following: (3 marks)
a. Flask shaped ulcers in the large intestine
b. Rectal prolapse
c. Appendicitis
d. Halzoun
Histology:
1. Mention the histological changes that take place at the pyloro-duodenal
junction.
(2 marks)
1. Describe the histological characteristics of the following:
a. Absorptive columnar cell of the small intestine (enterocyte) referring to its adaptation
to perform its function. (2 marks)
b. A section in the gall bladder. (2 marks)
GOOD LUCK