glomeruli kidney inflammation
Alternative names: acute/chronic nephritis,
Definition: Type of kidney disease in which the
part of the kidneys that help filter waste and
fluids from the blood is damaged.
Damage to the glomeruli causes blood and
protein to be lost in the urine.
Glomeruli – The filters of the kidneys which filter the
blood and make urine.
Often, the precise cause of glomerulonephritis is
Glomerulonephritis may be caused by specific
problems with the body's immune system.
Most common symptoms:
Hematuria (dark, brown, or rusty colored,)
Swelling of the face, eyes, ankle, feet, legs,
Symptoms which may also appear include:
Loss of appetite
Shortness of breath
History of cancer
Blood or lymphatic disorders
Exposure to hydrocarbon solvents
Because symptoms develop gradually, the
disorder may be discovered when there is an
abnormal urinalysis during a routine physical or
examination for unrelated disorders.
Tests and Clinical Procedures
Abdominal CT scan
Intravenous Pyelogram (IVP)
Urinalysis and other urine tests:
Urine concentration test
Urine specific gravity
Treatment varies depending the type and severity
High blood pressure may be difficult to control,
and it is generally the most important aspect of
Medicines that may be prescribed include:
Blood pressure medications are often needed to
control high blood pressure.
Medications that suppress the immune system may
also be prescribed, depending on the cause of the
Glomerulonephritis may be a temporary and
reversible condition, or it may get worse.
Progressive glomerulonephritis may lead to
chronic kidney failure and end-stage kidney
12 year old girl who visited the doctor in distress.
Has been passing rusty colored urine.
Looked puffy around the face.
High blood pressure.
Doctor saw previous antibiotics given for streptococcal infection
in her records.
Doctor used test strip to test urine.
Resulted in presence of protein.
Blood test was arranged
Blood test suggested an autoimmune response had damaged part
of the kidneys nephrons.
Doctor suggested she be closely watched for the time being and
blood pressure monitored.
Her condition fortunately cleared up after a few months.